Metabolomics analyses of cancer tissue from patients with colorectal cancer
In conclusion, the present study demonstrated that CRC tumors had altered metabolites compared with normal tissue. The data from the metabolic profile of CRC tissues in the present study provided supportive evidence to understand tumorigenesis.PMID:37772396 | DOI:10.3892/mmr.2023.13106 (Source: Molecular Medicine)
Source: Molecular Medicine - September 29, 2023 Category: Molecular Biology Authors: Chunbo Kang Jie Zhang Mei Xue Xiaowei Li Danyang Ding Ye Wang Shujing Jiang Fong-Fong Chu Qiang Gao Mengqiao Zhang Source Type: research
Metabolomics analyses of cancer tissue from patients with colorectal cancer
In conclusion, the present study demonstrated that CRC tumors had altered metabolites compared with normal tissue. The data from the metabolic profile of CRC tissues in the present study provided supportive evidence to understand tumorigenesis.PMID:37772396 | DOI:10.3892/mmr.2023.13106 (Source: Molecular Medicine Reports)
Source: Molecular Medicine Reports - September 29, 2023 Category: Molecular Biology Authors: Chunbo Kang Jie Zhang Mei Xue Xiaowei Li Danyang Ding Ye Wang Shujing Jiang Fong-Fong Chu Qiang Gao Mengqiao Zhang Source Type: research
Analysis on the in-silico ensemble methods for 3D modelling of ssDNA aptamers
This study identified that the Guanine residues are crucial in the aptamer 3D structure prediction and in algorithms that generate secondary structures. Further, the GC content (<50%), GC bond percentage (<60%), and G:C ratio (<1.12) act as limiting factors in predicting the 2D structures of aptamers. There were variations in the 2D structure predictions by the web applications, even though all these applications were a combination of the MFE, MEA, and McCaskill functions. Processing these structures through the web applications described above produced best-fit 3D structures with the experimental one, thus offeri...
Source: Biophysical Chemistry - September 29, 2023 Category: Chemistry Authors: Vinay Bachu Kangkana Barman Pranab Goswami Source Type: research
Metabolomics analyses of cancer tissue from patients with colorectal cancer
In conclusion, the present study demonstrated that CRC tumors had altered metabolites compared with normal tissue. The data from the metabolic profile of CRC tissues in the present study provided supportive evidence to understand tumorigenesis.PMID:37772396 | DOI:10.3892/mmr.2023.13106 (Source: Molecular Medicine)
Source: Molecular Medicine - September 29, 2023 Category: Molecular Biology Authors: Chunbo Kang Jie Zhang Mei Xue Xiaowei Li Danyang Ding Ye Wang Shujing Jiang Fong-Fong Chu Qiang Gao Mengqiao Zhang Source Type: research
Metabolomics analyses of cancer tissue from patients with colorectal cancer
In conclusion, the present study demonstrated that CRC tumors had altered metabolites compared with normal tissue. The data from the metabolic profile of CRC tissues in the present study provided supportive evidence to understand tumorigenesis.PMID:37772396 | DOI:10.3892/mmr.2023.13106 (Source: Molecular Medicine Reports)
Source: Molecular Medicine Reports - September 29, 2023 Category: Molecular Biology Authors: Chunbo Kang Jie Zhang Mei Xue Xiaowei Li Danyang Ding Ye Wang Shujing Jiang Fong-Fong Chu Qiang Gao Mengqiao Zhang Source Type: research
Analysis on the in-silico ensemble methods for 3D modelling of ssDNA aptamers
This study identified that the Guanine residues are crucial in the aptamer 3D structure prediction and in algorithms that generate secondary structures. Further, the GC content (<50%), GC bond percentage (<60%), and G:C ratio (<1.12) act as limiting factors in predicting the 2D structures of aptamers. There were variations in the 2D structure predictions by the web applications, even though all these applications were a combination of the MFE, MEA, and McCaskill functions. Processing these structures through the web applications described above produced best-fit 3D structures with the experimental one, thus offeri...
Source: Biophysical Chemistry - September 29, 2023 Category: Chemistry Authors: Vinay Bachu Kangkana Barman Pranab Goswami Source Type: research
Metabolomics analyses of cancer tissue from patients with colorectal cancer
In conclusion, the present study demonstrated that CRC tumors had altered metabolites compared with normal tissue. The data from the metabolic profile of CRC tissues in the present study provided supportive evidence to understand tumorigenesis.PMID:37772396 | DOI:10.3892/mmr.2023.13106 (Source: Molecular Medicine Reports)
Source: Molecular Medicine Reports - September 29, 2023 Category: Molecular Biology Authors: Chunbo Kang Jie Zhang Mei Xue Xiaowei Li Danyang Ding Ye Wang Shujing Jiang Fong-Fong Chu Qiang Gao Mengqiao Zhang Source Type: research
Genomic insight and physiological characterization of thermoacidophilic Alicyclobacillus isolated from Yellowstone National Park
IntroductionAlicyclobacillus has been isolated from extreme environments such as hot springs, volcanoes, as well as pasteurized acidic beverages, because it can tolerate extreme temperatures and acidity. In our previous study, Alicyclobacillus was isolated during the enrichment of methane oxidizing bacteria from Yellowstone Hot Spring samples.MethodsPhysiological characterization and genomic exploration of two new Alicyclobacillus isolates, AL01A and AL05G, are the main focus of this study to identify their potential relationships with a thermoacidophilic methanotroph (Methylacidiphilum) isolated from the same hot spring s...
Source: Frontiers in Microbiology - September 26, 2023 Category: Microbiology Source Type: research
Comparative effect of a nutraceutical compound based on a flavonoid complex from bergamot on plasma lipids, glucose metabolism, and liver enzymes: a 3-arm, double-blind, placebo-controlled, randomized clinical trial
CONCLUSIONS: the tested nutraceutical compound based on a flavonoid complex from bergamot and opuntia showed a short-term positive impact on plasma lipids, fasting plasma glucose, and liver enzyme in overall healthy subjects affected by hypercholesterolaemia with low cardiovascular risk.PMID:37732027 | PMC:PMC10507781 | DOI:10.5114/aoms/152791 (Source: Archives of Medical Science)
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Federica Fogacci Valentina Di Micoli Maddalena Veronesi Arrigo F G Cicero Source Type: research
