Comparative Analysis of Clinical Outcomes Using Propensity Score Matching: Coronavirus Disease 2019 vs. Seasonal Influenza in Korea
CONCLUSION: The omicron group did not demonstrate better clinical outcomes than the pre-omicron group, and exhibited significant disease severity compared to the influenza group. Considering the likely persistence of COVID-19 infections, it is imperative to sustain comprehensive studies and ongoing policy support for the virus to enhance the prognosis for individuals affected by COVID-19.PMID:38622937 | PMC:PMC11018986 | DOI:10.3346/jkms.2024.39.e128 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 16, 2024 Category: Biomedical Science Authors: Jae Kyeom Sim Hye Sun Lee Juyeon Yang Jin Gwack Bryan Inho Kim Jeong-Ok Cha Kyung Hoon Min Young Seok Lee Severe Acute Respiratory Infection (SARI) Investigators Source Type: research

Comparative Analysis of Clinical Outcomes Using Propensity Score Matching: Coronavirus Disease 2019 vs. Seasonal Influenza in Korea
CONCLUSION: The omicron group did not demonstrate better clinical outcomes than the pre-omicron group, and exhibited significant disease severity compared to the influenza group. Considering the likely persistence of COVID-19 infections, it is imperative to sustain comprehensive studies and ongoing policy support for the virus to enhance the prognosis for individuals affected by COVID-19.PMID:38622937 | PMC:PMC11018986 | DOI:10.3346/jkms.2024.39.e128 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Jae Kyeom Sim Hye Sun Lee Juyeon Yang Jin Gwack Bryan Inho Kim Jeong-Ok Cha Kyung Hoon Min Young Seok Lee Severe Acute Respiratory Infection (SARI) Investigators Source Type: research

Clinical and Genetic Characteristics Associated With Survival Outcome in Late-Onset Huntington's Disease in South Korea
CONCLUSIONS: Survival after disease onset was shorter in patients with LoHD than in those with CoHD. More mutant CAG repeats and higher AAO were associated with shorter survival in patients with HD.PMID:38627228 | DOI:10.3988/jcn.2023.0329 (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 16, 2024 Category: Neurology Authors: Yun Su Hwang Sungyang Jo Gu-Hwan Kim Jee-Young Lee Ho-Sung Ryu Eungseok Oh Seung-Hwan Lee Young Seo Kim Sun Ju Chung Source Type: research

Influenza and the risk of active tuberculosis occurrence among individuals with latent tuberculosis infection: A national cohort study in South Korea (2015-2020)
CONCLUSIONS: In individuals with LTBI not receiving TPT, experiencing an influenza episode may elevate the risk of developing active TB.PMID:38627123 | DOI:10.1016/j.jmii.2024.04.003 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - April 16, 2024 Category: Microbiology Authors: Jaehee Lee Hyewon Seo Dohyang Kim Jinseub Hwang Jin-Won Kwon Source Type: research

Clinical and Genetic Characteristics Associated With Survival Outcome in Late-Onset Huntington's Disease in South Korea
CONCLUSIONS: Survival after disease onset was shorter in patients with LoHD than in those with CoHD. More mutant CAG repeats and higher AAO were associated with shorter survival in patients with HD.PMID:38627228 | DOI:10.3988/jcn.2023.0329 (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 16, 2024 Category: Neurology Authors: Yun Su Hwang Sungyang Jo Gu-Hwan Kim Jee-Young Lee Ho-Sung Ryu Eungseok Oh Seung-Hwan Lee Young Seo Kim Sun Ju Chung Source Type: research

Influenza and the risk of active tuberculosis occurrence among individuals with latent tuberculosis infection: A national cohort study in South Korea (2015-2020)
CONCLUSIONS: In individuals with LTBI not receiving TPT, experiencing an influenza episode may elevate the risk of developing active TB.PMID:38627123 | DOI:10.1016/j.jmii.2024.04.003 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - April 16, 2024 Category: Microbiology Authors: Jaehee Lee Hyewon Seo Dohyang Kim Jinseub Hwang Jin-Won Kwon Source Type: research

