Atypical isolated cataplexy: two case reports and a mini-review
We describe two cases of isolated cataplexy with different outcomes, highlighting the diagnostic and prognostic challenges. There is conflicting literature as to whether it is a legitimate standalone diagnosis or an early warning sign of narcolepsy. Our cases do not fit with current diagnostic criteria for narcolepsy, yet still share some clinical or laboratory features. These ambiguous cases question what the mechanistic relationship between narcolepsy and cataplexy may be.PMID:38678310 | DOI:10.1080/13554794.2024.2347606 (Source: Neurocase)
Source: Neurocase - April 27, 2024 Category: Neurology Authors: Vinay Mandagere Dane Rayment Source Type: research
Wastewater based epidemiology as a public health resource in low- and middle-income settings
Environ Pollut. 2024 Apr 25:124045. doi: 10.1016/j.envpol.2024.124045. Online ahead of print.ABSTRACTIn the face of emerging and re-emerging diseases, novel and innovative approaches to population scale surveillance are necessary for the early detection and quantification of pathogens. The last decade has seen the rapid development of wastewater and environmental surveillance (WES) to address public health challenges, which has led to establishment of wastewater-based epidemiology (WBE) approaches being deployed to monitor a range of health hazards. WBE exploits the fact that excretions and secretions from urine, and from ...
Source: Environmental Pollution - April 27, 2024 Category: Environmental Health Authors: K A Hamilton M J Wade K G Barnes R A Street S Paterson Source Type: research
Atypical isolated cataplexy: two case reports and a mini-review
We describe two cases of isolated cataplexy with different outcomes, highlighting the diagnostic and prognostic challenges. There is conflicting literature as to whether it is a legitimate standalone diagnosis or an early warning sign of narcolepsy. Our cases do not fit with current diagnostic criteria for narcolepsy, yet still share some clinical or laboratory features. These ambiguous cases question what the mechanistic relationship between narcolepsy and cataplexy may be.PMID:38678310 | DOI:10.1080/13554794.2024.2347606 (Source: Neurocase)
Source: Neurocase - April 27, 2024 Category: Neurology Authors: Vinay Mandagere Dane Rayment Source Type: research
Hazard warning modalities and timing thresholds for older drivers with impaired vision
CONCLUSIONS: While early warnings improved hazard responses and reduced collisions for ICS participants, late warnings did not, resulting in high collision rates. In contrast, both early and late warnings were helpful for NV drivers. Non-directional-tactile warnings were the most effective in reducing collisions. The findings provide insights relevant to the development of hazard warnings tailored for drivers with impaired vision.PMID:38669900 | DOI:10.1016/j.aap.2024.107599 (Source: Accident; Analysis and Prevention.)
Source: Accident; Analysis and Prevention. - April 26, 2024 Category: Accident Prevention Authors: Jing Xu Alex R Bowers Source Type: research
The application value and improved warning criterion of D-wave monitoring in intramedullary spinal cord tumor surgery
The primary treatment method for intramedullary spinal cord tumor (IMSCT) is surgical resection, but this procedure carries a significant risk of neurological damage. Intraoperative neurophysiological monitoring (IONM) has become a necessary adjunctive tool for IMSCT resection. (Source: The Spine Journal)
Source: The Spine Journal - April 26, 2024 Category: Orthopaedics Authors: Ke Li, Xiaorong Tao, Jiajia Liu, Jun Yang, Jiawei Shi, Xiao Wu, Wenqing Jia, Xing Fan, Hui Qiao Tags: Clinical Study Source Type: research
Predicting haemorrhagic transformation through serum biochemical indices for patients after endovascular treatment: a retrospective study
CONCLUSIONS: The levels of serum biochemical markers were found to show significant changes before and after EVT in ACLVO patients. A combination of demographic data and serum biochemical markers proved to be effective in predicting the occurrence of HT in patients with ACLVO who underwent EVT.PMID:38662104 | DOI:10.5603/pjnns.97759 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - April 25, 2024 Category: Neurology Authors: Fang Wu Qingyuan Wu Qinji Zhou Lina Zhang Fei Yan Yaping Xiao Fanping Meng Lei He Zhenjie Yang Chuyue Wu Source Type: research
FDA Issues Warning About 'Gas Station Heroin'
Am J Nurs. 2024 May 1;124(5):13. doi: 10.1097/01.NAJ.0001016316.12810.5d. Epub 2024 Apr 25.ABSTRACTThe highly addictive dietary supplement mimics opioid effects.PMID:38661686 | DOI:10.1097/01.NAJ.0001016316.12810.5d (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - April 25, 2024 Category: Nursing Authors: Karen Roush Source Type: research
Detecting early-warning biomarkers associated with heart-exosome genetic-signature for acute myocardial infarction: A source-tracking study of exosome
J Cell Mol Med. 2024 Apr;28(8):e18334. doi: 10.1111/jcmm.18334.ABSTRACTThe genetic information of plasma total-exosomes originating from tissues have already proven useful to assess the severity of coronary artery diseases (CAD). However, plasma total-exosomes include multiple sub-populations secreted by various tissues. Only analysing the genetic information of plasma total-exosomes is perturbed by exosomes derived from other organs except the heart. We aim to detect early-warning biomarkers associated with heart-exosome genetic-signatures for acute myocardial infarction (AMI) by a source-tracking analysis of plasma exoso...
