Comparing Neuromuscular Blockade Measurement Between Upper Arm (TOF Cuff ®) and Eyelid (TOF Scan®) Using Mivacurium during General Anesthesia
CONCLUSIONS When measurement on the limb is not possible, TOF-Scan on the eyelid can be an alternative for TOF-Cuff on the upper arm, if the time to relaxation is multiplied by at least 8, which is enough for 90% of patients.PMID:38693676 | DOI:10.12659/MSM.943630 (Source: Medical Science Monitor)
Source: Medical Science Monitor - May 2, 2024 Category: Research Authors: Pawe ł Radkowski Jakub Ru ść Mariusz K ęska Klaudia Sztaba Source Type: research
Comparison of Effects of Sugammadex and Neostigmine on Postoperative Neuromuscular Blockade Recovery in Patients with Interstitial Lung Diseases Undergoing Transbronchial Cryobiopsy: A Randomized Trial
CONCLUSIONS Sugammadex is more effective than neostigmine in reversing the muscle-relaxant effect of rocuronium bromide in patients with ILDs.PMID:38689479 | DOI:10.12659/MSM.942773 (Source: Medical Science Monitor)
Source: Medical Science Monitor - May 1, 2024 Category: Research Authors: Liya Lu Xiaobo Chen Shiyue Li Yanyi Cen Source Type: research
Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) - Lifileucel (Amtagvi)
Med Sci Monit. 2024 May 1;30:e944927. doi: 10.12659/MSM.944927.ABSTRACTOn February 16, 2024, the US Food and Drug Agency (FDA) granted accelerated approval to lifileucel (Amtagvi), an adoptive immune cell therapy with autologous ex vivo-expanded tumor-infiltrating lymphocytes (TILs) for adult patients with advanced or unresectable melanoma progressing after treatment with immune checkpoint inhibitors and, if BRAF V600 mutation-positive, BRAF/MEK inhibitors. The clinical studies supporting this regulatory approval have highlighted the complexity of the treatment manufacturing process and the requirements for patient selecti...
Source: Medical Science Monitor - May 1, 2024 Category: Research Authors: Dinah V Parums Source Type: research
Comparison of Effects of Sugammadex and Neostigmine on Postoperative Neuromuscular Blockade Recovery in Patients with Interstitial Lung Diseases Undergoing Transbronchial Cryobiopsy: A Randomized Trial
CONCLUSIONS Sugammadex is more effective than neostigmine in reversing the muscle-relaxant effect of rocuronium bromide in patients with ILDs.PMID:38689479 | DOI:10.12659/MSM.942773 (Source: Medical Science Monitor)
Source: Medical Science Monitor - May 1, 2024 Category: Research Authors: Liya Lu Xiaobo Chen Shiyue Li Yanyi Cen Source Type: research
Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) - Lifileucel (Amtagvi)
Med Sci Monit. 2024 May 1;30:e944927. doi: 10.12659/MSM.944927.ABSTRACTOn February 16, 2024, the US Food and Drug Agency (FDA) granted accelerated approval to lifileucel (Amtagvi), an adoptive immune cell therapy with autologous ex vivo-expanded tumor-infiltrating lymphocytes (TILs) for adult patients with advanced or unresectable melanoma progressing after treatment with immune checkpoint inhibitors and, if BRAF V600 mutation-positive, BRAF/MEK inhibitors. The clinical studies supporting this regulatory approval have highlighted the complexity of the treatment manufacturing process and the requirements for patient selecti...
Source: Medical Science Monitor - May 1, 2024 Category: Research Authors: Dinah V Parums Source Type: research
Evaluation of Retentive Strength of 50 Endodontically-Treated Single-Rooted Mandibular Second Premolars Restored with Cast Post Cores Using 5 Common Luting (Cement) Agents
CONCLUSIONS All investigated cements provided optimal retentive strengths, with wide differences between them. Resin cements should be used when CPC removal is not anticipated, while polycarboxylate or zinc phosphate should be used if CPC removal is anticipated.PMID:38685688 | DOI:10.12659/MSM.944110 (Source: Medical Science Monitor)
Source: Medical Science Monitor - April 30, 2024 Category: Research Authors: Monika Singh Soundarya Singh Lakshya Kumar Khurshid A Mattoo Imran Khalid Mohammad Zahir Kota Samuel Ebele Udeabor Fawaz Abdul Hamid Baig Mohammad Ishfaq Mohammed Ibrahim Sulphi Abdul Basheer Source Type: research
Comparative Analysis of Open and Closed Sphincterotomy for the Treatment of Chronic Anal Fissure: Safety and Efficacy Evaluation
CONCLUSIONS Comparing the 2 methods used in chronic anal fissure surgery, and considering the recurrence and risk of incontinence, the most feared outcome by the patient and surgeon, open LIS stands out as a superior technique, especially in young male patients.PMID:38679898 | DOI:10.12659/MSM.944127 (Source: Medical Science Monitor)
Source: Medical Science Monitor - April 29, 2024 Category: Research Authors: Mehmet Zafer Sabuncuoglu Isa Sozen İsmail Zihni Girayhan Celik Bilal Turan Serdar Acar İsa Karaca Demet Gunduz Source Type: research
Modification of Experimental Model of Necrotizing Enterocolitis (NEC) in Rat Pups by Single Exposure to Hypothermia and Hypoxia and Impact of Mother's Milk on Incidence of Disease
CONCLUSIONS The modified experimental NEC model based on formula feeding and single exposure to hypothermia and hypoxia was assessed statistically and histologically. In this model, mother's milk had a protective effect against necrotizing enterocolitis.PMID:38678319 | DOI:10.12659/MSM.943443 (Source: Medical Science Monitor)
Source: Medical Science Monitor - April 28, 2024 Category: Research Authors: Marek Wolski Source Type: research
Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourth-Year PharmD Undergraduates from Riyadh, Saudi Arabia
CONCLUSIONS This study indicated that half of undergraduates were aware of CTs, were knowledgeable, and showed positive attitudes. Furthermore, the study identified potential misunderstandings about the benefits of CTs.PMID:38676293 | DOI:10.12659/MSM.943468 (Source: Medical Science Monitor)
Source: Medical Science Monitor - April 27, 2024 Category: Research Authors: Wajid Syed Mahmood Basil A Al-Rawi Adel Bashatah Source Type: research
The Role of Copper-Induced M2 Macrophage Polarization in Protecting Cartilage Matrix in Osteoarthritis
CONCLUSIONS These results suggest that Cu-BGC induced macrophage polarization into an M2 type anti-inflammatory phenotype, and inhibition of immune injury response may play a role in delaying cartilage matrix damage in osteoarthritis.PMID:38664941 | DOI:10.12659/MSM.943738 (Source: Medical Science Monitor)
Source: Medical Science Monitor - April 26, 2024 Category: Research Authors: Dawei Geng Rongcai Lin Peiran Wei Cheng Tang Yan Xu Liming Wang Source Type: research
Evaluation of Foot Structure in Preschool Children Based on Body Mass
CONCLUSIONS No correlation was observed between high BMI and the occurrence of anomalies in foot structure. A relationship was identified between muscle mass and foot structure.PMID:38659197 | DOI:10.12659/MSM.943765 (Source: Medical Science Monitor)
Source: Medical Science Monitor - April 25, 2024 Category: Research Authors: Aleksandra Kopaczy ńska Alicja Bober Agnieszka Puk Agnieszka Chwa łczyńska Source Type: research
