Trends in diagnostic tests ordered for children: a retrospective analysis of 1.7 million laboratory test requests in Oxfordshire, UK from 2005 to 2019
CONCLUSIONS: After an initial decline, laboratory test use by children in Oxfordshire demonstrated an apparent increase since 2012. Test use increased in outpatient and general practice settings, however remained steady in inpatient settings. Further research should examine the root causes and implications for test increases, and whether these increases are warranted. We encourage clinicians to consider the individual and systemic implications of performing blood tests in children.PMID:37949643 | DOI:10.1136/archdischild-2023-325550 (Source: cmaj)
Source: cmaj - November 10, 2023 Category: General Medicine Authors: Elizabeth T Thomas Diana R Withrow Brian Shine Peter Gill Rafael Perera Carl Heneghan Source Type: research
Effects of biodegradable and conventional microplastics on the intestine, intestinal community composition, and metabolic levels in tilapia (Oreochromis mossambicus)
Aquat Toxicol. 2023 Nov 3;265:106745. doi: 10.1016/j.aquatox.2023.106745. Online ahead of print.ABSTRACTDespite growing interest in conventional microplastics (CMPs) and their toxicological effects on aquatic species, little is known about biodegradable microplastics (BMPs) and their corresponding implications for aquatic life. Here, tilapia (Oreochromis mossambicus) were semi-statically exposed for 14 days to the bio-based plastic polylactic acid (PLA, 100 μg/L, 2.52 ± 0.46 μm) and the petroleum-based plastic polyvinyl chloride (PVC, 100 μg/L, 1.58 ± 0.36 μm). The results showed that ingesting the above two types of...
Source: Aquatic Toxicology - November 9, 2023 Category: Toxicology Authors: Ruiqi Bao Zhiruo Cheng Licheng Peng Tariq Mehmood Liu Gao Shengchi Zhuo Li Wang Yuanyuan Su Source Type: research
Effects of biodegradable and conventional microplastics on the intestine, intestinal community composition, and metabolic levels in tilapia (Oreochromis mossambicus)
Aquat Toxicol. 2023 Nov 3;265:106745. doi: 10.1016/j.aquatox.2023.106745. Online ahead of print.ABSTRACTDespite growing interest in conventional microplastics (CMPs) and their toxicological effects on aquatic species, little is known about biodegradable microplastics (BMPs) and their corresponding implications for aquatic life. Here, tilapia (Oreochromis mossambicus) were semi-statically exposed for 14 days to the bio-based plastic polylactic acid (PLA, 100 μg/L, 2.52 ± 0.46 μm) and the petroleum-based plastic polyvinyl chloride (PVC, 100 μg/L, 1.58 ± 0.36 μm). The results showed that ingesting the above two types of...
Source: Aquatic Toxicology - November 9, 2023 Category: Toxicology Authors: Ruiqi Bao Zhiruo Cheng Licheng Peng Tariq Mehmood Liu Gao Shengchi Zhuo Li Wang Yuanyuan Su Source Type: research
The relationship between nutrition and micronutrients in healthy Turkish infants and young children
CONCLUSION: Micronutrients such as calcium, folic acid, iron, vitamin D, and iodine are critical in early fetal development from pregnancy onward. It is vital to raise awareness of this issue for mothers, starting from pregnancy, and for mothers to feed their babies more carefully in the first years of life.PMID:37940505 | DOI:10.1016/j.arcped.2023.08.013 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - November 8, 2023 Category: Pediatrics Authors: Hakan Onur Arzu Rahmanal ı Onur Özgür Aslan Source Type: research
The relationship between nutrition and micronutrients in healthy Turkish infants and young children
CONCLUSION: Micronutrients such as calcium, folic acid, iron, vitamin D, and iodine are critical in early fetal development from pregnancy onward. It is vital to raise awareness of this issue for mothers, starting from pregnancy, and for mothers to feed their babies more carefully in the first years of life.PMID:37940505 | DOI:10.1016/j.arcped.2023.08.013 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - November 8, 2023 Category: Pediatrics Authors: Hakan Onur Arzu Rahmanal ı Onur Özgür Aslan Source Type: research
Molecules, Vol. 28, Pages 7469: Recent Advances in Dietary Sources, Health Benefits, Emerging Encapsulation Methods, Food Fortification, and New Sensor-Based Monitoring of Vitamin B12: A Critical Review
ep Altintas
In this overview, the latest achievements in dietary origins, absorption mechanism, bioavailability assay, health advantages, cutting-edge encapsulation techniques, fortification approaches, and innovative highly sensitive sensor-based detection methods of vitamin B12 (VB12) were addressed. The cobalt-centered vitamin B is mainly found in animal products, posing challenges for strict vegetarians and vegans. Its bioavailability is highly influenced by intrinsic factor, absorption in the ileum, and liver reabsorption. VB12 mainly contributes to blood cell synthesis, cognitive function, and cardiovascular heal...
