Aesthetic doctors' perception and attitudes toward tolerance in botulinum toxin
CONCLUSION: In the South Korean aesthetic medicine community, a majority of clinical physician's report encountering botulinum toxin resistance. Given the potential loss of various benefits associated with resistance, there is a need to establish appropriate guidelines based on mechanistic studies and current status assessments. Educating clinicians on applicable guidelines is crucial.PMID:38576226 | DOI:10.1111/srt.13691 (Source: Cell Research)
Source: Cell Research - April 5, 2024 Category: Cytology Authors: Seung Min Oh Hyoung Moon Kim Tae Hwan Ahn Min Soo Park Yoo-Seock Ree Eun Soo Park Source Type: research

Recent trends in the epidemiology and clinical outcomes of inflammatory bowel disease in South Korea, 2010-2018
CONCLUSION: The CD incidence has been stable since 2014, but that of UC has increased with a shift to a younger age at peak incidence between 2010 and 2018. IBD clinical outcomes improved over time, with increased use of immunomodulators and biologics.PMID:38577186 | PMC:PMC10989502 | DOI:10.3748/wjg.v30.i9.1154 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 5, 2024 Category: Gastroenterology Authors: Seulji Kim Hyun Jung Lee Seung Woo Lee Sanghyun Park Seong-Joon Koh Jong Pil Im Byeong Gwan Kim Kyung-Do Han Joo Sung Kim Source Type: research

Factors Associated With Achieving Complete Skin Clearance Compared to Almost Complete Skin Clearance in Patients With Moderate to Severe Psoriasis Treated With Biologics: A Retrospective Chart Review
CONCLUSION: This study suggested that smoking history and psoriatic skin lesions on the anterior lower legs are considered as the risk factors for the failure to achieve a PASI100 response in psoriasis patients treated with biologics.PMID:38576247 | PMC:PMC10995612 | DOI:10.5021/ad.23.074 (Source: Annals of Dermatology)
Source: Annals of Dermatology - April 5, 2024 Category: Dermatology Authors: Eun Ji Hong Hee Jung Yoon Min Jung Kwon Jae Yun Kim Jung Eun Kim Young Lip Park SangHoon Lee Youin Bae Sul Hee Lee Source Type: research

Recent trends in the epidemiology and clinical outcomes of inflammatory bowel disease in South Korea, 2010-2018
CONCLUSION: The CD incidence has been stable since 2014, but that of UC has increased with a shift to a younger age at peak incidence between 2010 and 2018. IBD clinical outcomes improved over time, with increased use of immunomodulators and biologics.PMID:38577186 | PMC:PMC10989502 | DOI:10.3748/wjg.v30.i9.1154 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Authors: Seulji Kim Hyun Jung Lee Seung Woo Lee Sanghyun Park Seong-Joon Koh Jong Pil Im Byeong Gwan Kim Kyung-Do Han Joo Sung Kim Source Type: research

Factors Associated With Achieving Complete Skin Clearance Compared to Almost Complete Skin Clearance in Patients With Moderate to Severe Psoriasis Treated With Biologics: A Retrospective Chart Review
CONCLUSION: This study suggested that smoking history and psoriatic skin lesions on the anterior lower legs are considered as the risk factors for the failure to achieve a PASI100 response in psoriasis patients treated with biologics.PMID:38576247 | PMC:PMC10995612 | DOI:10.5021/ad.23.074 (Source: Annals of Dermatology)
Source: Annals of Dermatology - April 5, 2024 Category: Dermatology Authors: Eun Ji Hong Hee Jung Yoon Min Jung Kwon Jae Yun Kim Jung Eun Kim Young Lip Park SangHoon Lee Youin Bae Sul Hee Lee Source Type: research

Secondary hematological malignancies in patients with sarcoma: A single ‑center retrospective study
Oncol Lett. 2024 Mar 14;27(5):211. doi: 10.3892/ol.2024.14344. eCollection 2024 May.ABSTRACTThe present retrospective study investigated the clinical features and prognosis of secondary hematological malignancies (SHMs) in patients with sarcoma at Korea Cancer Center Hospital (Seoul, South Korea). Patients who had been diagnosed with SHMs after having received treatment for sarcoma between January 2000 and May 2023 were enrolled. Clinical data were collected from the patients' medical records. Clinical characteristics were analyzed, including SHM incidence, type and prognosis. Of 2,953 patients with sarcoma, 18 (0.6%) were...
Source: Oncology Letters - April 4, 2024 Category: Cancer & Oncology Authors: Yoon Jung Jang Hong Kyu Jeong Chang-Bae Kong Won Seok Song Wan Hyeong Cho Dae Geun Jeon Heyjin Kim Sung Hyun Yang Im Il Na Hyo-Rak Lee Hye Jin Kang Source Type: research

Maximizing the Value of Real-World Data and Real-World Evidence to Accelerate Healthcare Transformation in China: Summary of External Advisory Committee Meetings
AbstractUse of real-world data (RWD) is gaining wide attention. To bridge the gap between diverse healthcare stakeholders and to leverage the impact of Chinese real-world evidence (RWE) globally, a multi-stakeholder External Advisory Committee (EAC) and EAC meetings were initiated, aiming to elucidate the current and evolving RWD landscape in China, articulate the values of RWE in ensuring Chinese patients ’ equitable access to affordable medicines and solutions, and identify strategic opportunities and partnerships for expansion of RWE generation in China. Chinese and international experts who are clinicians and academi...
Source: Pharmaceutical Medicine - April 4, 2024 Category: Drugs & Pharmacology Source Type: research

Evaluation of vaccine effectiveness of mRNA COVID-19 vaccines in children: a systematic review and meta-analysis
CONCLUSIONS: Both partial and full immunization of the BNT162b2 mRNA vaccine provide benefits in reducing infection rates. VE varies over time and is closely associated with viral mutations and waning immunity. The specific mechanisms require further investigation.PMID:38567617 | DOI:10.26355/eurrev_202403_35764 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: Y-H Hu Y Ding L-W Li J Cheng Y-H Cai Source Type: research

Evaluation of vaccine effectiveness of mRNA COVID-19 vaccines in children: a systematic review and meta-analysis
CONCLUSIONS: Both partial and full immunization of the BNT162b2 mRNA vaccine provide benefits in reducing infection rates. VE varies over time and is closely associated with viral mutations and waning immunity. The specific mechanisms require further investigation.PMID:38567617 | DOI:10.26355/eurrev_202403_35764 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: Y-H Hu Y Ding L-W Li J Cheng Y-H Cai Source Type: research

Evaluation of vaccine effectiveness of mRNA COVID-19 vaccines in children: a systematic review and meta-analysis
CONCLUSIONS: Both partial and full immunization of the BNT162b2 mRNA vaccine provide benefits in reducing infection rates. VE varies over time and is closely associated with viral mutations and waning immunity. The specific mechanisms require further investigation.PMID:38567617 | DOI:10.26355/eurrev_202403_35764 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: Y-H Hu Y Ding L-W Li J Cheng Y-H Cai Source Type: research