Viruses, Vol. 14, Pages 423: Characterization of Influenza D Virus in Danish Calves
This study is, to our knowledge, the first to describe the characterization of IDV in calves in Denmark. (Source: Viruses)
Source: Viruses - February 18, 2022 Category: Virology Authors: Nicole B. Goecke Yuan Liang Nina D. Otten Charlotte K. Hjulsager Lars E. Larsen Tags: Article Source Type: research
Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells
Mucosal Immunology, Published online: 10 February 2022; doi:10.1038/s41385-021-00478-4Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells (Source: Mucosal Immunology)
Source: Mucosal Immunology - February 10, 2022 Category: Allergy & Immunology Authors: Veronica Martini Matthew Edmans Simon Gubbins Siddharth Jayaraman Basudev Paudyal Sophie Morgan Adam McNee Th éo Morin Pramila Rijal Wilhelm Gerner Andrew K. Sewell Ryo Inoue Mick Bailey Timothy Connelley Bryan Charleston Alain Townsend Peter Beverley El Source Type: research
Reverse Genetics for Influenza A and B Viruses Driven by Swine Polymerase I Promoter
Methods Mol Biol. 2022;2465:257-281. doi: 10.1007/978-1-0716-2168-4_14.ABSTRACTInfluenza viruses are considered prominent pathogens of humans and animals that are extensively investigated because of public health importance. Plasmid-based reverse genetics is a fundamental tool that facilitates the generation of genetically modified viruses from a cDNA copy. The ability to rescue viruses enables researchers to understand different biological characteristics including IV replication, pathogenesis, and transmission. Furthermore, understanding the biology and ability to manipulate different aspects of the virus can aid in prov...
Source: Mol Biol Cell - February 4, 2022 Category: Molecular Biology Authors: Brittany Seibert Stivalis Cardenas-Garcia Daniela Rajao Daniel R Perez Source Type: research
Prevalence of porcine viral respiratory diseases in India
Anim Biotechnol. 2022 Feb 3:1-13. doi: 10.1080/10495398.2022.2032117. Online ahead of print.ABSTRACTThe pig industry is growing rapidly in India and contributes a major share of growth in the livestock sector. Over the last few years, there is a gradual increase in the adoption of pigs for production by economically weaker sections of the country. However, this production is affected by many respiratory diseases which are responsible for significant economic loss. The occurrence and impact of these diseases are still under-documented. The four important pathogens including porcine circovirus type 2 (PCV2), porcine reproduc...
Source: Animal Biotechnology - February 3, 2022 Category: Biotechnology Authors: Neha Singh Kanisht Batra Deepika Chaudhary Monika Punia Aman Kumar Narender Singh Maan Sushila Maan Source Type: research
Prevalence of porcine viral respiratory diseases in India
Anim Biotechnol. 2022 Feb 3:1-13. doi: 10.1080/10495398.2022.2032117. Online ahead of print.ABSTRACTThe pig industry is growing rapidly in India and contributes a major share of growth in the livestock sector. Over the last few years, there is a gradual increase in the adoption of pigs for production by economically weaker sections of the country. However, this production is affected by many respiratory diseases which are responsible for significant economic loss. The occurrence and impact of these diseases are still under-documented. The four important pathogens including porcine circovirus type 2 (PCV2), porcine reproduc...
Source: Animal Biotechnology - February 3, 2022 Category: Biotechnology Authors: Neha Singh Kanisht Batra Deepika Chaudhary Monika Punia Aman Kumar Narender Singh Maan Sushila Maan Source Type: research
Prevalence of porcine viral respiratory diseases in India
Anim Biotechnol. 2022 Feb 3:1-13. doi: 10.1080/10495398.2022.2032117. Online ahead of print.ABSTRACTThe pig industry is growing rapidly in India and contributes a major share of growth in the livestock sector. Over the last few years, there is a gradual increase in the adoption of pigs for production by economically weaker sections of the country. However, this production is affected by many respiratory diseases which are responsible for significant economic loss. The occurrence and impact of these diseases are still under-documented. The four important pathogens including porcine circovirus type 2 (PCV2), porcine reproduc...