Source: Molecules - November 7, 2023 Category: Chemistry Authors: Seyed Mohammad Taghi Gharibzahedi Maryam Moghadam Jonas Amft Aysu Tolun Gauri Hasabnis Zeynep Altintas Tags: Review Source Type: research
Effect of blocking the haem synthesis pathway and weakening the haem synthesis pathway for sirohaem on the growth of and vitamin B < sub > 12 < /sub > synthesis in Ensifer adhaerens Casida A
Bioprocess Biosyst Eng. 2023 Nov 6. doi: 10.1007/s00449-023-02939-5. Online ahead of print.ABSTRACTTo block and weaken the bacterial branched VB12 synthetic metabolic pathway, homologous recombination technology was used to knock out the sirohaem synthase gene cysG located in the chromosome and the endogenous A plasmid of the Ensifer adhaerens Casida A strain, and the expression of the uroporphyrinogen III decarboxylase gene hemE was weakened by weak promoter substitution. The growth of the engineered strains and the production of VB12 and haem were analysed and measured in the engineered strains, aiming to provide a new s...
Source: Bioprocess and Biosystems Engineering - November 6, 2023 Category: Biomedical Engineering Authors: Yongheng Liu Yongyong Chang Qi Wang Wei Huang Cilang Ma Jianyu Su Source Type: research
Effect of blocking the haem synthesis pathway and weakening the haem synthesis pathway for sirohaem on the growth of and vitamin B < sub > 12 < /sub > synthesis in Ensifer adhaerens Casida A
Bioprocess Biosyst Eng. 2023 Nov 6. doi: 10.1007/s00449-023-02939-5. Online ahead of print.ABSTRACTTo block and weaken the bacterial branched VB12 synthetic metabolic pathway, homologous recombination technology was used to knock out the sirohaem synthase gene cysG located in the chromosome and the endogenous A plasmid of the Ensifer adhaerens Casida A strain, and the expression of the uroporphyrinogen III decarboxylase gene hemE was weakened by weak promoter substitution. The growth of the engineered strains and the production of VB12 and haem were analysed and measured in the engineered strains, aiming to provide a new s...
Source: Bioprocess and Biosystems Engineering - November 6, 2023 Category: Biomedical Engineering Authors: Yongheng Liu Yongyong Chang Qi Wang Wei Huang Cilang Ma Jianyu Su Source Type: research
Copper iodide nanoparticles supported on modified graphene-based nanocomposite catalyzed CO < sub > 2 < /sub > conversion into oxazolidinone derivatives
We report on the preparation of copper iodide nanoparticles (NPs) immobilized on vitamin B3-modified graphene (CuI/GO-VB) nanocomposite and its application for the synthesis of oxazolidinone compounds using a remarkable carboxylative cyclization method via the reaction of arylacetylene, aldehyde and benzylamine derivatives under an atmospheric pressure of CO2 gas. The CuI/GO-VB catalyst was prepared from graphene oxide (GO), vitamin B3 (VB) and CuI using a two-step procedure; firstly graphene-based composite (GO-VB) was synthesized by the reaction of GO and nicotinoyl chloride, followed by the immobilization of CuI NPs on ...
