Combination of Curcumin and Metformin Inhibits Cell Growth and Induces Apoptosis without Affecting the Cell Cycle in LNCaP Prostate Cancer Cell Line.
Abstract Side effects and chemotherapy resistance, demand new therapeutics with minimal side effects. Here, we investigated the combined effect of curcumin and metformin on the LNCaP prostate cancer cell line. LNCaP cells were treated with curcumin, metformin, and their combination at different concentrations. Cell viability was assessed by MTT assay and expression of Bax, Bcl-2, mTOR, hTERT, PUMA, p53 and p21 genes was analyzed by real-time PCR. Apoptosis and cell cycle were assessed by flow cytometry. Our results revealed that the viability of cells treated with curcumin, metformin, and their combination was sig...
Source: Nutrition and Cancer - July 13, 2020 Category: Cancer & Oncology Authors: Eslami SS, Jafari D, Montazeri H, Sadeghizadeh M, Tarighi P Tags: Nutr Cancer Source Type: research

The Role of the Curcumin for Inducing Apoptosis in Acute Lymphoblastic Leukemia Cells: A Systematic Review.
In this study, we discuss the potential apoptosis and anticancer effect of curcumin on the ALL. After choosing Medical Subject Headings (MeSH) keywords, including "Curcumin", "acute lymphoblastic leukemia", "apoptosis", as well as searching Medline/PubMed, Scopus, Sciencedirect. hand searching in key journals, list of references of selected articles and gray literature, without time and language limitation, articles up to December 2017 were entered into this review. In this review, 244 articles were acquired at the primary search. Study selection and quality assessment processes were done base...
Source: Nutrition and Cancer - July 13, 2020 Category: Cancer & Oncology Authors: Haghighian HK, Ketabchi N, Kavianpour M Tags: Nutr Cancer Source Type: research

The Role of the Curcumin for Inducing Apoptosis in Acute Lymphoblastic Leukemia Cells: A Systematic Review
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - July 13, 2020 Category: Cancer & Oncology Authors: Hossein Khadem Haghighian Neda Ketabchi Maria Kavianpour Source Type: research

Combination of Curcumin and Metformin Inhibits Cell Growth and Induces Apoptosis without Affecting the Cell Cycle in LNCaP Prostate Cancer Cell Line
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - July 13, 2020 Category: Cancer & Oncology Authors: Seyed Sadegh Eslami Davod Jafari Hamed Montazeri Majid Sadeghizadeh Parastoo Tarighi Source Type: research

Regulatory T Cells in Bioactive Peptides-Induced Oral Tolerance; a Two-Edged Sword Related to the Risk of Chronic Diseases: A Systematic Review.
Abstract This systematic review assesses the literature regarding beneficial and potential detrimental effects of bioactive peptides (BPs), focusing on evidence of regulatory T cells (T-regs) mediated oral tolerance (OT), collagen hydrolysate (CH) supplementation in osteoarthritis (OA) and the association of T-regs with chronic disease. The systematic search was done for articles published from inception to April 2019 using the PubMed and Scopus databases. About 3081 papers were identified by three different search strategies and screened against inclusion criteria which resulted in the inclusion of 22 articles. F...
Source: Nutrition and Cancer - July 10, 2020 Category: Cancer & Oncology Authors: Barati M, Jabbari M, Nickho H, Esparvarinha M, Javadi Mamaghani A, Majdi H, Fathollahi A, Davoodi SH Tags: Nutr Cancer Source Type: research

Regulatory T Cells in Bioactive Peptides-Induced Oral Tolerance; a Two-Edged Sword Related to the Risk of Chronic Diseases: A Systematic Review
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - July 10, 2020 Category: Cancer & Oncology Authors: Meisam Barati Masoumeh Jabbari Hamid Nickho Mojgan Esparvarinha Amirreza Javadi Mamaghani Hasan Majdi Anwar Fathollahi Sayed Hossein Davoodi Source Type: research

