Palliative Care in Sickle Cell Disease: Development of an International Working Group
1. Upon successful completion, participants will be able to understand the history of palliative care (PC) in sickle cell disease (SCD) and primary impetus for development of an international PC in SCD Working Group.2. Upon successful completion, participants will be able to identify the demographic makeup, top priorities and planned deliverables defined by the members of the International Palliative Care in Sickle Cell Disease Working Group. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Ashley Allen, Stephanie B. Kiser, Eberechi Nwogu-Onyemkpa Source Type: research
A Multidisciplinary Approach to Managing an Acute Sickle Cell Exacerbation
1. Recognize patient-related factors in patients with sickle cell disease that would benefit from a multidisciplinary palliative care approach.2. Describe palliative care interventions that may positively impact total pain in a hospitalized patient with sickle cell disease. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Joshua Borris, Paul Noufi Source Type: research
Equity in Palliative Care: Interviews with Leaders of a Sickle Cell Community-Facing Organization
1. Utilizing a narrative-based approach, participants will learn the motivations for creating a culturally-competent, far-reaching community-based organization for an underserved chronic disease (SCD) and apply this knowledge toward better integration of PC.2. Utilizing DEIJB principles, participants will analyze community leader responses to a series of interview questions regarding attitudes/perceptions toward PC and lay the groundwork for an innovative social media-directed collaboration to introduce PC to to the SCD community at-large. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Mgbechi U. Erondu, Stephen Boateng Source Type: research
Sickle Cell Disease: A Primer for the Palliative Care Clinician
1. Participants will be able to understand the pathophysiology of sickle cell disease including complications of the disease and its impact on quality of life within physical, psychological, social, racial and emotional domains.2. Participants will be able to define the palliative care needs of patients with sickle cell disease and communicate the role of palliative care in improving the quality of life in this patient population. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Ashley Allen, Stephanie B. Kiser, Eberechi Nwogu-Onyemkpa Source Type: research
Sickle Cell Disease Providers' Perspectives on Palliative Care
1. Identify facilitators and barriers to palliative care referrals by sickle cell disease providers.2. Utilizing results from the studies, participants will identify strategies to increase collaboration between palliative care and sickle cell disease providers. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Eberechi Nwogu-Onyemkpa, Nimrah Saleem, Amber Amspoker Source Type: research
The Opportunities and Challenges of Establishing Palliative Care in Sickle Cell Disease: What's Our Role?
1. Identify the unique challenges and opportunities in defining the role of palliative care for patients with sickle cell disease.2. Describe novel models of palliative care practice for patients with sickle cell disease. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Stephanie Kiser, Eberechi Nwogu-Onyemkpa, Ashley Allen, Toluwalase A. Ajayi, Craig D. Blinderman, Rushil V. Patel, Ava R. Farrell Source Type: research
Persistent Pain Below the Belt: Palliative Care's Unusual Role in the Management of Priapism
1. Participants will hypothesize and discuss the potential elements of total pain experienced by sickle cell patients facing complications of prolonged priapism, including but not limited to: physical, social, spiritual, cultural, existential, and psychological aspects of pain.2. Participants will recognize and analyze the diverse implications associated with the complications of prolonged priapism, specifically exploring the impact on the patient's mental, sexual, and reproductive health. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Lauren Lewis, Ashima Lal, Carina Oltmann Source Type: research
A Systemic Review of the Psychosocial Aspects of Chronic Pain in Youth With Sickle Cell Disease
The psychosocial aspects of chronic pain among youth with sickle cell are poorly described and may be better understood within a biopsychosocial model of chronic pain as applied to youth living with sickle cell disease. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 19, 2024 Category: Nursing Authors: Megan Coco, Angela R. Starkweather, Crystal L. Park, Wendy Henderson Tags: Review Article Source Type: research
Genetic Variants Associated with the Risk of Stroke in Sickle Cell Anemia: Systematic Review and Meta-Analysis
. (Source: Hemoglobin)
Source: Hemoglobin - April 19, 2024 Category: Hematology Authors: Aradhana KumariGanesh ChauhanPartha Kumar ChaudhuriSushma KumariAnupa Prasada Department of Genetics and Genomics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, Indiab Department of Biochemistry, Rajendra Institute of Medical Sciences, Ranchi Source Type: research
Beyond adenosine triphosphate: unveiling the pleiotropic effects of pyruvate kinase activation in sickle cell anemia
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285390. Online ahead of print.ABSTRACTNot available.PMID:38634127 | DOI:10.3324/haematol.2024.285390 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Andreas Glenth øj Source Type: research
Beyond adenosine triphosphate: unveiling the pleiotropic effects of pyruvate kinase activation in sickle cell anemia
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285390. Online ahead of print.ABSTRACTNot available.PMID:38634127 | DOI:10.3324/haematol.2024.285390 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Andreas Glenth øj Source Type: research
Estimating the serological underrecognition of patients with weak or partial RHD variants
DISCUSSION: Based on AF, >80% of patients with weak or partial RHD variants were unrecognized serologically. Although overall anti-D rates were low, better detection of partial RHD variants is desirable.PMID:38634174 | DOI:10.1111/trf.17810 (Source: Transfusion)
Source: Transfusion - April 18, 2024 Category: Hematology Authors: Glenn Ramsey Christina M Barriteau Source Type: research
Beyond adenosine triphosphate: unveiling the pleiotropic effects of pyruvate kinase activation in sickle cell anemia
Haematologica. 2024 Apr 18. doi: 10.3324/haematol.2024.285390. Online ahead of print.ABSTRACTNot available.PMID:38634127 | DOI:10.3324/haematol.2024.285390 (Source: Haematologica)
Source: Haematologica - April 18, 2024 Category: Hematology Authors: Andreas Glenth øj Source Type: research
Estimating the serological underrecognition of patients with weak or partial RHD variants
DISCUSSION: Based on AF, >80% of patients with weak or partial RHD variants were unrecognized serologically. Although overall anti-D rates were low, better detection of partial RHD variants is desirable.PMID:38634174 | DOI:10.1111/trf.17810 (Source: Transfusion)
Source: Transfusion - April 18, 2024 Category: Hematology Authors: Glenn Ramsey Christina M Barriteau Source Type: research
Decreased risk of underdosing with continuous infusion versus intermittent administration of cefotaxime in patients with sickle cell disease and acute chest syndrome
by Keyvan Razazi, Enora Berti, Jerome Cecchini, Guillaume Carteaux, Anoosha Habibi, Pablo Bartolucci, Romain Arrestier, S égolène Gendreau, Nicolas de Prost, Anne Hulin, Armand Mekontso Dessap
ObjectiveUnderdosing of antibiotics is common in patients with sickle cell disease (SCD). We hypothesized that in critically-ill patients with SCD receiving cefotaxime during acute chest syndrome, the continuous infusion may outperform the intermittent administration in achieving pharmacokinetic/pharmacodynamic targets. DesignProspective before-after study. SettingsIntensive-care unit of a French teaching hospital and sickle cell d...
Source: PLoS One - April 18, 2024 Category: Biomedical Science Authors: Keyvan Razazi Source Type: research
