Snoring link to Alzheimer ’s disease unproven
Conclusion This relatively large cross-sectional analysis has found a link between certain measures of breathing problems during sleep and poorer cognitive function in middle-aged to older adults. The strengths of this study include its size and use of a prospective sleep study to assess whether people had sleep apnoea or other problems with breathing during sleep. The use of standard cognitive tests is also a strength. However, the study does have its limitations: The study did have mixed findings – while certain measures of problems with breathing during sleep (e.g. oxygen levels) were associated with cognitive outcomes, others (e.g. Apnea-Hypopnea Index) were not. This suggests that findings are not conclusive. In addition, previous studies have also had mixed results. This suggests that a systematic review which brings together all of the available evidence on this question would be helpful to assess whether, on balance, the research suggests a true link. It's not possible from this type of cross-sectional analysis to prove that breathing problems during sleep cause the differences in brain function seen. This is largely because it's not possible to establish whether participants only developed problems with brain function after they experienced sleep breathing problems. It's also difficult to be sure that the effect of all potential confounders has been removed. The study measured brain function at one time point and did not assess whether people ha...
Conclusion: These findings suggest that L‐carnosine may induce browning of adipose tissue through irisin stimulation, a phenomenon that could be related to its antioxidant, anti‐inflammatory and anti‐obesity effect. This article is protected by copyright. All rights reserved
Conclusion: The knowledge about hypertension among majority of patients was reasonable. But they were unaware of their disease status. The drug compliance among them was poor. Forgetfulness and interruptions of daily routine were common reasons attributed for nonadherence. PMID: 29230325 [PubMed]
Older adults who develop hearing loss may more likely to experience dementia and cognitive decline than their counterparts without hearing problems, a research review suggests.Reuters Health Information
Authors: Inokuchi M, Matsuo N, I Takayama J, Hasegawa T Abstract Obesity in children is a serious public health problem in Japan. However, the prevalence of central fatness has not been well determined in Japanese youth. We studied the relationship between body mass index (BMI) and waist circumference (WC) using line of equality analysis in 5,787 boys and 4,639 girls aged 6 to 17 years who participated in the 1992-1994 national survey on body sizes. WC was measured at the level of maximum waist narrowing in girls (WC1) and at the level of the top of iliac crest in boys (WC2). Using the 1978-1981 national survey dat...
CONCLUSIONS: A parent-focused primary prevention intervention based on MI delivered within child health services did not result in effects at 1-year follow-up. The results were in line with those obtained at post-assessment and indicated no late onset of effect. Further studies exploring individual and contextual factors influencing the outcome are called for. PMID: 29232526 [PubMed - as supplied by publisher]
This article is protected by copyright. All rights reserved
New J. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7NJ04008C, PaperSajjad Mohebbi, Parvin Askari A new nanohybrid catalyst by covalent linking of tetraacetate porphyrin cobalt(II) complex to TiO2/BiVO4 nanocomposite was synthesised and its photocatalytic efficiency toward alcohol oxidation under visible light irradiation monitored by... The content of this RSS Feed (c) The Royal Society of Chemistry
Chem. Commun., 2017, Accepted Manuscript DOI: 10.1039/C7CC08548F, CommunicationLouis Lancaster, David P Hickey, Matthew S. Sigman, Shelley Minteer, Ian Wheeldon This work combines the thermostable alcohol dehydrogenase D (AdhD) from Pyrococcus furiosus and the organic electrocatalyst TEMPO to create a bifunctional catalyst that selectively oxidizes primary and secondary alcohols. The... The content of this RSS Feed (c) The Royal Society of Chemistry
Authors: Chen YW, Camp PG, Coxson HO, Road JD, Guenette JA, Hunt MA, Reid WD Abstract In addition to dyspnea and fatigue, pain is a prevalent symptom in chronic obstructive pulmonary disease (COPD). Understanding the relative prevalence, magnitude, and interference with aspects of daily living of these symptoms can improve COPD management. Therefore, the purposes of this study were to: (1) compare the prevalence and magnitude of dyspnea, fatigue, and pain and how each limits aspects of daily living; (2) determine the association between pain and the other two symptoms; and (3) assess the impact of these symptoms on...
Authors: Huang H, Shetty S, Bauer E, Lang K Abstract OBJECTIVE: To estimate the proportion of patients with moderate to severe chronic kidney disease (CKD) whose initial DPP4-i dosage was concordant with prescribing information (label) recommendations in the United States. METHODS: Adult patients with T2DM who initiated a DPP4-i (linagliptin, sitagliptin, saxagliptin) between Jan 1, 2011 and Jun 30, 2014 were identified using electronic medical records and administrative claims, with index date being the date of first observed DPP4-i treatment. Patients were required to have CKD Stage 3b, 4 or 5 (eGFR value
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