Proceedings of the Canadian Society for Exercise Physiology Annual General Meeting: CSEP 2020 Online! Enhancing our Performance, Keeping our Connections
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 11 (Suppl. 3), Page S285-S325, November 2020. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - November 16, 2020 Category: Physiology Source Type: research

Correction: Effect of exercise intensity on postprandial lipemia, markers of oxidative stress, and endothelial function after a high-fat meal
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - November 5, 2020 Category: Physiology Authors: Renata Lopes Kr üger Bruno Costa Teixeira Juliano Boufleur Farinha Rodrigo Cauduro Oliveira Macedo Francesco Pinto Boeno Anderson Rech Pedro Lopez Ronei Silveira Pinto Alvaro Reischak-Oliveira Source Type: research

Dissemination and implementation of national physical activity, sedentary behaviour, and/or sleep guidelines among community-dwelling adults aged 18 years and older: a systematic scoping review and suggestions for future reporting and research
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10 (Suppl. 2), Page S258-S283, October 2020. Strategies for dissemination (purposive distribution of a guideline to specific audiences) and implementation (actions to support the general public in meeting guideline recommendations/behavioural benchmarks) of national movement guidelines (physical activity (PA), sedentary behaviour, and sleep) have yet to be synthesized. The purpose of this systematic scoping review was to identify strategies for dissemination and implementation of national PA, sedentary behaviour, and/or sleep guidelines among community-dwelling...
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: J.R. Tomasone K.D. Kauffeldt T.L. Morgan K.W. Magor A.E. Latimer-Cheung G. Faulkner A. Ross-White V. Poitras M.E. Kho R. Ross Source Type: research

A systematic review of compositional data analysis studies examining associations between sleep, sedentary behaviour, and physical activity with health outcomes in adults
In conclusion, these findings support the notion that the composition of movement across the entire 24-h day matters, and that recommendations for sleep, SED, and physical activity should be combined into a single public health guideline. (PROSPERO registration no.: CRD42019121641.) Novelty The 24-h movement behaviour compositi on is associated with a variety of health outcomes. Reallocating time into MVPA is favourably associated with health. Reallocating time out of SED is associated with favourable changes to mortality risk. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: Ian Janssen Anna E. Clarke Valerie Carson Jean-Philippe Chaput Lora M. Giangregorio Michelle E. Kho Veronica J. Poitras Robert Ross Travis J. Saunders Amanda Ross-White Sebastien F.M. Chastin Source Type: research

Sleep timing, sleep consistency, and health in adults: a systematic review
In conclusion, the available evidence supports that earlier sleep timing and regularity in sleep patterns with consistent bedtimes and wake-up times are favourably associated with healt h. (PROSPERO registration no.: CRD42019119534.) Novelty This is the first systematic review to examine the influence of sleep timing and sleep consistency on health outcomes. Later sleep timing and greater variability in sleep are both associated with adverse health outcomes in adults. Regularity i n sleep patterns with consistent bedtimes and wake-up times should be encouraged. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: Jean-Philippe Chaput Caroline Dutil Ryan Featherstone Robert Ross Lora Giangregorio Travis J. Saunders Ian Janssen Veronica J. Poitras Michelle E. Kho Amanda Ross-White Sarah Zankar Julie Carrier Source Type: research

Sleep duration and health in adults: an overview of systematic reviews
In conclusion, the available evidence su ggests that a sleep duration of 7–8 h per day is the one most favourably associated with health among adults and older adults. (PROSPERO registration no.: CRD42019119529.) Novelty This is the first overview of reviews that examines the influence of sleep duration on a wide range of health outcome s in adults. Seven to 8 h of sleep per day was most favourably associated with health. Effect modification by age was not evident. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: Jean-Philippe Chaput Caroline Dutil Ryan Featherstone Robert Ross Lora Giangregorio Travis J. Saunders Ian Janssen Veronica J. Poitras Michelle E. Kho Amanda Ross-White Julie Carrier Source Type: research

Sedentary behaviour and health in adults: an overview of systematic reviews
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10 (Suppl. 2), Page S197-S217, October 2020. The purpose of this overview of systematic reviews was to determine the relationship between different types and patterns of sedentary behaviour and selected health outcomes in adults and older adults. Five electronic databases were last searched in May, 2019, with a 10-year search limit. Included reviews met the a priori population (community-dwelling adults aged 18 years and older), intervention/exposure/comparator (various types and/or patterns of sedentary behaviour), and outcomes criteria. Eighteen systematic re...
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: Travis J. Saunders Travis McIsaac Kevin Douillette Nick Gaulton Stephen Hunter Ryan E. Rhodes Stephanie A. Prince Valerie Carson Jean-Philippe Chaput Sebastien Chastin Lora Giangregorio Ian Janssen Peter T. Katzmarzyk Michelle E. Kho Veronica J. Poitras K Source Type: research

