Real-World Effectiveness and Safety of Ramucirumab as a Second-Line Treatment for Patients with Unresectable Advanced or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma in Japan and South Korea: A Systematic Literature Review
CONCLUSION: RAM + PTX as a second-line treatment is effective and associated with an acceptable toxicity profile in patients with advanced or metastatic G/GEA in real-world settings of Japan and South Korea. More studies are recommended to further evaluate effectiveness and safety of RAM or RAM-based therapy, especially after anti-PD-1 therapy, in a wider Eastern Asian population.TRIAL REGISTRATION: INPLASY registration number INPLASY2022120023.PMID:38619719 | DOI:10.1007/s12325-024-02838-5 (Source: Adv Data)
Source: Adv Data - April 15, 2024 Category: Epidemiology Authors: Xiaotian Zhang Li Zhou Chan Zhou Lin Shen Source Type: research
Characteristics and outcomes of the drug patent linkage system in China
This study describes the characterist... (Source: Globalization and Health)
Source: Globalization and Health - April 15, 2024 Category: International Medicine & Public Health Authors: Xue-Fang Yao Tags: Research Source Type: research
Real-World Effectiveness and Safety of Ramucirumab as a Second-Line Treatment for Patients with Unresectable Advanced or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma in Japan and South Korea: A Systematic Literature Review
ConclusionRAM + PTX as a second-line treatment is effective and associated with an acceptable toxicity profile in patients with advanced or metastatic G/GEA in real-world settings of Japan and South Korea. More studies are recommended to further evaluate effectiveness and safety of RAM or RAM-based therapy, especially after anti-PD-1 therapy, in a wider Eastern Asian population.Trial RegistrationINPLASY registration number INPLASY2022120023. (Source: Advances in Therapy)
Source: Advances in Therapy - April 15, 2024 Category: Drugs & Pharmacology Source Type: research
Cardiovascular safety of evogliptin dual and triple therapy in patients with type 2 diabetes: a nationwide cohort study
Conclusions
These findings suggest that dual or triple therapies of evogliptin for the management of type 2 diabetes in routine clinical practice present no cardiovascular harms, but could alternatively offer cardiovascular benefits in this patient population. (Source: BMJ Open)
Source: BMJ Open - April 15, 2024 Category: General Medicine Authors: Park, S., Jeong, H. E., Oh, I.-S., Hong, S., Yu, S. H., Lee, C. B., Shin, J.-Y. Tags: Open access, Diabetes and Endocrinology Source Type: research
Cancers, Vol. 16, Pages 1499: Reactivation of Varicella-Zoster Virus in Patients with Lung Cancer Receiving Immune Checkpoint Inhibitors: Retrospective Nationwide Population-Based Cohort Study from South Korea
Conclusions: In these real-world data from an Asian population with lung cancer, ICIs treatment might be associated with a reduced risk of HZ compared to that without ICIs treatment. (Source: Cancers)
Source: Cancers - April 14, 2024 Category: Cancer & Oncology Authors: Jiyun Jung Seong-Yeon Park Jae-Yoon Park Dalyong Kim Kyoungmin Lee Sungim Choi Tags: Article Source Type: research
Long-term exposure to air pollution and precocious puberty in South Korea
CONCLUSIONS: This study provides valuable insights into the harmful effects of air pollution during childhood and adolescence, emphasizing that air pollution is a risk factor that should be managed and reduced.PMID:38614201 | DOI:10.1016/j.envres.2024.118916 (Source: Environmental Research)
Source: Environmental Research - April 13, 2024 Category: Environmental Health Authors: Jongmin Oh Jung Eun Choi Rosie Lee Eunji Mun Kyung Hee Kim Ji Hyen Lee Jungsil Lee Soontae Kim Hae Soon Kim Eunhee Ha Source Type: research
Association between Head and Neck Cancer and Increased Risk of Ischemic Heart Disease: A Retrospective Cohort Study Using National Population Data
Cancers (Basel). 2024 Mar 29;16(7):1352. doi: 10.3390/cancers16071352.ABSTRACTAlthough cancer and ischemic heart disease (IHD) frequently manifest in the same individual, the risk of IHD events in cancer, especially head and neck cancer (HNC), remains unclear. We aimed to examine the incidence and risk of IHD events in patients with HNC using a population-based cohort dataset in South Korea (2002-2013). Through rigorous propensity score matching, we compared data from 2816 individuals without HNC and 704 individuals with HNC. Key independent variables were matched between groups, and the Charlson Comorbidity Index was used...
