Fight Aging! Newsletter, December 4th 2023
This study produced a great deal of data that continues to be mined for insights into human aging and effects of calorie restriction in a long-lived species such as our own, to contrast with the sizable effects on health and longevity in short-lived species such as mice. In particular, and the topic for today, cellular senescence and its role in degenerative aging has garnered far greater interest in the research community in the years since the CALERIE study took place. Thus in today's open access paper, scientists examine CALERIE study data to find evidence for calorie restriction to reduce the burden of cellular ...
Source: Fight Aging! - December 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Mild Mitochondrial Inhibition Slows Aging in Nematode Worms
Researchers here demonstrate that means of mildly inhibiting the production of some of the protein machinery used to generate chemical energy store molecules, adenosine triphosphate, in mitochondria can extend life by 50-70% in nematode worms - a species in which much larger life extension is possible, so this might be viewed as a moderate effect size. Many different approaches to adjusting mitochondrial function can slow aging and extend life in short-lived species. In some cases this works by provoking mitochondria into an alternative pathway for ATP generation that produces a little more oxidative stress than usual, tri...
Source: Fight Aging! - November 30, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Malnutrition Can Impact Wound Healing
Malnutrition can have a significant impact on wound healing. Proper wound healing is a complex process that involves various cellular and biochemical reactions. When the body is malnourished, it lacks the essential nutrients necessary for these processes, which can lead to delayed or impaired wound healing. Here are some key relationships between malnutrition and wound healing: 1. Protein Deficiency: Protein is crucial for tissue repair and the production of collagen, which is essential for wound healing. Malnourishment, especially a lack of adequate protein intake, can lead to a delay in wound closure and reduced tensile ...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - October 2, 2023 Category: Geriatrics Authors: Jeffrey M Levine Tags: An Aging World Featured Medical Articles Geriatric Medicine Long-Term Care Pressure Injuries & Wound Care bedsore bedsores decubiti decubitus ulcer end-of-life care geriatrics gerontology Improving Medical Care Jeff Levine MD J Source Type: blogs

Vitamins and Wound Healing
Wound healing is a complex biological process that involves inflammation, tissue formation, and tissue remodeling. Vitamin supplements can play a role in wound healing by supporting various aspects of the body’s natural healing processes. Here are some key vitamins and minerals that are important for wound healing: Vitamin C: Vitamin C, also known as ascorbic acid, is essential for collagen synthesis, a protein that helps in the formation of skin, blood vessels, and connective tissue. Collagen is a crucial component of wound healing. Adequate vitamin C intake can promote tissue repair and reduce the risk of infectio...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - September 9, 2023 Category: Geriatrics Authors: Jeffrey M Levine Tags: Geriatric Medicine Pressure Injuries & Wound Care aging skin bedsore bedsores decubiti decubitus ulcer geriatrics gerontology Healthcare Quality Improving Medical Care Jeff Levine MD Jeffrey M Levine MD Nursing Homes pressure s Source Type: blogs

A heartbreaking COVID-19 case: the importance of trust in medical care
An excerpt from One Hundred Prayers: God’s answer to prayer in a COVID ICU. (August 30, 2021)  Susan was 44 years old and previously healthy; an ardent anti-masker. When she caught delta COVID, she took ivermectin, zinc and vitamin C. She arrived at our ER about a week later, requiring immediate intubation. Mayfield started her Read more… A heartbreaking COVID-19 case: the importance of trust in medical care originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - August 20, 2023 Category: General Medicine Authors: Tags: Conditions COVID Source Type: blogs