Anticancer Effects of Extracts from Three Different Chokeberry Species.
In this study, we compared the growth inhibitory activity of three chokeberry extracts in HT-29 human colon cancer cells. The three extracts tested were derived from Aronia arbutifolia (red), Aronia prunifolia (purple), and Aronia melanocarpa (black). Cells were incubated with either red, purple, or black chokeberry extracts and cell viability was quantified using the thiazolyl blue tetrazolium bromide (MTT) assay. The black chokeberry extract had the greatest effect in reducing cell proliferation. The extracts were also characterized for total phenols (Folin-Ciocalteu assay), total antioxidant activity (oxygen radical abs...
Source: Nutrition and Cancer - July 9, 2020 Category: Cancer & Oncology Authors: Gill NK, Rios D, Osorio-Camacena E, Mojica BE, Kaur B, Soderstrom MA, Gonzalez M, Plaat B, Poblete C, Kaur N, Singh H, Forester SC Tags: Nutr Cancer Source Type: research

Anticancer Effects of Extracts from Three Different Chokeberry Species
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - July 9, 2020 Category: Cancer & Oncology Authors: Navpreet K. Gill Diana Rios Elena Osorio-Camacena Benigno E. Mojica Baljinder Kaur Matthew A. Soderstrom Maricarmen Gonzalez Brandy Plaat Clarice Poblete Navdeep Kaur Henna Singh Sarah C. Forester Source Type: research

Botryosphaeran Attenuates Tumor Development and the Cancer Cachexia Syndrome in Walker-256 Tumor-Bearing Obese Rats and Improves the Metabolic and Hematological Profiles of These Rats.
This study evaluated the effects of botryosphaeran on tumor development and metabolic and hematological parameters in tumor-bearing obese and non-obese rats. Obesity was induced by a high-fat and high-sugar diet, while control rats received standard diet and water without sugar for 10 weeks. On 8th-week, Walker-256 tumor cells were inoculated in the rats, and treatment with botryosphaeran (12 mg/Kg b.w.) started. Groups:control tumor-CT, control tumor botryosphaeran-CTB, obese tumor-OT and obese tumor botryosphaeran-OTB. On 10th-week, tumor development, cachexia, metabolic and hematological parameters were an...
Source: Nutrition and Cancer - July 8, 2020 Category: Cancer & Oncology Authors: Comiran PK, Ribeiro MC, Silva JHG, Martins KO, Santos IA, Chiaradia AEF, Silva AZ, Dekker RFH, Barbosa-Dekker AM, Alegranci P, Queiroz EAIF Tags: Nutr Cancer Source Type: research

Botryosphaeran Attenuates Tumor Development and the Cancer Cachexia Syndrome in Walker-256 Tumor-Bearing Obese Rats and Improves the Metabolic and Hematological Profiles of These Rats
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - July 8, 2020 Category: Cancer & Oncology Authors: Patr ícia K. Comiran Mariana C. Ribeiro John H. G. Silva Kamila O. Martins Izabella A. Santos Ana Emilia F. Chiaradia Amadeu Z. Silva Robert F. H. Dekker Aneli M. Barbosa-Dekker P âmela Alegranci Eveline A. I. F. Queiroz Source Type: research

Obesity at Diagnosis and Prostate Cancer Prognosis: A Challenge to Turn the Fate for the Better?
PMID: 32614263 [PubMed - as supplied by publisher] (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - July 2, 2020 Category: Cancer & Oncology Authors: Mormile R Tags: Nutr Cancer Source Type: research

Obesity at Diagnosis and Prostate Cancer Prognosis: A Challenge to Turn the Fate for the Better?
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - July 2, 2020 Category: Cancer & Oncology Authors: Raffaella Mormile Source Type: research

Aloe vera and Honey Solution and Their Ethanolic Extraction Solution Could Act on Metastasis-Regulating Processes in Walker 256 Tumor Tissues In  Vivo?
Aloe vera and Honey Solution and Their Ethanolic Extraction Solution Could Act on Metastasis-Regulating Processes in Walker 256 Tumor Tissues In Vivo? Nutr Cancer. 2020 Jul 01;:1-9 Authors: Tomasin R, Pascoal ACRF, Salvador MJ, Gomes-Marcondes MCC Abstract Research has shown that both Aloe vera and honey have anticancer and nutrition properties, including the inhibition of metastasis. In order to evaluate the effect of a solution of Aloe vera and honey (A) and their ethanolic fraction (F) on metastasis-regulating processes in primary tumors, Wistar rats were subcutaneously implanted with Walker 2...
Source: Nutrition and Cancer - July 1, 2020 Category: Cancer & Oncology Authors: Tomasin R, Pascoal ACRF, Salvador MJ, Gomes-Marcondes MCC Tags: Nutr Cancer Source Type: research