Clinical and Genetic Characteristics Associated With Survival Outcome in Late-Onset Huntington's Disease in South Korea
CONCLUSIONS: Survival after disease onset was shorter in patients with LoHD than in those with CoHD. More mutant CAG repeats and higher AAO were associated with shorter survival in patients with HD.PMID:38627228 | DOI:10.3988/jcn.2023.0329 (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 16, 2024 Category: Neurology Authors: Yun Su Hwang Sungyang Jo Gu-Hwan Kim Jee-Young Lee Ho-Sung Ryu Eungseok Oh Seung-Hwan Lee Young Seo Kim Sun Ju Chung Source Type: research

Comparative Analysis of Clinical Outcomes Using Propensity Score Matching: Coronavirus Disease 2019 vs. Seasonal Influenza in Korea
CONCLUSION: The omicron group did not demonstrate better clinical outcomes than the pre-omicron group, and exhibited significant disease severity compared to the influenza group. Considering the likely persistence of COVID-19 infections, it is imperative to sustain comprehensive studies and ongoing policy support for the virus to enhance the prognosis for individuals affected by COVID-19.PMID:38622937 | PMC:PMC11018986 | DOI:10.3346/jkms.2024.39.e128 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 16, 2024 Category: Biomedical Science Authors: Jae Kyeom Sim Hye Sun Lee Juyeon Yang Jin Gwack Bryan Inho Kim Jeong-Ok Cha Kyung Hoon Min Young Seok Lee Severe Acute Respiratory Infection (SARI) Investigators Source Type: research

Clinical and Genetic Characteristics Associated With Survival Outcome in Late-Onset Huntington's Disease in South Korea
CONCLUSIONS: Survival after disease onset was shorter in patients with LoHD than in those with CoHD. More mutant CAG repeats and higher AAO were associated with shorter survival in patients with HD.PMID:38627228 | DOI:10.3988/jcn.2023.0329 (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 16, 2024 Category: Neurology Authors: Yun Su Hwang Sungyang Jo Gu-Hwan Kim Jee-Young Lee Ho-Sung Ryu Eungseok Oh Seung-Hwan Lee Young Seo Kim Sun Ju Chung Source Type: research

Rimegepant orally disintegrating tablet 75  mg for acute treatment of migraine in adults from China: a subgroup analysis of a double-blind, randomized, placebo-controlled, phase 3 clinical trial
ConclusionsA single dose of rimegepant 75  mg rimegepant was effective for the acute treatment of migraine in adults living in China, with safety and tolerability similar to placebo.Trial registration Clinicaltrials.gov NCT04574362  Date registered: 2020-10-05.Graphical Abstract (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - April 16, 2024 Category: Neurology Source Type: research

Real-World Effectiveness and Safety of Ramucirumab as a Second-Line Treatment for Patients with Unresectable Advanced or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma in Japan and South Korea: A Systematic Literature Review
CONCLUSION: RAM + PTX as a second-line treatment is effective and associated with an acceptable toxicity profile in patients with advanced or metastatic G/GEA in real-world settings of Japan and South Korea. More studies are recommended to further evaluate effectiveness and safety of RAM or RAM-based therapy, especially after anti-PD-1 therapy, in a wider Eastern Asian population.TRIAL REGISTRATION: INPLASY registration number INPLASY2022120023.PMID:38619719 | DOI:10.1007/s12325-024-02838-5 (Source: Adv Data)
Source: Adv Data - April 15, 2024 Category: Epidemiology Authors: Xiaotian Zhang Li Zhou Chan Zhou Lin Shen Source Type: research

Real-World Effectiveness and Safety of Ramucirumab as a Second-Line Treatment for Patients with Unresectable Advanced or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma in Japan and South Korea: A Systematic Literature Review
CONCLUSION: RAM + PTX as a second-line treatment is effective and associated with an acceptable toxicity profile in patients with advanced or metastatic G/GEA in real-world settings of Japan and South Korea. More studies are recommended to further evaluate effectiveness and safety of RAM or RAM-based therapy, especially after anti-PD-1 therapy, in a wider Eastern Asian population.TRIAL REGISTRATION: INPLASY registration number INPLASY2022120023.PMID:38619719 | DOI:10.1007/s12325-024-02838-5 (Source: Adv Data)
Source: Adv Data - April 15, 2024 Category: Epidemiology Authors: Xiaotian Zhang Li Zhou Chan Zhou Lin Shen Source Type: research