Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research
Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research
Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research
Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research
Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research
Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research
Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research
Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research
Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research
Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research
Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research
Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research
Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research
Study on Chemical Composition and Biological Activity of < em > Psidium guajava < /em > Leaf Extracts
In this study, the use of concentrated P. guajava leaf extract molecules as a functional natural material was evaluated by confirming the extract's antioxidative, antibacterial, tyrosinase activity inhibition, and collagenase activity inhibition effects and its trans-2-nonenal removal ability. As a result of the analysis of the antioxidant and antibacterial components of concentrated P. guajava leaf extract molecules through GC-MS, a large amount of aromatic hydrocarbon molecules were detected. When different concentrations of ethanol were used for extraction, the leaf extract concentrated with 70% ethanol showed the most ...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Hyonam Park Bohee Kim Yuri Kang Woonjung Kim Source Type: research
Effects of Letrozole Treatment and Vitamin C Supplementation on Morphology, Endoplasmic Reticulum Stress, Programmed Cell Death, and Oxidative Stress in the Small Intestine of Adult Male Rats
Curr Issues Mol Biol. 2024 Mar 1;46(3):1943-1954. doi: 10.3390/cimb46030127.ABSTRACTEstrogens are hormones that play an important role in the digestive tract, including in men. Letrozole is an inhibitor of cytochrome P450 aromatase, an enzyme converting androgens to estrogens. The use of letrozole may cause oxidative stress and endoplasmic reticulum stress in the cells. Factors modulating cellular stress may include vitamin C. The purpose of this study was to examine whether letrozole and/or vitamin C supplementation can affect the morphology of the small intestine, the parameters of endoplasmic reticulum stress, programme...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Anna Pilutin Sylwia Rzeszotek Aleksandra Wilk Klaudia Klimaszewska Julia Łukasiewicz Rufaro Lynnette Mafuta Thanushan Nagendran Rupia Ndambara Barbara Wiszniewska Source Type: research