Balance and functional training and health in adults: an overview of systematic reviews
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10 (Suppl. 2), Page S180-S196, October 2020. This overview of systematic reviews examined the effect of balance and functional strength training on health outcomes in adults aged 18 years or older, to inform the Canadian 24-hour Movement Guidelines. Four electronic databases were searched for systematic reviews published between January 2009 and May 2019. Eligibility criteria were determined a priori for population (community-dwelling adults), intervention (balance and functional training), comparator (no intervention or different types/doses), and outcomes (cr...
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: Emily Claire McLaughlin Rasha El-Kotob Jean-Philippe Chaput Ian Janssen Michelle E. Kho Veronica J. Poitras Robert Ross Amanda Ross-White Travis J. Saunders Catherine Sherrington Lora M. Giangregorio Source Type: research

Resistance training and health in adults: an overview of systematic reviews
The objective of this overview of systematic reviews was to determine the benefits and harms of resistance training (RT) on health outcomes in adults aged 18 years or older, compared with not participating in RT. Four electronic databases were searched in February 2019 for systematic reviews published in the past 10 years. Eligibility criteria were determined a priori for population (community dwelling adults), intervention (exclusively RT), comparator (no RT or different doses of RT), and health outcomes (critical: mortality, physical functioning, health-related quality of life, and adverse events; important: cardiovascul...
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: Rasha El-Kotob Matteo Ponzano Jean-Philippe Chaput Ian Janssen Michelle E. Kho Veronica J. Poitras Robert Ross Amanda Ross-White Travis J. Saunders Lora M. Giangregorio Source Type: research

Development and application of an outcome-centric approach for conducting overviews of reviews
We report our methodology in a PRISMA table. Across the 4 overviews, authors reviewed 1110 full texts; 45 were retained (low to high quality per AMSTAR 2), representing 950 primary studies, enrolling over 5 385 500 participants. Of 46 outcomes, we identified data for 35. Nineteen outcomes required>1 review (CCA range: 0% to 71.4%). Our outcome-centric overviews addressed unique aspects of overviews, including selection and quality assessment of included reviews, and overlap. Lessons learned included consistent application of methodological principles to minimize bias and optimize reporting transparency. No...
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: Michelle E. Kho Veronica J. Poitras Ian Janssen Jean-Philippe Chaput Travis J. Saunders Lora M. Giangregorio Jennifer R. Tomasone Amanda Ross-White Robert Ross Source Type: research

Optimal messaging of the Canadian 24-Hour Movement Guidelines for Adults aged 18 –64 years and Adults aged 65 years and older
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10 (Suppl. 2), Page S125-S150, October 2020. The Canadian 24-Hour Movement Guidelines for Adults aged 18 –64 years and Adults aged 65 years and older (“Guidelines”) integrate recommendations for physical activity, sedentary, and sleep behaviours. Given the novelty of these integrated Guidelines, it was important to consider messaging strategies that would be most effective in reaching Canadian ad ults. The purpose of this study was to examine optimal messaging of the Guidelines as it pertains to communication channels and messages. Representat...
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: Emma Faught Alexandra J. Walters Amy E. Latimer-Cheung Guy Faulkner Rebecca Jones Mary Duggan Tala Chulak-Bozzer Kirstin N. Lane Melissa C. Brouwers Jennifer R. Tomasone Source Type: research

Knowledge translation of the Canadian 24-Hour Movement Guidelines for Adults aged 18 –64 years and Adults aged 65 years or older: a collaborative movement guideline knowledge translation process
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10 (Suppl. 2), Page S103-S124, October 2020. Establishing a step-by-step process that provides practitioners with a blueprint for translating movement guidelines into action stands to optimize the investment in guideline development, improve guideline promotion and uptake, and ultimately enhance population health. The purpose of this paper is to describe how the Knowledge-to-Action framework and integrated knowledge translation were operationalized to systematically inform our knowledge translation (KT) efforts for the Canadian 24-Hour Movement Guidelines for A...
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: Jennifer R. Tomasone Stephanie M. Flood Amy E. Latimer-Cheung Guy Faulkner Mary Duggan Rebecca Jones Kirstin N. Lane Frances Bevington Julie Carrier Matt Dolf Kevin Doucette Emma Faught Madelaine Gierc Nicole Giouridis Reut Gruber Nora Johnston Kaitlyn D. Source Type: research

