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Your NEJM Group Today: Salt-and-Pepper Skin Changes / Vitamin C, Thiamine, & Hydrocortisone for Sepsis / Ohio IM Opportunities (FREE)
By the Editors Have a look at some of the latest clinical content from NEJM Group:NEJM Clinical Practice Center: Images in clinical medicine: A … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 19, 2017 Category: Primary Care Source Type: news

Study finds infant vitamin B1 deficiency leads to poor motor function
Researchers at Tel Aviv University have found that infantile vitamin B1 deficiency severely affected motor function in preschoolers. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 29, 2017 Category: Consumer Health News Source Type: news

Infant vitamin B1 deficiency leads to poor motor function and balance
A new study found that infantile vitamin B1 (thiamine) deficiency severely affected the motor function of preschoolers who were fed faulty formula in the first year of their lives. The conclusions were based on a retrospective study of children who received Remedia, an Israeli formula brand completely lacking in vitamin B1, in 2004. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 29, 2017 Category: Science Source Type: news

Infant vitamin B1 deficiency leads to poor motor function and balance
(American Friends of Tel Aviv University) A new Tel Aviv University study found that infantile vitamin B1 (thiamine) deficiency severely affected the motor function of preschoolers who were fed faulty formula in the first year of their lives. The conclusions were based on a retrospective study of children who received Remedia, an Israeli formula brand completely lacking in vitamin B1, in 2004. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 29, 2017 Category: Global & Universal Source Type: news

The J.M. Smucker Company Expands Limited Voluntary Recall on Certain Lots of Canned Cat Food Due to Low Levels of Thiamine (Vitamin B1)
Orrville, OH - The J.M. Smucker Company is expanding the limited voluntary recall on certain lots of 9LivesTM, EverPetTM, and Special KittyTM canned cat food due to possible low levels of thiamine (Vitamin B1). (Source: Food and Drug Administration)
Source: Food and Drug Administration - January 11, 2017 Category: Food Science Source Type: news

The J.M. Smucker Company Announces a Limited Voluntary Recall on Certain Lots of Canned Cat Food Due to Low Levels of Thiamine (Vitamin B1)
Orrville, OH - The J.M. Smucker Company today announced a limited voluntary recall on certain lots of 9LivesTM, EverPetTM, and Special KittyTM canned cat food due to possible low levels of thiamine (Vitamin B1). (Source: Food and Drug Administration)
Source: Food and Drug Administration - January 3, 2017 Category: Food Science Source Type: news

Salmon, blue mussel, eider, and eel die from the same vitamin deficiency
Deficiency of vitamin B1 (thiamine) in wildlife is previously known as a problem among certain species within relatively limited geographical areas. Now, researchers show that the thiamine deficiency is far more widespread than previously realized. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 13, 2016 Category: Science Source Type: news

Salmon, blue mussel, eider, and eel die from the same vitamin deficiency
(Stockholm University) Deficiency of vitamin B1 (thiamine) in wildlife is previously known as a problem among certain species within relatively limited geographical areas. Now, researchers at Stockholm University, together with several other research institutions in Europe and North America, show that the thiamine deficiency is far more widespread than previously realized. The results are published today in the highly ranked journal Scientific Reports. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 13, 2016 Category: Global & Universal Source Type: news

Alcoholic ketoacidosis: case report and review
3.5 out of 5 stars A Patient with Alcoholic Ketoacidosis and Profound Lactemia. Gerrity RS et al. J Emerg Med 2016 Oct;51:447-449. Abstract This is a very good short case-based review of alcoholic ketoacidosis (AKA), and well-worth the 5 – 10 minutes reading time. Some key points: Development of AKA requires increased (binge) alcohol intake along with starvation (decreased food and water intake.) The characteristic high anion gap metabolic acidosis with elevated lactate and β-hydroxybutyrate levels are the result of dehydration, decreased glycogen stores, increased reducing potential (increased NADH) ...
Source: The Poison Review - October 12, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical alcoholic ketoacidosis fluid repletion Review thiamine TUSH ultrasound Source Type: news

Thiamine as a Metabolic Resuscitator in Septic ShockThiamine as a Metabolic Resuscitator in Septic Shock
A new study looks at the potential therapeutic role of IV thiamine administration in septic shock patients with elevated lactate levels. Critical Care Medicine (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - March 4, 2016 Category: Intensive Care Tags: Critical Care Journal Article Source Type: news