Aloe vera and Honey Solution and Their Ethanolic Extraction Solution Could Act on Metastasis-Regulating Processes in Walker 256 Tumor Tissues In  Vivo?
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - July 1, 2020 Category: Cancer & Oncology Authors: Rebeka Tomasin Aislan Cristina Rheder Fagundes Pascoal Marcos Jos é Salvador Maria Cristina Cintra Gomes-Marcondes Source Type: research

Serum 25-Hydroxyvitamin D Level Is Not Associated with Duration and Activity of Disease in Melanoma Patients.
In conclusion, there was no difference between serum vitamin D levels of melanoma patients and healthy controls and it was also not associated with duration and activity of disease. PMID: 32597224 [PubMed - as supplied by publisher] (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 29, 2020 Category: Cancer & Oncology Authors: Tas F, Erturk K, Oguz Soydinc H Tags: Nutr Cancer Source Type: research

Vitamin D in Acute and Critically Sick Children with a Subgroup of Sepsis and Mortality: A Meta-Analysis.
Abstract A meta-analysis study was performed to evaluate the relationship between vitamin D deficiency children and sepsis and acute and critically mortality. Through a systematic literature search up to December 2019, 23 studies with 4451 children, 2500 children with vitamin D deficiency were identified reporting relationships between vitamin D deficiency and sepsis and/or acute and critical care unit mortality (six sepsis only, four acute and critically mortality only and 13 both sepsis and acute and critically mortality). Odd ratio (OR) with 95% confidence intervals (CIs) was calculated comparing vitamin D defi...
Source: Nutrition and Cancer - June 29, 2020 Category: Cancer & Oncology Authors: Su G, Jia D Tags: Nutr Cancer Source Type: research

Serum 25-Hydroxyvitamin D Level Is Not Associated with Duration and Activity of Disease in Melanoma Patients
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 29, 2020 Category: Cancer & Oncology Authors: Faruk Tas Kayhan Erturk Hilal Oguz Soydinc Source Type: research

Vitamin D in Acute and Critically Sick Children with a Subgroup of Sepsis and Mortality: A Meta-Analysis
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 29, 2020 Category: Cancer & Oncology Authors: Guiyun Su Daofu Jia Source Type: research

Associations between Dietary Fiber, the Fecal Microbiota and Estrogen Metabolism in Postmenopausal Women with Breast Cancer
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 27, 2020 Category: Cancer & Oncology Authors: Ayse G. Zengul Wendy Demark-Wahnefried Stephen Barnes Casey D. Morrow Brenda Bertrand Taylor F. Berryhill Andrew D. Frug é Source Type: research

Integrated Analysis of lncRNAs and mRNAs Identifies a Potential Driver lncRNA FENDRR in Lung Cancer in Xuanwei, China
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 27, 2020 Category: Cancer & Oncology Authors: Yan Wang Yong Duan Wen-Xing Li Ying Zhao Jie Shen Cheng-Jun Deng Qing Li Ran Chen Xiao Liu Yan-Liang Zhang Source Type: research

Associations between Dietary Fiber, the Fecal Microbiota and Estrogen Metabolism in Postmenopausal Women with Breast Cancer.
The objective of this cross-sectional study among 29 newly-diagnosed (stage 0-II), post-menopausal breast cancer patients is to examine associations between dietary fiber and the gut microbiota that are linked with β-glucuronidase activity, and purportedly increase circulating estrogens. Spearman's and partial correlations controlling for body mass index and age were performed using dietary recall data, Illumina MiSeq generated microbiota relative abundance, and HPLC-mass spectrometry-derived estradiol and estrone levels.Major findings are: (1) total dietary fiber is inversely associated with Clostridium hathewayi (r=...
Source: Nutrition and Cancer - June 26, 2020 Category: Cancer & Oncology Authors: Zengul AG, Demark-Wahnefried W, Barnes S, Morrow CD, Bertrand B, Berryhill TF, Frugé AD Tags: Nutr Cancer Source Type: research