Source: J Cell Mol Med - April 25, 2024 Category: Molecular Biology Authors: Xiaojun Jin Weifeng Xu Qiaoping Wu Chen Huang Yongfei Song Jiangfang Lian Source Type: research
"Inherently Limited by Our Imaginations": Health Anxieties, Politics, and the History of the Climate Crisis
Perspect Biol Med. 2024;67(1):31-62. doi: 10.1353/pbm.2024.a919709.ABSTRACTAs global warming became a cause of concern in the 1980s, researchers and climate activists initially paid little attention to the possible health effects of a warmer world. This changed quickly between 1985 and 1989, when scientists working on contracts with the US Department of Energy and the Environmental Protection Agency extrapolated from existing knowledge about the impact of weather on health to speculate about how global warming would impact health. However, they downplayed the impact of their contributions by highlighting the uncertainty in...
Source: Perspectives in Biology and Medicine - April 25, 2024 Category: Medical Ethics Authors: David Shumway Jones Source Type: research
Detecting early-warning biomarkers associated with heart-exosome genetic-signature for acute myocardial infarction: A source-tracking study of exosome
J Cell Mol Med. 2024 Apr;28(8):e18334. doi: 10.1111/jcmm.18334.ABSTRACTThe genetic information of plasma total-exosomes originating from tissues have already proven useful to assess the severity of coronary artery diseases (CAD). However, plasma total-exosomes include multiple sub-populations secreted by various tissues. Only analysing the genetic information of plasma total-exosomes is perturbed by exosomes derived from other organs except the heart. We aim to detect early-warning biomarkers associated with heart-exosome genetic-signatures for acute myocardial infarction (AMI) by a source-tracking analysis of plasma exoso...
Source: Molecular Medicine - April 25, 2024 Category: Molecular Biology Authors: Xiaojun Jin Weifeng Xu Qiaoping Wu Chen Huang Yongfei Song Jiangfang Lian Source Type: research
Heat and Cardiovascular Mortality: An Epidemiological Perspective
Circ Res. 2024 Apr 26;134(9):1098-1112. doi: 10.1161/CIRCRESAHA.123.323615. Epub 2024 Apr 25.ABSTRACTAs global temperatures rise, extreme heat events are projected to become more frequent and intense. Extreme heat causes a wide range of health effects, including an overall increase in morbidity and mortality. It is important to note that while there is sufficient epidemiological evidence for heat-related increases in all-cause mortality, evidence on the association between heat and cause-specific deaths such as cardiovascular disease (CVD) mortality (and its more specific causes) is limited, with inconsistent findings. Exi...
Source: Circulation Research - April 25, 2024 Category: Cardiology Authors: Nidhi Singh Ashtyn Tracy Areal Susanne Breitner Siqi Zhang Stefan Agewall Tamara Schikowski Alexandra Schneider Source Type: research
Predicting haemorrhagic transformation through serum biochemical indices for patients after endovascular treatment: a retrospective study
CONCLUSIONS: The levels of serum biochemical markers were found to show significant changes before and after EVT in ACLVO patients. A combination of demographic data and serum biochemical markers proved to be effective in predicting the occurrence of HT in patients with ACLVO who underwent EVT.PMID:38662104 | DOI:10.5603/pjnns.97759 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - April 25, 2024 Category: Neurology Authors: Fang Wu Qingyuan Wu Qinji Zhou Lina Zhang Fei Yan Yaping Xiao Fanping Meng Lei He Zhenjie Yang Chuyue Wu Source Type: research
FDA Issues Warning About 'Gas Station Heroin'
Am J Nurs. 2024 May 1;124(5):13. doi: 10.1097/01.NAJ.0001016316.12810.5d. Epub 2024 Apr 25.ABSTRACTThe highly addictive dietary supplement mimics opioid effects.PMID:38661686 | DOI:10.1097/01.NAJ.0001016316.12810.5d (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - April 25, 2024 Category: Nursing Authors: Karen Roush Source Type: research
Detecting early-warning biomarkers associated with heart-exosome genetic-signature for acute myocardial infarction: A source-tracking study of exosome
J Cell Mol Med. 2024 Apr;28(8):e18334. doi: 10.1111/jcmm.18334.ABSTRACTThe genetic information of plasma total-exosomes originating from tissues have already proven useful to assess the severity of coronary artery diseases (CAD). However, plasma total-exosomes include multiple sub-populations secreted by various tissues. Only analysing the genetic information of plasma total-exosomes is perturbed by exosomes derived from other organs except the heart. We aim to detect early-warning biomarkers associated with heart-exosome genetic-signatures for acute myocardial infarction (AMI) by a source-tracking analysis of plasma exoso...
Source: J Cell Mol Med - April 25, 2024 Category: Molecular Biology Authors: Xiaojun Jin Weifeng Xu Qiaoping Wu Chen Huang Yongfei Song Jiangfang Lian Source Type: research
"Inherently Limited by Our Imaginations": Health Anxieties, Politics, and the History of the Climate Crisis
Perspect Biol Med. 2024;67(1):31-62. doi: 10.1353/pbm.2024.a919709.ABSTRACTAs global warming became a cause of concern in the 1980s, researchers and climate activists initially paid little attention to the possible health effects of a warmer world. This changed quickly between 1985 and 1989, when scientists working on contracts with the US Department of Energy and the Environmental Protection Agency extrapolated from existing knowledge about the impact of weather on health to speculate about how global warming would impact health. However, they downplayed the impact of their contributions by highlighting the uncertainty in...
Source: Perspectives in Biology and Medicine - April 25, 2024 Category: Medical Ethics Authors: David Shumway Jones Source Type: research
