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The effect of local and systemic statin use as an adjunct to non-surgical and surgical periodontal therapy —A systematic review and meta-analysis
ConclusionsSignificant additional clinical and radiographic improvements are obtained after local, but not systemic, statin use as an adjunct to SRP in deep pockets associated with intrabony defects and seemingly with furcation defects; intrasurgical statin application seems similarly beneficial. Confirmation of these results, and especially of the effect size, from other research groups is warranted. (Source: Dental Technology Blog)
Source: Dental Technology Blog - October 20, 2017 Category: Dentistry Source Type: news

AstraZeneca ’ s Cancer Drug Trial Disappoints, Sending Shares Lower
The treatment had been expected to be a crucial driver of growth for the company as it faces more competition from generic pharmaceuticals. (Source: NYT Health)
Source: NYT Health - July 27, 2017 Category: Consumer Health News Authors: PRASHANT S. RAO Tags: Inventions and Patents Drugs (Pharmaceuticals) Crestor (Drug) AstraZeneca PLC Source Type: news

Heart Attack Survivors Often Fail to Take Statins
Most patients in a large study either took less of the lifesaving medicines than needed or stopped taking the drugs entirely within two years. (Source: NYT Health)
Source: NYT Health - April 24, 2017 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Heart Crestor (Drug) Statins (Cholesterol-Lowering Drugs) Source Type: news

Tackling a Decade of Change
There has never been a more exciting time to be in the pharmaceutical industry – if you like change, that is. While change is a constant in business, pharma has experienced unprecedented levels over the past decade, says Alistair Grenfell, President, North Europe, Middle East and Africa, at QuintilesIMS.“At a time when we are seeing a huge amount of innovation in our science and our pipeline – creating great excitement among the healthcare community – we need to acknowledge that our world has changed,” says Grenfell. “If you wind the clock back to 2005 and look at the top 10 selling medi...
Source: EyeForPharma - March 23, 2017 Category: Pharmaceuticals Authors: Hugh Gosling Source Type: news

Zocor (simvastatin) vs. Crestor (rosuvastatin)
Title: Zocor (simvastatin) vs. Crestor (rosuvastatin)Category: MedicationsCreated: 3/17/2017 12:00:00 AMLast Editorial Review: 3/17/2017 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - March 17, 2017 Category: Cardiology Source Type: news

CardioBreak: Medicare Money for Micra; Stent Retriever Wins, Warnings; Crestor Switcheroo
(MedPage Today) -- Recent developments of interest in cardiovascular medicine (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - March 13, 2017 Category: Cardiology Source Type: news

Health Care Special Report: KU doc finds cancer hope
After years of treating patients, researching cancer and testing treatments, Tomoo Iwakuma made the discovery of his lifetime: Statins, typically used to lower cholesterol levels, could treat some types of cancer. An associate professor at the University of Kansas Medical Center, Iwakuma thinks that statins — such as brand names Crestor and Lipitor — could be used to treat 10 to 20 percent of cancer patients with a mutation in a tumor suppressor protein called p53. This mutation is found in… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - February 3, 2017 Category: Pharmaceuticals Authors: Elise Reuter Source Type: news

AstraZeneca hit by falling sales of bestsellers
Declines in Crestor and Nexium offset emerging markets growth   (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - February 2, 2017 Category: Pharmaceuticals Source Type: news

Rosuvastatin Calcium Tablets (rosuvastatin calcium) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 12, 2017 Category: Drugs & Pharmacology Source Type: news

Patient With Chest Pain and Shortness of Breath Shows Standardized Treatment Doesn't Work for All Patients
John, a 65-year-old male, is sitting in a chair in the corner of the room as you and your partner enter his house. John tells you he's the only one home and called 9-1-1 because he can't breathe and his chest is killing him. His skin is ashen and his breathing is rapid. You can palpate a weak irregular pulse and you note his skin is warm and diaphoretic. He describes his shortness of breath as increasing in severity over the last couple of hours with the chest discomfort. With a pulse oximetry reading of 78% on room air, you apply oxygen via a non-rebreathing mask. Physical exam reveals bibasilar crackles on pulmonary ausc...
Source: JEMS Patient Care - December 30, 2016 Category: Emergency Medicine Authors: Dennis Edgerly, EMT-P Tags: Columns Patient Care Source Type: news

