Snoring link to Alzheimer ’s disease unproven
Conclusion This relatively large cross-sectional analysis has found a link between certain measures of breathing problems during sleep and poorer cognitive function in middle-aged to older adults. The strengths of this study include its size and use of a prospective sleep study to assess whether people had sleep apnoea or other problems with breathing during sleep. The use of standard cognitive tests is also a strength. However, the study does have its limitations: The study did have mixed findings – while certain measures of problems with breathing during sleep (e.g. oxygen levels) were associated with cognitive outcomes, others (e.g. Apnea-Hypopnea Index) were not. This suggests that findings are not conclusive. In addition, previous studies have also had mixed results. This suggests that a systematic review which brings together all of the available evidence on this question would be helpful to assess whether, on balance, the research suggests a true link. It's not possible from this type of cross-sectional analysis to prove that breathing problems during sleep cause the differences in brain function seen. This is largely because it's not possible to establish whether participants only developed problems with brain function after they experienced sleep breathing problems. It's also difficult to be sure that the effect of all potential confounders has been removed. The study measured brain function at one time point and did not assess whether people ha...
Authors: Kalayinia S, Goodarzynejad H, Maleki M, Mahdieh N Abstract The Human Genome Project (HGP), as the primary sequencing of the human genome, lasted more than one decade to be completed using the traditional Sanger's method. At present, next-generation sequencing (NGS) technology could provide the genome sequence data in hours. NGS has also decreased the expense of sequencing; therefore, nowadays it is possible to carry out both whole-genome (WGS) and whole-exome sequencing (WES) for the variations detection in patients with rare genetic diseases as well as complex disorders such as common cardiovascular disea...
DEMENTIA and neurological diseases could be prevented by eating more honey.
Org. Biomol. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7OB02299A, PaperDiya Alsafadi, Safaa Alsalman, Francesca Paradisi Enzymatic synthesis of enantiopure aromatic secondary alcohols (including substituted, hetero-aromatic and bicyclic structures) were carried out using the halophilic alcohol dehydrogenase ADH2 fromHaloferax volcanii (HvADH2). This enzyme showed an... The content of this RSS Feed (c) The Royal Society of Chemistry
CONCLUSIONS: Although differences exist between the gut microbiota of obese and NW children, we detected highly individualized responses of the gut microbiota of obese children over time and following weight loss. PMID: 29028448 [PubMed - as supplied by publisher]
Conclusion In this PMS, the safety and efficacy profiles of canagliflozin in elderly patients with T2DM were obtained in the clinical settings in Japan, and the drug was well tolerated and effective in improving glycemic control. PMID: 29025285 [PubMed - as supplied by publisher]
CONCLUSION: Early recognition and timely evacuation of spinal abscesses minimized neurological morbidity and potential mortality. PMID: 29026676 [PubMed]
CONCLUSIONS: Three days after the surgery, magnetic resonance imaging demonstrated a gross total resection and adequate third ventriculostomy flow. One year after the surgery, the patient was asymptomatic. Neuroendoscopy has evolved towards minimally invasiveness, and in selected cases is an equally effective surgical approach to ventricular lesions. It provides minimal cerebral cortex disruption and vascular manipulation. PMID: 29026673 [PubMed]
CONCLUSION: In light of recent studies, lasting bilateral mydriasis may not always be considered a decisive factor for non-escalation of treatment, as variability among TBI patients and outcomes has been demonstrated. Wide decompressive craniectomy is viable for controlling refractory intracranial hypertension in hemodynamically stable patients. PMID: 29026665 [PubMed]
CONCLUSIONS: We believe that bilateral MVD is the best approach in cases of BHFS. PMID: 29026661 [PubMed]
BACKGROUND: Anger and depressive ruminations have recently received empirical attention as processes related to borderline personality disorder (BPD). The Emotional Cascade Model (Selby, Anestis,&Joiner, 2008) suggests that negative affect (such as anger...
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