Fabrication of Long-Range Film of Flower-Like Ag Nanoparticles for Highly Sensitive SERS Substrate
AbstractThe fabrication of sensitive and homogeneous surface-enhanced Raman scattering (SERS) substrates is the key to its practical application. In this paper, flower-like silver nanoparticles (Ag NPs) were successfully synthesized in water/ethanol/n-octanol emulsions by an assistant of citric acid and sodium citrate. The size and surface roughness of flower-like Ag NPs can be adjusted by changing the experimental parameters, such as the ratio of citric acid to sodium citrate, and the concentration of ascorbic acid. The resulting flower-like Ag NPs were constructed to form a homogeneous single-layer film by a three-phase ...
Source: Plasmonics - April 20, 2024 Category: Biomedical Science Source Type: research

Poly (aniline-co-aniline-2,5-disulfonic acid) / L-ascorbic acid / Ag@SiO2 / polysafranin nanocomposite: synthesis, characterization and anomalous electrical behaviour
We report the synthesis of sulfonated copolyaniline/polysafranin/L-ascorbic acid/Ag@SiO2 fine powdered nanocomposites and investigate the influence of incorporating the dye on their conductivity. The composite wa... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 20, 2024 Category: Chemistry Authors: Hammed H. A. M. Hassan, Marwa Abdel Fattah and Fatma Abdel Maged Tags: Research Source Type: research

Neutrophil Extracellular Traps Regulate Surgical Brain Injury by Activating the cGAS-STING Pathway
In this study, we found that neutrophil extracellular traps (NETs) were present in the circulation and brain tissues of rats after SBI, which promoted neuroinflammation, cerebral edema, neuronal cell death, and aggravated neurological dysfunction. Inhibition of NETs formation by peptidylarginine deiminase (PAD) inhibitor or disruption of NETs with deoxyribonuclease I (DNase I) attenuated SBI-induced damages and improved the recovery of neurological function. We show that SBI triggered the activation of cyclic guanosine monophosphate-adenosine monophosphate synthase stimulator of interferon genes (cGAS-STING), and that inhi...
Source: Cellular and Molecular Neurobiology - April 18, 2024 Category: Cytology Authors: Bingbing Li Lixia Xu Zhengang Wang Qi Shi Yang Cui Weijia Fan Qiaoli Wu Xiaoguang Tong Hua Yan Source Type: research

Uremia Impedes Skeletal Myocyte Myomixer Expression and Fusogenic Activity
In patients with chronic kidney disease (CKD), skeletal muscle mass and function are known to occasionally decline. However, the muscle regeneration and differentiation process in uremia has not been extensively studied. In mice with CKD induced by adenine-containing diet, the tibialis anterior muscle injured using a barium chloride injection method recovered poorly as compared to control mice. In the cultured murine skeletal myocytes, stimulation with indoxyl sulfate (IS), a representative uremic toxin, morphologically jeopardized the differentiation, which was counteracted by L-ascorbic acid (L-AsA) treatment. (Source: A...
Source: American Journal of Pathology - April 17, 2024 Category: Pathology Authors: Takaaki Higashihara, Motoki Odawara, Hiroshi Nishi, Takehito Sugasawa, Yumika Suzuki, Satoshi Kametaka, Reiko Inagi, Masaomi Nangaku Tags: Regular Article Source Type: research

Ascorbic acid as a modulator of inflammatory response against Candida albicans
Future Microbiology, Ahead of Print. (Source: Future Microbiology)
Source: Future Microbiology - April 17, 2024 Category: Microbiology Authors: Noala Vicensoto Moreira Milhan Aline da Gra ça Sampaio Cristiane Yumi Koga-Ito Angela Bruzzaniti Source Type: research

Characteristics of Nutrition and Metabolism in Dogs and Cats
Adv Exp Med Biol. 2024;1446:55-98. doi: 10.1007/978-3-031-54192-6_4.ABSTRACTDomestic dogs and cats have evolved differentially in some aspects of nutrition, metabolism, chemical sensing, and feeding behavior. The dogs have adapted to omnivorous diets containing taurine-abundant meat and starch-rich plant ingredients. By contrast, domestic cats must consume animal-sourced foods for survival, growth, and development. Both dogs and cats synthesize vitamin C and many amino acids (AAs, such as alanine, asparagine, aspartate, glutamate, glutamine, glycine, proline, and serine), but have a limited ability to form de novo arginine...
Source: Advances in Experimental Medicine and Biology - April 16, 2024 Category: Research Authors: Peng Li Guoyao Wu Source Type: research

