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Diabetes is not genetic

She was a beautiful woman. A patient who was easy for me to relate to. When she started to weep, I understood. I’ve heard stories like hers hundreds of times since the beginning of my career, back in Lake Worth in 1992. Let me tell you why I think this is important for you. She said, “My doctor told me I have diabetes, and it’s incurable.” So I told her, you’re not broken. There is no gene for type 2 diabetes. The things we’ve been telling people about diabetes being genetic is just dead wrong. Research has shown that genetic predispositions for most chronic diseases explain very little about disease.1 That’s because it’s environmental. The message this woman’s doctor sent her was that there was something broken inside of her. The truth is, we’ve been doing this to her with the abnormal environment we’ve created. This environmental shift started when our ancestors went from hunting for food, to farming. I always say that when you solve one problem, you create another. This transformation from a meat- and berry-based diet — what I call primal — to a grain-based diet has left us weak and diseased. Here’s an example of how much our food has changed… Wild wheat contained 14 chromosomes. Soon after humans started to grow domesticated crops, hybrid varieties of wheat evolved to have 28 chromosomes. Today’s genetically modified version — what I call a Frankenfood — has an ama...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Natural Cures Nutrition Chronic diseases diabetes diet Glycemic glycemic index GMO grains high Glycemic foods low-glycemic food Syndrome Zero Source Type: news

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Shanhu Qiu, Xue Cai, Zilin Sun, Martina Z ügel, Jürgen M. Steinacker, Uwe Schumann
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Authors: Briganti SI, Gaspa G, Tabacco G, Naciu AM, Cesareo R, Manfrini S, Palermo A Abstract In humans, irisin is produced mainly by skeletal muscle in response to physical activity. It has been demonstrated that irisin plays a pivotal role in inducing fat browning and regulating energy expenditure. New findings from various studies conducted in both animals and humans suggest that irisin can affect bone and glucose metabolism. In particular, irisin is able to increase bone cortical mass by stimulating the osteoblast pathways, and irisin levels are inversely correlated with the incidence of fragility fractures amo...
Source: Minerva Endocrinologica - Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Conclusion: IR might be a risk factor for thyroid nodule. Whether alleviating the IR might slow the growth, or diminish the volume and size of the thyroid nodules, is yet to be elucidated. PMID: 29158735 [PubMed]
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
ABSTRACT: The consumption of sugars, particularly sugar-sweetened beverages (SSBs; beverages or drinks that contain added caloric sweeteners (ie, sucrose, high-fructose corn syrup, fruit juice concentrates), in European children and adolescents exceeds current recommendations. This is of concern because there is no nutritional requirement for free sugars, and infants have an innate preference for sweet taste, which may be modified and reinforced by pre- and postnatal exposures. Sugar-containing beverages/free sugars increase the risk for overweight/obesity and dental caries, can result in poor nutrient supply and reduced d...
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Society Paper Source Type: research
Conclusion Treatment with curcumin can significantly improve the metabolic disorder of glucose and lipid, enhance the sensitivity to the insulin, and ameliorate the resistance to insulin of the type II DM rats. Meanwhile, this treatment method can also significantly decrease the level of FFA and TNF-α in serum of type II DM rats. Thus, we inferred that the mechanism of curcumin to improve the insulin resistance might be correlated with the decreases of FFA and TNF-α in serum.
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
All the patients that I see in my clinic are special… But sometimes there’s a patient who really leaves a mark on you. I recently had a patient like that. He was living 3,000 miles away in Ireland and had seen one of my daily e-newsletters. Right after reading it, he made an appointment, booked a flight and came to my clinic in South Florida. I’ll call him K.O. About 10 years ago, K.O. was diagnosed with dangerously high blood sugar, type 2 diabetes and out-of-control blood pressure. He was 50 years old and taking 10 prescriptions a day. His kidneys were failing him and he was on the short list for a kid...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Nutrition blood sugar carbs diabetes energy stem cells Syndrome Zero Source Type: news
Condition:   Type 2 Diabetes Mellitus Interventions:   Drug: SAR425899;   Drug: [68Ga] Ga-DO3A-VS-Cys40-Tuna-2 (glucagon receptor tracer);   Drug: [68Ga] Ga-DO3A-VS-Cys40-Exendin-4 (GLP-1 receptor tracer) Sponsor:   Sanofi Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Type 2 Diabetes Mellitus Interventions:   Drug: Sotagliflozin (SAR439954);   Drug: Empagliflozin;   Drug: Placebo Sponsor:   Sanofi Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Type 2 Diabetes Mellitus Interventions:   Drug: SAR425899;   Drug: [68Ga] Ga-DO3A-VS-Cys40-Tuna-2 (glucagon receptor tracer);   Drug: [68Ga] Ga-DO3A-VS-Cys40-Exendin-4 (GLP-1 receptor tracer) Sponsor:   Sanofi Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusion: The present study demonstrates that the SNP-44 polymorphism is associated with T2DM susceptibility and contributes to the risk of T2DM. PMID: 29151334 [PubMed]
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
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