Warnings Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Development of an enhanced scoring system to predict ICU readmission or in-hospital death within 24 hours using routine patient data from two NHS Foundation Trusts
Conclusions We showed that a scoring system incorporating data from a patient’s stay in the ICU has better performance than commonly used EWS systems based on vital signs alone. Trial registration number ISRCTN32008295. (Source: BMJ Open)
Source: BMJ Open - April 12, 2024 Category: General Medicine Authors: Pimentel, M. A. F., Johnson, A., Darbyshire, J. L., Tarassenko, L., Clifton, D. A., Walden, A., Rechner, I., Watkinson, P. J., Young, J. D. Tags: Open access, Intensive care Source Type: research

Predictive performance of NEWS and qSOFA in immunocompromised sepsis patients at the emergency department
ConclusionIn contrast to NEWS, qSOFA underestimates the risk of adverse outcome in patients using high-dose glucocorticoids. As a clinical consequence, to adequately assess the severity of illness among immunocompromised patients, health care professionals should best use the NEWS. (Source: Infection)
Source: Infection - April 12, 2024 Category: Infectious Diseases Source Type: research

Effect of Regdanvimab on Mortality in Patients Infected with SARS-CoV-2 Delta Variants: A Propensity Score-Matched Cohort Study
ConclusionsWe showed that regdanvimab reduced the exacerbation rates of conditions and mortality in patients with the COVID-19 delta variant infection. Thus, it is recommended to streamline the drug approval system during epidemics of new variant viruses to improve the availability and usage of therapeutics for patients. To facilitate this, relevant institutional support is required. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - April 12, 2024 Category: Infectious Diseases Source Type: research

News at a glance: Jailed conservationists freed, physics titan dies, and diversity in anatomical illustrations
ASTRONOMY Scientists flock to the eclipse Tens of millions in North America turned their specially protected eyes to the skies on 8 April for several minutes of darkness when the Moon blocked the disk of the Sun, casting a shadow across Mexico, 15 U.S. states, and Canada. Researchers and citizen scientists seized the opportunity to study the corona—the wispy, outer layer of the Sun’s atmosphere—from the ground and in eclipse-chasing aircraft. They expected to see loops of plasma and other solar flares because the eclipse coincided with solar maximum, a period of high magnetic activity. Research...
Source: Science of Aging Knowledge Environment - April 11, 2024 Category: Geriatrics Source Type: research

DSCAM-AS1 promotes the development of prostate cancer
ConclusionDSCAM-AS1 is up-regulated in prostate cancer and regulates the progression of prostate cancer cells by targeting miR-338-3p. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 11, 2024 Category: Cancer & Oncology Source Type: research

Learning with an evolving medicine label: how artificial intelligence-based medication recommendation systems must adapt to changing medication labels
Expert Opin Drug Saf. 2024 Apr 10. doi: 10.1080/14740338.2024.2338252. Online ahead of print.ABSTRACTArtificial intelligence or machine learning (AI/ML) based systems can be used to help personalize prescribing decisions for individual patients. These AI/ML clinical decision support systems may provide either specific or more open-ended recommendations for the most appropriate medications to prescribe. These systems must fundamentally relate to the label of the medicines involved. The label of a medicine is an approved guide that indicates how to prescribe the drug in a safe and effective manner. The label for a medicine m...
Source: Expert Opinion on Drug Safety - April 10, 2024 Category: Drugs & Pharmacology Authors: Harriet Aprilia Dickinson Jan Feifel Katoo Muylle Taichi Ochi Enriqueta Vallejo-Yag üe Source Type: research

The 2023 Dengue Outbreak in Bangladesh: Exploring the Epidemiology in Hospitalized Patients
We report that a substantial number of patients developed severe dengue during the epidemic in 2023, and provide detailed clinical-epidemiological profiles of the patients, offering valuable insight into management of dengue cases.PMID:38593789 | DOI:10.4269/ajtmh.23-0806 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 9, 2024 Category: Tropical Medicine Authors: Urby Saraf Anika Muna Islam Fatema E Nur Mou Mrinal Saha Aparna Deb Rubaiya Rahman Tui Joarder Rakeen Manzoor Afroza Jesmin Ayesha Martuja Jannatul Fardous Mohiuddin Sharif Md Abdur Rafi Mohammad Jahid Hasan Source Type: research

The 2023 Dengue Outbreak in Bangladesh: Exploring the Epidemiology in Hospitalized Patients
We report that a substantial number of patients developed severe dengue during the epidemic in 2023, and provide detailed clinical-epidemiological profiles of the patients, offering valuable insight into management of dengue cases.PMID:38593789 | DOI:10.4269/ajtmh.23-0806 (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 9, 2024 Category: Infectious Diseases Authors: Urby Saraf Anika Muna Islam Fatema E Nur Mou Mrinal Saha Aparna Deb Rubaiya Rahman Tui Joarder Rakeen Manzoor Afroza Jesmin Ayesha Martuja Jannatul Fardous Mohiuddin Sharif Md Abdur Rafi Mohammad Jahid Hasan Source Type: research