Recent Advances in the Nutrition and Metabolism of Dogs and Cats
Adv Exp Med Biol. 2024;1446:1-14. doi: 10.1007/978-3-031-54192-6_1.ABSTRACTDomestic dogs (facultative carnivores) and cats (obligate carnivores) have been human companions for at least 12,000 and 9000 years, respectively. These animal species have a relatively short digestive tract but a large stomach volume and share many common features of physiological processes, intestinal microbes, and nutrient metabolism. The taste buds of the canine and feline tongues can distinguish sour, umami, bitter, and salty substances. Dogs, but not cats, possess sweet receptors. α-Amylase activity is either absent or very low in canine and ...
Source: Advances in Experimental Medicine and Biology - April 16, 2024 Category: Research Authors: Guoyao Wu Source Type: research

Characteristics of Nutrition and Metabolism in Dogs and Cats
Adv Exp Med Biol. 2024;1446:55-98. doi: 10.1007/978-3-031-54192-6_4.ABSTRACTDomestic dogs and cats have evolved differentially in some aspects of nutrition, metabolism, chemical sensing, and feeding behavior. The dogs have adapted to omnivorous diets containing taurine-abundant meat and starch-rich plant ingredients. By contrast, domestic cats must consume animal-sourced foods for survival, growth, and development. Both dogs and cats synthesize vitamin C and many amino acids (AAs, such as alanine, asparagine, aspartate, glutamate, glutamine, glycine, proline, and serine), but have a limited ability to form de novo arginine...
Source: Advances in Experimental Medicine and Biology - April 16, 2024 Category: Research Authors: Peng Li Guoyao Wu Source Type: research

Recent Advances in the Nutrition and Metabolism of Dogs and Cats
Adv Exp Med Biol. 2024;1446:1-14. doi: 10.1007/978-3-031-54192-6_1.ABSTRACTDomestic dogs (facultative carnivores) and cats (obligate carnivores) have been human companions for at least 12,000 and 9000 years, respectively. These animal species have a relatively short digestive tract but a large stomach volume and share many common features of physiological processes, intestinal microbes, and nutrient metabolism. The taste buds of the canine and feline tongues can distinguish sour, umami, bitter, and salty substances. Dogs, but not cats, possess sweet receptors. α-Amylase activity is either absent or very low in canine and ...
Source: Advances in Experimental Medicine and Biology - April 16, 2024 Category: Research Authors: Guoyao Wu Source Type: research

Empowering γδ T-cell functionality with vitamin C
Eur J Immunol. 2024 Apr 15:e2451028. doi: 10.1002/eji.202451028. Online ahead of print.ABSTRACTVitamin C (ascorbic acid) is a potent antioxidant and a cofactor for various enzymes including histone demethylases and methylcytosine dioxygenases. Vitamin C also exerts direct cytotoxicity toward selected tumor cells including colorectal carcinoma. Moreover, vitamin C has been shown to impact immune cell differentiation at various levels including maturation and/or functionality of T cells and their progenitors, dendritic cells, B cells, and NK cells. γδ T cells have recently attracted great interest as effector cells for cel...
Source: European Journal of Immunology - April 15, 2024 Category: Allergy & Immunology Authors: Dieter Kabelitz Lea Cierna Claudia Juraske Michal Zarobkiewicz Wolfgang W Schamel Christian Peters Source Type: research

Near-infrared light-induced homogeneous photoelectrochemical biosensor based on 3D walking nanomotor-assisted CRISPR/Cas12a for ultrasensitive microRNA-155 detection
J Colloid Interface Sci. 2024 Apr 3;667:82-90. doi: 10.1016/j.jcis.2024.04.012. Online ahead of print.ABSTRACTThe dysregulation of microRNA (miRNA) expression levels is intricately linked to a myriad of human diseases, and the precise and delicate detection thereof holds paramount significance in the realm of clinical diagnosis and therapy. Herein, a near-infrared (NIR) light-mediated homogeneous photoelectrochemical (PEC) biosensor was constructed for miRNA-155 detection based on NaYF4: Yb, Tm@ZnIn2S4 (NYF@ ZIS) coupled with a three-dimensional (3D) walking nanomotor-assisted CRISPR/Cas12a strategy. The upconverted light ...
Source: Anal Sci - April 15, 2024 Category: Chemistry Authors: Pei Miao Yan Sun Gengxiu Zheng Bin Wang Wenshou Wang Jing Zhang Mei Yan Yanfeng Lv Source Type: research

