Vitamin deficiencies in children: Lessons from clinical and neuroimaging findings
CONCLUSIONS: Acquired vitamin deficiencies may display reversible clinical symptoms mimicking inherited metabolic disorders. Some situations raise suspicion for diagnosis: concordant clinical presentation, suggestive neuroimaging findings, and/or biochemical evidence. Any acute neurological condition should be treated without waiting for definitive biochemical confirmation.PMID:38520815 | DOI:10.1016/j.ejpn.2024.02.013 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - March 23, 2024 Category: Neurology Authors: Gabrielle Dupuy Charles-Joris Roux R émi Barrois Apolline Imbard Cl ément Pontoizeau Marie Th érèse Dangles M élodie Aubart Jean-Baptiste Arnoux Diane Margoses Ana ïs Brassier Clothilde Marbach Claire-Marine B érat Eug énie Sarda Cyril Gitiaux Pas Source Type: research

Vitamin deficiencies in children: Lessons from clinical and neuroimaging findings
CONCLUSIONS: Acquired vitamin deficiencies may display reversible clinical symptoms mimicking inherited metabolic disorders. Some situations raise suspicion for diagnosis: concordant clinical presentation, suggestive neuroimaging findings, and/or biochemical evidence. Any acute neurological condition should be treated without waiting for definitive biochemical confirmation.PMID:38520815 | DOI:10.1016/j.ejpn.2024.02.013 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - March 23, 2024 Category: Neurology Authors: Gabrielle Dupuy Charles-Joris Roux R émi Barrois Apolline Imbard Cl ément Pontoizeau Marie Th érèse Dangles M élodie Aubart Jean-Baptiste Arnoux Diane Margoses Ana ïs Brassier Clothilde Marbach Claire-Marine B érat Eug énie Sarda Cyril Gitiaux Pas Source Type: research

Vitamin deficiencies in children: Lessons from clinical and neuroimaging findings
CONCLUSIONS: Acquired vitamin deficiencies may display reversible clinical symptoms mimicking inherited metabolic disorders. Some situations raise suspicion for diagnosis: concordant clinical presentation, suggestive neuroimaging findings, and/or biochemical evidence. Any acute neurological condition should be treated without waiting for definitive biochemical confirmation.PMID:38520815 | DOI:10.1016/j.ejpn.2024.02.013 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - March 23, 2024 Category: Neurology Authors: Gabrielle Dupuy Charles-Joris Roux R émi Barrois Apolline Imbard Cl ément Pontoizeau Marie Th érèse Dangles M élodie Aubart Jean-Baptiste Arnoux Diane Margoses Ana ïs Brassier Clothilde Marbach Claire-Marine B érat Eug énie Sarda Cyril Gitiaux Pas Source Type: research

NME6 as a potential biomarker and therapeutic target involved in immune infiltration for lung adenocarcinoma
CONCLUSION: The analysis showed that NME6 is a crucial prognostic factor for LUAD patients. NME6 regulates genes related to m6A modification and immune cells infiltration. Furthermore, NME6 could sever as a potential therapeutic target for LUAD.PMID:38517815 | DOI:10.3233/THC-231058 (Source: Technology and Health Care)
Source: Technology and Health Care - March 22, 2024 Category: Medical Devices Authors: Linjie Luo Ying Li Lin Zhang Lijie Yang Source Type: research

Differential analysis of transcriptome of psychrophilic bacteria under different culture temperatures
CONCLUSION: In F13-10 vs F13-5, the differential genes were mainly concentrated in 20 pathways such as ATP-binding cassette transport (ABC) transporters, thiamine metabolism and flagella assembly; In F13-25 vs F13-5, the differential genes are mainly concentrated in 20 pathways, such as (ABC) transporters, arginine and proline metabolism, two-component system and so on; In F13-25 vs F13-10, the differential genes are mainly concentrated in 20 pathways such as various types of glycan synthesis, two-component system and arginine metabolism.PMID:38517814 | DOI:10.3233/THC-231022 (Source: Technology and Health Care)
Source: Technology and Health Care - March 22, 2024 Category: Medical Devices Authors: Chun-Guang Xu Li-Xia Yang Rui Zhu Jie Zhang Yan Li Chun-Fang Chao Source Type: research