Can You Drink Coconut Water With Hypertension?
Conclusion So, circling back to our initial question: Can you drink coconut water if you have hypertension? The evidence seems to suggest that the answer is yes, provided it’s consumed in moderation, given its potassium and magnesium content. However, one must not overlook potential risks associated with overconsumption. A cornerstone of any dietary change, especially concerning a health condition like hypertension, is professional healthcare advice. Always consult your healthcare provider before making significant changes to your diet. After all, managing hypertension is an individual journey,...
Source: The EMT Spot - June 18, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Fight Aging! Newsletter, June 12th 2023
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 11, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Aptamer to Enhance Vitamin C Antioxidant Function Improves Neurovascular Function in Aged Mice
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 5, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Withings U-Scan: Measuring Waste for Health Benefits at Home
Public health agencies have come to understand the immense value of monitoring waste water, as demonstrated by a recent report calling for its expansion. But Withings allows you to measure your own waste products in the home through a new product called U-Scan. At CES 2023, Julius Dewavrin, Product Manager for U-Scan, explained how U-Scan works and the kinds of health benefits it can provide. More than 3000 components are packed into a disk you can hold in your hand. Just install the device inside the toilet bowl and choose the tests you want it to perform. These include logging your menstrual cycle by detecting hormones i...
Source: EMR and HIPAA - February 1, 2023 Category: Information Technology Authors: Andy Oram Tags: Clinical Health IT Company Healthcare IT Hospital - Health System LTPAC Telemedicine and Remote Monitoring CES CES 2023 CES2023 Healthcare IT Video Interviews Julius Dewavrin Remote Patient Monitoring RPM U-Scan Withings Wome Source Type: blogs

Gene Pathway Analysis In Action – 3 × 4 DNA Test Review
In the past couple of years, I have taken at least 10 genetic tests, including this latest DNA test from 3×4 Genetics. This may seem excessive, but I have my reasons. I graduated from medical school as a genetic specialist and completed my PhD as a clinical genomics researcher, and although I turned to medical futurism, my original field never ceases to fascinate me. I’m very curious about how these tests advance and hope I might be able to provide insights for patients worldwide about what they can expect to learn from such tests and what those tests can really deliver. Thus, I didn’t hesitate for a second to ...
Source: The Medical Futurist - November 24, 2022 Category: Information Technology Authors: Andrea Koncz Tags: Genomics Personalized Medicine dna testing genetic test Genetic testing review dna test review 3x4 Genetics pathway analysis Source Type: blogs

Home Remedies for High Blood Pressure
Lower high blood pressure with these effective home remedies that are easy to apply, whether you’re dealing with mild or more severe cases of the condition. If you’re searching for natural ways to lower your blood pressure, a few home remedies may help. From making some lifestyle changes to eating mindfully, these tips can help you get your numbers down. Talk to your doctor before trying new treatments, and read for more information. Quick Summary Regular exercise can help lower blood pressure by making the heart stronger and more efficient. The DASH diet is a tried-and-tested eating pa...
Source: The EMT Spot - November 1, 2022 Category: Emergency Medicine Authors: bpscore-sibera Tags: Guides Blood Pressure Source Type: blogs

Spanish Sofrito and the Mediterranean Diet
Sofrito topped flatbreads In the largest study of its kind to date, the Mediterranean Diet has trumped a low fat diet in secondary prevention of cardiovascular disease. The study was conducted in Spain, where participants assigned to the Mediterranean diet received free olive oil. They were also instructed to use sofrito – “a homemade sauce with garlic, onion, aromatic herbs, and tomato slow cooked in olive oil” – in their cooking two or more times a week. Free Spanish olive oil and Sofrito as a required food group? I’d have moved to Spain to be in that study! But since that never happen...
Source: The Blog That Ate Manhattan - September 18, 2022 Category: Primary Care Authors: Margaret Polaneczky, MD Tags: Vegetables Vegetarian Mediterranean diet SOfrito Source Type: blogs

The Amount Of Vitamin C That Boosts The Immune System
Experts have estimated how much vitamin C we need relative to our body weight to boost the immune system. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - June 5, 2022 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Nutrition Source Type: blogs

When Do You Think We Can Expect Such Services In OZ?
This appeared last week: April 12, 2022 Walgreens and Wing launch drone delivery in first major U.S. metropolitan area The story behind Walgreens and Wing ’s expansion to Dallas-Fort Worth, a milestone for customers and the drone industry alike. By Sarah Cason, Walgreens Stories It’s a sunny spring morning in Dallas, Texas. Representatives from Walgreens and Alphabet’s Wing are in Simpson Plaza, preparing to launch drone delivery in the Dallas-F ort Worth metroplex. The first two recipients, the mayors of Frisco and Little Elm, have inputted their order into Wing’s app. Minutes later, the drone arrives and safely ...
Source: Australian Health Information Technology - April 28, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs