The Syntheses of Chromium Aluminum Carbide (Cr < sub > 2 < /sub > AlC) MAX  Phase and Cr < sub > 2 < /sub > CTx MXene and Investigation of Their Antimicrobial Properties
Appl Biochem Biotechnol. 2024 Mar 28. doi: 10.1007/s12010-024-04910-w. Online ahead of print.ABSTRACTChromium aluminum carbide (Cr2AlC) MAX phase and Cr2CTx (MXene-Cr) were synthesized by the pressureless sintering method and hydrothermal method, respectively. In addition to this, the free radical scavenging activities (FRSA) of MAX-Cr phase and MXene-Cr compounds were tested and compared with ascorbic acid and trolox as standard compounds. The obtained FRSA results of MAX-Cr phase and MXene-Cr were 42.82 and 59.64%, respectively, at 100 mg/L concentration. MXene-Cr showed a 66.90% inhibitory effect on α-amylase at 200 mg...
Source: Applied Biochemistry and Biotechnology - March 28, 2024 Category: Biochemistry Authors: Gul Kaya Eda Ondul Koc Sadin Özdemir M Serkan Yal çın Kasim Ocakoglu Nadir Dizge Source Type: research

Molecules, Vol. 29, Pages 1515: Exploring the Chemical Profile, In Vitro Antioxidant and Anti-Inflammatory Activities of Santolina rosmarinifolia Extracts
In this study, the phytochemical composition, in vitro antioxidant, and anti-inflammatory effects of the aqueous and 60% ethanolic (EtOH) extracts of Santolina rosmarinifolia leaf, flower, and root were examined. The antioxidant activity of S. rosmarinifolia extracts was determined by 2,2&amp;rsquo;-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assays. The total phenolic content (TPC) of the extracts was measured by the Folin&amp;ndash;Ciocalteu assay. The anti-inflammatory effect of the extracts was monitored by the Griess assay. The chemical c...
Source: Molecules - March 28, 2024 Category: Chemistry Authors: Schmidt Juhasz Bona Tags: Article Source Type: research

Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research

Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research

Disposable paper electrodes for detection of changes in dopamine concentrations in rat brain homogenates
Talanta. 2024 Mar 26;274:125940. doi: 10.1016/j.talanta.2024.125940. Online ahead of print.ABSTRACTDopamine, the main catecholamine neurotransmitter plays an important role in renal, cardiovascular, central nervous systems, and pathophysiological processes. The abnormal dopamine levels can result in neurological disorders such as Parkinson's, Alzheimer's, schizophrenia, acute anxiety, neuroblastoma and also contribute to cognitive dysfunctions. Given the widespread importance of dopamine concentration levels, it is imperative to develop sensors that are able to monitor dopamine. Herein, we have developed pre-anodized dispo...
Source: Talanta - March 27, 2024 Category: Chemistry Authors: J Sonia B N Kumara Kevin Joakim Pinto A Hashim E S Sindhu Priya B Kalpana Renjtih Thomas K Sudhakara Prasad Source Type: research

Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Mol Biol Cell - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research

Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research

Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research

Disposable paper electrodes for detection of changes in dopamine concentrations in rat brain homogenates
Talanta. 2024 Mar 26;274:125940. doi: 10.1016/j.talanta.2024.125940. Online ahead of print.ABSTRACTDopamine, the main catecholamine neurotransmitter plays an important role in renal, cardiovascular, central nervous systems, and pathophysiological processes. The abnormal dopamine levels can result in neurological disorders such as Parkinson's, Alzheimer's, schizophrenia, acute anxiety, neuroblastoma and also contribute to cognitive dysfunctions. Given the widespread importance of dopamine concentration levels, it is imperative to develop sensors that are able to monitor dopamine. Herein, we have developed pre-anodized dispo...
Source: Talanta - March 27, 2024 Category: Chemistry Authors: J Sonia B N Kumara Kevin Joakim Pinto A Hashim E S Sindhu Priya B Kalpana Renjtih Thomas K Sudhakara Prasad Source Type: research

Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research

Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research

Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research

Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research

Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research

Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research