Statins may influence risk of Alzheimer ’s
Risk reduction depends on specific statin and ethnicity and sex of patient Related items fromOnMedica US doctor says FDA should have withdrawn rosuvastatin Detection bias may be behind memory loss with statins Statins might not cut colorectal cancer risk after all Major review clears statins US expert group updates statins recommendations (Source: OnMedica Latest News)
Source: OnMedica Latest News - December 13, 2016 Category: UK Health Source Type: news

Pharma withheld faulty device info in rivaroxaban trial
Patients must live with uncertainty until concerns over key trial data are addressed Related items fromOnMedica Extending anticoagulation duration cuts risk of VTE recurrence Metformin lowers cardiac deaths better than other drugs US doctor says FDA should have withdrawn rosuvastatin NICE calls for safer use of controlled drugs BMJ questions trial evidence for rivaroxaban (Source: OnMedica Latest News)
Source: OnMedica Latest News - September 28, 2016 Category: UK Health Source Type: news

Rosuvastatin Slows Progression of Atherosclerosis in HIV Rosuvastatin Slows Progression of Atherosclerosis in HIV
Find out what there is to know about the effect of rosuvastatin on subclinical atherosclerosis among HIV-infected individuals receiving antiretroviral therapy.AIDS (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - September 23, 2016 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Crestor (Rosuvastatin Calcium) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 1, 2016 Category: Drugs & Pharmacology Source Type: news

A new method cuts the cost of drug-building chemicals
EPFL (École polytechnique fédérale de Lausanne) scientists design a new method to cheaply produce some of the most important chemical compounds in the pharmaceutical industry - the amines. The amines are one of the most important classes of chemical compounds today. Amines that contain a ring-like structure - called an "aryl" group - are used widely in pharmaceuticals, such as the top-selling drugs Abilify, Crestor, Gleevec, and Lidoderm. (Source: World Pharma News)
Source: World Pharma News - August 12, 2016 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

AstraZeneca helped by new drugs as cholesterol pill fades
LONDON (Reuters) - Generic competition to cholesterol buster Crestor in the U.S. market pushed second-quarter core earnings down by nearly a third at drugmaker AstraZeneca, which is now banking on new cancer medicines to revive its fortunes. (Source: Reuters: Health)
Source: Reuters: Health - July 28, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

CardioBreak: Generic Crestor; Specialization Saves Lives; Catheter Recall
(MedPage Today) -- Recent developments of interest in cardiovascular medicine (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - July 25, 2016 Category: Urology & Nephrology Source Type: news

Morning Break: Generic Crestor OK'd; High Priestess of Snake Oil; Pain Refugees
(MedPage Today) -- Health news and commentary from around the Web, gathered by the MedPage Today staff (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - July 21, 2016 Category: Psychiatry Source Type: news

FDA Approves Additional Generic Versions of Rosuvastatin (FREE)
By the Editors The FDA has approved several more generic versions of rosuvastatin (Crestor), the New York Times reports. The first … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 20, 2016 Category: Primary Care Source Type: news

Judge Rules Against AstraZeneca's Plea to Ban Crestor Generics
Generic manufacturers can now enter the $5 billion cholesterol drug market (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - July 20, 2016 Category: Pharmaceuticals Source Type: news

Judge Rules Against AstraZeneca's Plea to Ban Crestor Generics
Generic manufacturers can now enter the $5 billion cholesterol drug market (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - July 20, 2016 Category: Pharmaceuticals Source Type: news

Mylan Launches Generic Crestor(R) Tablets
HERTFORDSHIRE, England and PITTSBURGH, July 20, 2016 -- (Healthcare Sales & Marketing Network) -- Mylan N.V. (NASDAQ, TASE: MYL) today announced the U.S. launch of Rosuvastatin Calcium Tablets, 5 mg, 10 mg, 20 mg and 40 mg, which is a generic version of A... Biopharmaceuticals, Generics, FDA, Product LaunchMylan, Rosuvastatin, Crestor, AstraZeneca (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 20, 2016 Category: Pharmaceuticals Source Type: news

Generic Crestor Wins Approval, Dealing a Blow to AstraZeneca
The F.D.A. allowed eight generics of the cholesterol-lowering pill to go on the market, a move that should considerably decrease its price. (Source: NYT Health)
Source: NYT Health - July 20, 2016 Category: Consumer Health News Authors: ANDREW POLLACK Tags: Crestor (Drug) Drugs (Pharmaceuticals) Generic Brands and Products AstraZeneca PLC Food and Drug Administration Source Type: news

