Rethinking rideshares: a transportation assistance pilot for pediatric patients with sickle cell disease - Vais S, Thomson L, Williams A, Sobota A.
This study assesses the efficacy of heal... (Source: SafetyLit)
Source: SafetyLit - January 11, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

mRNA Technology Gave Us the First COVID-19 Vaccines. It Could Also Upend the Drug Industry
“No!” The doctor snapped. “Look at me!” I had been staring her in the eyes, as she had ordered, but when a doctor on my other side began jabbing me with a needle, I started to turn my head. “Don’t look at it,” the first doctor said. I obeyed. This was in early August in New Orleans, where I had signed up to be a participant in the clinical trial for the Pfizer-BioNTech COVID-19 vaccine. It was a blind study, which meant I was not supposed to know whether I had gotten the placebo or the real vaccine. I asked the doctor if I would really been able to tell by looking at the syringe. &...
Source: TIME: Health - January 11, 2021 Category: Consumer Health News Authors: Walter Isaacson Tags: Uncategorized COVID-19 feature Magazine Source Type: news

mRNA Technology Gave Us the First COVID-19 Vaccines. It Could Also Upend the Drug Industry
“No!” The doctor snapped. “Look at me!” I had been staring her in the eyes, as she had ordered, but when a doctor on my other side began jabbing me with a needle, I started to turn my head. “Don’t look at it,” the first doctor said. I obeyed. This was in early August in New Orleans, where I had signed up to be a participant in the clinical trial for the Pfizer-BioNTech COVID-19 vaccine. It was a blind study, which meant I was not supposed to know whether I had gotten the placebo or the real vaccine. I asked the doctor if I would really been able to tell by looking at the syringe. &...
Source: TIME: Science - January 11, 2021 Category: Science Authors: Walter Isaacson Tags: Uncategorized COVID-19 feature Magazine Source Type: news

Sickle-Cell Trait May Not Independently Elevate CHD Risk Sickle-Cell Trait May Not Independently Elevate CHD Risk
Coronary heart disease didn't seem to explain the risk of sudden death associated with the trait in a combined analysis of five major population-based studies.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 9, 2021 Category: Cancer & Oncology Tags: Cardiology News Source Type: news

Study: Sickle cell trait does not increase heart disease risk in African Americans
Carrying the sickle cell trait does not play a significant role in the increased risk for coronary heart disease among African Americans, a study published Tuesday by JAMA Network Open found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - January 5, 2021 Category: Consumer Health News Source Type: news

Updated advice on COVID-19 vaccination in pregnancy and women who are breastfeeding, RCOG
The Government has today accepted the recommendation from the Medicines and Healthcare products Regulatory Agency (MHRA) to authorise Oxford University/AstraZeneca's COVID-19 vaccine for use. The Joint Committee on Vaccination and Immunisation (JCVI) has also published its latest advice for the priority groups to receive the Oxford University/AstraZeneca and the Pfizer/BioNTech vaccines. This includes updated advice for pregnant and breastfeeding women who meet other criteria for priority vaccination. The JCVI confirms that although the available data do not indicate any safety concern or harm to pregnancy, there is insuf...
Source: Current Awareness Service for Health (CASH) - December 31, 2020 Category: Consumer Health News Source Type: news

Sickle Cell Puts Black Patients at Higher Risk for Severe COVID
TUESDAY, Dec. 15, 2020 -- Sickle cell disease increases the risk of death or serious complications from COVID-19 infection, a pair of new studies suggests. People with sickle cell disease -- a genetic blood disorder predominantly found in Black... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 15, 2020 Category: General Medicine Source Type: news

Uganda: Sickle Cell Warriors Receive Phones With Health App for Quick Treatment During Tough Covid-19 Times
[Monitor] At least 10,000 people living with sickle cell anemia, are each to be availed with a smart phone that they can make use of to get treatment from a doctor given the ongoing restrictions caused by Covid-19. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 15, 2020 Category: African Health Source Type: news

Sickle Cell Puts Black Patients at Higher Risk for Severe COVID
Title: Sickle Cell Puts Black Patients at Higher Risk for Severe COVIDCategory: Health NewsCreated: 12/15/2020 12:00:00 AMLast Editorial Review: 12/15/2020 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - December 15, 2020 Category: Anesthesiology Source Type: news

