BETA-CARYOPHYLLENE MITIGATES THE COGNITIVE IMPAIRMENT CAUSED BY REPEATED EXPOSURE TO ASPARTAME IN RATS: PUTATIVE ROLE OF BDNF - TrKB SIGNALING PATHWAY AND ACETYLCHOLINESTERASE ACTIVITY

In conclusion, BCP protected against ASP-induced memory impairment. AChE activity and the BDNF/TrkB signaling pathway seem to be potential targets of BCP modulatory role in this study.PMID:37558167 | DOI:10.1016/j.bbr.2023.114615

Source: Brain Research - August 9, 2023 Category: Neurology Authors: Érica Vanessa Furlan Rosa Alice Rosa DA Silveira Marcel Henrique Marcondes Sari Tuane Bazanella Sampaio Jamila Trindade Dos Santos Sabrina Grendene M üller Michele Rechia Fighera Luiz Fernando Freire Royes Cristina Wayne Nogueira Mauro Schneider Oliveir Source Type: research