Influence of sucralose, acesulfame-k, and their mixture on brain's fish: A study of behavior, oxidative damage, and acetylcholinesterase activity in Daniorerio
Chemosphere. 2023 Aug 23:139928. doi: 10.1016/j.chemosphere.2023.139928. Online ahead of print.ABSTRACTSucralose (SUC) and acesulfame-k (ACE-K) are widely used artificial sweeteners worldwide; however, they are frequently detected in aquatic environments due to their low metabolism and inadequate removal during wastewater treatment. The harmful effects of these compounds on hydrobionts have yet to be fully understood, as data on their toxicity is limited and inconclusive. This research aimed to determine the impact of SUC (50, 75, 125 μg/L) and ACE-K (50, 75, 125 μg/L), individually and in combination, on fish's swimming...
Source: Chemosphere - August 25, 2023 Category: Chemistry Authors: Karla Col ín-García Gustavo Axel Elizalde-Vel ázquez Leobardo Manuel G ómez-Oliván Sandra Garc ía-Medina Source Type: research
Cardiotoxic and neurobehavioral effects of sucralose and acesulfame in Daphnia: Toward understanding ecological impacts of artificial sweeteners
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Aug 22:109733. doi: 10.1016/j.cbpc.2023.109733. Online ahead of print.ABSTRACTArtificial sweeteners are widely used in food and pharmaceuticals, but their stability and persistence raise concerns about their impact on aquatic life. Although standard toxicity tests do not reveal lethal effects, recent studies suggest a potential neurotoxic mode of action. Using environmentally relevant concentrations, we assessed the effects of sucralose and acesulfame, common sugar substitutes, on Daphnia magna focusing on biochemical (acetylcholinesterase activity; AChE), physiological (heart...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - August 24, 2023 Category: Biochemistry Authors: Ann-Kristin Eriksson Wiklund Xueli Guo Elena Gorokhova Source Type: research
News Brief: The WHO warns against using artificial sweeteners
Am J Nurs. 2023 Sep 1;123(9):16. doi: 10.1097/01.NAJ.0000978116.14894.e4.NO ABSTRACTPMID:37615459 | DOI:10.1097/01.NAJ.0000978116.14894.e4 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - August 24, 2023 Category: Nursing Source Type: research
Cardiotoxic and neurobehavioral effects of sucralose and acesulfame in Daphnia: Toward understanding ecological impacts of artificial sweeteners
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Aug 22:109733. doi: 10.1016/j.cbpc.2023.109733. Online ahead of print.ABSTRACTArtificial sweeteners are widely used in food and pharmaceuticals, but their stability and persistence raise concerns about their impact on aquatic life. Although standard toxicity tests do not reveal lethal effects, recent studies suggest a potential neurotoxic mode of action. Using environmentally relevant concentrations, we assessed the effects of sucralose and acesulfame, common sugar substitutes, on Daphnia magna focusing on biochemical (acetylcholinesterase activity; AChE), physiological (heart...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - August 24, 2023 Category: Biochemistry Authors: Ann-Kristin Eriksson Wiklund Xueli Guo Elena Gorokhova Source Type: research
News Brief: The WHO warns against using artificial sweeteners
Am J Nurs. 2023 Sep 1;123(9):16. doi: 10.1097/01.NAJ.0000978116.14894.e4.NO ABSTRACTPMID:37615459 | DOI:10.1097/01.NAJ.0000978116.14894.e4 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - August 24, 2023 Category: Nursing Source Type: research
Cardiotoxic and neurobehavioral effects of sucralose and acesulfame in Daphnia: Toward understanding ecological impacts of artificial sweeteners
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Aug 22:109733. doi: 10.1016/j.cbpc.2023.109733. Online ahead of print.ABSTRACTArtificial sweeteners are widely used in food and pharmaceuticals, but their stability and persistence raise concerns about their impact on aquatic life. Although standard toxicity tests do not reveal lethal effects, recent studies suggest a potential neurotoxic mode of action. Using environmentally relevant concentrations, we assessed the effects of sucralose and acesulfame, common sugar substitutes, on Daphnia magna focusing on biochemical (acetylcholinesterase activity; AChE), physiological (heart...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - August 24, 2023 Category: Biochemistry Authors: Ann-Kristin Eriksson Wiklund Xueli Guo Elena Gorokhova Source Type: research
News Brief: The WHO warns against using artificial sweeteners
Am J Nurs. 2023 Sep 1;123(9):16. doi: 10.1097/01.NAJ.0000978116.14894.e4.NO ABSTRACTPMID:37615459 | DOI:10.1097/01.NAJ.0000978116.14894.e4 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - August 24, 2023 Category: Nursing Source Type: research
Cardiotoxic and neurobehavioral effects of sucralose and acesulfame in Daphnia: Toward understanding ecological impacts of artificial sweeteners