Integrated Analysis of lncRNAs and mRNAs Identifies a Potential Driver lncRNA FENDRR in Lung Cancer in Xuanwei, China.
This study was to screen out potential driver long non-coding RNAs (lncRNAs) in lung cancer in Xuanwei (LCXW) differently expressed mRNAs and lncRNAs were detected by gene expression microarrays in 23 paired lung adenocarcinoma and adjacent tissues. Combined bioinformatics analysis was performed to identify potential driver lncRNAs and their potential regulatory relationships. Transcriptome and clinical data in TCGA-LUAD were used as comparison and validation dataset. The comparison of LCXW and TCGA-LUAD revealed significant differences in expression of some genes, signaling pathways affected by differentially expressed ge...
Source: Nutrition and Cancer - June 26, 2020 Category: Cancer & Oncology Authors: Wang Y, Duan Y, Li WX, Zhao Y, Shen J, Deng CJ, Li Q, Chen R, Liu X, Zhang YL Tags: Nutr Cancer Source Type: research

Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 26, 2020 Category: Cancer & Oncology Authors: Hongliang Sun Taotao Zhang Rui Liu Wanshuang Cao Zhiqiang Zhang Zhiqi Liu Weiwei Qian Dengdian Wang Dexin Yu Caiyun Zhong Source Type: research

Home Parenteral Nutrition in Patients with Advanced Cancer: A Systematic Review and Meta-Analysis
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 26, 2020 Category: Cancer & Oncology Authors: Francis J. O ’Hanlon Konstantinos C. Fragkos Lucia Fini Pinal S. Patel Shameer J. Mehta Farooq Rahman Simona Di Caro Source Type: research

Synergistic Evaluation of Ginger and Licorice Extracts in a Mouse Model of Colorectal Cancer
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 26, 2020 Category: Cancer & Oncology Authors: Amir Mohammad Saeedifar Ghasem Mosayebi Ali Ghazavi Ali Ganji Source Type: research

The Arachis hypogaea Essential Oil Nanoemulsion as an Efficient Safe Apoptosis Inducer in Human Lung Cancer Cells (A549)
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 26, 2020 Category: Cancer & Oncology Authors: Parastoo Fazelifar Masoud Homayouni Tabrizi Aras Rafiee Source Type: research

Identification of Key mRNAs and Pathways in Colorectal Cancer
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 26, 2020 Category: Cancer & Oncology Authors: Xiaolin Hou Nengyi Hou Junwen Fu Xuelai He Haibo Xiong Wei Xie Guiqing Jia Xiaofei Zuo Xianpeng Qin Minghui Pang Source Type: research

Home Parenteral Nutrition in Patients with Advanced Cancer: A Systematic Review and Meta-Analysis.
In conclusion, HPN is used for several indications in advanced cancer, though there is significant heterogeneity of results. Disparities in geographical distribution of the studies may reflect variation in accessing HPN. PMID: 32586120 [PubMed - as supplied by publisher] (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 25, 2020 Category: Cancer & Oncology Authors: O'Hanlon FJ, Fragkos KC, Fini L, Patel PS, Mehta SJ, Rahman F, Di Caro S Tags: Nutr Cancer Source Type: research

Identification of Key mRNAs and Pathways in Colorectal Cancer.
Abstract Colorectal cancer (CRC) is the third most cancer-related death worldwide. This work aimed to identify potential hub genes and dysregulated pathways in the CRC by bioinformatics analysis. Three gene expression datasets were collected from GEO datasets, including tumor sample (N = 242) and adjacent nontumor tissue sample (N = 59). RankProd was used to discover the differential expressed genes between tumor and adjacent nontumor tissues for datasets generated by different laboratories. The gene set enrichment analysis conducted on the DE genes, followed by the protein-protein inte...
Source: Nutrition and Cancer - June 25, 2020 Category: Cancer & Oncology Authors: Hou X, Hou N, Fu J, He X, Xiong H, Xie W, Jia G, Zuo X, Qin X, Pang M Tags: Nutr Cancer Source Type: research

