HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis

CONCLUSIONS: Statins reduce death and major cardiovascular events by about 20% and probably make no difference to stroke or kidney failure in people with CKD not requiring dialysis. However, due to limited reporting, the effect of statins on elevated creatinine kinase or rhabdomyolysis is unclear. Statins have an important role in the primary prevention of cardiovascular events and death in people who have CKD and do not require dialysis. Editorial note: This is a living systematic review. We will search for new evidence every three months and update the review when we identify relevant new evidence. Please refer to the Cochrane Database of Systematic Reviews for the current status of this review.PMID:38018702 | PMC:PMC10685396 | DOI:10.1002/14651858.CD007784.pub3
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Source Type: research