Interactions between folate metabolism-related nutrients and polymorphisms on colorectal cancer risk: a case-control study in the Basque country
Eur J Nutr. 2024 Apr 23. doi: 10.1007/s00394-024-03371-5. Online ahead of print.ABSTRACTFolate-mediated one-carbon metabolism (FOCM) plays an important role in colorectal carcinogenesis. Previous studies have assessed the role of folate-mediated one-carbon metabolism (FOCM)-related gene-diet interaction in the aetiology of colorectal cancer (CRC), however, the results remained inconclusive. Thus, this study aimed to investigate dietary factors and genetic variants related to FOCM, as well as potential nutrient-gene and nutrient-lifestyle interactions, on CRC risk. This observational study included 229 patients diagnosed wi...
Source: Cancer Control - April 23, 2024 Category: Cancer & Oncology Authors: Sara Corchero-Palacios Iker Alegria-Lertxundi Marian M de Pancorbo Marta Arroyo-Izaga Source Type: research

Co-culturing Propionibacterium freudenreichii and Bifidobacterium animalis subsp. lactis improves short-chain fatty acids and vitamin B < sub > 12 < /sub > contents in soy whey
Food Microbiol. 2024 Aug;121:104525. doi: 10.1016/j.fm.2024.104525. Epub 2024 Mar 29.ABSTRACTThe lack of vitamin B12 in unprocessed plant-based foods can lead to health problems in strict vegetarians and vegans. The main aim of this study was to investigate the potential synergy of co-culturing Bifidobacterium animalis subsp. lactis and Propionibacterium freudenreichii in improving production of vitamin B12 and short-chain fatty acids in soy whey. Different strategies including mono-, sequential and simultaneous cultures were adopted. Growth, short-chain fatty acids and vitamin B12 were assessed throughout the fermentation...
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Ricco Tindjau Jian-Yong Chua Shao-Quan Liu Source Type: research

Monitoring the utilization and effectiveness of Iron and Vitamin D supplementations program and its predictive factors in high schools ’ girls in Qom, Iran
Conclusion:The inadequate and incomplete rate of IVDSP in Qom was high and more than 60% of distributed supplementations have been wasted. Our results showed that students who were participated in educational orientation classes were more successful and eager in iron and vitamin D3 consumption.  Therefore, it is recommended to increase interventions at individual, interpersonal, intra-organizational and inter-organizational levels in order to fully support the program and ultimately increase the efficiency of the program.  (Source: Journal of Preventive Medicine and Hygiene)
Source: Journal of Preventive Medicine and Hygiene - April 15, 2024 Category: International Medicine & Public Health Authors: Abolfazl Mohammadbeigi, Dr Source Type: research

Vitamin B < sub > 6 < /sub > alleviates chronic sleep deprivation-induced hippocampal ferroptosis through CBS/GSH/GPX4 pathway
Biomed Pharmacother. 2024 Apr 9;174:116547. doi: 10.1016/j.biopha.2024.116547. Online ahead of print.ABSTRACTSeveral studies have found that sleep deprivation (SD) can lead to neuronal ferroptosis and affect hippocampal function. However, there are currently no effective interventions. Vitamin B6 is a co-factor for key enzymes in the transsulfuration pathway which is critical for maintaining cell growth in the presence of cysteine deprivation. The results showed that SD inhibited cystine-glutamate antiporter light chain subunit xCT protein expression and caused cysteine deficiency, which reduced the synthesis of the glutat...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 10, 2024 Category: Drugs & Pharmacology Authors: Man Yuan Feng Wang Tieqiang Sun Xiangyu Bian Yuxian Zhang Changjiang Guo Lixia Yu Zhanxin Yao Source Type: research

Vitamin B < sub > 6 < /sub > alleviates chronic sleep deprivation-induced hippocampal ferroptosis through CBS/GSH/GPX4 pathway
Biomed Pharmacother. 2024 Apr 9;174:116547. doi: 10.1016/j.biopha.2024.116547. Online ahead of print.ABSTRACTSeveral studies have found that sleep deprivation (SD) can lead to neuronal ferroptosis and affect hippocampal function. However, there are currently no effective interventions. Vitamin B6 is a co-factor for key enzymes in the transsulfuration pathway which is critical for maintaining cell growth in the presence of cysteine deprivation. The results showed that SD inhibited cystine-glutamate antiporter light chain subunit xCT protein expression and caused cysteine deficiency, which reduced the synthesis of the glutat...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 10, 2024 Category: Drugs & Pharmacology Authors: Man Yuan Feng Wang Tieqiang Sun Xiangyu Bian Yuxian Zhang Changjiang Guo Lixia Yu Zhanxin Yao Source Type: research