The Arachis hypogaea Essential Oil Nanoemulsion as an Efficient Safe Apoptosis Inducer in Human Lung Cancer Cells (A549).
In conclusion, AHO-NE has the potential to be used as an exclusive cell-dependent anticancer compound in A549 lung cancer cells. PMID: 32586130 [PubMed - as supplied by publisher] (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 25, 2020 Category: Cancer & Oncology Authors: Fazelifar P, Tabrizi MH, Rafiee A Tags: Nutr Cancer Source Type: research

Synergistic Evaluation of Ginger and Licorice Extracts in a Mouse Model of Colorectal Cancer.
This study aimed to evaluate the anticancer activities of ginger and licorice extracts, as well as the synergistic effects of their combination. Ginger ethanolic extract (GEE) and licorice methanolic extract (LME) were isolated by a Soxhlet extractor. Next, the anti-proliferative activity of the extracts, apoptosis induction, tumor growth inhibition, and tumor-infiltrating T lymphocytes were investigated. The MTT (3-[4, 5-dimethylthiazol-2-yl]-2, five diphenyl tetrazolium bromide) assay showed that GEE and LME decreased the CT26 cell viability in a dose-dependent manner; however, the GEE + LME combination was...
Source: Nutrition and Cancer - June 25, 2020 Category: Cancer & Oncology Authors: Saeedifar AM, Mosayebi G, Ghazavi A, Ganji A Tags: Nutr Cancer Source Type: research

Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Conclusions: These results suggested that resveratrol is a potential novel therapeutic agent that targets inactivation of renal CSCs by affecting the function of the Shh pathway. PMID: 32586140 [PubMed - as supplied by publisher] (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 25, 2020 Category: Cancer & Oncology Authors: Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, Qian W, Wang D, Yu D, Zhong C Tags: Nutr Cancer Source Type: research

A Licorice Roots Extract Induces Apoptosis and Cell Cycle Arrest and Improves Metabolism via Regulating MiRNAs in Liver Cancer Cells.
Abstract Targeting altered metabolism in cancer provides a promising preventive and therapeutic approach. Natural products interplay between gene expression and metabolism either by targeting altered metabolic enzymes and/or affecting the regulating miRNAs. Licorice is a widely known product used as flavoring agent. Glycyrrhizin and other metabolites were reported to exert several metabolic benefits. Here, we investigated the effect of licorice roots extract on some metabolic pathways and their regulating miRNAs in hepatocellular carcinoma cells. Our data showed various beneficial effects of licorice roots extract...
Source: Nutrition and Cancer - June 24, 2020 Category: Cancer & Oncology Authors: Abdel-Wahab AA, Effat H, Mahrous EA, Ali MA, Al-Shafie TA Tags: Nutr Cancer Source Type: research

A Licorice Roots Extract Induces Apoptosis and Cell Cycle Arrest and Improves Metabolism via Regulating MiRNAs in Liver Cancer Cells  
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 24, 2020 Category: Cancer & Oncology Authors: Abdel-Hady A. Abdel-Wahab Heba Effat Engy A. Mahrous Mennatallah A. Ali Tamer A. Al-Shafie Source Type: research

Edible Sword Bean Extract Induces Apoptosis in Cancer Cells In  Vitro and Inhibits Ascites and Solid Tumor Development In Vivo.
Edible Sword Bean Extract Induces Apoptosis in Cancer Cells In Vitro and Inhibits Ascites and Solid Tumor Development In Vivo. Nutr Cancer. 2020 Jun 22;:1-11 Authors: Abeesh P, Rasmi RR, Guruvayoorappan C Abstract Antitumor potential of edible sword bean (Canavalia gladiata (L.)) extract has been evaluated against Daltons lymphoma ascites (DLA) using in vitro and in vivo studies. Methanolic extraction was carried out and in vitro studies were performed against both DLA and A549, lung cancer cell lines. The results revealed that sword bean extract inhibited cell growth and indu...
Source: Nutrition and Cancer - June 22, 2020 Category: Cancer & Oncology Authors: Abeesh P, Rasmi RR, Guruvayoorappan C Tags: Nutr Cancer Source Type: research

