Palatability Evaluation of Sulfamethoxazole/Trimethoprim with Sweetener Using the Two-Bottle Choice Test
In this study, a new two-bottle choice test was performed in rats to evaluate bitterness masking and determine the drug-to-sweetener ratio that significantly improves palatability. Sulfamethoxazole and trimethoprim were used as model bitter drugs, and sucralose was used as sweetener. The addition of sucralose and trimethoprim at a 0.13 : 1 ratio resulted in the greatest improvement in preference. This method is a useful new technique for evaluating the palatability of drug formulations.PMID:38044143 | DOI:10.1248/cpb.c23-00428 (Source: Chemical and Pharmaceutical Bulletin)
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Haruka Shinotsuka Naoya Mizutani Shohei Aikawa Go Kimura Source Type: research
Relative validity of habitual sugar and low/no-calorie sweetener consumption assessed by FFQ, multiple 24-h dietary recalls and urinary biomarkers: an observational study within the SWEET project
CONCLUSIONS: The validity of the FFQ against 24hRs for the assessment of sugars and LNCSB ranged from moderate to good. Comparing self-reports and urine excretions showed moderate agreement, but highlighted an important underestimation of LNCS exposure using the self-reports.PMID:38043866 | DOI:10.1016/j.ajcnut.2023.11.019 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - December 3, 2023 Category: Nutrition Authors: Marion E C Buso Hendriek C Boshuizen Novita D Naomi Walid Maho Marlies Diepeveen-de Bruin Michiel G J Balvers Jeanne H M de Vries Joanne A Harrold Jason C G Halford Anne Raben Edith J M Feskens Elske M Brouwer-Brolsma Source Type: research
Relative validity of habitual sugar and low/no-calorie sweetener consumption assessed by FFQ, multiple 24-h dietary recalls and urinary biomarkers: an observational study within the SWEET project
CONCLUSIONS: The validity of the FFQ against 24hRs for the assessment of sugars and LNCSB ranged from moderate to good. Comparing self-reports and urine excretions showed moderate agreement, but highlighted an important underestimation of LNCS exposure using the self-reports.PMID:38043866 | DOI:10.1016/j.ajcnut.2023.11.019 (Source: Am J Clin Nutr)
Source: Am J Clin Nutr - December 3, 2023 Category: Nutrition Authors: Marion E C Buso Hendriek C Boshuizen Novita D Naomi Walid Maho Marlies Diepeveen-de Bruin Michiel G J Balvers Jeanne H M de Vries Joanne A Harrold Jason C G Halford Anne Raben Edith J M Feskens Elske M Brouwer-Brolsma Source Type: research
Palatability Evaluation of Sulfamethoxazole/Trimethoprim with Sweetener Using the Two-Bottle Choice Test
In this study, a new two-bottle choice test was performed in rats to evaluate bitterness masking and determine the drug-to-sweetener ratio that significantly improves palatability. Sulfamethoxazole and trimethoprim were used as model bitter drugs, and sucralose was used as sweetener. The addition of sucralose and trimethoprim at a 0.13 : 1 ratio resulted in the greatest improvement in preference. This method is a useful new technique for evaluating the palatability of drug formulations.PMID:38044143 | DOI:10.1248/cpb.c23-00428 (Source: Chemical and Pharmaceutical Bulletin)
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Haruka Shinotsuka Naoya Mizutani Shohei Aikawa Go Kimura Source Type: research
Palatability Evaluation of Sulfamethoxazole/Trimethoprim with Sweetener Using the Two-Bottle Choice Test
In this study, a new two-bottle choice test was performed in rats to evaluate bitterness masking and determine the drug-to-sweetener ratio that significantly improves palatability. Sulfamethoxazole and trimethoprim were used as model bitter drugs, and sucralose was used as sweetener. The addition of sucralose and trimethoprim at a 0.13 : 1 ratio resulted in the greatest improvement in preference. This method is a useful new technique for evaluating the palatability of drug formulations.PMID:38044143 | DOI:10.1248/cpb.c23-00428 (Source: Chemical and Pharmaceutical Bulletin)
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Haruka Shinotsuka Naoya Mizutani Shohei Aikawa Go Kimura Source Type: research
Palatability Evaluation of Sulfamethoxazole/Trimethoprim with Sweetener Using the Two-Bottle Choice Test
In this study, a new two-bottle choice test was performed in rats to evaluate bitterness masking and determine the drug-to-sweetener ratio that significantly improves palatability. Sulfamethoxazole and trimethoprim were used as model bitter drugs, and sucralose was used as sweetener. The addition of sucralose and trimethoprim at a 0.13 : 1 ratio resulted in the greatest improvement in preference. This method is a useful new technique for evaluating the palatability of drug formulations.PMID:38044143 | DOI:10.1248/cpb.c23-00428 (Source: Chemical and Pharmaceutical Bulletin)
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Haruka Shinotsuka Naoya Mizutani Shohei Aikawa Go Kimura Source Type: research
Palatability Evaluation of Sulfamethoxazole/Trimethoprim with Sweetener Using the Two-Bottle Choice Test
In this study, a new two-bottle choice test was performed in rats to evaluate bitterness masking and determine the drug-to-sweetener ratio that significantly improves palatability. Sulfamethoxazole and trimethoprim were used as model bitter drugs, and sucralose was used as sweetener. The addition of sucralose and trimethoprim at a 0.13 : 1 ratio resulted in the greatest improvement in preference. This method is a useful new technique for evaluating the palatability of drug formulations.PMID:38044143 | DOI:10.1248/cpb.c23-00428 (Source: Chemical and Pharmaceutical Bulletin)