Sun Pharma gets FDA nod for rosuvastatin calcium tablets
Sun Pharma said: "One of its subsidiaries has received final approval from USFDA for its Abbreviated New Drug Application (ANDA) for generic version of Crestor. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 20, 2016 Category: Pharmaceuticals Source Type: news

Aurobindo Pharma gets FDA nod for rosuvastatin calcium tabs
Aurobindo Pharma has received final approval from the US health regulator USFDA for rosuvastatin calcium tablets, used in lowering cholesterol. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 20, 2016 Category: Pharmaceuticals Source Type: news

Glenmark gets FDA nod for rosuvastatin calcium tablets
Quoting IMS sales data for the 12 months to May 2016, Glenmark said Rosuvastatin calcium tablets achieved annual sales of around USD 6.78 billion. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 20, 2016 Category: Pharmaceuticals Source Type: news

Judge refuses to block generic versions of AstraZeneca's Crestor
(Reuters) - A U.S. judge on Tuesday refused to issue a temporary restraining order blocking the approval of new generic versions of AstraZeneca's blockbuster cholesterol drug Crestor in the United States. (Source: Reuters: Health)
Source: Reuters: Health - July 19, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

rosuvastatin, Crestor
Title: rosuvastatin, CrestorCategory: MedicationsCreated: 10/22/2003 12:00:00 AMLast Editorial Review: 7/12/2016 12:00:00 AM (Source: MedicineNet Cholesterol General)
Source: MedicineNet Cholesterol General - July 12, 2016 Category: Cardiology Source Type: news

AstraZeneca Sues FDA to Block Generic Crestor
With several ANDAs for generic versions of cholesterol treatment Crestor awaiting approval by the FDA, AstraZeneca is suing the agency to prevent approvals prior to May 2023. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - June 30, 2016 Category: Pharmaceuticals Source Type: news

AstraZeneca Pushes to Protect Crestor From Generic Competition
The drug maker is trying to get its popular anticholesterol pill approved to treat children who have a rare disease characterized by high cholesterol. (Source: NYT Health)
Source: NYT Health - June 27, 2016 Category: Consumer Health News Authors: ANDREW POLLACK Tags: Crestor (Drug) Law and Legislation Cholesterol AstraZeneca PLC Drugs (Pharmaceuticals) Children and Childhood Generic Brands and Products Food and Drug Administration Source Type: news

Rosuvastatin vs Placebo in Sepsis-Associated ARDSRosuvastatin vs Placebo in Sepsis-Associated ARDS
How do patients with sepsis and acute respiratory distress syndrome fare one year after treatment with rosuvastatin? Thorax (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - May 18, 2016 Category: Intensive Care Tags: Pulmonary Medicine Journal Article Source Type: news

Perioperative Rosuvastatin Not Beneficial in Cardiac-Surgery Patients (FREE)
By Joel M. Gore, MD Dr. Gore in an associate editor for NEJM Journal Watch Cardiology, from which this story was adapted. See full coverage at the link below.Perioperative rosuvastatin doesn't reduce postoperative complications in patients … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 4, 2016 Category: Primary Care Source Type: news

Perioperative Rosuvastatin Fails to Curb Cardiac Surgery ComplicationsPerioperative Rosuvastatin Fails to Curb Cardiac Surgery Complications
Although the adverse effects on renal function may relate to patient ethnicity or rosuvastatin use, "a class effect of statin therapy in patients undergoing cardiac surgery cannot be ruled out," the authors said. Heartwire from Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 4, 2016 Category: Consumer Health News Tags: Cardiology News Source Type: news

No Statins Before Heart Surgery, Study Suggests
WEDNESDAY, May 4, 2016 -- Taking cholesterol-lowering statins right before heart surgery, once touted as a way to prevent common postoperative complications, has no benefit and may even cause harm, a new study suggests. In that setting, Crestor... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 4, 2016 Category: Journals (General) Source Type: news

Allergan Receives FDA Approval and Launches First Generic Version of CRESTOR(R) (rosuvastatin)
DUBLIN, May 2, 2016 -- (Healthcare Sales & Marketing Network) -- Allergan plc (AGN), a leading global pharmaceutical company, today confirmed that it has received final approval from the U.S. Food and Drug Administration (FDA) on its Abbreviated New Drug ... Biopharmaceuticals, Generics, FDA, Product LaunchAllergan, CRESTOR, rosuvastatin, AstraZeneca (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 2, 2016 Category: Pharmaceuticals Source Type: news

