Topical clindamycin for acne vulgaris: analysis of gastrointestinal events
Conclusions: According to pharmacovigilance data, the rate of GI adverse drug reactions with topical clindamycin-containing products was 0.000045% (64/141,084,533). Results from two retrospective medical record studies of patients with AV indicated that physicians prescribe topical clindamycin equally to patients with or without inflammatory bowel disease history, and that rates of pseudomembranous colitis in these patients were low. In 8 published pivotal clinical trials of topical clindamycin for AV, GI AEs were reported in 1.4% of participants. Limitations include under/inaccurate reporting of AEs or prescription data a...
Source: Journal of Dermatological Treatment - April 3, 2024 Category: Dermatology Authors: Natalia M Pelet Del Toro Andrew Strunk Jashin J Wu Linda Stein Gold James Q Del Rosso Robert T Brodell George Han Source Type: research

SSRI Behavioral Activation, the Boxed Bolded Warning, and Neurodevelopmental Disorders
J Clin Psychiatry. 2024 Apr 2;85(2):24ac15280. doi: 10.4088/JCP.24ac15280.NO ABSTRACTPMID:38569179 | DOI:10.4088/JCP.24ac15280 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - April 3, 2024 Category: Psychiatry Authors: Mayank Gupta Source Type: research

Development and validation of a comprehensive model to predict complications after hepatectomy
CONCLUSIONS: We developed an accurate and practical scoring system based on preoperative and early postoperative data to predict poor outcomes after hepatectomy. Further external validation on larger series could lead to the integration of such a tool in the routine clinical practice to support patients' management and early warning during ICU stay.GRAPHICAL ABSTRACT: https://www.europeanreview.org/wp/wp-content/uploads/Graphical-Abstract-NEW-2.pdf.PMID:38567611 | DOI:10.26355/eurrev_202403_35758 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: R Gaspari F Ardito P C Pafundi A W Avolio P Aceto E Adducci M Pallocchi E Parente L Sollazzi M Antonelli F Giuliante Source Type: research

Topical clindamycin for acne vulgaris: analysis of gastrointestinal events
Conclusions: According to pharmacovigilance data, the rate of GI adverse drug reactions with topical clindamycin-containing products was 0.000045% (64/141,084,533). Results from two retrospective medical record studies of patients with AV indicated that physicians prescribe topical clindamycin equally to patients with or without inflammatory bowel disease history, and that rates of pseudomembranous colitis in these patients were low. In 8 published pivotal clinical trials of topical clindamycin for AV, GI AEs were reported in 1.4% of participants. Limitations include under/inaccurate reporting of AEs or prescription data a...
Source: Journal of Dermatological Treatment - April 3, 2024 Category: Dermatology Authors: Natalia M Pelet Del Toro Andrew Strunk Jashin J Wu Linda Stein Gold James Q Del Rosso Robert T Brodell George Han Source Type: research

SSRI Behavioral Activation, the Boxed Bolded Warning, and Neurodevelopmental Disorders
J Clin Psychiatry. 2024 Apr 2;85(2):24ac15280. doi: 10.4088/JCP.24ac15280.NO ABSTRACTPMID:38569179 | DOI:10.4088/JCP.24ac15280 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - April 3, 2024 Category: Psychiatry Authors: Mayank Gupta Source Type: research

Development and validation of a comprehensive model to predict complications after hepatectomy
CONCLUSIONS: We developed an accurate and practical scoring system based on preoperative and early postoperative data to predict poor outcomes after hepatectomy. Further external validation on larger series could lead to the integration of such a tool in the routine clinical practice to support patients' management and early warning during ICU stay.GRAPHICAL ABSTRACT: https://www.europeanreview.org/wp/wp-content/uploads/Graphical-Abstract-NEW-2.pdf.PMID:38567611 | DOI:10.26355/eurrev_202403_35758 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: R Gaspari F Ardito P C Pafundi A W Avolio P Aceto E Adducci M Pallocchi E Parente L Sollazzi M Antonelli F Giuliante Source Type: research

Topical clindamycin for acne vulgaris: analysis of gastrointestinal events
Conclusions: According to pharmacovigilance data, the rate of GI adverse drug reactions with topical clindamycin-containing products was 0.000045% (64/141,084,533). Results from two retrospective medical record studies of patients with AV indicated that physicians prescribe topical clindamycin equally to patients with or without inflammatory bowel disease history, and that rates of pseudomembranous colitis in these patients were low. In 8 published pivotal clinical trials of topical clindamycin for AV, GI AEs were reported in 1.4% of participants. Limitations include under/inaccurate reporting of AEs or prescription data a...
Source: Journal of Dermatological Treatment - April 3, 2024 Category: Dermatology Authors: Natalia M Pelet Del Toro Andrew Strunk Jashin J Wu Linda Stein Gold James Q Del Rosso Robert T Brodell George Han Source Type: research