Got PMS? You Might Have High Blood Pressure In The Future, Says Study
By: Agata Blaszczak Boxe Published: 11/25/2015 10:14 AM EST on LiveScience The headaches, fatigue and other symptoms of premenstrual syndrome may be more than just a monthly aggravation — they may also signal greater future health problems for those women suffering from the syndrome: Women who have PMS may have an increased risk of developing high blood pressure in the future, according to a new study. Researchers found that the women who had PMS at the beginning of the study were 40 percent more likely to develop high blood pressure over the next 20 years, compared to women who experienced few menstrual symptom...
Source: Science - The Huffington Post - November 26, 2015 Category: Science Source Type: news

6 Human Foods You Should Never Feed Your Cat
His tiny whiskers and swishy tail are so sweet it can be hard to resist giving him whatever he wants, but there are certain foods you should never feed your cat. Many human foods can put your little guy at risk for gastrointestinal problems, restlessness and worse. As the devoted pet owner that you are, the safest bet is to teach your cat that the food on the dinner table is for people only, and the food in his bowl can be enjoyed to the fullest. There are certain human treats you and your cat can share -- really small servings of cooked vegetables and fish are OK for kitties, for example. But when in doubt, it's best to s...
Source: Science - The Huffington Post - June 24, 2015 Category: Science Source Type: news

ACEP Toxicology Section Antidote App (free)
This simple but very useful app, from the Toxicology Section of the American College of Emergency Physicians, provides basic information about uses and dosing of basic antidotes used in toxicology. Version 1.1 covers approximately 50 different antidotes from A (acetylcysteine) to T (thiamine). Of course, clinical judgment is still required when considering these treatments, and most situations requiring use of the antidotes listed would justify consultation with a poison center. For example, one of the potential indications listed for hyperbaric oxygen (HBO) therapy in carbon monoxide (CO) poisoning is myocardial ischemia....
Source: The Poison Review - March 27, 2015 Category: Toxicology Authors: Leon Tags: Medical ACEP american college of emergency physicians android antidotes app iOS Source Type: news

Surely the NEJM could do a better review of delirium tremens
2.5 out of 5 stars Recognition and Management of Withdrawal Delirium (Delirium Tremens). Schuckit MA. N Engl J Med 2014 Nov 27;371:2109-2113. No abstract available This is an amazingly inept paper, even by the traditionally low standards of the New England Journal‘s  “Review Article” section. It was written by a psychiatrist who — on the basis of this piece — seems not to deal with severe alcohol withdrawal or delirium tremens at all. At times, the author does not appear to appreciate the serious nature of DTs and the difficulty of treating the condition adequately. For instance...
Source: The Poison Review - December 18, 2014 Category: Toxicology Authors: Leon Tags: Medical alcohol withdrawal delirium tremens DTs review article Source Type: news

Tox on the Web: deadly cocaine/fentanyl combination, the rising price of naloxone, and more
  Cocaine/Fentanyl Kills 3 in North Carolina: WTVD-ABC Eyewitness News in Raleigh, North Carolina reports that 3 people local Chatham County died over the weekend — and another 6 were taken to hospital — after using cocaine that had been surreptitiously adulterated with fentanyl. This is somewhat unusual, although many deaths in the past have been caused by fentanyl-laced heroin. A similar death occurred recently in Upstate New York. Naloxone Sticker Shock: The New York Times reported that with demand for intranasal naloxone increasing exponentially as take-home programs and use b...
Source: The Poison Review - December 8, 2014 Category: Toxicology Authors: Leon Tags: Medical cocaine fentanyl death. gastric lavage fatality robert hoffman tox on the web Source Type: news

Vitamin B1 deficiency can cause permanent brain damage and coma, but is rarely diagnosed
(NaturalNews) Thiamine, or vitamin B1, is one of eight distinct members of the B complex, which helps maintain or improve brain and nervous system functioning and liver health, and resist the effects of stress on the immune system. Thiamine was named B1 simply because it was the first... (Source: NaturalNews.com)
Source: NaturalNews.com - September 20, 2014 Category: Consumer Health News Source Type: news