Association of Serum Folate and Vitamin B < sub > 12 < /sub > Concentrations with Obesity in Chinese Children and Adolescents
CONCLUSION: Higher serum vitamin B 12 concentrations, but not serum folate concentrations, were associated with lower odds of childhood obesity. Children and adolescents with high levels of vitamin B 12 and folate were less likely to be obese.PMID:38582989 | DOI:10.3967/bes2024.028 (Source: Biomedical and Environmental Sciences : BES)
Source: Biomedical and Environmental Sciences : BES - April 7, 2024 Category: Biomedical Science Authors: Qian Rang Zhu E Kok Dieuwertje Hailu Tesfaye Bekele Koen Manusama Jing Xian Zhang Wei Xie Wen Qi Zong Hui Zuo Jian Zhang Ellen Kampman Yue Dai Source Type: research

Association of Serum Folate and Vitamin B < sub > 12 < /sub > Concentrations with Obesity in Chinese Children and Adolescents
CONCLUSION: Higher serum vitamin B 12 concentrations, but not serum folate concentrations, were associated with lower odds of childhood obesity. Children and adolescents with high levels of vitamin B 12 and folate were less likely to be obese.PMID:38582989 | DOI:10.3967/bes2024.028 (Source: Biomedical and Environmental Sciences : BES)
Source: Biomedical and Environmental Sciences : BES - April 7, 2024 Category: Biomedical Science Authors: Qian Rang Zhu E Kok Dieuwertje Hailu Tesfaye Bekele Koen Manusama Jing Xian Zhang Wei Xie Wen Qi Zong Hui Zuo Jian Zhang Ellen Kampman Yue Dai Source Type: research

Association of Serum Folate and Vitamin B < sub > 12 < /sub > Concentrations with Obesity in Chinese Children and Adolescents
CONCLUSION: Higher serum vitamin B 12 concentrations, but not serum folate concentrations, were associated with lower odds of childhood obesity. Children and adolescents with high levels of vitamin B 12 and folate were less likely to be obese.PMID:38582989 | DOI:10.3967/bes2024.028 (Source: Biomedical and Environmental Sciences : BES)
Source: Biomedical and Environmental Sciences : BES - April 7, 2024 Category: Biomedical Science Authors: Qian Rang Zhu E Kok Dieuwertje Hailu Tesfaye Bekele Koen Manusama Jing Xian Zhang Wei Xie Wen Qi Zong Hui Zuo Jian Zhang Ellen Kampman Yue Dai Source Type: research

Association of Serum Folate and Vitamin B < sub > 12 < /sub > Concentrations with Obesity in Chinese Children and Adolescents
CONCLUSION: Higher serum vitamin B 12 concentrations, but not serum folate concentrations, were associated with lower odds of childhood obesity. Children and adolescents with high levels of vitamin B 12 and folate were less likely to be obese.PMID:38582989 | DOI:10.3967/bes2024.028 (Source: Biomedical and Environmental Sciences : BES)
Source: Biomedical and Environmental Sciences : BES - April 7, 2024 Category: Biomedical Science Authors: Qian Rang Zhu E Kok Dieuwertje Hailu Tesfaye Bekele Koen Manusama Jing Xian Zhang Wei Xie Wen Qi Zong Hui Zuo Jian Zhang Ellen Kampman Yue Dai Source Type: research

Association of Serum Folate and Vitamin B < sub > 12 < /sub > Concentrations with Obesity in Chinese Children and Adolescents
CONCLUSION: Higher serum vitamin B 12 concentrations, but not serum folate concentrations, were associated with lower odds of childhood obesity. Children and adolescents with high levels of vitamin B 12 and folate were less likely to be obese.PMID:38582989 | DOI:10.3967/bes2024.028 (Source: Biomedical and Environmental Sciences : BES)
Source: Biomedical and Environmental Sciences : BES - April 7, 2024 Category: Biomedical Science Authors: Qian Rang Zhu E Kok Dieuwertje Hailu Tesfaye Bekele Koen Manusama Jing Xian Zhang Wei Xie Wen Qi Zong Hui Zuo Jian Zhang Ellen Kampman Yue Dai Source Type: research