Could Gene Therapy Cure Sickle Cell Disease? Two New Studies Raise Hopes
Title: Could Gene Therapy Cure Sickle Cell Disease? Two New Studies Raise HopesCategory: Health NewsCreated: 12/5/2020 12:00:00 AMLast Editorial Review: 12/7/2020 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - December 7, 2020 Category: Anesthesiology Source Type: news

Gene-editing treatment shows promise for sickle cell disease
Scientists are seeing promising early results from the first studies testing gene editing for painful, inherited blood disorders that plague millions worldwide, especially Black people (Source: ABC News: Health)
Source: ABC News: Health - December 5, 2020 Category: Consumer Health News Tags: Health Source Type: news

Could Gene Therapy Cure Sickle Cell Disease? Two New Studies Raise Hopes
SATURDAY, Dec. 5, 2020 -- A pair of new gene therapies promise a potentially lasting cure for sickle cell disease by subtly altering the genetic information in patients'bone marrow cells, researchers report. Both therapies work by switching on a... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 5, 2020 Category: General Medicine Source Type: news

Integrated anemia-SCD test demonstrates accurate results in study at 2020 ASH meeting
(Whitecoat Strategies, LLC) Researchers from Case Western Reserve University presented research today in which Hemex Health's affordable Gazelle platform diagnostic technology successfully tested 46 patients with 100% sensitivity and over 92.3% specificity for anemia and with 100% accuracy for hemoglobin variants. The preliminary study included blood samples collected from Cleveland-area patients studied for anemia and sickle cell disease. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 5, 2020 Category: Infectious Diseases Source Type: news

UCLA receives $7.3 million grant to build state-of-the-art facility for developing gene, cell therapies
UCLA has received a $7.3 million grant from the National Institutes of Health to build a state-of-the-art facility in which to produce gene and cell therapies aimed at treating a host of illnesses and conditions.The new 13,000-square-foot facility, to be constructed in UCLA ’s Center for the Health Sciences, will provide a highly regulated environment with features such as systems to manage air flow and filtering, laboratory spaces and bioreactors. The new facility is expected to be ready for use in 2023.“This grant provides critical funds to build a facility that will enable the development of a new generation...
Source: UCLA Newsroom: Health Sciences - December 4, 2020 Category: Universities & Medical Training Source Type: news

Gene therapy gives man with sickle cell disease the chance for a better future
For Evie Junior, living with sickle cell disease has been like running a marathon.“But it’s a marathon where as you keep going, the trail gets rockier and then you lose your shoes,” the 27-year-old said. “It gets harder as you get older. Things start to fail and all you can think about is how much worse it’s going to get down the road.”In sickle cell disease, a genetic mutation causes the blood-forming stem cells — which give rise to all blood and immune cells — to produce hard, sickle-shaped red blood cells. These misshapen cells die early, leaving an insufficient numbe...
Source: UCLA Newsroom: Health Sciences - November 30, 2020 Category: Universities & Medical Training Source Type: news

Gene therapy gives man with sickle cell disease the chance for a better future
(University of California - Los Angeles Health Sciences) Watch a video about Evie's treatment with an experimental gene therapy for sickle cell disease here: https://www.youtube.com/watch?v=XmQJpuLx07Y (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 30, 2020 Category: International Medicine & Public Health Source Type: news

Column: For a man long afflicted with an illness made riskier by COVID-19, hope for the holidays
Black people are the overwhelming victims of sickle cell anemia. An experimental gene therapy being tested on Evie Junior, 27, gives him reason to feel positive. (Source: L.A. Times - Health)
Source: L.A. Times - Health - November 29, 2020 Category: Consumer Health News Authors: Sandy Banks Source Type: news

Column: For a man long afflicted with an illness made riskier by COVID-19, hope for the holidays
Black people are the overwhelming victims of sickle cell anemia. An experimental gene therapy being tested on Evie Junior, 27, gives him reason to feel positive. (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - November 29, 2020 Category: Science Authors: Sandy Banks Source Type: news

Researchers tackle sickle cell disease with CRISPR-based gene editing
(ChristianaCare) Scientists at ChristianaCare's Gene Editing Institute have received a $1 million grant from the Lisa Dean Moseley Foundation to develop a novel gene therapy for inherited blood disorders including sickle cell disease, offering hope to nearly 100,000 Americans suffering from the disease who are disproportionately African American. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 23, 2020 Category: International Medicine & Public Health Source Type: news