Not enough vitamin B1 can cause brain damage
A deficiency of a single vitamin, B1 (thiamine), can cause a potentially fatal brain disorder called Wernicke encephalopathy. Symptoms can include confusion, hallucinations, loss of muscle coordination and vision problems. Untreated, the condition can lead to irreversible brain damage and death. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 11, 2014 Category: Science Source Type: news

Not enough vitamin B1 can cause brain damage
(Loyola University Health System) A deficiency of a single vitamin, B1 (thiamine), can cause a potentially fatal brain disorder called Wernicke encephalopathy. Symptoms can include confusion, hallucinations, coma, loss of muscle coordination and vision problems such as double vision and involuntary eye movements. Untreated, the condition can lead to irreversible brain damage and death. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 11, 2014 Category: Global & Universal Source Type: news

Not all phytoplankton in the ocean need to take their vitamins
Some species of marine phytoplankton, such as the prolific bloomer Emiliania huxleyi, which can grow so big it can be seen from space, can grow without consuming vitamin B1 (thiamine), researchers have discovered. Until now, many marine microbes with cells that have a nucleus -- eukaryotes -- were thought to depend on other organisms to produce thiamine. If this were the case, B1 would be a major factor in controlling the growth of algae such as E. huxleyi. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 29, 2014 Category: Science Source Type: news

Not all phytoplankton in the ocean need to take their vitamins
(Canadian Institute for Advanced Research) Some species of marine phytoplankton, such as the prolific bloomer Emiliania huxleyi, can grow without consuming vitamin B1 (thiamine), researchers have discovered. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 29, 2014 Category: Biology Source Type: news

Recipe : Crunchy Flax Crusted Salmon
(Healthcastle.com) Looking for a quick and easy, family friendly fish recipe with some crunch and kick? Well you’re in luck! Try out a new salmon recipe that can be pulled together and in the oven in under 10 minutes for a weeknight meal that’s sure to please. Healthy Perks Salmon is rich in anti-inflammatory and heart healthy omega  3’s Flax provides heart and gut friendly soluble fibre, extra omega 3’s and is a good source of magnesium and thiamine. read more (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians - February 24, 2014 Category: Nutrition Source Type: news

Genetics Home Reference: biotin-thiamine-responsive basal ganglia disease
http://ghr.nlm.nih.gov/condition/biotin-thiamine-responsive-basal-ganglia-disease (Source: NLM General Announcements)
Source: NLM General Announcements - January 23, 2014 Category: Databases & Libraries Source Type: news

Nutrition 101: Thiamin
(HealthCastle.com) Thiamin, also spelled thiamine and known as Vitamin B1, is one of eight B vitamins. All of the B vitamins are water soluble, meaning that the body does not store them but excretes them in the urine.   Recommended Intakes The Dietary Reference Intakes (DRI) for thiamin are shown below: read more (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians - August 26, 2013 Category: Nutrition Source Type: news

Australian researchers find new drug to tackle malaria
Australian researchers said that a new drug that stops the malaria parasite from using vitamin B1 to multiply is now plausible. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 22, 2013 Category: Pharmaceuticals Source Type: news

Keeping Bugs Away: 5 Things You Need To Know
The other day, as dusk fell on an afternoon outdoor party, my kids started swatting and itching. Oh, that’s right, I thought: it’s mosquito season. I remembered hearing about West Nile virus being found in some mosquitoes and kicked myself for not bringing bug spray. At the same party, a friend showed me a rash on her son’s leg. By the next day, it had turned into a classic Lyme disease rash. Definitely bug season. If you haven’t done so already, it’s time to get smart about preventing mosquito and tick bites. Here’s what you need to know: 1. The best protection against both mosquitoes a...
Source: Thrive, Children's Hospital Boston - July 5, 2013 Category: Pediatrics Authors: Claire McCarthy Tags: All posts Claire McCarthy, MD Health & wellness Seasonal health bug spray insect repellent is it safe to use bug spray on my kids? protecting against insects Source Type: news

Supplementary Thiamine: Still Important in Alcohol DependenceSupplementary Thiamine: Still Important in Alcohol Dependence
Even with the addition of thiamine to many food products, inadequate intake of thiamine may still put alcoholics at risk of deficiency. Alcohol and Alcoholism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 21, 2013 Category: Consumer Health News Tags: Psychiatry Journal Article Source Type: news