Source: Environmental Science and Pollution Research International - November 3, 2023 Category: Environmental Health Authors: Maryam Mirza-Aghayan Mahdi Alizadeh Rabah Boukherroub Source Type: research
Association between Vitamin B < sub > 6 < /sub > and Risk of Gastric Cancer: A Systematic Review and Meta-Analysis of Epidemiological Studies
In conclusion, there is not sufficient evidence to assume that vitamin B6 intake is associated with gastric cancer risk, which needs further confirmation.PMID:37904520 | DOI:10.1080/01635581.2023.2274134 (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - October 31, 2023 Category: Cancer & Oncology Authors: Cong Li Jianbo He Hongjuan Fu Hui Chang Source Type: research
Association between Vitamin B < sub > 6 < /sub > and Risk of Gastric Cancer: A Systematic Review and Meta-Analysis of Epidemiological Studies
In conclusion, there is not sufficient evidence to assume that vitamin B6 intake is associated with gastric cancer risk, which needs further confirmation.PMID:37904520 | DOI:10.1080/01635581.2023.2274134 (Source: Cancer Control)
Source: Cancer Control - October 31, 2023 Category: Cancer & Oncology Authors: Cong Li Jianbo He Hongjuan Fu Hui Chang Source Type: research
Association between Vitamin B < sub > 6 < /sub > and Risk of Gastric Cancer: A Systematic Review and Meta-Analysis of Epidemiological Studies
In conclusion, there is not sufficient evidence to assume that vitamin B6 intake is associated with gastric cancer risk, which needs further confirmation.PMID:37904520 | DOI:10.1080/01635581.2023.2274134 (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - October 31, 2023 Category: Cancer & Oncology Authors: Cong Li Jianbo He Hongjuan Fu Hui Chang Source Type: research
Nanomaterials for fluorescent detection of vitamin B < sub > 2 < /sub > : A review
Anal Biochem. 2023 Oct 17:115351. doi: 10.1016/j.ab.2023.115351. Online ahead of print.ABSTRACTVitamin B2 plays vital roles in maintaining human health. It is of tremendous significance to construct sensitive sensors of VB2. In this review, we first briefly presented the sensing mechanisms of fluorescent nanomaterials for sensing VB2. Subsequently, the advances of nanomaterials for fluorescent determination of VB2 were highlighted. And sensing performance of traditional approaches and fluorescent nanosensors was further compared. In last section, the challenges and perspectives concerning the topic were discussed.PMID:3785...
Source: Analytical Biochemistry - October 20, 2023 Category: Biochemistry Authors: Yanjuan Luo Yongming Guo Source Type: research
Review on Nutritional Potential of Underutilized Millets as a Miracle Grain
Curr Pharm Biotechnol. 2023 Oct 9. doi: 10.2174/0113892010248721230921093208. Online ahead of print.ABSTRACTThe current situation, which includes changes in eating habits, an increasing population, and the unrestricted use of natural resources, has resulted in a lack of resources that could be used to provide nourishing food to everyone. Natural plant resources are quickly being depleted, so it is necessary to consider new alternatives. In addition to the staple grains of rice and wheat, many other crops are being consumed that need to be utilized to their full potential and have the potential to replace the staple crops. ...
Source: Current Pharmaceutical Biotechnology - October 20, 2023 Category: Biotechnology Authors: Sonia Singh Himanshu Sharma Raghavan Ramankutty Sarada Ramaswamy Source Type: research
Nanomaterials for fluorescent detection of vitamin B < sub > 2 < /sub > : A review
Anal Biochem. 2023 Oct 17:115351. doi: 10.1016/j.ab.2023.115351. Online ahead of print.ABSTRACTVitamin B2 plays vital roles in maintaining human health. It is of tremendous significance to construct sensitive sensors of VB2. In this review, we first briefly presented the sensing mechanisms of fluorescent nanomaterials for sensing VB2. Subsequently, the advances of nanomaterials for fluorescent determination of VB2 were highlighted. And sensing performance of traditional approaches and fluorescent nanosensors was further compared. In last section, the challenges and perspectives concerning the topic were discussed.PMID:3785...
Source: Analytical Biochemistry - October 20, 2023 Category: Biochemistry Authors: Yanjuan Luo Yongming Guo Source Type: research