Canadian 24-Hour Movement Guidelines for Adults aged 18 –64 years and Adults aged 65 years or older: an integration of physical activity, sedentary behaviour, and sleep
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10 (Suppl. 2), Page S57-S102, October 2020. The Canadian Society for Exercise Physiology assembled a Consensus Panel representing national organizations, content experts, methodologists, stakeholders, and end-users and followed an established guideline development procedure to create the Canadian 24-Hour Movement Guidelines for Adults aged 18 –64 years and Adults aged 65 years or older: An Integration of Physical Activity, Sedentary Behaviour, and Sleep. These guidelines underscore the importance of movement behaviours across the whole 24-h day. The devel...
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: Robert Ross Jean-Philippe Chaput Lora M. Giangregorio Ian Janssen Travis J. Saunders Michelle E. Kho Veronica J. Poitras Jennifer R. Tomasone Rasha El-Kotob Emily C. McLaughlin Mary Duggan Julie Carrier Valerie Carson Sebastien F. Chastin Amy E. Latimer-C Source Type: research

Introduction to the Canadian 24-Hour Movement Guidelines for Adults aged 18 –64 years and Adults aged 65 years or older: an integration of physical activity, sedentary behaviour, and sleep
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10 (Suppl. 2), Page v-xi, October 2020. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Authors: Robert Ross Mark Tremblay Source Type: research

CSEP Special Supplement: Canadian 24-Hour Movement Guidelines for Adults aged 18 –64 years and Adults aged 65 years or older / Supplément spécial de la SCPE : Directives canadiennes en matière de mouvement sur 24 heures pour les adultes âgés de 18 à 64 ans et les adultes âgés de 65 ans et plus
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10 (Suppl. 2), Page iii-iii, October 2020. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - October 15, 2020 Category: Physiology Source Type: research

Correction: A multi-ingredient nutritional supplement enhances exercise training-related reductions in markers of systemic inflammation in healthy older men
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - September 27, 2020 Category: Physiology Authors: Kirsten E. Bell Tim Snijders Michael A. Zulyniak Dinesh Kumbhare Gianni Parise Adrian Chabowski Stuart M. Phillips Source Type: research

Correction: A multi-ingredient nutritional supplement enhances exercise training-related reductions in markers of systemic inflammation in healthy older men
Applied Physiology, Nutrition, and Metabolism, e-First Articles. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - September 27, 2020 Category: Physiology Authors: Kirsten E. Bell Tim Snijders Michael A. Zulyniak Dinesh Kumbhare Gianni Parise Adrian Chabowski Stuart M. Phillips Source Type: research

Aerobic exercise training attenuates detrimental effects of cigarette smoke exposure on peripheral muscle through stimulation of the Nrf2 pathway and cytokines: a time-course study in mice
Applied Physiology, Nutrition, and Metabolism, e-First Articles. Cigarette smoke (CS) exposure reduces skeletal muscle function; however, the mechanisms involved have been poorly investigated. The current study evaluated the temporal effects of aerobic exercise training on oxidant and antioxidant systems as well as inflammatory markers in skeletal muscle of mice exposed to CS. Mice were randomly allocated to control, exercise, smoke, and smoke+exercise groups and 3 time points (4, 8, and 12 weeks; n = 12 per group). Exercise training and CS exposure were performed for 30 min/day, twice a day, 5 days/week for 4, 8, and 12 w...
Source: Applied Physiology, Nutrition, and Metabolism - August 18, 2020 Category: Physiology Authors: Alessandra C. Toledo-Arruda Ivo Vieira de Sousa Neto Rodolfo P. Vieira Fl ávia A. Guarnier Agostinho Caleman-Neto Camila L. Suehiro Clarice R. Olivo Rubens Cecchini Carla M. Prado Chin J. Lin Jo ão Luiz Quaglioti Durigan Milton A. Martins Source Type: research

