Prices, availability and affordability of selected essential medicines for chronic diseases in T ürkiye
CONCLUSION: This research highlights priority areas of action to improve access to affordable medicines for chronic diseases in Ankara, Türkiye.PMID:38279880 | DOI:10.26719/emhj.23.117 (Source: Eastern Mediterranean Health Journal)
Source: Eastern Mediterranean Health Journal - January 27, 2024 Category: Middle East Health Authors: G ökçen Özler O ğuz Işik Source Type: research
A real-world pharmacovigilance study of FDA adverse event reporting system events for diazepam
Conclusion: Our study identified potential signals of new AEs that could provide strong support for clinical monitoring and risk identification of diazepam. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 24, 2024 Category: Drugs & Pharmacology Source Type: research
JM-20 potently prevents the onset of caffeine-induced anxiogenic phenotypes in zebrafish (Danio rerio)
Comp Biochem Physiol C Toxicol Pharmacol. 2024 Mar;277:109843. doi: 10.1016/j.cbpc.2024.109843. Epub 2024 Jan 17.ABSTRACTAnxiety is among the most prevalent mental disorders present in the general population. Benzodiazepines are the most commonly prescribed drugs for the treatment of anxiety. Using zebrafish as a model organism, we investigated the anxiolytic activity of JM-20, a novel hybrid molecule with a 1,5-benzodiazepine ring fused to a dihydropyridine moiety. Firstly, we carried out some assays to analyze the possible toxicity mediated by JM-20. For this, zebrafish were exposed to different JM-20 concentrations (0-5...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - January 18, 2024 Category: Biochemistry Authors: Matheus M ülling Dos Santos Sabrina Antunes Ferreira Gabriel Teixeira de Macedo Mariana Torri Claro Talise Ellwanger M üller Alessandro de Souza Prestes Jo ão Batista Teixeira da Rocha Yanier N úñez-Figueredo Nilda de Vargas Barbosa Source Type: research
Systematic Review of Local Anaesthetic Systemic Toxicity in Urology
CONCLUSION: LAST is seen only rarely in adult urology. Most iatrogenic cases occur due to penile dorsal nerve block and most patients have no long-term sequelae. Urologists should be familiar with its presentation and management, and minimise risk by adhering to local anaesthetic maximum safe dose ranges.PMID:38237111 | DOI:10.52198/23.STI.43.UR1725 (Source: Surgical Technology International)
Source: Surgical Technology International - January 18, 2024 Category: Surgery Authors: Claris Oh Stephen Kinnear Derek Hennessey James Adshead Nikhil Vasdev Ned Kinnear Source Type: research