Association of Serum Folate and Vitamin B < sub > 12 < /sub > Concentrations with Obesity in Chinese Children and Adolescents
CONCLUSION: Higher serum vitamin B 12 concentrations, but not serum folate concentrations, were associated with lower odds of childhood obesity. Children and adolescents with high levels of vitamin B 12 and folate were less likely to be obese.PMID:38582989 | DOI:10.3967/bes2024.028 (Source: Biomedical and Environmental Sciences : BES)
Source: Biomedical and Environmental Sciences : BES - April 7, 2024 Category: Biomedical Science Authors: Qian Rang Zhu E Kok Dieuwertje Hailu Tesfaye Bekele Koen Manusama Jing Xian Zhang Wei Xie Wen Qi Zong Hui Zuo Jian Zhang Ellen Kampman Yue Dai Source Type: research

Association of Serum Folate and Vitamin B < sub > 12 < /sub > Concentrations with Obesity in Chinese Children and Adolescents
CONCLUSION: Higher serum vitamin B 12 concentrations, but not serum folate concentrations, were associated with lower odds of childhood obesity. Children and adolescents with high levels of vitamin B 12 and folate were less likely to be obese.PMID:38582989 | DOI:10.3967/bes2024.028 (Source: Biomedical and Environmental Sciences : BES)
Source: Biomedical and Environmental Sciences : BES - April 7, 2024 Category: Biomedical Science Authors: Qian Rang Zhu E Kok Dieuwertje Hailu Tesfaye Bekele Koen Manusama Jing Xian Zhang Wei Xie Wen Qi Zong Hui Zuo Jian Zhang Ellen Kampman Yue Dai Source Type: research

Association of Serum Folate and Vitamin B < sub > 12 < /sub > Concentrations with Obesity in Chinese Children and Adolescents
CONCLUSION: Higher serum vitamin B 12 concentrations, but not serum folate concentrations, were associated with lower odds of childhood obesity. Children and adolescents with high levels of vitamin B 12 and folate were less likely to be obese.PMID:38582989 | DOI:10.3967/bes2024.028 (Source: Biomedical and Environmental Sciences : BES)
Source: Biomedical and Environmental Sciences : BES - April 7, 2024 Category: Biomedical Science Authors: Qian Rang Zhu E Kok Dieuwertje Hailu Tesfaye Bekele Koen Manusama Jing Xian Zhang Wei Xie Wen Qi Zong Hui Zuo Jian Zhang Ellen Kampman Yue Dai Source Type: research

Association of Serum Folate and Vitamin B < sub > 12 < /sub > Concentrations with Obesity in Chinese Children and Adolescents
CONCLUSION: Higher serum vitamin B 12 concentrations, but not serum folate concentrations, were associated with lower odds of childhood obesity. Children and adolescents with high levels of vitamin B 12 and folate were less likely to be obese.PMID:38582989 | DOI:10.3967/bes2024.028 (Source: Biomedical and Environmental Sciences : BES)
Source: Biomedical and Environmental Sciences : BES - April 7, 2024 Category: Biomedical Science Authors: Qian Rang Zhu E Kok Dieuwertje Hailu Tesfaye Bekele Koen Manusama Jing Xian Zhang Wei Xie Wen Qi Zong Hui Zuo Jian Zhang Ellen Kampman Yue Dai Source Type: research

Folate and vitamin B < sub > 12 < /sub > status and predicted neural tube defects risk among nonpregnant women of reproductive age from the Malawi National Micronutrient Survey, 2015-2016
CONCLUSIONS: These findings highlight the importance of nutritional and NTD surveillance in Malawi and the opportunity for improving folate and vitamin B12 nutrition among Malawian WRA.PMID:38526193 | DOI:10.1002/bdr2.2329 (Source: Cell Research)
Source: Cell Research - March 25, 2024 Category: Cytology Authors: Yan Ping Qi Krista S Crider Anne M Williams Katie Tripp Carine Mapango Elizabeth C Rhodes Eunice Nyirenda Felix Phiri Mindy Zhang Shameem Jabbar Christine M Pfeiffer Helena Pach ón Sarah Zimmerman Jennifer L Williams Source Type: research