Source: Cancer Control - April 13, 2024 Category: Cancer & Oncology Authors: Chulho Kim Hyunjae Yu Dong-Kyu Kim Source Type: research
Myotonic dystrophy type 1 in South Korea: a comprehensive analysis of cancer and comorbidity risks
ConclusionsDM1 patients have a noteworthy occurrence of several comorbidities such as cancer, diabetes, thyroid dysfunction, and earlier cataract surgery. This highlights the importance of a comprehensive and integrative approach to the management and treatment of DM1, going beyond addressing only the primary neuromuscular symptoms. More research is required to understand the underlying mechanisms contributing to these comorbidities in DM1 patients, which may inform preventative measures and guide improvements in patient care. (Source: Neurological Sciences)
Source: Neurological Sciences - April 13, 2024 Category: Neurology Source Type: research
Bibliometric analysis of auriculotherapy research trends over the past 20 years
CONCLUSION: Auriculotherapy research primarily focused on clinical studies related to pain, obesity, smoking cessation, and depression. Future research should place greater emphasis on verifying the mechanisms of auriculotherapy for specific ailments and may require efforts to enhance the robustness of clinical trials. Through visual analysis, our study may serve as a foundational resource, offering valuable insights into the trajectory of auriculotherapy research.PMID:38608787 | DOI:10.1016/j.ctim.2024.103036 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - April 12, 2024 Category: Complementary Medicine Authors: Hyonjun Chun Woo-Chul Shin Sungjun Joo Hyungsuk Kim Jae-Heung Cho Mi-Yeon Song Won-Seok Chung Source Type: research
Microbiome Profile of South Korean Vector Mosquitoes
This study sheds light on the complex interactions between mosquitoes and their microbiome, revealing potential implications for vector competence, disease transmission, and vector control strategies.PMID:38608996 | DOI:10.1016/j.actatropica.2024.107213 (Source: Acta Tropica)
Source: Acta Tropica - April 12, 2024 Category: Infectious Diseases Authors: Ashraf Akintayo Akintola Ui Wook Hwang Source Type: research
Microbiome Profile of South Korean Vector Mosquitoes
This study sheds light on the complex interactions between mosquitoes and their microbiome, revealing potential implications for vector competence, disease transmission, and vector control strategies.PMID:38608996 | DOI:10.1016/j.actatropica.2024.107213 (Source: Acta Tropica)
Source: Acta Tropica - April 12, 2024 Category: Infectious Diseases Authors: Ashraf Akintayo Akintola Ui Wook Hwang Source Type: research
Microbiome Profile of South Korean Vector Mosquitoes
This study sheds light on the complex interactions between mosquitoes and their microbiome, revealing potential implications for vector competence, disease transmission, and vector control strategies.PMID:38608996 | DOI:10.1016/j.actatropica.2024.107213 (Source: Acta Tropica)
Source: Acta Tropica - April 12, 2024 Category: Infectious Diseases Authors: Ashraf Akintayo Akintola Ui Wook Hwang Source Type: research
Bibliometric analysis of auriculotherapy research trends over the past 20 years
CONCLUSION: Auriculotherapy research primarily focused on clinical studies related to pain, obesity, smoking cessation, and depression. Future research should place greater emphasis on verifying the mechanisms of auriculotherapy for specific ailments and may require efforts to enhance the robustness of clinical trials. Through visual analysis, our study may serve as a foundational resource, offering valuable insights into the trajectory of auriculotherapy research.PMID:38608787 | DOI:10.1016/j.ctim.2024.103036 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - April 12, 2024 Category: Complementary Medicine Authors: Hyonjun Chun Woo-Chul Shin Sungjun Joo Hyungsuk Kim Jae-Heung Cho Mi-Yeon Song Won-Seok Chung Source Type: research
Virulence Genes, Antimicrobial Resistance, and Genotypes of Campylobacter jejuni Isolated from Chicken Slaughterhouses in South Korea
Foodborne Pathogens and Disease, Ahead of Print. (Source: Foodborne Pathogens and Disease)
Source: Foodborne Pathogens and Disease - April 12, 2024 Category: Food Science Authors: Jiyeon Jeong Ji-Youn Lee Jin-San Moon Min-Su Kang Sung-Il Kang O-Mi Lee So-Hee Lee Yong-Kuk Kwon Myeongju Chae Seongbeom Cho Source Type: research
Impact of statutory revisions to family-petitioned civil commitment in South Korea
CONCLUSION: The findings were based on cross-sectional correlational data and should not be viewed as conclusive evidence that the 2016 statutory revision is ineffective in preventing family-petitioned civil commitment in cases where dangerousness is not apparent. Nevertheless, these findings encourage further empirical studies that illuminate the etiology of procedural justice in civil commitments petitioned by family members and that assess factors and contexts that promote the consideration of least coercive treatments, rather than resorting to involuntary hospitalization when psychiatric emergencies arise.PMID:38603975...
Source: International Journal of Law and Psychiatry - April 11, 2024 Category: Medical Law Authors: Hyunsung Oh Yunhwa Cho Jinyeong Bae Lynn C Holley Michael Shafer Kyejung Kim Yongpyo Lee Source Type: research
