TWiV 634: 1000 hours of the sunlight of TWiV
TWiV reviews a new H1N1 swine influenza virus from China with pandemic potential, Ad5 vectored SARS-CoV-2 oral vaccine candidate, Operation Warp Speed vaccine candidates, FDA guidance on vaccine approval, and answer listener email. Click arrow to playDownload TWiV 634 (72 MB .mp3, 120 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - July 2, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology adenovirus COVID-19 FDA vaccine guidance Operation Warp Speed SARS-CoV-2 viral viruses Source Type: blogs

The False Choice Between Science And Economics
This article originally appeared on The Bulwark here. The post The False Choice Between Science And Economics appeared first on The Health Care Blog. (Source: The Health Care Blog)
Source: The Health Care Blog - May 1, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy David Shaywitz Source Type: blogs

Is Trump Acting Presidential?
Thomas A. FireyAmong the criticisms President Trump has received over his handling of COVID-19, one is that he ’s playing politics with disaster aid. TheDenver Post recently charged that he “is treating life‐​saving medical equipment as emoluments he can dole out as favors to loyalists.” Michigan Gov.Gretchen Whitmer has claimed that “vendors are being told not to send stuff here to Michigan.” Trump himself has said the governors “have to treat us well also” in order to get what they need.So far, evidence of actual favoritism is mixed. A Washington Post review of federal distribution of ventilators, ...
Source: Cato-at-liberty - April 23, 2020 Category: American Health Authors: Thomas A. Firey Source Type: blogs

Birds, Pigs and Silent VIP ’s
It has become a tragic fact that every year the flu season brings an immense burden on health care services and now has dozens of subtypes cataloged, from ‘swine flu’ to ‘bird flu’ to ‘Asian flu’ and beyond. Typically, between late Fall and early Spring, over the last ten years, the United States alone has suffered hundreds of thousands of hospitalizations and tens of thousands of deaths across all ages [1]. But shortly after the turn of the century the ‘Spanish Flu’ pandemic of 1918 to 1920 was different in the extreme, and like every disease or virus did not discriminate on age, gender, race, even specie...
Source: GIDEON blog - March 4, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: General Source Type: blogs

TWiV 582: This little virus went to market
TWiV provides updates on the new coronavirus causing respiratory disease in China, the current influenza season, and the epidemic of African swine fever, including determination of the three-dimensional structure of the virus particle. Click arrow to play Download TWiV 582 (71 MB .mp3, 118 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - January 12, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology african swine fever virus capsid China coronavirus cryo-electron micrography giant virus Huanan Fish Market influenza influenza excess mortality influenza like illness influenza vaccine pig three dimensional Source Type: blogs

Beyond Vaccination: New Measures Needed to Protect Hospitals and the Public Against the Flu
By MARC M. BEUTTLER, MD Every year at this time, you hear warnings that flu season has arrived. New data from the CDC indicates the season is far from over. So, you are urged by health authorities to get a flu shot. What you may not realize is how the flu can affect the hospitals you and your loved ones rely on for care.   In January, the large urban hospital where I am an intern faced the worst flu outbreak it has ever seen. Nearly 100 staff members tested positive for the flu. Residents assigned to back-up coverage were called to work daily to supplement the dwindling ranks of the sick. Every hospital vis...
Source: The Health Care Blog - March 22, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Hospitals Medical Practice Marc Beuttler Vaccination Source Type: blogs

AAP Bronchiolitis Guidelines a Mismatch with Clinical Practice
​I recently met with a group from our children's hospital to standardize the hospital management of bronchiolitis according to the latest American Academy of Pediatrics guidelines. (Pediatrics 2014;134[5]:e1474; http://bit.ly/2QIGbMX.) Unfortunately, these guidelines seem to cause confusion for experienced and inexperienced emergency physicians alike.This confusion comes from the guidelines raising unaddressed issues and new questions, most importantly not tackling important aspects of frontline clinical practice. These guidelines were developed with the best evidence currently available, and their application mo...
Source: M2E Too! Mellick's Multimedia EduBlog - December 4, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Is it Time for Your Flu Shot or Extra Nutrition?
Conclusions Flu vaccinations have caused serious disease and death, including miscarriages, Guillain-Barré Syndrome, and influenza. The influenza vaccine has been reported to be effective zero to 50% of the time. Safer practices exist to build one’s immune system and stay healthy this winter. Some suggestions for avoiding illness include eating nutrient-dense foods, taking vitamins C and D, resting and detoxifying through Epsom salt baths. References: http://articles.mercola.com…flu-vaccination-epa-safety-limit-for-mercury.aspx http://www.greenmedinfo.com/blog/deadly-truth-about-flu-vaccines… http://healthi...
Source: vactruth.com - January 10, 2017 Category: Allergy & Immunology Authors: Michelle Goldstein Tags: Logical Michelle Goldstein Physical Recent Articles Top Picks flu shot influenza truth about vaccines Vaccine Death Source Type: blogs