SSRI Behavioral Activation, the Boxed Bolded Warning, and Neurodevelopmental Disorders
J Clin Psychiatry. 2024 Apr 2;85(2):24ac15280. doi: 10.4088/JCP.24ac15280.NO ABSTRACTPMID:38569179 | DOI:10.4088/JCP.24ac15280 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - April 3, 2024 Category: Psychiatry Authors: Mayank Gupta Source Type: research

Development and validation of a comprehensive model to predict complications after hepatectomy
CONCLUSIONS: We developed an accurate and practical scoring system based on preoperative and early postoperative data to predict poor outcomes after hepatectomy. Further external validation on larger series could lead to the integration of such a tool in the routine clinical practice to support patients' management and early warning during ICU stay.GRAPHICAL ABSTRACT: https://www.europeanreview.org/wp/wp-content/uploads/Graphical-Abstract-NEW-2.pdf.PMID:38567611 | DOI:10.26355/eurrev_202403_35758 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: R Gaspari F Ardito P C Pafundi A W Avolio P Aceto E Adducci M Pallocchi E Parente L Sollazzi M Antonelli F Giuliante Source Type: research

Topical clindamycin for acne vulgaris: analysis of gastrointestinal events
Conclusions: According to pharmacovigilance data, the rate of GI adverse drug reactions with topical clindamycin-containing products was 0.000045% (64/141,084,533). Results from two retrospective medical record studies of patients with AV indicated that physicians prescribe topical clindamycin equally to patients with or without inflammatory bowel disease history, and that rates of pseudomembranous colitis in these patients were low. In 8 published pivotal clinical trials of topical clindamycin for AV, GI AEs were reported in 1.4% of participants. Limitations include under/inaccurate reporting of AEs or prescription data a...
Source: Journal of Dermatological Treatment - April 3, 2024 Category: Dermatology Authors: Natalia M Pelet Del Toro Andrew Strunk Jashin J Wu Linda Stein Gold James Q Del Rosso Robert T Brodell George Han Source Type: research

SSRI Behavioral Activation, the Boxed Bolded Warning, and Neurodevelopmental Disorders
J Clin Psychiatry. 2024 Apr 2;85(2):24ac15280. doi: 10.4088/JCP.24ac15280.NO ABSTRACTPMID:38569179 | DOI:10.4088/JCP.24ac15280 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - April 3, 2024 Category: Psychiatry Authors: Mayank Gupta Source Type: research

Development and validation of a comprehensive model to predict complications after hepatectomy
CONCLUSIONS: We developed an accurate and practical scoring system based on preoperative and early postoperative data to predict poor outcomes after hepatectomy. Further external validation on larger series could lead to the integration of such a tool in the routine clinical practice to support patients' management and early warning during ICU stay.GRAPHICAL ABSTRACT: https://www.europeanreview.org/wp/wp-content/uploads/Graphical-Abstract-NEW-2.pdf.PMID:38567611 | DOI:10.26355/eurrev_202403_35758 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: R Gaspari F Ardito P C Pafundi A W Avolio P Aceto E Adducci M Pallocchi E Parente L Sollazzi M Antonelli F Giuliante Source Type: research

Topical clindamycin for acne vulgaris: analysis of gastrointestinal events
Conclusions: According to pharmacovigilance data, the rate of GI adverse drug reactions with topical clindamycin-containing products was 0.000045% (64/141,084,533). Results from two retrospective medical record studies of patients with AV indicated that physicians prescribe topical clindamycin equally to patients with or without inflammatory bowel disease history, and that rates of pseudomembranous colitis in these patients were low. In 8 published pivotal clinical trials of topical clindamycin for AV, GI AEs were reported in 1.4% of participants. Limitations include under/inaccurate reporting of AEs or prescription data a...
Source: Journal of Dermatological Treatment - April 3, 2024 Category: Dermatology Authors: Natalia M Pelet Del Toro Andrew Strunk Jashin J Wu Linda Stein Gold James Q Del Rosso Robert T Brodell George Han Source Type: research

SSRI Behavioral Activation, the Boxed Bolded Warning, and Neurodevelopmental Disorders
J Clin Psychiatry. 2024 Apr 2;85(2):24ac15280. doi: 10.4088/JCP.24ac15280.NO ABSTRACTPMID:38569179 | DOI:10.4088/JCP.24ac15280 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - April 3, 2024 Category: Psychiatry Authors: Mayank Gupta Source Type: research

Development and validation of a comprehensive model to predict complications after hepatectomy
CONCLUSIONS: We developed an accurate and practical scoring system based on preoperative and early postoperative data to predict poor outcomes after hepatectomy. Further external validation on larger series could lead to the integration of such a tool in the routine clinical practice to support patients' management and early warning during ICU stay.GRAPHICAL ABSTRACT: https://www.europeanreview.org/wp/wp-content/uploads/Graphical-Abstract-NEW-2.pdf.PMID:38567611 | DOI:10.26355/eurrev_202403_35758 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: R Gaspari F Ardito P C Pafundi A W Avolio P Aceto E Adducci M Pallocchi E Parente L Sollazzi M Antonelli F Giuliante Source Type: research