A Predictive Model for Thiamine Responsive Disorders among Infants and Young Children: Results from a Prospective Cohort Study in Lao People ’s Democratic Republic
To develop a predictive model for thiamine responsive disorders (TRD) among infants and young children hospitalized with signs or symptoms suggestive of thiamine deficiency disorders (TDD) based on response to therapeutic thiamine in a high-risk setting. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - February 16, 2024 Category: Pediatrics Authors: Taryn J. Smith, Charles D. Arnold, Philip R. Fischer, Indi Trehan, Laurent Hiffler, Dalaphone Sitthideth, Rebecca Stein-Wexler, Jay Yeh, Kerry S. Jones, Daniela Hampel, Daniel J. Tancredi, Michael A. Schick, Christine N. McBeth, Xiuping Tan, Lindsay H. Al Tags: Original Articles Source Type: research
Association between dietary vitamin B1 intake and cognitive function among older adults: a cross-sectional study
This study aims to investigate the relationship between vitamin B1 intake and cognitive function in older adults. (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - February 16, 2024 Category: Research Authors: Weiai Jia, Hemei Wang, Chao Li, Jingpu Shi, Fangfang Yong and Huiqun Jia Tags: Research Source Type: research
Long-term follow-up of an attenuated presentation of NAXE-related disease, a potentially actionable neurometabolic disease: a case report
ConclusionA missense homozygous variant in the NAXE gene is described in this patient with a milder clinical phenotype of the disease. Supplementation with niacin in addition to a mitochondrial cocktail presents a potential supportive therapeutic option to reduce disease progression. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 14, 2024 Category: Neurology Source Type: research
Whole blood thiamine, intravenous thiamine supplementation and delirium occurrence in the intensive care unit: retrospective cohort analyses
ConclusionNo relationship was detected between whole blood thiamine and delirium occurrence on admission, at 24 and 48 h. It remains unclear whether routine intravenous thiamine supplementation during intensive care admission impacts delirium occurrence. Further prospective randomised clinical trials are needed. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - February 8, 2024 Category: Drugs & Pharmacology Source Type: research
Thiamine administration in septic shock: a post hoc analysis of two randomized trials
This is a post hoc analysis of combined cohorts from two previous Phase II clinical trials to assess the effect of thiamine administration on kidney protection and mortality in patients with septic shock. (Source: Critical Care)
Source: Critical Care - February 6, 2024 Category: Intensive Care Authors: Jacob Vine, John H. Lee, Max S. Kravitz, Anne V. Grossestreuer, Lakshman Balaji, Shannon B. Leland, Noa Berlin, Ari Moskowitz and Michael W. Donnino Tags: Brief Report Source Type: research
Women in Canada are consuming above the upper intake level of folic acid but few are meeting dietary choline recommendations in the second trimester of pregnancy: data from the CHILD cohort study
The objective of this study was to determine folic acid supplement use and dietary folate intakes in the second trimester (week 18) of pregnancy in women (n = 2996) in the Canadian CHILD cohort study. Vitamin B1 2 and choline intakes were also assessed because they are metabolically related to folate. The majority of participants (71.6%) were consuming a daily prenatal supplement. Twenty-eight percent of women (n = 847) reported consuming a folic acid supplement and of these women, 45.3% had daily supplem ental folic acid intakes above the upper intake level (UL; 1000 µg/day). Daily dietary folate intakes were (mean (...
Source: Applied Physiology, Nutrition, and Metabolism - February 6, 2024 Category: Physiology Authors: Alejandra M. Wiedeman Kozeta Miliku Theo J. Moraes Piushkumar J. Mandhane Elinor Simons Padmaja Subbarao Stuart E. Turvey Jill G. Zwicker Angela M. Devlin Source Type: research
The Management of Nausea and Vomiting in Pregnancy and Hyperemesis Gravidarum (Green-top Guideline No. 69)
BJOG. 2024 Feb 4. doi: 10.1111/1471-0528.17739. Online ahead of print.ABSTRACTAn objective and validated index of nausea and vomiting such as the Pregnancy-Unique Quantification of Emesis (PUQE) and HyperEmesis Level Prediction (HELP) tools can be used to classify the severity of NVP and HG. [Grade C] Ketonuria is not an indicator of dehydration and should not be used to assess severity. [Grade A] There are safety and efficacy data for first line antiemetics such as anti (H1) histamines, phenothiazines and doxylamine/pyridoxine (Xonvea®) and they should be prescribed initially when required for NVP and HG (Appendix III). ...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - February 4, 2024 Category: OBGYN Authors: Catherine Nelson-Piercy Caitlin Dean Manjeet Shehmar Roger Gadsby Margaret O'Hara Kenneth Hodson Melanie Nana Royal College of Obstetricians and Gynaecologists Source Type: research
Evaluation of the amelioration effect of Ganoderma formosanum extract on delaying PM2.5 damage to lung macrophages
ConclusionsThe study suggests that the WA has the potential to alleviate the PM -induced damage in alveolar macrophages, demonstrating its anti-inflammatory properties. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 29, 2024 Category: Food Science Authors: Chih ‐Yao Hou,
Chen‐Che Hsieh,
Yin‐Ci Hung,
Cheng‐Chih Hsu,
Chang‐Wei Hsieh,
Shu‐Han Yu,
Kuan‐Chen Cheng Tags: Research Article Source Type: research
