The impact of non-caloric artificial sweetener aspartame on female reproductive system in mice model
CONCLUSION: Non-nutritive artificial sweeteners including aspartame negatively impact the function of ovaries and feedback mechanism of reproductive hormones by affecting the hypothalamic-pituitary-gonadal axis. In light of present findings the aspartame negatively impacted the reproductive system of female mice. More studies are required to identify the molecular mechanism and the pathways involved.PMID:37580716 | PMC:PMC10424399 | DOI:10.1186/s12958-023-01115-4 (Source: Reproductive Biology)
Source: Reproductive Biology - August 14, 2023 Category: Reproduction Medicine Authors: Ab Qayoom Naik Tabassum Zafar Vinoy K Shrivastava Source Type: research

The impact of non-caloric artificial sweetener aspartame on female reproductive system in mice model
Artificial sweeteners, used as sugar substitutes have found their ways into almost all the food items due to the notion that they are non-caloric. Aspartame is used in numerous food products throughout the wor... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - August 14, 2023 Category: Endocrinology Authors: Ab Qayoom Naik, Tabassum Zafar and Vinoy K Shrivastava Tags: Research Source Type: research

Sensory Systems for Sugar-Induced Cephalic Phase Insulin Release
AbstractPurpose of ReviewThis review aims to discuss and summarize the peripheral sensory mechanisms involved in the induction of the early phase of insulin release, known as cephalic phase insulin release (CPIR), triggered by stimuli related to food, particularly sugars.Recent FindingsAt least, two distinct systems on the tongue are responsible for detecting oral sugars. The first system involves the G-protein-coupled receptor Tas1r2/Tas1r3, which can detect not only sugars but also artificial sweeteners and sweet proteins. The second system relies on glucose transporters, specifically recognize and transport monosacchari...
Source: Current Oral Health Reports - August 12, 2023 Category: Dentistry Source Type: research

The association of obesity-related dietary patterns and main food groups derived by reduced-rank regression with cardiovascular diseases incidence and all-cause mortality: findings from 116,711 adults
ConclusionsWe developed obesity-related DPs prospectively associated with increased risks of CVD and all-cause mortality. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 11, 2023 Category: Nutrition Source Type: research

BETA-CARYOPHYLLENE MITIGATES THE COGNITIVE IMPAIRMENT CAUSED BY REPEATED EXPOSURE TO ASPARTAME IN RATS: PUTATIVE ROLE OF BDNF - TrKB SIGNALING PATHWAY AND ACETYLCHOLINESTERASE ACTIVITY
In conclusion, BCP protected against ASP-induced memory impairment. AChE activity and the BDNF/TrkB signaling pathway seem to be potential targets of BCP modulatory role in this study.PMID:37558167 | DOI:10.1016/j.bbr.2023.114615 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - August 9, 2023 Category: Neurology Authors: Érica Vanessa Furlan Rosa Alice Rosa DA Silveira Marcel Henrique Marcondes Sari Tuane Bazanella Sampaio Jamila Trindade Dos Santos Sabrina Grendene M üller Michele Rechia Fighera Luiz Fernando Freire Royes Cristina Wayne Nogueira Mauro Schneider Oliveir Source Type: research

BETA-CARYOPHYLLENE MITIGATES THE COGNITIVE IMPAIRMENT CAUSED BY REPEATED EXPOSURE TO ASPARTAME IN RATS: PUTATIVE ROLE OF BDNF - TrKB SIGNALING PATHWAY AND ACETYLCHOLINESTERASE ACTIVITY
In conclusion, BCP protected against ASP-induced memory impairment. AChE activity and the BDNF/TrkB signaling pathway seem to be potential targets of BCP modulatory role in this study.PMID:37558167 | DOI:10.1016/j.bbr.2023.114615 (Source: Brain Research)
Source: Brain Research - August 9, 2023 Category: Neurology Authors: Érica Vanessa Furlan Rosa Alice Rosa DA Silveira Marcel Henrique Marcondes Sari Tuane Bazanella Sampaio Jamila Trindade Dos Santos Sabrina Grendene M üller Michele Rechia Fighera Luiz Fernando Freire Royes Cristina Wayne Nogueira Mauro Schneider Oliveir Source Type: research

BETA-CARYOPHYLLENE MITIGATES THE COGNITIVE IMPAIRMENT CAUSED BY REPEATED EXPOSURE TO ASPARTAME IN RATS: PUTATIVE ROLE OF BDNF - TrKB SIGNALING PATHWAY AND ACETYLCHOLINESTERASE ACTIVITY
In conclusion, BCP protected against ASP-induced memory impairment. AChE activity and the BDNF/TrkB signaling pathway seem to be potential targets of BCP modulatory role in this study.PMID:37558167 | DOI:10.1016/j.bbr.2023.114615 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - August 9, 2023 Category: Neurology Authors: Érica Vanessa Furlan Rosa Alice Rosa DA Silveira Marcel Henrique Marcondes Sari Tuane Bazanella Sampaio Jamila Trindade Dos Santos Sabrina Grendene M üller Michele Rechia Fighera Luiz Fernando Freire Royes Cristina Wayne Nogueira Mauro Schneider Oliveir Source Type: research