Source: Animal Biotechnology - February 3, 2022 Category: Biotechnology Authors: Neha Singh Kanisht Batra Deepika Chaudhary Monika Punia Aman Kumar Narender Singh Maan Sushila Maan Source Type: research
Prevalence of porcine viral respiratory diseases in India
Anim Biotechnol. 2022 Feb 3:1-13. doi: 10.1080/10495398.2022.2032117. Online ahead of print.ABSTRACTThe pig industry is growing rapidly in India and contributes a major share of growth in the livestock sector. Over the last few years, there is a gradual increase in the adoption of pigs for production by economically weaker sections of the country. However, this production is affected by many respiratory diseases which are responsible for significant economic loss. The occurrence and impact of these diseases are still under-documented. The four important pathogens including porcine circovirus type 2 (PCV2), porcine reproduc...
Source: Animal Biotechnology - February 3, 2022 Category: Biotechnology Authors: Neha Singh Kanisht Batra Deepika Chaudhary Monika Punia Aman Kumar Narender Singh Maan Sushila Maan Source Type: research
GSE182645 Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory cells
Contributors : Veronica Martini ; Siddharth Jayaraman ; Timothy Connelley ; Elma TchilianSeries Type : Expression profiling by high throughput sequencingOrganism : Sus scrofaWe have defined na ïve, central memory, effector memory and terminally differentiated porcine CD8 T cells, using CD45RA and CCR7 mAbs. We analyzed the phenotype of CD8 T cells specific for three influenza nucleoprotein (NP) epitopes using tetramers after influenza infection or immunization in lymphoid and respiratory tissues. The hierarchy of response to the three epitopes changes during the response in different tissues. Most NP-specific CD8 T ...
Source: GEO: Gene Expression Omnibus - February 1, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Sus scrofa Source Type: research
Viruses, Vol. 14, Pages 224: Time-Dependent Proinflammatory Responses Shape Virus Interference during Coinfections of Influenza A Virus and Influenza D Virus
This study facilitates our understanding of virus epidemiology and pathogenesis associated with IAV and IDV coinfection. (Source: Viruses)
Source: Viruses - January 24, 2022 Category: Virology Authors: Minhui Guan Sherry Blackmon Alicia K. Olivier Xiaojian Zhang Liyuan Liu Amelia Woolums Mark A. Crenshaw Shengfa F. Liao Richard Webby William Epperson Xiu-Feng Wan Tags: Article Source Type: research
Sensors, Vol. 22, Pages 708: Photonic Label-Free Biosensors for Fast and Multiplex Detection of Swine Viral Diseases
Athnasios I. Gelasakis
Ioannis Bossis
Gyula Balka
Lilla Dénes
Maciej Frant
Lapo Nannucci
Matteo Bonasso
Alessandro Giusti
Amadeu Griol
In this paper we present the development of photonic integrated circuit (PIC) biosensors for the label-free detection of six emerging and endemic swine viruses, namely: African Swine Fever Virus (ASFV), Classical Swine Fever Virus (CSFV), Porcine Reproductive and Respiratory Syndrome Virus (PPRSV), Porcine Parvovirus (PPV), Porcine Circovirus 2 (PCV2), and Swine Influenza Virus A (SIV). The optical biosensors are based on evanescent wave technology and, in particular...