Examining the effects of applying ActiGraph low-frequency extension feature to analyze the sleeping behaviours of preschool-aged children
This study compares sleep outcome measures obtained using normal- and low-frequency extension (LFE) settings (Actilife). Forty-two children (aged 3 –6 years) were instructed to wear an ActiGraph GT3X+ accelerometer on their hip for 7 days, 24 h/day. Total sleep time (min), sleep efficiency (%), and number and cumulative length (min) of awakening were used to compare the settings. Results suggest that the LFE setting results in significant but relatively small reductions in the sleep metrics of children. Trial registration no.: clincialtrials.gov (ID no. NCT02223234) Novelty LFE setting, available through ActiGraph, e...
Source: Applied Physiology, Nutrition, and Metabolism - August 11, 2020 Category: Physiology Authors: Hannah J. Coyle-Asbil Becky Breau David W.L. Ma Jess Haines Lori Ann Vallis Source Type: research

Healthy brain, healthy life: a review of diet and exercise interventions to promote brain health and reduce Alzheimer ’s disease risk
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10, Page 1055-1065, October 2020. With the world ’s population aging at a rapid rate, the prevalence of Alzheimer’s disease (AD) has significantly increased. These statistics are alarming given recent evidence that a third of dementia cases may be preventable. The role of lifestyle factors, such as diet and exercise, can directly alter the ris k of disease development. However, an understanding of the effectiveness of dietary patterns and exercise strategies to reduce AD risk or improve brain function is not fully understood. The aim of this review ...
Source: Applied Physiology, Nutrition, and Metabolism - July 26, 2020 Category: Physiology Authors: Bradley J. Baranowski Daniel M. Marko Rachel K. Fenech Alex J.T. Yang Rebecca E.K. MacPherson Source Type: research

Healthy brain, healthy life: a review of diet and exercise interventions to promote brain health and reduce Alzheimer ’s disease risk
Applied Physiology, Nutrition, and Metabolism, e-First Articles. With the world ’s population aging at a rapid rate, the prevalence of Alzheimer’s disease (AD) has significantly increased. These statistics are alarming given recent evidence that a third of dementia cases may be preventable. The role of lifestyle factors, such as diet and exercise, can directly alter the ris k of disease development. However, an understanding of the effectiveness of dietary patterns and exercise strategies to reduce AD risk or improve brain function is not fully understood. The aim of this review is to discuss the effects of die...
Source: Applied Physiology, Nutrition, and Metabolism - July 26, 2020 Category: Physiology Authors: Bradley J. Baranowski Daniel M. Marko Rachel K. Fenech Alex J.T. Yang Rebecca E.K. MacPherson Source Type: research

Comparison of methodologies used to define the protein quality of human foods and support regulatory claims
Applied Physiology, Nutrition, and Metabolism, e-First Articles. Protein quality (PQ) is the capacity of a protein to meet the amino acid (AA) requirements of an individual. There are several methodologies for determining the PQ of foods. The protein efficiency ratio is an animal growth bioassay. The protein-digestibility-corrected AA score considers the AA requirements of a reference population, and the true nitrogen digestibility coefficient for each ingredient. The digestible indispensable AA score is based on true ileal AA digestibility and better represents bioavailability of AAs. In vitro techniques for assessment of...
Source: Applied Physiology, Nutrition, and Metabolism - July 23, 2020 Category: Physiology Authors: Wilfredo D. Mansilla Christopher P.F. Marinangeli Cara Cargo-Froom Adam Franczyk James D. House Rajavel Elango Daniel A. Columbus Elijah Kiarie Mike Rogers Anna K. Shoveller Source Type: research

Correction: Effects of high-velocity resistance training and creatine supplementation in untrained healthy aging males
Applied Physiology, Nutrition, and Metabolism, e-First Articles. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - July 21, 2020 Category: Physiology Authors: Patrick Bernat Darren G. Candow Karolina Gryzb Sara Butchart Brad J. Schoenfeld Paul Bruno Source Type: research

Sex and light physical activity impact popliteal, but not brachial artery flow-mediated dilation in physically active young adults
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. When controlling for baseline diameter, males have greater brachial flow-mediated dilation (BA-FMD) responses than females. It is unclear whether sex differences in baseline diameter also influences popliteal FMD (POP-FMD), which may be impacted by cardiorespiratory fitness and physical activity levels. We hypothesized that males would exhibit greater BA-FMD and POP-FMD when allometrically scaled to baseline diameter. FMD (ultrasonography), cardiorespiratory fitness (indirect calorimetry), and objectively measured physical activity were assessed in males (n = 1...
Source: Applied Physiology, Nutrition, and Metabolism - July 20, 2020 Category: Physiology Authors: Jarrett A. Johns Myles W. O ’Brien Amanda Bungay Derek S. Kimmerly Source Type: research

Dietary intake, clinical-nutritional status, and homocysteine in hemodialysis subjects: the mediating role of inflammation (NUGE-HD study)
In conclusion, the ratio of saturated and polyunsaturated fatty ac ids had a direct effect on plasma Hcys, whereas inflammation had a direct and mediating effect on the relationship between Hcys and diabetes mellitus in HD subjects. Novelty In end-stage renal disease, CRP influences plasma Hcys directly and also indirectly through its mediating effect. The quantit y and quality of dietary fatty acids influence plasma Hcys concentrations in HD subjects. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - July 16, 2020 Category: Physiology Authors: Karla Pereira Balbino Leidjaira Lopes Juvanhol Aline Lage Wendling Luciane Domingos Marota Jaqueline Beatriz Silva Costa Josefina Bressan Helen Hermana Miranda Hermsdorff Source Type: research

Growing up strong: The importance of physical, mental, and emotional strength during childhood and adolescence with focus on dietary factors
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10, Page 1071-1080, October 2020. Childhood and adolescence are critical time periods for growth and development. Given the current physical and psychological health concerns affecting United States youth, an emerging area of interest exists supporting the importance of physical and psychological aspects of strength for health, resilience, and well-being through these life stages. This synopsis highlights the key concepts that were presented within the 2018 Strength Summit conference, entitled The Role of Strength in Optimal Health and Well-being. During the co...
Source: Applied Physiology, Nutrition, and Metabolism - July 9, 2020 Category: Physiology Authors: Heather J. Leidy Jess A. Gwin Source Type: research

Growing up strong: The importance of physical, mental, and emotional strength during childhood and adolescence with focus on dietary factors
Applied Physiology, Nutrition, and Metabolism, e-First Articles. Childhood and adolescence are critical time periods for growth and development. Given the current physical and psychological health concerns affecting United States youth, an emerging area of interest exists supporting the importance of physical and psychological aspects of strength for health, resilience, and well-being through these life stages. This synopsis highlights the key concepts that were presented within the 2018 Strength Summit conference, entitled The Role of Strength in Optimal Health and Well-being. During the conference, strength was broadly d...
Source: Applied Physiology, Nutrition, and Metabolism - July 9, 2020 Category: Physiology Authors: Heather J. Leidy Jess A. Gwin Source Type: research

Correction: Acute effects of exercise intensity on subsequent substrate utilisation, appetite, and energy balance in men and women
Applied Physiology, Nutrition, and Metabolism, e-First Articles. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - July 1, 2020 Category: Physiology Authors: Ghalia Shamlan Paul Bech M. Denise Robertson Adam L. Collins Source Type: research

Age and sex-related decline of muscle strength across the adult lifespan: a scoping review of aggregated data
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Muscle strength is sex-related and declines with advancing age; yet, a comprehensive comparative evaluation of age-related strength loss in human females and males has not been undertaken. To do so, segmented piecewise regression analysis was performed on aggregated data from studies published from 1990 to 2018 and are available in CINAHL, EMBASE, MEDLINE, and PsycINFO databases. The search identified 5613 articles that were reviewed for physical assessment results stratified by sex and age. Maximal isometric and isokinetic 60 °·s−1 knee extens...
Source: Applied Physiology, Nutrition, and Metabolism - June 29, 2020 Category: Physiology Authors: E.M.K. Haynes N.A. Neubauer K.M.D. Cornett B.P. O ’Connor G.R. Jones J.M. Jakobi Source Type: research

Micronutrient fortification of caffeinated energy drinks and supplemented foods marketed in Canada
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10, Page 1178-1183, October 2020. To examine the micronutrient content of discretionarily fortified products marketed under Canada ’s current regulations, we conducted an in-store and online search for products granted Temporary Marketing Authorizations in 2018. We located 129 caffeinated energy drinks and 98 other beverage products. Most were fortified at levels well below permitted maximums, but 82.2% of energy drinks and 3 5.7% of other beverage products contained nutrients above 100% of Daily Values, suggesting that current fortification practices are...
Source: Applied Physiology, Nutrition, and Metabolism - June 25, 2020 Category: Physiology Authors: Rehona Zamani Valerie Tarasuk Source Type: research

