Alcohol 'a direct cause of seven types of cancer'

Conclusion This narrative review aimed to summarise data from published biological and epidemiological research to discuss the strength of evidence that alcohol causes cancer. The author gives their main finding as a link between alcohol consumption and cancer at seven sites, and also that the highest risks seem to be associated with heavier drinking. However, they state there's no "safe" drinking threshold and that low to moderate consumption still contributes to a significant number of cancer cases. The biggest limitation of this review is that it doesn't appear to be systematic. The author provided no methods for how they identified and appraised the research they drew on. Despite referencing a number of large studies and reviews, this study and its conclusions have to be considered largely the opinion of the author following their appraisal of the evidence. We don't know whether the review has considered all research relevant to the topic and is able to reliably quantify the risks of cancer – overall or at specific sites – associated with alcohol consumption. An additional limitation to keep in mind is that this data mainly appeared to be from observational studies. These cannot prove cause and effect. The individual studies will likely have varied considerably in the additional health and lifestyle factors they took account of when looking at the links with alcohol. For example, smoking, diet and physical activity are all factors likely to be asso...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Lifestyle/exercise Source Type: news

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BONE cancer symptoms include aching within the bones, which can be mistaken for arthritis. However, there are also three other symptoms, according to the NHS.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
A recent update of the Italian Road Traffic Law (RTL 41/2016), established severe penal sanctions when drivers, driving under the influence of alcohol (DUI) or drugs (DUID), are involved in road accident that results in death or injuries. A study was carri...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
A recent study followed individuals who had undergone obesity surgery. They found that the procedure significantly reduced their risk of skin cancer.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Melanoma / Skin Cancer Source Type: news
Conclusions: Dosages of 450 mg/d of pregabalin and 1600 mg/d of gabapentin are not significantly superior to placebo in controlling opiate withdrawal symptoms.
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Conclusions: In its present form, this method of data collection was not feasible within these AoD residential services. Greater resources are likely required to improve the utility and acceptability of this method.
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Conclusions: Community support, reducing the social stigma of addiction, building addiction treatment centers for women, informing drug abusers and their families about available health centers, and encouraging drug addicts’ families to participate in Nar-Anon meetings improves their enduring commitment to long-term and unwavering support for the patient through the course of cessation.
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Conclusions: There is a need to enhance educational efforts to improve all clinicians' understanding of alcohol use disorders. The various stakeholders involved should collaborate closely to improve the quality of care rendered to these patients.
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Conclusion: High self-esteem has been effective in improving locus of control and decreasing psychological disorders, and it can be considered the optimal treatment method in psychology.
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Tramadol dependence is a public health problem in Egypt. We aimed to determine the sociodemographic and clinical characteristics of tramadol abuse among Egyptians, the frequency and degrees of insomnia among tramadol abusers, and the relationship between the associated insomnia with sociodemographic and clinical characteristics. Included in this study were 400 subjects (mean age, 30.72±9.61 y) who were tramadol dependent. The subjects were assessed using Structured Clinical Interviewing using DSM-IV (SCID-I), Severity of Dependence Scale (SDS), and Insomnia Severity Index. We found that the mean age at onset ...
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Abstract Several microRNAs (miRNAs) have been reported as oncogenes or tumor suppressors in many cancers, including gastric cancer (GC). However, the role and molecular mechanism of miR-3129 in GC is largely unknown. We aimed to explore the function and the underlying molecular mechanism of miR-3129 in GC. Cancer tissues and corresponding adjacent tissues were collected from 50 patients with GC, and the expression of miR-3129 was detected by RT-qPCR. The expression of miR-3129 and pRb in human GC cell line SCG7091 was altered by transient transfection. Thereafter, MTT and flow cytometry assays were used to analyze...
Source: Braz J Med Biol Res - Category: Research Authors: Tags: Braz J Med Biol Res Source Type: research
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