Empowering γδ T-cell functionality with vitamin C
Eur J Immunol. 2024 Apr 15:e2451028. doi: 10.1002/eji.202451028. Online ahead of print.ABSTRACTVitamin C (ascorbic acid) is a potent antioxidant and a cofactor for various enzymes including histone demethylases and methylcytosine dioxygenases. Vitamin C also exerts direct cytotoxicity toward selected tumor cells including colorectal carcinoma. Moreover, vitamin C has been shown to impact immune cell differentiation at various levels including maturation and/or functionality of T cells and their progenitors, dendritic cells, B cells, and NK cells. γδ T cells have recently attracted great interest as effector cells for cel...
Source: European Journal of Immunology - April 15, 2024 Category: Allergy & Immunology Authors: Dieter Kabelitz Lea Cierna Claudia Juraske Michal Zarobkiewicz Wolfgang W Schamel Christian Peters Source Type: research

Near-infrared light-induced homogeneous photoelectrochemical biosensor based on 3D walking nanomotor-assisted CRISPR/Cas12a for ultrasensitive microRNA-155 detection
J Colloid Interface Sci. 2024 Apr 3;667:82-90. doi: 10.1016/j.jcis.2024.04.012. Online ahead of print.ABSTRACTThe dysregulation of microRNA (miRNA) expression levels is intricately linked to a myriad of human diseases, and the precise and delicate detection thereof holds paramount significance in the realm of clinical diagnosis and therapy. Herein, a near-infrared (NIR) light-mediated homogeneous photoelectrochemical (PEC) biosensor was constructed for miRNA-155 detection based on NaYF4: Yb, Tm@ZnIn2S4 (NYF@ ZIS) coupled with a three-dimensional (3D) walking nanomotor-assisted CRISPR/Cas12a strategy. The upconverted light ...
Source: Anal Sci - April 15, 2024 Category: Chemistry Authors: Pei Miao Yan Sun Gengxiu Zheng Bin Wang Wenshou Wang Jing Zhang Mei Yan Yanfeng Lv Source Type: research

Monitoring the utilization and effectiveness of Iron and Vitamin D supplementations program and its predictive factors in high schools ’ girls in Qom, Iran
Conclusion:The inadequate and incomplete rate of IVDSP in Qom was high and more than 60% of distributed supplementations have been wasted. Our results showed that students who were participated in educational orientation classes were more successful and eager in iron and vitamin D3 consumption.  Therefore, it is recommended to increase interventions at individual, interpersonal, intra-organizational and inter-organizational levels in order to fully support the program and ultimately increase the efficiency of the program.  (Source: Journal of Preventive Medicine and Hygiene)
Source: Journal of Preventive Medicine and Hygiene - April 15, 2024 Category: International Medicine & Public Health Authors: Abolfazl Mohammadbeigi, Dr Source Type: research

Essential oil of the leaves of < em > psychotria asiatica < /em > L.: chemical composition, antioxidant, anti-inflammatory, and cytotoxic properties
This study is focused on investigating the chemical composition and bioactive properties of the essential oil extracted from Psychotria asiatica L., a plant species known for its medicinal properties. Utilising gas chromatography-mass spectrometry (GC-MS) analysis, the essential oil from P. asiatica was found to contain 53 distinct constituents. Major compounds identified include (E)-citral (20.6%), 10-epi-γ-eudesmol (15.9%), (Z)-citral (10.5%), geraniol (7.4%), α-cadinol (6.7%), 7-epi-α-eudesmol (4.4%), linalool (3.7%), and α-muurolol (3.4%). The essential oil did not exhibit antioxidant activity, as indicated by an I...
Source: Cancer Control - April 13, 2024 Category: Cancer & Oncology Authors: Tien Dong Tran Anh Tuan Le Dat Van Tran Thang Quoc Le Ty Viet Pham Source Type: research