What to Expect When You're... Still Not Expecting

IVF Isn't About the Journey, It's About the Destination While some women may share their birth stories, I wanted to share our fertility story. Translating my mind's weavings into words on paper has helped me weather numerous storms, but throughout 2015 -- a year marred by a lot of heartbreak and too many hormonal injections -- when I've needed this kind of therapy the most, I maintained silence on a subject that hit me like a piece of fallen scaffolding. Instead, I relied heavily on the physical support of my husband, family and friends, all for whom I am extremely grateful. With each setback along this grueling and at times never-ending journey, I would begin the story over and over again in my head, but I never got around to completing it. Until now. *** After a year and a half of trying to get pregnant the old-fashioned way, which is to say without downloading ovulation apps and marking red Ps on the calendar every month, and just hoping it would take a few romantic evenings at home or on vacation with my husband, we consulted a local OB-GYN about our dilemma. She prescribed a few months of charting everything from my morning temperature to the location of my cervix. That didn't work. She then prescribed three months of Clomid -- a drug that helps women ovulate more regularly, which in turn can help you track when to have sex more accurately. My cycles were anywhere between 28 and 40 days, so I hoped this would be the wonder drug we needed to get pregnant. It was n...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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A patient referred for prenatal diagnostics, after first-trimester ultrasound due to a previous child with Leber congenital amaurosis, was suggestive of a Meckel syndrome-like phenotype. Fetal autopsy confirmed the multiple anomalies, and whole-exome sequencing of the fetal DNA identified a pathogenic variant in theRPGRIP1 gene, previously identified in the elder sibling, and a variant causative of Meckel syndrome 1 in theMKS1gene. Reporting theMKS1 mutation, which was present in heterozygous state in the elder sibling, as a secondary finding would have enabled the parents to be tested for carrier status of the same varian...
Source: Molecular Syndromology - Category: Molecular Biology Source Type: research
The Public Health England information campaign will launch in six weeks' time. There will be adverts on TV and social media designed to increase take-up of smear tests and screening.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
ConclusionsA higher percentage of quadriceps muscle and better muscle quality (lower EI) was associated with better function. Age and exercise levels influenced function. Ultrasound may provide
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
Conclusion High caspase-3 and AIF expressions and low Bcl-2 expression were risk factors for term PROM. Caspase-dependent and independent pathways of apoptosis were involved in the mechanism of PROM in term pregnancy.
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Conclusion The pHua and the BDua are predictors of adverse neonatal outcome, and UCBGA is a useful tool for screening newborns at risk. Universal UCBGA should be considered for all deliveries, as it is an accurate screening test for neonatal hypoxia.Resumo Objetivo Avaliar se o pH da art éria umbilical (pHua) ≤ 7,00 e o d éficit de bases da artéria umbilical (BDua) ≥ 12,00 mmol/L s ão preditores de desfechos neonatais adversos. Métodos Estudo observacional, longitudinal e retrospectivo, realizado no Serviço de Ginecolocgia e Obstetrícia do Centro Hospitalar Tondela Vis...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Abstract Objective To describe caffeine consumption during pregnancy and its association with low birth weight (LBW) and preterm birth in the birth cohort of Ribeir ão Preto, state of São Paulo, Brazil, in 2010. Methods Cohort study, with descriptive and analytical approach. Data included 7,607 women and their newborns in Ribeirão Preto, state of São Paulo, Brazil. The women answered standardized questionnaires about reproductive health, prenatal care, li fe habits, sociodemographic conditions, and information about coffee intake. The independent variable was high caffeine consumption ( ≥ 300...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Conclusion Plasma TIMP-4 levels were not altered at 20 to 25 weeks of gestation, before the manifestation of clinical symptoms; therefore, they are not good predictors of the development of preeclampsia.Resumo Objetivo Avaliar se o n ível de inibidor tecidual de metaloproteinases tipo-4 (TIMP-4, na sigla em inglês) circulante no período entre 20 e 25 semanas de gestação é um preditor de preeclâmpsia. Métodos Foi realizado um estudo caso-controle aninhado em uma coorte de estudo prospectivo em Ribeirão Preto, São Paul o, Brasil. De 1.400 mulheres grá...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Conclusion Both FSH isoforms induced similar depolarization patterns, but β -follitropin presented a faster response. A better understanding of the differences of the effects of FSH isoforms on cell membrane potential shall contribute to improve the use of gonadotrophins in fertility treatments.Resumo Objetivo O objetivo do presente estudo foi fornecer uma melhor compreens ão da ação específica de duas isoformas de hormônio folículo estimulante (FSH, sigla em inglês) ( β -folitropina e FSH ovino) no potencial de membrana de c élulas do cumulus oophorus humanas...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Conclusion Infertilewomenhadno increased riskof sexual dysfunction relativetocontrols. Anxiety and depression increased the risk of sexual dysfunction in the studied population.Resumo Objetivo Avaliar a fun ção sexual, ansiedade e depressão de mulheres inférteis em relação a um grupo controle. Métodos Mulheres inférteis (grupo infértil, GI) em idade reprodutiva foram convidadas a participar deste estudo. Um grupo controle (GC) de mulheres foi recrutado da população geral da mesma cidade. A função sexual foi avaliada pelo Índic...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
We present the case of a 23-year-old pregnant woman with a history of Langerhans cell histiocytosis of the mandible submitted to surgery and chemotherapy when she was 10 years old, with diagnosis of ITP since then. At 28 weeks of gestation, she presented with petechiae, epistaxis, and gingival bleeding, with a platelet count of 3 x 109/L and positive IgG antiplatelet antibodies test. At a multidisciplinary discussion, it was decided to delay a cesarean section, due to the absence of fetal distress and to the high risk of morbidity for the patient. Many therapies were attempted without success. The IgG produced a slight and...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
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