Edible Sword Bean Extract Induces Apoptosis in Cancer Cells In  Vitro and Inhibits Ascites and Solid Tumor Development In Vivo
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 22, 2020 Category: Cancer & Oncology Authors: Prathapan Abeesh Rajan Radha Rasmi Chandrasekharan Guruvayoorappan Source Type: research

Safety of Eicosapentaenoic Acid in Cancer Treatment: Effect on Cancer Cells and Chemotherapy in  Vitro
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 17, 2020 Category: Cancer & Oncology Authors: Safiye Akta ş P ınar Ercetin Zekiye Altun Mehmet Kantar Nur Olgun Source Type: research

Effects of CLIC4 on Fucoxanthinol-Induced Apoptosis in Human Colorectal Cancer Cells
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 17, 2020 Category: Cancer & Oncology Authors: Reo Yokoyama Hiroyuki Kojima Rie Takai Tohru Ohta Hayato Maeda Kazuo Miyashita Michihiro Mutoh Masaru Terasaki Source Type: research

Isocaloric Ketogenic Diet in Adults with High-Grade Gliomas: A Prospective Metabolic Study
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 17, 2020 Category: Cancer & Oncology Authors: Andrea Foppiani Ramona De Amicis Chiara Lessa Alessandro Leone Simone Ravella Emilio Ciusani Antonio Silvani Giulio Zuccoli Alberto Battezzati Elena Lamperti Simona Bertoli Source Type: research

Mechanisms of Anti-Tumor Activity of Withania somnifera (Ashwagandha)
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 17, 2020 Category: Cancer & Oncology Authors: Vikrant Mehta Harish Chander Anjana Munshi Source Type: research

High Serum Uric Acid Levels Could Be a Risk Factor of Hepatocellular Carcinoma Recurrences.
Conclusions: High SUA implies a significant risk factor of activating hepatocarcinogenesis. Keeping the SUA level low may be recommended after HCC resections. PMID: 32538144 [PubMed - as supplied by publisher] (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 15, 2020 Category: Cancer & Oncology Authors: Hayashi M, Yamada S, Tanabe H, Takami H, Inokawa Y, Sonohara F, Shimizu D, Hattori N, Kanda M, Tanaka C, Nakayama G, Koike M, Fujiwara M, Kodera Y Tags: Nutr Cancer Source Type: research

High Serum Uric Acid Levels Could Be a Risk Factor of Hepatocellular Carcinoma Recurrences
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 15, 2020 Category: Cancer & Oncology Authors: Masamichi Hayashi Suguru Yamada Hiroshi Tanabe Hideki Takami Yoshikuni Inokawa Fuminori Sonohara Dai Shimizu Norifumi Hattori Mitsuro Kanda Chie Tanaka Goro Nakayama Masahiko Koike Michitaka Fujiwara Yasuhiro Kodera Source Type: research

Dietary Intake of N-3 and N-6 Polyunsaturated Fatty Acids and Risk of Cancer: Meta-Analysis of Data from 32 Studies
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 12, 2020 Category: Cancer & Oncology Authors: Jian Liu Xianqing Li Jinfei Hou Jiaming Sun Nengqiang Guo Zhenxing Wang Source Type: research

Overview of Morin and Its Complementary Role as an Adjuvant for Anticancer Agents
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 12, 2020 Category: Cancer & Oncology Authors: Solaipriya Solairaja Mohammad Qasim Andrabi Nageswara Rao Dunna Sivaramakrishnan Venkatabalasubramanian Source Type: research

Curcumin Enriched VCO Protects against 7,12-Dimethyl Benz[a] Anthracene-Induced Skin Papilloma in Mice
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 12, 2020 Category: Cancer & Oncology Authors: Arunaksharan Narayanankutty Anusree Nair Soorya Parathodi Illam Aman Upaganlawar Achuthan C. Raghavamenon Source Type: research

Phenolic Extraction of Moringa Oleifera Leaves Induces Caspase-Dependent and Caspase-Independent Apoptosis through the Generation of Reactive Oxygen Species and the Activation of Intrinsic Mitochondrial Pathway in Human Melanoma Cells
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 12, 2020 Category: Cancer & Oncology Authors: Bich Hang Do Nghia Son Hoang Thi Phuong Thao Nguyen Nguyen Quynh Chi Ho Thanh Long Le Chinh Chung Doan Source Type: research

Overview of Morin and Its Complementary Role as an Adjuvant for Anticancer Agents.
Abstract The Global cancer incidence and mortality data released by the World Health Organization proposes that out of 18.1 million new cancer cases diagnosed, 9.8 million deaths occurred globally in 2018. Cancer is one of the major health burdens among non-communicable diseases globally responsible for impeding life expectancy in the present century. Disrupting hallmarks of cancer (such as prolonged inflammation, increased growth signal, tissue invasion and metastasis, unlimited proliferation and evasion of apoptosis) with dietary agents is of considerable focus for cancer prevention and therapy. In the last deca...
Source: Nutrition and Cancer - June 12, 2020 Category: Cancer & Oncology Authors: Solairaja S, Andrabi MQ, Dunna NR, Venkatabalasubramanian S Tags: Nutr Cancer Source Type: research

Curcumin Enriched VCO Protects against 7,12-Dimethyl Benz[a] Anthracene-Induced Skin Papilloma in Mice.
In this study, the chemopreventive potential of curcumin enriched VCO (VCr) (4 and 8 mL/Kg orally) was analyzed in 7,12-dimethyl benz[a]anthracene (DMBA;470 nmoles/200 µL/week for two weeks topical)/croton oil (3% v/v in 200 µL acetone twice a week for 6 weeks topical) induced skin papilloma. In DMBA control animals, an average incidence of 13 papilloma/mice (latency period of 11.6 ± 1.5 weeks) was recorded. Pretreatment with VCrH (8 mL/kg) had a 60% inhibition of tumor index, and an increased latency period (12.5 ± 0.9 w...
Source: Nutrition and Cancer - June 12, 2020 Category: Cancer & Oncology Authors: Narayanankutty A, Nair A, Illam SP, Upaganlawar A, Raghavamenon AC Tags: Nutr Cancer Source Type: research

Phenolic Extraction of Moringa Oleifera Leaves Induces Caspase-Dependent and Caspase-Independent Apoptosis through the Generation of Reactive Oxygen Species and the Activation of Intrinsic Mitochondrial Pathway in Human Melanoma Cells.
Abstract Moringa oleifera Lam. has long been used to treat many diseases, including diabetes, aging, inflammatory, and cancer. Many studies have revealed that the crude extract of Moringa oleifera Lam. leaves possesses anticancer property. Therefore, in this study, the extract of Moringa oleifera leaves was fractionated using different solvents to figure out the most effective fraction for anti-proliferative effect on melanoma cells. Methanol extract (MO-ME), hexane fraction (MO-HE), chloroform fraction (MO-CH), ethyl acetate fraction (MO-EA), and water-soluble fraction (MO-WA) of Moringa oleifera leaves were prep...
Source: Nutrition and Cancer - June 12, 2020 Category: Cancer & Oncology Authors: Do BH, Hoang NS, Nguyen TPT, Ho NQC, Le TL, Doan CC Tags: Nutr Cancer Source Type: research

Dietary Intake of N-3 and N-6 Polyunsaturated Fatty Acids and Risk of Cancer: Meta-Analysis of Data from 32 Studies.
Conclusions: Most subtypes of PUFAs are probably not related to cancers. However, additional high-quality trials are warranted to corroborate the findings of this meta-analysis. PMID: 32530319 [PubMed - as supplied by publisher] (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - June 12, 2020 Category: Cancer & Oncology Authors: Liu J, Li X, Hou J, Sun J, Guo N, Wang Z Tags: Nutr Cancer Source Type: research