Complete investigations (autopsy, toxicology, and histology) in a death due to apixaban overdose
AbstractThe dead body of a 54-year-old man was found at home by his partner. He was off work due to depression. A letter with suicidal intention was present on the scene. He was known to be a heavy drinker, and near the body, an empty bottle of whisky was found. In addition, 2 empty blisters of Eliquis (apixaban) 5 mg, corresponding to 40 tablets, were identified. Apixaban is an oral anticoagulant, acting as a factor Xa inhibitor. Autopsy findings were mostly unremarkable, except numerous bruises and some superficial self-inflected wounds. Histology showed hematomas of calyces and renal pelvis and in the liver, several are...
Source: International Journal of Legal Medicine - October 24, 2023 Category: Medical Law Source Type: research
Circulating acyl-CoA-binding protein/diazepam-binding inhibitor in gestational diabetes mellitus
CONCLUSIONS: Circulating ACBP is not a marker of GDM status, but ACBP is decreased during pregnancy, irrespective of GDM status. Furthermore, ACBP is related to beta cell function and renal markers in women after pregnancy.PMID:37872629 | DOI:10.1186/s12958-023-01152-z (Source: Reproductive Biology)
Source: Reproductive Biology - October 23, 2023 Category: Reproduction Medicine Authors: Robin Sch ürfeld Ekaterine Baratashvili Marleen W ürfel Matthias Bl üher Michael Stumvoll Anke T önjes Thomas Ebert Source Type: research
Circulating acyl-CoA-binding protein/diazepam-binding inhibitor in gestational diabetes mellitus
CONCLUSIONS: Circulating ACBP is not a marker of GDM status, but ACBP is decreased during pregnancy, irrespective of GDM status. Furthermore, ACBP is related to beta cell function and renal markers in women after pregnancy.PMID:37872629 | DOI:10.1186/s12958-023-01152-z (Source: Reproductive Biology)
Source: Reproductive Biology - October 23, 2023 Category: Reproduction Medicine Authors: Robin Sch ürfeld Ekaterine Baratashvili Marleen W ürfel Matthias Bl üher Michael Stumvoll Anke T önjes Thomas Ebert Source Type: research
Circulating acyl-CoA-binding protein/diazepam-binding inhibitor in gestational diabetes mellitus
Acyl-CoA-binding protein (ACBP)/diazepam-binding inhibitor has recently been characterized as an endocrine factor affecting energy balance and lipid metabolism. However, regulation of ACBP in women with gestat... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - October 23, 2023 Category: Endocrinology Authors: Robin Sch ürfeld, Ekaterine Baratashvili, Marleen Würfel, Matthias Blüher, Michael Stumvoll, Anke Tönjes and Thomas Ebert Tags: Research Source Type: research
Valerenic acid reduces anxiety-like behavior in young adult, female (C57BL/6J) mice
Behav Brain Res. 2023 Oct 16:114717. doi: 10.1016/j.bbr.2023.114717. Online ahead of print.ABSTRACTExtracts from the plant Valeriana officinalis are marketed as an herbal remedy to treat anxiety and insomnia. Valerenic acid (VA) is a major chemical component of Valeriana extracts. To date, there is relatively little information about how VA affects behavior. The purpose of these experiments was to (1) test whether administration of VA induces measurable changes in anxiety-like, depression-like, or locomotor behaviors; (2) determine whether the effects of VA on behavior are dose-dependent; and (3) compare the effects of VA ...
Source: Brain Research - October 18, 2023 Category: Neurology Authors: Natalie E Pinder Isaac Y Ligocki Brent M Horton John E Hoover Source Type: research
Valerenic acid reduces anxiety-like behavior in young adult, female (C57BL/6J) mice
Behav Brain Res. 2023 Oct 16:114717. doi: 10.1016/j.bbr.2023.114717. Online ahead of print.ABSTRACTExtracts from the plant Valeriana officinalis are marketed as an herbal remedy to treat anxiety and insomnia. Valerenic acid (VA) is a major chemical component of Valeriana extracts. To date, there is relatively little information about how VA affects behavior. The purpose of these experiments was to (1) test whether administration of VA induces measurable changes in anxiety-like, depression-like, or locomotor behaviors; (2) determine whether the effects of VA on behavior are dose-dependent; and (3) compare the effects of VA ...
Source: Behavioural Brain Research - October 18, 2023 Category: Neurology Authors: Natalie E Pinder Isaac Y Ligocki Brent M Horton John E Hoover Source Type: research
The real-world effectiveness of intravenous brivaracetam as a second-line treatment in status epilepticus
CONCLUSION: The present study highlights the potential of BRV when used as an early add-on therapy in SE, further confirming its good safety profile.PMID:37839249 | DOI:10.1016/j.yebeh.2023.109464 (Source: Epilepsy and Behaviour)
Source: Epilepsy and Behaviour - October 15, 2023 Category: Neurology Authors: Chiara Martellino Angelina Lagan à Giorgia Atanasio Fabio Lamanna Silvia Attardo Simona Cascino Marcella De Luca Orazio Pardeo Giuseppa Giacobbe Giovanni Tripepi Roberta Roberti Francesca Granata Carmela Morace Emilio Russo Angelo Labate Source Type: research
The real-world effectiveness of intravenous brivaracetam as a second-line treatment in status epilepticus
CONCLUSION: The present study highlights the potential of BRV when used as an early add-on therapy in SE, further confirming its good safety profile.PMID:37839249 | DOI:10.1016/j.yebeh.2023.109464 (Source: Epilepsy and Behaviour)
Source: Epilepsy and Behaviour - October 15, 2023 Category: Neurology Authors: Chiara Martellino Angelina Lagan à Giorgia Atanasio Fabio Lamanna Silvia Attardo Simona Cascino Marcella De Luca Orazio Pardeo Giuseppa Giacobbe Giovanni Tripepi Roberta Roberti Francesca Granata Carmela Morace Emilio Russo Angelo Labate Source Type: research
Therapeutic Efficacy of Head Gusha Combined with Kaitianmen in the Management of Insomnia
CONCLUSIONS: The combination of specialized head scraping and Kaitianmen therapy has demonstrated effectiveness in the treatment of insomnia and offers a valid means of alleviating patients' negative emotions. These findings suggest promising prospects for clinical applications.PMID:37820682 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - October 11, 2023 Category: Complementary Medicine Authors: Lanting Yan Liying Jiang Yue Liu Yun Chen Jiayan Zhong Dingtian Luo Source Type: research
Therapeutic Efficacy of Head Gusha Combined with Kaitianmen in the Management of Insomnia
CONCLUSIONS: The combination of specialized head scraping and Kaitianmen therapy has demonstrated effectiveness in the treatment of insomnia and offers a valid means of alleviating patients' negative emotions. These findings suggest promising prospects for clinical applications.PMID:37820682 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - October 11, 2023 Category: Complementary Medicine Authors: Lanting Yan Liying Jiang Yue Liu Yun Chen Jiayan Zhong Dingtian Luo Source Type: research