Assay for Sickle Cell Anemia Is Repurposed to Diagnose COVID-19
A CRISPR-based, paper-strip test developed by Indian researchers performs as well as real-time PCR in identifying the presence of SARS-CoV-2 and returns results within an hour. (Source: The Scientist)
Source: The Scientist - November 18, 2020 Category: Science Tags: News & Opinion Source Type: news

Africa: Consortium On Newborn Screening in Africa Launch, Promote Care of SCD Patients
[This Day] Each year, an estimated 150,000 babies in Nigeria are born with sickle cell disease (SCD). Yet many do not live past the age of five because they lack access to diagnostic testing and comprehensive care. (Source: AllAfrica News: Pregnancy and Childbirth)
Source: AllAfrica News: Pregnancy and Childbirth - November 5, 2020 Category: OBGYN Source Type: news

FDA Approves Updated Label for Endari(R)
TORRANCE, Calif., Nov. 3, 2020 -- (Healthcare Sales & Marketing Network) -- Emmaus Life Sciences, Inc. (OTC: EMMA), a leader in sickle cell disease treatment, announced today revised prescribing information for Endari® to better inform healthcare prof... Biopharmaceuticals, FDA Emmaus Life Sciences, Endari, L-glutamine, sickle cell (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 3, 2020 Category: Pharmaceuticals Source Type: news

Challenges Of Developing And Facilitating Access To New Sickle Cell Disease Therapies: Case Of The Deferoxamine Patch
Black Americans who suffer from sickle cell disease face resource constraints and unique challenges associated with SCD, which include logistical hurdles such as transportation and insurance coverage. It's important to design equitable access pathways to treatments like the novel deferoxamine patch. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - October 15, 2020 Category: Pharmaceuticals Authors: Joshua Cohen, Contributor Tags: Healthcare /healthcare Innovation /innovation business pharma & Source Type: news

New technology diagnoses sickle cell disease in record time
(University of Colorado at Boulder) Researchers have developed a new way to diagnose diseases of the blood like sickle cell disease with sensitivity and precision and in only one minute. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 15, 2020 Category: International Medicine & Public Health Source Type: news

Coronavirus Disease Among Persons With Sickle Cell Disease Coronavirus Disease Among Persons With Sickle Cell Disease
What have we learned about the severity of COVID-19 among individuals with sickle cell disease?Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 14, 2020 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

Belz Foundation donates $2M to Methodist Le Bonheur ’s Comprehensive Sickle Cell Center
“This gift is the largest we have received this year and is especially impactful during this unprecedented pandemic." (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - October 13, 2020 Category: Health Management Authors: Jason Bolton Source Type: news

$7.1M grant to review opioid alternatives to treating sickle cell disease pain
(University of Illinois at Chicago) Researchers at the University of Illinois Chicago will lead a $7.1 million, five-year national study to determine the effectiveness of acupuncture and guided relaxation for people with chronic pain from sickle cell disease. The National Institutes of Health grant is part of its Helping to End Addiction Long-term Initiative. The initiative aims to improve prevention and treatment strategies for opioid misuse and addiction and to enhance pain management. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 6, 2020 Category: International Medicine & Public Health Source Type: news

Nigeria: 'Advances in Infertility Treatment Prevent Sickle Cell, Other Diseases'
[Daily Trust] Dr Ibrahim Wada is a chief consultant gynaecologist and renowned fertility expert. He is one of the pioneers of IVF breakthroughs in the country and led the birth of Baby Hannatu in 1998. Wada, who is also the founder of Nisa Premier Hospital and chairman of Garki Hospital, Abuja in this interview speaks on advances in infertility care in the country. (Source: AllAfrica News: Pregnancy and Childbirth)
Source: AllAfrica News: Pregnancy and Childbirth - September 29, 2020 Category: OBGYN Source Type: news

Uganda: Sickle Cell Disease Patients to Be Registered
[Monitor] Stakeholders in the fight against Sickle Cell Disease have launched a campaign to raise funds for the establishment of a digital registry of all persons living with Sickle Cell Disease. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 27, 2020 Category: African Health Source Type: news

C-Path launches consortium to support medical product development in sickle cell disease
(Critical Path Institute (C-Path)) C-Path) today announced the launch of the Critical Path for Sickle Cell Disease (CP-SCD) Consortium to support collaboration and regulatory endorsement of new medical product development tools for sickle cell disease. These tools will help to optimize and de-risk clinical trials to increase efficiency in developing and delivering safe, effective treatments for people living with sickle cell disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 17, 2020 Category: International Medicine & Public Health Source Type: news