BETA-CARYOPHYLLENE MITIGATES THE COGNITIVE IMPAIRMENT CAUSED BY REPEATED EXPOSURE TO ASPARTAME IN RATS: PUTATIVE ROLE OF BDNF - TrKB SIGNALING PATHWAY AND ACETYLCHOLINESTERASE ACTIVITY
In conclusion, BCP protected against ASP-induced memory impairment. AChE activity and the BDNF/TrkB signaling pathway seem to be potential targets of BCP modulatory role in this study.PMID:37558167 | DOI:10.1016/j.bbr.2023.114615 (Source: Brain Research)
Source: Brain Research - August 9, 2023 Category: Neurology Authors: Érica Vanessa Furlan Rosa Alice Rosa DA Silveira Marcel Henrique Marcondes Sari Tuane Bazanella Sampaio Jamila Trindade Dos Santos Sabrina Grendene M üller Michele Rechia Fighera Luiz Fernando Freire Royes Cristina Wayne Nogueira Mauro Schneider Oliveir Source Type: research

BETA-CARYOPHYLLENE MITIGATES THE COGNITIVE IMPAIRMENT CAUSED BY REPEATED EXPOSURE TO ASPARTAME IN RATS: PUTATIVE ROLE OF BDNF - TrKB SIGNALING PATHWAY AND ACETYLCHOLINESTERASE ACTIVITY
In conclusion, BCP protected against ASP-induced memory impairment. AChE activity and the BDNF/TrkB signaling pathway seem to be potential targets of BCP modulatory role in this study.PMID:37558167 | DOI:10.1016/j.bbr.2023.114615 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - August 9, 2023 Category: Neurology Authors: Érica Vanessa Furlan Rosa Alice Rosa DA Silveira Marcel Henrique Marcondes Sari Tuane Bazanella Sampaio Jamila Trindade Dos Santos Sabrina Grendene M üller Michele Rechia Fighera Luiz Fernando Freire Royes Cristina Wayne Nogueira Mauro Schneider Oliveir Source Type: research

Low-no-calorie sweeteners exert marked compound-specific impact on the human gut microbiota < em > ex vivo < /em >
This study investigated how a range of sweeteners [tagatose (TA)/maltitol (MA)/sorbitol (SO)/stevia (ST)/sucralose (SU)/acesulfame K (ACK)] impact the gut microbiota of T2D subjects and healthy human adults using the ex vivo SIFR® technology (n = 12). The cohort covered clinically relevant interpersonal and T2D-related differences. ACK/SU remained intact while not impacting microbial composition and metabolite production. In contrast, TA/SO and ST/MA were respectively readily and gradually fermented. ST and particularly TA/SO/MA increased bacterial density and SCFA production product-specifically: SO increased acetate (âˆ...
Source: International Journal of Food Sciences and Nutrition - August 4, 2023 Category: Nutrition Authors: Pieter Van den Abbeele Jonas Poppe Stef Deyaert Ieva Laurie Thorsten Klaus Otto Gravert Anna Abrahamsson Aur élien Baudot Kavita Karnik Davide Risso Source Type: research

Nutritive/non-nutritive sweeteners and high fat diet contribute to dysregulation of sweet taste receptors and metabolic derangements in oral, intestinal and central nervous tissues
ConclusionsLong-term consumption of whether nutritive sweeteners or non-nutritive sweeteners combined with high fat diet contribute to dysregulation of sweet taste receptor expression in oral, intestinal and central nervous tissues. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 3, 2023 Category: Nutrition Source Type: research

Implementing front-of-pack nutrition warning labels in mexico: important lessons for low and middle-income countries
CONCLUSION: Early success in implementing the new FOPNL system in Mexico was the result of an inclusive and participatory regulatory process dedicated to maintaining public health advances, local and international health advocacy support, and continued monitoring. Other countries proposing and enacting FOPNL should learn from the Mexican experience to maintain scientifically proven best practices, counter industry barriers and minimize delays in implementation.PMID:37519233 | DOI:10.1017/S1368980023001441 (Source: Public Health Nutrition)
Source: Public Health Nutrition - July 31, 2023 Category: International Medicine & Public Health Authors: Eric Crosbie Margarita Gabriela Otero Alvarez Michelle Cao Lesly Samara Vejar Renteria Estefania Rodriguez Ana Larra ñaga Flota Angela Carriedo Source Type: research