TWiV 396: Influenza viruses with Peter Palese
Vincent speaks with Peter Palese about his illustrious career in virology, from early work on neuraminidases to universal influenza virus vaccines, on episode #396 of the science show This Week in Virology. You can find TWiV #396 at microbe.tv/twiv, or listen below. Click arrow to play Download TWiV 396 (54 MB .mp3, 74 min) Subscribe (free): iTunes, RSS, email (Source: virology blog)
Source: virology blog - July 3, 2016 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology aerosol transmission ferret Flu gain of function H5N1 influenza influenza virus neuraminidase relenza swine flu tamiflu universal vaccine viral viruses Source Type: blogs

TWiV 296: Influenza viruses with Peter Palese
Vincent speaks with Peter Palese about his illustrious career in virology, from early work on neuraminidases to universal influenza virus vaccines, on episode #396 of the science show This Week in Virology. You can find TWiV #396 at microbe.tv/twiv, or listen below. Click arrow to play Download TWiV 396 (54 MB .mp3, 74 min) Subscribe (free): iTunes, RSS, email (Source: virology blog)
Source: virology blog - July 3, 2016 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology aerosol transmission ferret Flu gain of function H5N1 influenza influenza virus neuraminidase relenza swine flu tamiflu universal vaccine viral viruses Source Type: blogs

You Won’t Believe Which Big-Name Groups are Opposed to Flu Vaccine Mandates
Conclusion Millions of people are refusing vaccines, in record numbers, as they realize that vaccines are dangerous and ineffective. Now, unions and professional organizations are joining the ranks of anti-vaxers, at least with regard to mandatory vaccination. Those organizations value their members and know that they deserve choices about their bodies and their health care. In return, those groups will be rewarded with a collectively healthier, more innovative work force, because their employees will not be forced to receive injections laced with toxic chemicals. Their employees will also know their ideas and opinions are...
Source: vactruth.com - January 17, 2015 Category: Allergy & Immunology Authors: Missy Fluegge Tags: Missy Fluegge Top Stories American Medical Association (AMA) Mandatory Vaccination National Childhood Vaccine Injury Act truth about vaccines Vaccine Adverse Events Reporting System (VAERS) Source Type: blogs

Virology question of the week: why a segmented viral genome?
This week’s virology question comes from Eric, who writes: I’m working on an MPH and in one of my classes we are currently studying the influenza virus. I’d forgotten that the genome is in 8 separate parts. Curious, I’ve been searching but can’t find any information as to why that is? What evolutionary advantage is conferred by having a segmented genome? Terrific question! Here is my reply: It’s always hard to have answers to ‘why’ questions such as yours. We answer these questions from a human-centric view of what viruses ‘need’. We might not be right. But I’d guess there ...
Source: virology blog - April 22, 2014 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information evolution gene expression influenza reassortment segmented genome viral virus Source Type: blogs

Changing influenza virus neuraminidase into a receptor binding protein
The hemagglutinin (HA) and neuraminidase (NA) glycoproteins of the influenza virus particle serve distinct functions during infection. The HA binds sialic acid-containing cellular receptors and mediates fusion of the viral and cell membranes, while the NA removes sialic acids from glycoproteins. Apparently this division of labor is not absolute: influenza viruses have been identified with NA molecules that serve as receptor binding proteins. An influenza virus was created that could not bind sialic acid by introducing multiple mutations into the HA gene. This mutant virus was not expected to be infectious, but nevertheless...
Source: virology blog - November 21, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information evolution HA hemagglutinin influenza mutation NA neuraminidase receptor binding sialidase tamiflu viral virus Source Type: blogs

Dr James LeFanu writes
There is rather more than is immediately apparent in the recent grudging acknowledgement that the swine flu vaccine increased the risk of the serious sleeping disorder narcolepsy fourteen-fold – and that those affected (mainly children) are entitled to compensation.As many will recall, the threatened swine flu “pandemic” of 2009 proved something of a non-event, with only 10 per cent of the predicted number of cases and a miniscule mortality rate of 0.0005 per cent.This discrepancy between the dire warnings and what turned out to be among the mildest flu outbreaks of the past 100 years prompted an inquiry by...
Source: PharmaGossip - November 18, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs