Feasibility and acceptability of miracle fruit application prior to the consumption of sour-tasting foods as a weight-loss strategy in adults with diabetes or prediabetes: A randomized crossover trial
Appetite. 2023 Sep 17:107046. doi: 10.1016/j.appet.2023.107046. Online ahead of print.ABSTRACTMiracle fruit (MF) has emerged as a promising option for healthy noncaloric sweeteners due to its sour-to-sweet taste-modifying effects and high antioxidant activity. We aimed to examine the feasibility and acceptability of using MF as a weight-loss strategy for individuals with diabetes or prediabetes. Fifty Korean-American men and women (25 participants each) aged 45-75 years with diabetes or prediabetes were recruited in this study. They participated in a randomized placebo-controlled crossover trial where they took the assigne...
Source: Appetite - September 19, 2023 Category: Nutrition Authors: Sung Eun Choi Taehwan Park Source Type: research
Feasibility and acceptability of miracle fruit application prior to the consumption of sour-tasting foods as a weight-loss strategy in adults with diabetes or prediabetes: A randomized crossover trial
Appetite. 2023 Sep 17:107046. doi: 10.1016/j.appet.2023.107046. Online ahead of print.ABSTRACTMiracle fruit (MF) has emerged as a promising option for healthy noncaloric sweeteners due to its sour-to-sweet taste-modifying effects and high antioxidant activity. We aimed to examine the feasibility and acceptability of using MF as a weight-loss strategy for individuals with diabetes or prediabetes. Fifty Korean-American men and women (25 participants each) aged 45-75 years with diabetes or prediabetes were recruited in this study. They participated in a randomized placebo-controlled crossover trial where they took the assigne...
Source: Appetite - September 19, 2023 Category: Nutrition Authors: Sung Eun Choi Taehwan Park Source Type: research
Improvement and Regulation of Steviol Glycoside Biosynthesis in Stevia rebaudiana Bertoni
Gene. 2023 Sep 16:147809. doi: 10.1016/j.gene.2023.147809. Online ahead of print.ABSTRACTStevia rebaudiana Bertoni is a natural sweetener plant that is progressively used not only for its sweetening properties but also for its medicinal properties. The plant contains steviol glycoside (SG) which is reported to be up to 300 times sweeter than sucrose. The plant is said to have no side effects on human health and has been approved by FDA. On the basis of previous studies and available databases, this review discusses the extensive understanding of the different approaches for enhancements of SG in S. rebaudiana. To improve t...
Source: Gene - September 18, 2023 Category: Genetics & Stem Cells Authors: Pritom Biswas Ankita Kumari Arpan Modi Nitish Kumar Source Type: research
Improvement and Regulation of Steviol Glycoside Biosynthesis in Stevia rebaudiana Bertoni
Gene. 2023 Sep 16:147809. doi: 10.1016/j.gene.2023.147809. Online ahead of print.ABSTRACTStevia rebaudiana Bertoni is a natural sweetener plant that is progressively used not only for its sweetening properties but also for its medicinal properties. The plant contains steviol glycoside (SG) which is reported to be up to 300 times sweeter than sucrose. The plant is said to have no side effects on human health and has been approved by FDA. On the basis of previous studies and available databases, this review discusses the extensive understanding of the different approaches for enhancements of SG in S. rebaudiana. To improve t...
Source: Gene - September 18, 2023 Category: Genetics & Stem Cells Authors: Pritom Biswas Ankita Kumari Arpan Modi Nitish Kumar Source Type: research
WHO guideline on the use of non-sugar sweeteners: a need for reconsideration
European Journal of Clinical Nutrition, Published online: 18 September 2023; doi:10.1038/s41430-023-01314-7WHO guideline on the use of non-sugar sweeteners: a need for reconsideration (Source: European Journal of Clinical Nutrition)
Source: European Journal of Clinical Nutrition - September 18, 2023 Category: Nutrition Authors: Tauseef A. Khan Jennifer J. Lee Sabrina Ayoub-Charette Jarvis Clyde Noronha Nema McGlynn Laura Chiavaroli John L. Sievenpiper Source Type: research
Modeling the structure of the transmembrane domain of T1R3, a subunit of the sweet taste receptor, with neohesperidin dihydrochalcone using molecular dynamics simulation
This study involved the creation of an NHDC-docked model of T1R3 TMD through mutational analyses followed by in silico simulations. When certain NHDC derivatives were docked to the model, His7345.44 was demonstrated to play a crucial role in activating T1R3 TMD. The NHDC-docked model was then compared with a lactisole-docked inactive form, several residues were characterized as important for the recognition of NHDC; however, most of them were distinct from those of lactisole. Residues such as His6413.33 and Gln7947.38 were found to be oriented differently. This study provides useful information that will facilitate the des...