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Haruka Shinotsuka Naoya Mizutani Shohei Aikawa Go Kimura Source Type: research
Palatability Evaluation of Sulfamethoxazole/Trimethoprim with Sweetener Using the Two-Bottle Choice Test
In this study, a new two-bottle choice test was performed in rats to evaluate bitterness masking and determine the drug-to-sweetener ratio that significantly improves palatability. Sulfamethoxazole and trimethoprim were used as model bitter drugs, and sucralose was used as sweetener. The addition of sucralose and trimethoprim at a 0.13 : 1 ratio resulted in the greatest improvement in preference. This method is a useful new technique for evaluating the palatability of drug formulations.PMID:38044143 | DOI:10.1248/cpb.c23-00428 (Source: Chemical and Pharmaceutical Bulletin)
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Haruka Shinotsuka Naoya Mizutani Shohei Aikawa Go Kimura Source Type: research
Palatability Evaluation of Sulfamethoxazole/Trimethoprim with Sweetener Using the Two-Bottle Choice Test
In this study, a new two-bottle choice test was performed in rats to evaluate bitterness masking and determine the drug-to-sweetener ratio that significantly improves palatability. Sulfamethoxazole and trimethoprim were used as model bitter drugs, and sucralose was used as sweetener. The addition of sucralose and trimethoprim at a 0.13 : 1 ratio resulted in the greatest improvement in preference. This method is a useful new technique for evaluating the palatability of drug formulations.PMID:38044143 | DOI:10.1248/cpb.c23-00428 (Source: Chemical and Pharmaceutical Bulletin)
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Haruka Shinotsuka Naoya Mizutani Shohei Aikawa Go Kimura Source Type: research
Palatability Evaluation of Sulfamethoxazole/Trimethoprim with Sweetener Using the Two-Bottle Choice Test
In this study, a new two-bottle choice test was performed in rats to evaluate bitterness masking and determine the drug-to-sweetener ratio that significantly improves palatability. Sulfamethoxazole and trimethoprim were used as model bitter drugs, and sucralose was used as sweetener. The addition of sucralose and trimethoprim at a 0.13 : 1 ratio resulted in the greatest improvement in preference. This method is a useful new technique for evaluating the palatability of drug formulations.PMID:38044143 | DOI:10.1248/cpb.c23-00428 (Source: Chemical and Pharmaceutical Bulletin)
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Haruka Shinotsuka Naoya Mizutani Shohei Aikawa Go Kimura Source Type: research
Palatability Evaluation of Sulfamethoxazole/Trimethoprim with Sweetener Using the Two-Bottle Choice Test
In this study, a new two-bottle choice test was performed in rats to evaluate bitterness masking and determine the drug-to-sweetener ratio that significantly improves palatability. Sulfamethoxazole and trimethoprim were used as model bitter drugs, and sucralose was used as sweetener. The addition of sucralose and trimethoprim at a 0.13 : 1 ratio resulted in the greatest improvement in preference. This method is a useful new technique for evaluating the palatability of drug formulations.PMID:38044143 | DOI:10.1248/cpb.c23-00428 (Source: Chemical and Pharmaceutical Bulletin)
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Haruka Shinotsuka Naoya Mizutani Shohei Aikawa Go Kimura Source Type: research
Palatability Evaluation of Sulfamethoxazole/Trimethoprim with Sweetener Using the Two-Bottle Choice Test
In this study, a new two-bottle choice test was performed in rats to evaluate bitterness masking and determine the drug-to-sweetener ratio that significantly improves palatability. Sulfamethoxazole and trimethoprim were used as model bitter drugs, and sucralose was used as sweetener. The addition of sucralose and trimethoprim at a 0.13 : 1 ratio resulted in the greatest improvement in preference. This method is a useful new technique for evaluating the palatability of drug formulations.PMID:38044143 | DOI:10.1248/cpb.c23-00428 (Source: Chemical and Pharmaceutical Bulletin)
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Haruka Shinotsuka Naoya Mizutani Shohei Aikawa Go Kimura Source Type: research
Knowledge regarding natural sweeteners in young adults aged 21-40 years
Rationale: Industrialization and boom of packaged food industry has led to an increased consumption of various forms of natural sweeteners. Aim was to identify the knowledge levels regarding natural sweeteners in young adults aged 21-40 years. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: V. Singh, B.R. Samant, N. Sanwalka Source Type: research
Knowledge, attitude and practice regarding natural sugars and artificial sweeteners consumption among cancer patients undergoing radiation therapy: a cross-sectional study
Rationale: Excessive consumption of sugar or its products is linked with the etiology of cancer and its recurrence via obesity, insulin resistance, oxidative pathways, and inflammatory responses.(1)The aim of this study is to assess knowledge, attitude, and practice ( KAP ) regarding natural sugars and artificial sweeteners consumption in cancer radiation therapy patients . (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: V.B. Gorey, M. Nigudkar, A. Doshi Source Type: research
Non-nutritive sweeteners and body weight management: another brick in the wall of evidence
International Journal of Obesity, Published online: 27 November 2023; doi:10.1038/s41366-023-01419-wNon-nutritive sweeteners and body weight management: another brick in the wall of evidence (Source: International Journal of Obesity)
Source: International Journal of Obesity - November 27, 2023 Category: Eating Disorders & Weight Management Authors: Peter J. Rogers Source Type: research