NME6 as a potential biomarker and therapeutic target involved in immune infiltration for lung adenocarcinoma
CONCLUSION: The analysis showed that NME6 is a crucial prognostic factor for LUAD patients. NME6 regulates genes related to m6A modification and immune cells infiltration. Furthermore, NME6 could sever as a potential therapeutic target for LUAD.PMID:38517815 | DOI:10.3233/THC-231058 (Source: Technology and Health Care)
Source: Technology and Health Care - March 22, 2024 Category: Medical Devices Authors: Linjie Luo Ying Li Lin Zhang Lijie Yang Source Type: research

Differential analysis of transcriptome of psychrophilic bacteria under different culture temperatures
CONCLUSION: In F13-10 vs F13-5, the differential genes were mainly concentrated in 20 pathways such as ATP-binding cassette transport (ABC) transporters, thiamine metabolism and flagella assembly; In F13-25 vs F13-5, the differential genes are mainly concentrated in 20 pathways, such as (ABC) transporters, arginine and proline metabolism, two-component system and so on; In F13-25 vs F13-10, the differential genes are mainly concentrated in 20 pathways such as various types of glycan synthesis, two-component system and arginine metabolism.PMID:38517814 | DOI:10.3233/THC-231022 (Source: Technology and Health Care)
Source: Technology and Health Care - March 22, 2024 Category: Medical Devices Authors: Chun-Guang Xu Li-Xia Yang Rui Zhu Jie Zhang Yan Li Chun-Fang Chao Source Type: research

NME6 as a potential biomarker and therapeutic target involved in immune infiltration for lung adenocarcinoma
CONCLUSION: The analysis showed that NME6 is a crucial prognostic factor for LUAD patients. NME6 regulates genes related to m6A modification and immune cells infiltration. Furthermore, NME6 could sever as a potential therapeutic target for LUAD.PMID:38517815 | DOI:10.3233/THC-231058 (Source: Technology and Health Care)
Source: Technology and Health Care - March 22, 2024 Category: Medical Devices Authors: Linjie Luo Ying Li Lin Zhang Lijie Yang Source Type: research

Differential analysis of transcriptome of psychrophilic bacteria under different culture temperatures
CONCLUSION: In F13-10 vs F13-5, the differential genes were mainly concentrated in 20 pathways such as ATP-binding cassette transport (ABC) transporters, thiamine metabolism and flagella assembly; In F13-25 vs F13-5, the differential genes are mainly concentrated in 20 pathways, such as (ABC) transporters, arginine and proline metabolism, two-component system and so on; In F13-25 vs F13-10, the differential genes are mainly concentrated in 20 pathways such as various types of glycan synthesis, two-component system and arginine metabolism.PMID:38517814 | DOI:10.3233/THC-231022 (Source: Technology and Health Care)
Source: Technology and Health Care - March 22, 2024 Category: Medical Devices Authors: Chun-Guang Xu Li-Xia Yang Rui Zhu Jie Zhang Yan Li Chun-Fang Chao Source Type: research

NME6 as a potential biomarker and therapeutic target involved in immune infiltration for lung adenocarcinoma
CONCLUSION: The analysis showed that NME6 is a crucial prognostic factor for LUAD patients. NME6 regulates genes related to m6A modification and immune cells infiltration. Furthermore, NME6 could sever as a potential therapeutic target for LUAD.PMID:38517815 | DOI:10.3233/THC-231058 (Source: Technology and Health Care)
Source: Technology and Health Care - March 22, 2024 Category: Medical Devices Authors: Linjie Luo Ying Li Lin Zhang Lijie Yang Source Type: research

