Research and Reviews in the Fastlane 051

Welcome to the 51st edition of Research and Reviews in the Fastlane. R&R in the Fastlane is a free resource that harnesses the power of social media to allow some of the best and brightest emergency medicine and critical care clinicians from all over the world tell us what they think is worth reading from the published literature. This edition contains 10 recommended reads. The R&R Editorial Team includes Jeremy Fried, Nudrat Rashid, Soren Rudolph, Anand Swaminathan and, of course, Chris Nickson. Find more R&R in the Fastlane reviews in the R&R Archive, read more about the R&R project or check out the full list of R&R contributors This Edition’s R&R Hall of Famer Emergency Medicine, Critical Care, Resuscitation The ARISE Investigators and the ANZICS Clinical Trials Group, Goal-Directed Resuscitation for Patients with Early Septic Shock. NEJM 2014. PMID: 25272316 Early Goal Directed Therapy (EGDT) has already come under fire after publication of the ProCESS trial. ARISE goes even further. This multinational RCT demonstrates that modern usual care is equivalent to EGDT in terms of outcomes (90-day all cause mortality). The usual care arm had lower rates of CVL placement and blood transfusion. ARISE is important because unlike ProCESS, all of the participating centers were not academic institutions. EGDT was practice changing but putting it to pasture will hopefully allow us to focus in the critical pieces of management that make t...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Anaesthetics Cardiology Education Emergency Medicine Gastroenterology Infectious Disease Intensive Care Pre-hospital / Retrieval Respiratory Resuscitation critical care literature R&R in the FASTLANE recommendations Research an Source Type: blogs