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Aug 22:109733. doi: 10.1016/j.cbpc.2023.109733. Online ahead of print.ABSTRACTArtificial sweeteners are widely used in food and pharmaceuticals, but their stability and persistence raise concerns about their impact on aquatic life. Although standard toxicity tests do not reveal lethal effects, recent studies suggest a potential neurotoxic mode of action. Using environmentally relevant concentrations, we assessed the effects of sucralose and acesulfame, common sugar substitutes, on Daphnia magna focusing on biochemical (acetylcholinesterase activity; AChE), physiological (heart...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - August 24, 2023 Category: Biochemistry Authors: Ann-Kristin Eriksson Wiklund Xueli Guo Elena Gorokhova Source Type: research
News Brief: The WHO warns against using artificial sweeteners
Am J Nurs. 2023 Sep 1;123(9):16. doi: 10.1097/01.NAJ.0000978116.14894.e4.NO ABSTRACTPMID:37615459 | DOI:10.1097/01.NAJ.0000978116.14894.e4 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - August 24, 2023 Category: Nursing Source Type: research
Cardiotoxic and neurobehavioral effects of sucralose and acesulfame in Daphnia: Toward understanding ecological impacts of artificial sweeteners
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Aug 22:109733. doi: 10.1016/j.cbpc.2023.109733. Online ahead of print.ABSTRACTArtificial sweeteners are widely used in food and pharmaceuticals, but their stability and persistence raise concerns about their impact on aquatic life. Although standard toxicity tests do not reveal lethal effects, recent studies suggest a potential neurotoxic mode of action. Using environmentally relevant concentrations, we assessed the effects of sucralose and acesulfame, common sugar substitutes, on Daphnia magna focusing on biochemical (acetylcholinesterase activity; AChE), physiological (heart...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - August 24, 2023 Category: Biochemistry Authors: Ann-Kristin Eriksson Wiklund Xueli Guo Elena Gorokhova Source Type: research
News Brief: The WHO warns against using artificial sweeteners
Am J Nurs. 2023 Sep 1;123(9):16. doi: 10.1097/01.NAJ.0000978116.14894.e4.NO ABSTRACTPMID:37615459 | DOI:10.1097/01.NAJ.0000978116.14894.e4 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - August 24, 2023 Category: Nursing Source Type: research
Cardiotoxic and neurobehavioral effects of sucralose and acesulfame in Daphnia: Toward understanding ecological impacts of artificial sweeteners
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Aug 22:109733. doi: 10.1016/j.cbpc.2023.109733. Online ahead of print.ABSTRACTArtificial sweeteners are widely used in food and pharmaceuticals, but their stability and persistence raise concerns about their impact on aquatic life. Although standard toxicity tests do not reveal lethal effects, recent studies suggest a potential neurotoxic mode of action. Using environmentally relevant concentrations, we assessed the effects of sucralose and acesulfame, common sugar substitutes, on Daphnia magna focusing on biochemical (acetylcholinesterase activity; AChE), physiological (heart...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - August 24, 2023 Category: Biochemistry Authors: Ann-Kristin Eriksson Wiklund Xueli Guo Elena Gorokhova Source Type: research
News Brief: The WHO warns against using artificial sweeteners
Am J Nurs. 2023 Sep 1;123(9):16. doi: 10.1097/01.NAJ.0000978116.14894.e4.NO ABSTRACTPMID:37615459 | DOI:10.1097/01.NAJ.0000978116.14894.e4 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - August 24, 2023 Category: Nursing Source Type: research
Cardiotoxic and neurobehavioral effects of sucralose and acesulfame in Daphnia: Toward understanding ecological impacts of artificial sweeteners
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Aug 22;273:109733. doi: 10.1016/j.cbpc.2023.109733. Online ahead of print.ABSTRACTArtificial sweeteners are widely used in food and pharmaceuticals, but their stability and persistence raise concerns about their impact on aquatic life. Although standard toxicity tests do not reveal lethal effects, recent studies suggest a potential neurotoxic mode of action. Using environmentally relevant concentrations, we assessed the effects of sucralose and acesulfame, common sugar substitutes, on Daphnia magna focusing on biochemical (acetylcholinesterase activity; AChE), physiological (h...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - August 24, 2023 Category: Biochemistry Authors: Ann-Kristin Eriksson Wiklund Xueli Guo Elena Gorokhova Source Type: research
News Brief: The WHO warns against using artificial sweeteners
Am J Nurs. 2023 Sep 1;123(9):16. doi: 10.1097/01.NAJ.0000978116.14894.e4.NO ABSTRACTPMID:37615459 | DOI:10.1097/01.NAJ.0000978116.14894.e4 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - August 24, 2023 Category: Nursing Source Type: research
