The 8th Annual Alexander Awards: The Best Tox Reading of 2017

Alexander Gettler Once again, last year’s outstanding examples of long-form journalism dealing with topics related to medical toxicology were dominated by coverage of the opioid crisis, its origins and the resulting carnage. The must-read article of the year was “The Family That Built a Empire of Pain,” Patrick Radden Keefe’s massive history of the Sacklers, one of America’s richest clans, much of whose wealth comes from their ownership of Purdue Pharma and the marketing and distribution of Oxycontin. The article, which appeared in the New Yorker, notes that the clan’s patriarch, Arthur Sackler, worked his way through medical school in the 1940s by serving as a copywriter for a New York ad agency that targeted targeted physicians and medical workers. He was so successful at melding the then disparate worlds of Marcus Welby M.D. and Don Draper that ultimately he took over the entire company: “Until then, pharmaceutical companies had not availed themselves of Madison Avenue pizazz and trickery. As both a doctor and an adman, Arthur displayed a Don Draper-style intuition for the alchemy of marketing. He recognized that selling new drugs requires a seduction of not just the patient but the doctor who writes the prescription.” Sackler began using medical thought leaders to endorse specific products. Keefe quotes psychiatrist Allen Frances: “Most of the question practices that propelled the pharmaceutical industry into the ...
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical 2017 Alexander awards opioids Purdue Pharma Sackler Source Type: news

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In this study, the authors employed multielectrode arrays to investigate the short-term effects of x-ray radiation on the electrophysiological behavior of cardiomyocytes derived from human-induced pluripotent stem cells. These cardiomyocytes with spontaneous pacemaker activity were cultured on single-well multielectrode arrays. After exposure to 0, 0.5, 1, 2, 5, 10 Gy x-ray radiation, electrical activity was measured at time points ranging from 10 min to 96 h. RNA sequencing was employed to verify the expression of genes specifically involved in cardiomyocyte differentiation and function. A decrease in beating rate was obs...
Source: Health Physics - Category: Radiology Tags: Papers Source Type: research
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Source: Journal of Orthopaedic Trauma - Category: Orthopaedics Tags: Original Article Source Type: research
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Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
Source: BMJ Comments - Category: General Medicine Source Type: forums
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Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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By MEGHAN CONROY These days I’m spending a lot of time getting in depth with many tech companies. From time to time I’ll be asking those innovators to tell their story on THCB, and suggest what problems they are solving. First up is Meghan Conroy from Captureproof—Matthew Holt Today’s doctors are communicating with their patients less than ever before, even as their days grow longer and busier. Physicians are pressured to see more patients in shorter encounters, while at the same time shouldering more of the administrative and documentation tasks associated with electronic medical records (EMR). The...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Health 2.0 Captureproof Meghan Conroy Source Type: blogs
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