Source: Bioscience, Biotechnology, and Biochemistry - September 15, 2023 Category: Biochemistry Authors: Tomoya Nakagita Takumi Matsuya Masataka Narukawa Takuya Kobayashi Takatsugu Hirokawa Takumi Misaka Source Type: research
Modeling the structure of the transmembrane domain of T1R3, a subunit of the sweet taste receptor, with neohesperidin dihydrochalcone using molecular dynamics simulation
This study involved the creation of an NHDC-docked model of T1R3 TMD through mutational analyses followed by in silico simulations. When certain NHDC derivatives were docked to the model, His7345.44 was demonstrated to play a crucial role in activating T1R3 TMD. The NHDC-docked model was then compared with a lactisole-docked inactive form, several residues were characterized as important for the recognition of NHDC; however, most of them were distinct from those of lactisole. Residues such as His6413.33 and Gln7947.38 were found to be oriented differently. This study provides useful information that will facilitate the des...
Source: Bioscience, Biotechnology, and Biochemistry - September 15, 2023 Category: Biochemistry Authors: Tomoya Nakagita Takumi Matsuya Masataka Narukawa Takuya Kobayashi Takatsugu Hirokawa Takumi Misaka Source Type: research
Modeling the structure of the transmembrane domain of T1R3, a subunit of the sweet taste receptor, with neohesperidin dihydrochalcone using molecular dynamics simulation
This study involved the creation of an NHDC-docked model of T1R3 TMD through mutational analyses followed by in silico simulations. When certain NHDC derivatives were docked to the model, His7345.44 was demonstrated to play a crucial role in activating T1R3 TMD. The NHDC-docked model was then compared with a lactisole-docked inactive form, several residues were characterized as important for the recognition of NHDC; however, most of them were distinct from those of lactisole. Residues such as His6413.33 and Gln7947.38 were found to be oriented differently. This study provides useful information that will facilitate the des...
Source: Bioscience, Biotechnology, and Biochemistry - September 15, 2023 Category: Biochemistry Authors: Tomoya Nakagita Takumi Matsuya Masataka Narukawa Takuya Kobayashi Takatsugu Hirokawa Takumi Misaka Source Type: research
Molecules, Vol. 28, Pages 6618: The Identity and Mineral Composition of Natural, Plant-Derived and Artificial Sweeteners
Pohl
The qualitative X-ray phase analysis of natural and artificial food sweeteners was applied to trace the authenticity of such food additives. The mineral composition of different sweeteners commonly added to foods was studied to estimate their mineral profiles and assess the risk related to the toxic elements intake caused by sweetener consumption. The concentration of twenty elements (Ag, Al, B, Ba, Bi, Ca, Cd, Co, Cr, Cu, Fe, Mg, Mn, Mo, Ni, Pb, Sr, Ti, V, and Zn) was measured using the inductively coupled plasma–optical emission spectroscopy (ICP-OES) method after the representative samples were we...
Source: Molecules - September 14, 2023 Category: Chemistry Authors: Anna Le śniewicz Maja We łna Anna Szymczycha-Madeja Pawe ł Pohl Tags: Article Source Type: research
Molecules, Vol. 28, Pages 6594: Sugar Alcohol Sweetener Production by Yarrowia lipolytica Grown in Media Containing Glycerol
Rymowicz
Most of the world’s annual production of mannitol is by chemical means, but, due to increasing demand for natural sweeteners, alternative production methods are being sought. The aim of the study was to screen Yarrowia lipolytica yeast strains and select culture conditions for the efficient and selective biosynthesis of mannitol from glycerol. From 21 strains examined in the shake-flask culture for mannitol biosynthesis from glycerol (100 g/L), three strains were selected—S2, S3, and S4—and further evaluated in batch bioreactor cultures with technical and raw glycerol ...