Micronutrient fortification of caffeinated energy drinks and supplemented foods marketed in Canada
Applied Physiology, Nutrition, and Metabolism, e-First Articles. To examine the micronutrient content of discretionarily fortified products marketed under Canada ’s current regulations, we conducted an in-store and online search for products granted Temporary Marketing Authorizations in 2018. We located 129 caffeinated energy drinks and 98 other beverage products. Most were fortified at levels well below permitted maximums, but 82.2% of energy drinks and 3 5.7% of other beverage products contained nutrients above 100% of Daily Values, suggesting that current fortification practices are largely gratuitous. Novelty The...
Source: Applied Physiology, Nutrition, and Metabolism - June 25, 2020 Category: Physiology Authors: Rehona Zamani Valerie Tarasuk Source Type: research

Lipid droplets are both highly oxidized and Plin2-covered in hepatocytes of diet-induced obese mice
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Chronic high-fat diet feeding is associated with obesity and accumulation of fat in the liver, leading to the development of insulin resistance and nonalcoholic fatty liver disease. This condition is characterized by the presence of a high number of intrahepatic lipid droplets (LDs), with changes in the perilipin pattern covering them. This work aimed to describe the distribution of perilipin (Plin) 2, an LD-associated protein involved in neutral lipid storage, and Plin5, which favors lipid oxidation in LD, and to evaluate lipid peroxidation through live-cell v...
Source: Applied Physiology, Nutrition, and Metabolism - June 25, 2020 Category: Physiology Authors: Diego Nocetti Alejandra Espinosa Francisco Pino-De la Fuente Camila Sacrist án Jos é Luis Bucarey Paulina Ruiz Rodrigo Valenzuela Rapha ël Chouinard-Watkins In és Pepper Rodrigo Troncoso Luis Puente Source Type: research

Iron status is associated with worker productivity, independent of physical effort in Indian tea estate workers
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Iron deficiency is the most common nutrient deficiency in the world, affecting roughly 40% of women in nonindustrialized countries. Iron is the essential element in hemoglobin, the major carrier of blood oxygen and oxidative metabolism that supports physical and cognitive performance. The relationship between iron and physical work capacity suggests that iron deficient individuals could experience reduced work output. Participants were 138 experienced tea pluckers aged 18 –55 years from the Panighatta Tea Estate in Darjeeling District of northern West Ben...
Source: Applied Physiology, Nutrition, and Metabolism - June 24, 2020 Category: Physiology Authors: Mia M. Blakstad Julie E.H. Nevins Sudha Venkatramanan Eric M. Przybyszewski Jere D. Haas Source Type: research

Hyperbaric oxygen and focused rehabilitation program: a feasibility study in improving upper limb motor function after stroke
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Neuroplasticity and recovery after stroke can be enhanced by a rehabilitation program pertinent to upper limb motor function exercise and mental imagery (EMI) as well as hyperbaric oxygen therapy (HBOT). We assessed feasibility and safety of the combined approach utilizing both HBOT and EMI, and to derive preliminary estimates of its efficacy. In this randomized controlled trial, 27 patients with upper extremity hemiparesis at 3 –48 months after stroke were randomized to receive either a complementary rehabilitation program of HBOT-EMI (intervention group...
Source: Applied Physiology, Nutrition, and Metabolism - June 23, 2020 Category: Physiology Authors: S. Schiavo D. Richardson D. Santa Mina S. Buryk-Iggers J. Uehling J. Carroll H. Clarke C. Djaiani M. Gershinsky R. Katznelson Source Type: research

Caloric restriction-induced weight loss with a high-fat diet does not fully recover visceral adipose tissue inflammation in previously obese C57BL/6 mice
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Caloric restriction (CR) reduces body weight and systemic inflammation, but the effects on adipose tissue under dietary lipid overload are controversial. We evaluated the effects of CR-induced weight loss with a high-fat diet on adipose tissue inflammation of obese mice. Male mice were assigned into low-fat diet (LF) and high-fat diet (HF) groups. After 8 weeks, the mice in the HF group were reassigned for another 7 weeks into the following 3 conditions: (i) kept in the HF condition; (ii) changed to low-fat diet ad libitum (LFAL); and (iii) changed to high-fat ...
Source: Applied Physiology, Nutrition, and Metabolism - June 23, 2020 Category: Physiology Authors: M.O.M. Rodrigues P.H. Evangelista-Silva N.N. Neves L.G. Moreno C.S. Santos K.L.S. Rocha V.O. Ottone B. Batista-da-Silva M.F. Dias-Peixoto F.C. Magalh ães E.A. Esteves Source Type: research