Differential analysis of transcriptome of psychrophilic bacteria under different culture temperatures
CONCLUSION: In F13-10 vs F13-5, the differential genes were mainly concentrated in 20 pathways such as ATP-binding cassette transport (ABC) transporters, thiamine metabolism and flagella assembly; In F13-25 vs F13-5, the differential genes are mainly concentrated in 20 pathways, such as (ABC) transporters, arginine and proline metabolism, two-component system and so on; In F13-25 vs F13-10, the differential genes are mainly concentrated in 20 pathways such as various types of glycan synthesis, two-component system and arginine metabolism.PMID:38517814 | DOI:10.3233/THC-231022 (Source: Technology and Health Care)
Source: Technology and Health Care - March 22, 2024 Category: Medical Devices Authors: Chun-Guang Xu Li-Xia Yang Rui Zhu Jie Zhang Yan Li Chun-Fang Chao Source Type: research

How Can We Interpret the Unexpected Results in Two Pilot Trials Comparing Thiamine to Placebo after Cardiac Arrest?
Patients managed in the ICU following cardiac arrest suffer from multiple complications, including brain ischaemia resulting from reperfusion injury, circulatory failure and the risk of multiorgan failure [1]. To date, management has been largely supportive, with common ICU interventions aimed at normalising circulation, preventing secondary insults and employing neuroprognostication through a delayed multimodal approach [2]. A common characteristic of these patients is early lactatemia, which relates to whole-body ischaemia occurring during cardiac arrest. (Source: Resuscitation)
Source: Resuscitation - March 22, 2024 Category: Emergency Medicine Authors: Markus B Skrifvars Tags: Editorial Source Type: research

Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi
The objective of this report was to describe such a case.METHODS: An 82-year-old woman with advanced cervical cancer was admitted for palliative care because of progressive disease. One month after admission, she developed myoclonus on the left side, difficulty speaking, slurred speech, and drooping of the left corner of the mouth, with no consciousness disturbance. She also developed nausea and complained of decreased dietary intake for more than 2 weeks.RESULTS: The patient's thiamine level, which had been measured 2 weeks earlier, was 27 ng/ml, which was below the normal range, and 100 mg of thiamine was administered in...
Source: Palliative and Supportive Care - March 20, 2024 Category: Palliative Care Authors: Eriko Hayashi Tetsuya Matuura Junko Takano Kaori Morofushi Kaori Toriizuka Hideki Onishi Source Type: research

Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi
The objective of this report was to describe such a case.METHODS: An 82-year-old woman with advanced cervical cancer was admitted for palliative care because of progressive disease. One month after admission, she developed myoclonus on the left side, difficulty speaking, slurred speech, and drooping of the left corner of the mouth, with no consciousness disturbance. She also developed nausea and complained of decreased dietary intake for more than 2 weeks.RESULTS: The patient's thiamine level, which had been measured 2 weeks earlier, was 27 ng/ml, which was below the normal range, and 100 mg of thiamine was administered in...
Source: Palliative and Supportive Care - March 20, 2024 Category: Palliative Care Authors: Eriko Hayashi Tetsuya Matuura Junko Takano Kaori Morofushi Kaori Toriizuka Hideki Onishi Source Type: research

Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi
The objective of this report was to describe such a case.METHODS: An 82-year-old woman with advanced cervical cancer was admitted for palliative care because of progressive disease. One month after admission, she developed myoclonus on the left side, difficulty speaking, slurred speech, and drooping of the left corner of the mouth, with no consciousness disturbance. She also developed nausea and complained of decreased dietary intake for more than 2 weeks.RESULTS: The patient's thiamine level, which had been measured 2 weeks earlier, was 27 ng/ml, which was below the normal range, and 100 mg of thiamine was administered in...
Source: Palliative and Supportive Care - March 20, 2024 Category: Palliative Care Authors: Eriko Hayashi Tetsuya Matuura Junko Takano Kaori Morofushi Kaori Toriizuka Hideki Onishi Source Type: research