Source: Molecules - September 13, 2023 Category: Chemistry Authors: Piotr Juszczyk Anita Rywi ńska Julia Kosicka Ludwika Tomaszewska-Hetman Waldemar Rymowicz Tags: Article Source Type: research
Simultaneous determination of nine high-intensity sweeteners in liquid and powder tabletop sweeteners
. (Source: Food Additives and Contaminants Part A)
Source: Food Additives and Contaminants Part A - September 11, 2023 Category: Food Science Authors: Ícaro Gouvea Nicoluci Beatriz Scardua da Silva Patricia Aparecida de Campos Braga Adriana Pavesi Arisseto Bragotto Source Type: research
High ‐Sucrose Diet Accelerates Arthritis Progression in a Collagen‐Induced Rheumatoid Arthritis Model
ConclusionsThese findings suggest that excessive sucrose consumption causes hepatic fibrosis and inflammation, contributing to the pathophysiology of RA. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - September 9, 2023 Category: Food Science Authors: Yunhui Min,
Yunji Heo,
Fang Feng,
Dahye Kim,
Mangeun Kim,
Jiwon Yang,
Hyo Jin Kim,
Youngheun Jee,
Mrinmoy Ghosh,
Inhae Kang,
Young ‐Ok Son Tags: Research Article Source Type: research
Sweeteners in Brazilian processed foods and beverages: prevalence, profile and concomitant addition of sugars and nutritional claims
. (Source: Food Additives and Contaminants Part A)
Source: Food Additives and Contaminants Part A - September 8, 2023 Category: Food Science Authors: Roberto Cesar Santos de Sousa Maria Beatriz Abreu Gloria Source Type: research
Influence of sucralose, acesulfame-k, and their mixture on brain's fish: A study of behavior, oxidative damage, and acetylcholinesterase activity in Daniorerio
Chemosphere. 2023 Aug 23:139928. doi: 10.1016/j.chemosphere.2023.139928. Online ahead of print.ABSTRACTSucralose (SUC) and acesulfame-k (ACE-K) are widely used artificial sweeteners worldwide; however, they are frequently detected in aquatic environments due to their low metabolism and inadequate removal during wastewater treatment. The harmful effects of these compounds on hydrobionts have yet to be fully understood, as data on their toxicity is limited and inconclusive. This research aimed to determine the impact of SUC (50, 75, 125 μg/L) and ACE-K (50, 75, 125 μg/L), individually and in combination, on fish's swimming...
Source: Chemosphere - August 25, 2023 Category: Chemistry Authors: Karla Col ín-García Gustavo Axel Elizalde-Vel ázquez Leobardo Manuel G ómez-Oliván Sandra Garc ía-Medina Source Type: research
Influence of sucralose, acesulfame-k, and their mixture on brain's fish: A study of behavior, oxidative damage, and acetylcholinesterase activity in Daniorerio
Chemosphere. 2023 Aug 23:139928. doi: 10.1016/j.chemosphere.2023.139928. Online ahead of print.ABSTRACTSucralose (SUC) and acesulfame-k (ACE-K) are widely used artificial sweeteners worldwide; however, they are frequently detected in aquatic environments due to their low metabolism and inadequate removal during wastewater treatment. The harmful effects of these compounds on hydrobionts have yet to be fully understood, as data on their toxicity is limited and inconclusive. This research aimed to determine the impact of SUC (50, 75, 125 μg/L) and ACE-K (50, 75, 125 μg/L), individually and in combination, on fish's swimming...
Source: Chemosphere - August 25, 2023 Category: Chemistry Authors: Karla Col ín-García Gustavo Axel Elizalde-Vel ázquez Leobardo Manuel G ómez-Oliván Sandra Garc ía-Medina Source Type: research