Associations between physical activity, sedentary behavior, and urinary oxidized guanine in colorectal cancer patients: results from the ColoCare Study
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. To determine associations between physical activity (PA), sedentary behavior (SB), and oxidative stress in colorectal cancer patients, ColoCare Study participants in Germany wore an accelerometer 6 and/or 12 months after surgery. Spearman partial correlations were used to assess associations between PA and urinary concentrations of oxidized guanine, a validated marker of oxidative stress. There were no significant associations between PA or SB and oxidized guanine in n = 76 measurements (ng/mg creatinine; r = 0.03, p = 0.76 for PA, r = –0.05, p = 0.69 for...
Source: Applied Physiology, Nutrition, and Metabolism - June 22, 2020 Category: Physiology Authors: Richard Viskochil Biljana Gigic Tengda Lin Stephanie Skender J ürgen Böhm Petra Schrotz-King Karen Steindorf Robert Owen Jane C. Figueiredo Christopher I. Li Erin M. Siegel Sheetal Hardikar David Shibata Adetunji T. Toriola Martin Schneider Alexis Ulric Source Type: research

Cardiac rehabilitation is associated with greater improvements in psychological health following coronary artery bypass graft surgery when compared with percutaneous coronary intervention
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Following coronary revascularization, patients treated with coronary artery bypass graft surgery (CABG) have lower risk of major adverse cardiovascular events when compared with those treated with percutaneous coronary intervention (PCI). We compared changes in cardiovascular risk factors, such as psychological and cardiometabolic health indicators, among patients who completed cardiac rehabilitation (CR) following CABG and PCI. Longitudinal records of 278 patients who completed an outpatient CR program following CABG or PCI were analyzed. We compared changes i...
Source: Applied Physiology, Nutrition, and Metabolism - June 16, 2020 Category: Physiology Authors: Matthew Montesano Jennifer L. Reed Heather E. Tulloch Andrew L. Pipe Tasuku Terada Source Type: research

Examining the decay in serum ferritin following intravenous iron infusion: a retrospective cohort analysis of Olympic sport female athletes
Applied Physiology, Nutrition, and Metabolism,Volume 45, Issue 10, Page 1174-1177, October 2020. The long-term decay rate of serum ferritin post-iron infusion in athletic populations is currently unknown. Here, we modelled the decay rate of serum ferritin in female athletes after an intravenous iron infusion (n = 22). The post-infusion serum ferritin response and the rate of decay was highly variable between athletes; however, we demonstrate that follow-up blood testing at 1 (154 μg/L; 77–300 μg/L) and 6 months (107 μg/L; 54–208 μg/L) post-infusion is appropriate to observe treatment efficacy and ef...
Source: Applied Physiology, Nutrition, and Metabolism - June 15, 2020 Category: Physiology Authors: Alannah K.A. McKay Paul S.R. Goods Martyn J. Binnie Carmel Goodman Peter Peeling Source Type: research

Examining the decay in serum ferritin following intravenous iron infusion: a retrospective cohort analysis of Olympic sport female athletes
Applied Physiology, Nutrition, and Metabolism, e-First Articles. The long-term decay rate of serum ferritin post-iron infusion in athletic populations is currently unknown. Here, we modelled the decay rate of serum ferritin in female athletes after an intravenous iron infusion (n = 22). The post-infusion serum ferritin response and the rate of decay was highly variable between athletes; however, we demonstrate that follow-up blood testing at 1 (154 μg/L; 77–300 μg/L) and 6 months (107 μg/L; 54–208 μg/L) post-infusion is appropriate to observe treatment efficacy and effectiveness. Novelty Female athl...
Source: Applied Physiology, Nutrition, and Metabolism - June 15, 2020 Category: Physiology Authors: Alannah K.A. McKay Paul S.R. Goods Martyn J. Binnie Carmel Goodman Peter Peeling Source Type: research

Low-volume acute multi-joint resistance exercise elicits a circulating brain-derived neurotrophic factor response but not a cathepsin B response in well-trained men
This study examined if acute multi-joint resistance exercises (RE; back squat, bench press, and deadlift) to volitional failure elicited a postexercise increase in the circulating response of biomarkers associated with neuroprotection. Thirteen males (age: 24.5 ± 3.8 years, body mass: 84.01 ± 15.44 kg, height: 173.43 ± 8.57 cm, training age: 7.1 ± 4.2 years) performed 4 sets to failure at 80% of a 1-repetition maximum on the squat, bench press, and deadlift in successive weeks. The measured biomarkers were brain-derived neurotrophic factor (BDNF), insu lin-like growth factor 1 (IGF-1), cathepsin...
Source: Applied Physiology, Nutrition, and Metabolism - June 12, 2020 Category: Physiology Authors: Trevor K. Johnson Daniel J. Belcher Colby A. Sousa Joseph P. Carzoli Nishant P. Visavadiya Andy V. Khamoui Michael Whitehurst Michael C. Zourdos Source Type: research