Source: Sensors - January 18, 2022 Category: Biotechnology Authors: Maribel G ómez-Gómez Carles S ánchez Sergio Peransi David Zurita Laurent Bellieres Sara Recuero Manuel Rodrigo Santiago Sim ón Alessandra Camarca Alessandro Capo Maria Staiano Antonio Varriale Sabato D ’Auria Georgios Manessis Athnasios I. Gelasakis Tags: Article Source Type: research
Dendrimer nanoplatforms for veterinary medicine applications: A concise overview
Drug Discov Today. 2022 Jan 6:S1359-6446(22)00001-0. doi: 10.1016/j.drudis.2022.01.001. Online ahead of print.ABSTRACTWithin the nanoparticle (NP) space, dendrimers are becoming increasingly important in the field of nanomedicine, not only to treat human diseases, but also in veterinary medicine, which represents a new therapeutic approach. Major applications include using dendrimers to tackle highly contagious foot-and-mouth disease virus (FMDV) and swine fever virus (SFV) in pigs, FMDV in cattle, hypothermic circulatory arrest (HCA) in dogs, rabies, and H9N2 avian influenza virus in chickens. As we review here, intramusc...
Source: Drug Discovery Today - January 9, 2022 Category: Drugs & Pharmacology Authors: Serge Mignani Xiangyang Shi Jo ão Rodrigues Helena Tom ás Jean-Pierre Majoral Source Type: research
Inherent heterogeneity of influenza A virus stability following aerosolization
Appl Environ Microbiol. 2022 Jan 5:aem0227121. doi: 10.1128/aem.02271-21. Online ahead of print.ABSTRACTEfficient human-to-human transmission represents a necessary adaptation for a zoonotic influenza A virus (IAV) to cause a pandemic. As such, many emerging IAVs are characterized for transmissibility phenotypes in mammalian models, with an emphasis on elucidating viral determinants of transmission and the role host immune responses contribute to mammalian adaptation. Investigations of virus infectivity and stability in aerosols concurrent with transmission assessments have increased in recent years, enhancing our understa...
Source: Applied and Environmental Microbiology - January 5, 2022 Category: Microbiology Authors: Jessica A Belser Joanna A Pulit-Penaloza Nicole Brock Hannah M Creager Kortney M Gustin Terrence M Tumpey Taronna R Maines Source Type: research
[PERSPECTIVES] Equine Influenza
Horses are the third major mammalian species, along with humans and swine, long known to be subject to acute upper respiratory disease from influenza A virus infection. The viruses responsible are subtype H7N7, which is believed extinct, and H3N8, which circulates worldwide. The equine influenza lineages are clearly divergent from avian influenza lineages of the same subtypes. Their genetic evolution and potential for interspecies transmission, as well as clinical features and epidemiology, are discussed. Equine influenza is spread internationally and vaccination is central to control efforts. The current mechanism of inte...
Source: Cold Spring Harbor perspectives in medicine - January 4, 2022 Category: Research Authors: Chambers, T. M. Tags: Influenza: The Cutting Edge PERSPECTIVES Source Type: research
The A179L Gene of African Swine Fever Virus Suppresses Virus-Induced Apoptosis but Enhances Necroptosis
Viruses. 2021 Dec 13;13(12):2490. doi: 10.3390/v13122490.ABSTRACTA179L, a non-structural protein of African swine fever virus (ASFV), is capable of suppressing apoptosis by binding the BH3 domain of the pro-apoptotic Bcl-2 family proteins via a conserved ligand binding groove. Our present study aims to determine if A179L affects necroptosis, the second form of programmed cell death induced by DNA and RNA viruses. Here we report that A179L enhanced TNF-α or TSZ (TNF-α, Smac, and Z-Vad)-induced receptor-interacting protein kinase (RIPK1), RIPK3, and mixed lineage kinase domain like peudokinase (MLKL) phosphorylation in L92...
Source: Herpes - December 28, 2021 Category: Infectious Diseases Authors: Jun Shi Wei Liu Miao Zhang Jing Sun Xiulong Xu Source Type: research
Swine Influenza Virus Infection Decreases the Protective Immune Responses of Subunit Vaccine Against Porcine Circovirus Type 2
This study indicates that SIV infection decreases the protective immune responses of vaccine S against PCV2. The macrophage polarization induced by SIV infection might facilitate decreased immune responses to vaccine S, which provides new insight into vaccine evaluation and a reference for the analysis of immunization failure. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - December 24, 2021 Category: Microbiology Source Type: research