CardioBrief: Rosuvastatin Goes Generic, Major Role Expected
(MedPage Today) -- Finally there's a challenger to the long reign of atorvastatin, experts say (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - May 2, 2016 Category: American Health Source Type: news

CardioBreak: Generic Crestor, New LAA Closure Device, Health Check Flop
(MedPage Today) -- Recent developments of interest in cardiovascular medicine (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - May 2, 2016 Category: Cardiology Source Type: news

Generic Crestor Approved (FREE)
By the Editors The first generic version of Crestor (rosuvastatin) has been … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 1, 2016 Category: Primary Care Source Type: news

D.C. Week: Medicare Reforms Backed Up With New Rules
(MedPage Today) -- Also, FDA approval for the first generic version of Crestor (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - April 30, 2016 Category: American Health Source Type: news

Monthly News Roundup - April 2016
First-Time Generic Approved for Statin Crestor High cholesterol, high low-density lipoprotein (LDL) or “bad cholesterol”, and triglycerides increase the risk for serious heart disease and may lead to heart attacks and strokes. The FDA has now... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 30, 2016 Category: Pharmaceuticals Source Type: news

FDA Approves First Generic Crestor
April 29, 2016 -- The U.S. Food and Drug Administration today approved the first generic version of Crestor (rosuvastatin calcium) tablets for the following uses: in combination with diet for the treatment of high triglycerides... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 29, 2016 Category: Pharmaceuticals Source Type: news

Generic Crestor Approved by FDA
(Source: WebMD Health)
Source: WebMD Health - April 29, 2016 Category: Consumer Health News Source Type: news

FDA Approves Generic Rosuvastatin (Crestor)FDA Approves Generic Rosuvastatin (Crestor)
Rosuvastatin goes off patent and presumably plunges in price, at a time when clinicians overall have been lukewarm about prescribing the comparatively expensive, recently approved PCSK9 inhibitors. FDA Approvals (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 29, 2016 Category: Cardiology Tags: Cardiology News Alert Source Type: news

FDA approves first generic Crestor
The U.S. Food and Drug Administration today approved the first generic version of Crestor (rosuvastatin calcium) tablets for the following uses (Source: Food and Drug Administration)
Source: Food and Drug Administration - April 29, 2016 Category: American Health Source Type: news

The Oversimplification of Cholesterol Testing Can Be Deadly
Early every year, countless Americans embark on a new fitness regime. They go for a physical and maybe for a blood test to measure cholesterol levels. After a clean bill of health, they might train to run a 10K, a marathon or even an Iron man. But what if those tests do not provide a complete picture of your health? What if you are on the verge of a heart attack and have no idea? Before 30, when the human body is at its peak, it can take the strain of being pushed to the limit. As we age, however, cellular changes and the expression of genetic predispositions can dramatically alter our health. Conventional medical tests a...
Source: Healthy Living - The Huffington Post - April 6, 2016 Category: Consumer Health News Source Type: news

Some People Really Can't Take Statins For High Cholesterol, Scientists Prove
You can't write a story about the lifesaving benefits of the cholesterol-lowering drugs called statins without getting comments like this one, from reader Bill Hayman, on my story yesterday: I cannot take Crestor or Zetia or any form of statin drug! I can barely walk with any statin drug. My legs become painful and so weak, they feel like rubber. Several years ago, I used Lipitor and had four pancreatic attacks until I stopped the Lipitor. Or this, from reader James Leedy: People should be warned of side effects. Doctors should listen to patients . I have taken statins for several years. I had extreme muscle pains all t...
Source: Forbes.com Healthcare News - April 3, 2016 Category: Pharmaceuticals Authors: Matthew Herper Source Type: news

HOPE-3: Statins Lower CV Events in Intermediate-CHD-Risk PatientsHOPE-3: Statins Lower CV Events in Intermediate-CHD-Risk Patients
Alone or with blood-pressure-lowering therapy, at least in those with elevated baseline BP, rosuvastatin lowered composite end points by 24% to 29% vs placebo. Heartwire from Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 2, 2016 Category: Cardiology Tags: Cardiology News Source Type: news

India's Biocon Gets EU Approval for Generic Crestor
This marks the company's first generic formulations approval in the regulated markets (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - February 16, 2016 Category: Pharmaceuticals Source Type: news