Anxiolytic and antioxidant effects of Euterpe oleracea Mart. (a çaí) seed extract in adult rat offspring submitted to periodic maternal separation
In conclusion, ASE treatment has an anti-anxiety effect in rats submitted to PMS by reducing hypothalamic–pituitary–adrenal axis reactivity and increasing th e nitric oxide (NO)–brain-derived neurotrophic factor (BDNF)–TRKB pathway and antioxidant defense in the central nervous system. Novelty ASE has anti-anxiety and antioxidant effects in early-life stress. ASE reduces hypothalamic–pituitary–adrenal axis reactivity. The anxiolytic effect of AS E may involve activation of the NO–BDNF–TRKB pathway in the central nervous system. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - June 9, 2020 Category: Physiology Authors: Graziele Freitas de Bem Anicet Okinga Dayane Teixeira Ognibene Cristiane Aguiar da Costa Izabelle Barcellos Santos Ricardo Andrade Soares Dafne Lopes Beserra Silva Ana Paula Machado da Rocha Jemima Isnardo Fernandes Mabel Carneiro Fraga Cl áudio Carneiro Source Type: research

PGC-1 α-mediated regulation of mitochondrial function and physiological implications
Applied Physiology, Nutrition, and Metabolism, e-First Articles. The majority of human energy metabolism occurs in skeletal muscle mitochondria emphasizing the importance of understanding the regulation of myocellular mitochondrial function. The transcriptional co-activator peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 α) has been characterized as a major factor in the transcriptional control of several mitochondrial components. Thus, PGC-1α is often described as a master regulator of mitochondrial biogenesis as well as a central player in regulating the antioxidant defense. Howeve...
Source: Applied Physiology, Nutrition, and Metabolism - June 8, 2020 Category: Physiology Authors: Jens Frey Halling Henriette Pilegaard Source Type: research

Female Athlete Triad Coalition cumulative risk assessment tool: proposed alternative scoring strategies
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. We (i) identified alternative scoring strategies for the Female Athlete Triad Coalition cumulative risk assessment (CRA) tool to be utilized when particular risk factors (bone mineral density (BMD), oligomenorrhea/amenorrhea) cannot be determined; (ii) objectively defined dietary restriction for use in the CRA tool; and (iii) explored proxy measures of energy deficiency. This cross-sectional investigation of exercising women (n = 166) utilized an existing database derived from multiple studies designed to assess health, exercise, and menstrual function. Data fr...
Source: Applied Physiology, Nutrition, and Metabolism - June 5, 2020 Category: Physiology Authors: Kristen J. Koltun Nancy I. Williams Mary Jane De Souza Source Type: research

The accurate prediction of sweat rate from energy expenditure and air temperature: a proof-of-concept study
This study demonstrates the feasibility of accurately predicting SR from energy expenditure and air temperature alone. Novelty Results demonstrate that accurate runner SR prediction is possible with knowledge of only energy expenditure and air temperature. SR prediction error was smaller than scale weighing error in 85% of observations. Accurate runner SR prediction could help mitigate the common risks of over- and under-drinking. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - June 4, 2020 Category: Physiology Authors: Kurt J. Sollanek Mia Liu Andrei Carballo Aaron R. Caldwell Samuel N. Cheuvront Source Type: research

Nutrition interventions in populations with mental health conditions: a scoping review
Applied Physiology, Nutrition, and Metabolism, e-First Articles. Nutrition is a modifiable factor for intervention in mental disorders. This scoping review characterized nutrition intervention research in mental disorders. A 3-category framework characterized nutrition interventions: Guide (e.g., counselling), Provide (e.g., food provisions), and Add (e.g., supplementation). Nutrition interventions were classified as single-component (e.g., Guide) or complex (e.g., Guide-Provide). Sixty-nine trials met inclusion criteria, 96% were randomized controlled trials. Most commonly diagnosed mental disorders were depressive disord...
Source: Applied Physiology, Nutrition, and Metabolism - June 3, 2020 Category: Physiology Authors: Stephana J. Cherak Kirsten M. Fiest Laura VanderSluis Carlota Basualdo-Hammond Diane L. Lorenzetti Sue Buhler Janet Stadnyk Lorna Driedger Lori Hards Leah Gramlich Tanis R. Fenton Source Type: research