Bad viruses travel fast: Measles vaccine important for travelers

The United States was declared free from ongoing measles transmission in 2000. But we may be at risk for joining the U.K, Greece, Albania, and the Czech Republic, four countries recently stripped of measles elimination status by the World Health Organization. Since the beginning of 2019, more than 1,234 measles cases have been reported in 31 states, with active outbreaks in upstate New York and El Paso, Texas. New York has just declared the end of its yearlong outbreak, which required a massive public health response to control. Minnesota had a major measles outbreak in 2017. In 2015, 125 cases of measles occurred in California, and in 2014, 383 people were infected with measles in an Amish community in Ohio. Beyond our borders, measles outbreaks have also been a big problem in Europe and elsewhere – a point to be aware of if you’re traveling. How measles outbreaks happen There are several reasons why we are still at risk for measles outbreaks. Travelers may get infected overseas, and bring the measles virus back into the country with them unawares. The 2015 measles outbreak in Ohio began when two infected members of the Amish community returned home from typhoon relief work on the Philippines. The California measles outbreak in 2014 started at two Disney theme parks, perhaps after the virus was brought there by a foreign tourist. In measles, there is an unusually long delay between infection and the development of the rash and other symptoms, typic...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Infectious diseases Prevention Travel health Source Type: blogs

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In this study, structural proteins of MERS-CoV were expressed in silkworm larvae and Bm5 cells for the development of vaccine candidates against MERS-CoV and diagnostic methods. The spike (S) protein of MERS-CoV lacking its transmembrane and cytoplasmic domains (SοTM) was secreted into the hemolymph of silkworm larvae using a bombyxin signal peptide and purified using affinity chromatography. The purified SοTM forms small nanoparticles as well as the full-length S protein and has the ability to bind human dipeptidyl peptidase 4 (DPP4), which is a receptor of MERS-CoV. These results indicate that bioactive S...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
Publication date: November 2019Source: Fish &Shellfish Immunology, Volume 94Author(s): Jing Wang, Jia-Jia Du, Biao Jiang, Run-Zhen He, An-Xing LiAbstractShort-term feed deprivation or fasting is commonly experienced by aquaculture fish species and may be caused by seasonal variations, production strategies, or diseases. To assess the effects of fasting on the resistance of Nile tilapia to Streptococcus agalactiae infection, vaccinated and unvaccinated fish were fasted for zero, one, three, and seven days prior to infection. The cortisol levels of both vaccinated and unvaccinated fish first decreased and then increased ...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: Available online 12 October 2019Source: Multiple Sclerosis and Related DisordersAuthor(s): Shahin Khayambashi, Amber Salter, Tuula Tyry, Gary R Cutter, Robert J Fox, Ruth Ann MarrieAbstractObjectiveWe aimed to determine the association between gender identity and sexual orientation on healthcare-related utilization in persons with multiple sclerosis (MS), as well as satisfaction with their doctor and comfort discussing sexual health with their doctor.MethodsWe surveyed participants from the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry regarding their gender identity and sexua...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
How to find the faint stars of the water bearer, identified by the Babylonians with their water god EaAquarius, the water bearer, is one of the northern hemisphere ’s autumnal constellations. It is a faint grouping of stars, found between Capricornus and Pisces, and must be viewed from a dark site. The chart shows the view looking south-south-west at midnight BST on 14 October. Fomalhaut (inPiscis Austrinus) is the brightest star in this section of the sky. Find it low down on the horizon and then, looking above it, begin to trace out the body of Aquarius, hopping from one faint star to the other. The constellation i...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Science Astronomy Space Source Type: news
ConclusionsBronchodilator dose responsiveness may be useful for phenotyping and may be of utility in practice and future studies focused on asthma outcomes or quantification of treatment responses. In children and adolescents, this phenotype of poor bronchodilator responsiveness may be associated with periods of relatively stable disease yet marked airway constriction in response to triggers, including tobacco smoke, respiratory infections/pneumonia, and aeroallergens.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
This study aimed to assess the risk factor for mortality owing to VAP. MATERIAL AND METHODS This retrospective clinical audit study screened medical records between the period of January 2014 and December 2017. All patients under mechanical ventilation MV) for ≥72 hours were screened against previously reported diagnostic criteria for VAP. The medical records were obtained for cases of documented diagnosis of VAP. RESULTS In all, 145 patients (5.0%) diagnosed with VAP were included in the study; the morbidity of VAP was 19.5 episodes per 1000 days of MV. The 30-day mortality rate was 42.8%. Univariate logistic analysis ...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
John SamplesElizabeth Warren ’s presidential campaign has a new Facebook ad claiming Mark Zuckerberg, the CEO of Facebook, has endorsed Donald Trump for re-election. That claim is false, and Warren admits as much in the ad. Warren is not trying to mislead people about Zuckerberg. She is trying to control what can be said on Facebook. That is much more dangerous than any lie appearing in a campaign ad.Recently the Trump campaign ran an ad on Facebook saying former vice president Joe Biden had sought to fire a Ukrainian prosecutor investigating a company whose board included Biden ’s son. Many on the left like Wa...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
Publication date: Available online 12 October 2019Source: Journal of Neuroscience MethodsAuthor(s): Cristina Miliano, E. Reilly Scott, Laura B. Murdaugh, Emma R. Gnatowski, Christine L. Faunce, Megan S. Anderson, Malissa M. Reyes, Ann M. Gregus, Matthew W. BuczynskiAbstractSmoking tobacco products is the leading cause of preventable death worldwide. Coordinated efforts have successfully reduced tobacco cigarette smoking in the United States; however, electronic cigarettes (e-cigarette) and other electronic nicotine delivery systems (ENDS) recently have replaced traditional cigarettes for many users. While the clinical risk...
Source: Journal of Neuroscience Methods - Category: Neuroscience Source Type: research
Publication date: Available online 12 October 2019Source: Veterinary MicrobiologyAuthor(s): Haiyan Sun, Jung-Hyang Sur, Sarah Sillman, David Steffen, Hiep L.X. VuAbstractThe substantial genetic diversity exhibited by influenza A viruses of swine (IAV-S) represents the main challenge for the development of a broadly protective vaccine against this important pathogen. The consensus vaccine immunogen has proven an effective vaccinology approach to overcome the extraordinary genetic diversity of RNA viruses. In this project, we sought to determine if a consensus IAV-S hemagglutinin (HA) immunogen would elicit broad protective ...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
(This post has been updated with relevant recent information.) The United States was declared free from ongoing measles transmission in 2000. But we may be at risk for joining the UK Greece, Albania, and the Czech Republic, four countries recently stripped of measles elimination status by the World Health Organization. Since the beginning of 2019, more than 1,234 measles cases have been reported in 31 states, with active outbreaks in upstate New York and El Paso, Texas. New York has just declared the end of its yearlong outbreak, which required a massive public health response to control. Minnesota had a major measles outb...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Infectious diseases Prevention Travel health Source Type: blogs
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