How this Stanford biotech spinout plans to quickly boost gene therapy
The Peninsula startup snared a $45 million Series A round but plans to start a clinical trial in sickle cell disease as early as the first half of next year. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 16, 2020 Category: Biotechnology Authors: Ron Leuty Source Type: news

How this Stanford biotech spinout plans to quickly boost gene therapy
The Peninsula startup snared a $45 million Series A round but plans to start a clinical trial in sickle cell disease as early as the first half of next year. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - September 16, 2020 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

Nigeria: Hypertension, Cancer, HIV Kill 600,000 Nigerians Annually - NCD Alliance
[Vanguard] Worried about the growing trend of hypertension, cancer, HIV, Sickle Cell Disease, and other Non-Communicable Diseases, NCDs, among Nigerians, President of the NCD Alliance Nigeria, Dr. Sonny Kuku, says not less than 60,000 Nigerians die from these diseases annually. (Source: AllAfrica News: HIV-Aids and STDs)
Source: AllAfrica News: HIV-Aids and STDs - September 11, 2020 Category: Infectious Diseases Source Type: news

Improving Health Outcomes for Sickle Cell Disease Care Requires Comprehensive Team-Based Care, New Payment Models, and Addressing Institutional Racism in Health
A new report from the National Academies of Sciences, Engineering, and Medicine provides a blueprint and eight overarching strategies for improving health care for the approximately 100,000 people in the United States living with sickle cell disease (SCD). (Source: News from the National Academies)
Source: News from the National Academies - September 10, 2020 Category: Science Source Type: news

Medical Marijuana Tied to Fewer Admissions in Sickle Cell Disease
But no change in opioid use observed for those receiving medical marijuana certification (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - September 8, 2020 Category: Cancer & Oncology Tags: Family Medicine, Internal Medicine, Oncology, Pharmacy, Anesthesiology & amp; Pain, Journal, Source Type: news

Medical Marijuana Tied to Fewer Admissions in Sickle Cell Disease
TUESDAY, Sept. 8, 2020 -- Use of medical marijuana is associated with fewer hospitalizations among patients with sickle cell disease (SCD), according to a study published online Aug. 13 in Blood Advances. Susanna A. Curtis, M.D., from the Yale... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 8, 2020 Category: Pharmaceuticals Source Type: news

September 2020
Battling Bent Blood Cells : Progress in Sickle Cell Disease A Biting Problem : Taming TMJ Troubles Dr. Allison King on Sickle Cell Disease and Learning Communicating Clearly While Wearing a Face Covering Protein May Reverse Age-Related Memory Loss Know the Science (Source: NIH News in Health)
Source: NIH News in Health - September 3, 2020 Category: Consumer Health News Source Type: news

South Africa: UCT Professor's Research Offers Hope of Treatment for Sickle Cell Anaemia
[GroundUp] In a study performed in Cameroon, UCT professor Ambroise Wonkam has identified genetic factors which protect some patients from the effects of sickle cell anemia. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 2, 2020 Category: African Health Source Type: news

UTHSC's Athena Starlard-Davenport awarded NIH grant to study potential sickle cell treatment pathway
UTHSC's Athena Starlard-Davenport, Ph.D. — a junior researcher who is "a woman, a scientist, and an African-American woman scientist at that [which] is very rare" — has been awarded an NIH grant to study a potential sickle cell treatment pathway. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - August 26, 2020 Category: Biotechnology Authors: Jason Bolton Source Type: news

Africa: UCT Sickle Cell Genetics Study a First for Africa
[UCT] New research investigating the genetic modifiers of long-term survival in individuals with sickle cell anaemia (SCA) reveals a range of possible pathways for novel therapeutic interventions. Professor Ambroise Wonkam, principle investigator and director of Genetic Medicine of African Populations (GeneMAP) in the University of Cape Town's (UCT) Division of Human Genetics, says apart from the study's clinical potential, the fact that it is so deeply rooted in Africa also presents the opportunity for a paradi (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 25, 2020 Category: African Health Source Type: news

Adding Sickle Cell Disease To FDA ’s Priority Review Voucher List Of Neglected Tropical Diseases
Sickle cell disease lags behind other neglected diseases in terms of R&D. Adding sickle cell disease to the FDA ’s priority review voucher list of neglected tropical diseases may incentivize drug companies to increase their investment in R&D. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - August 18, 2020 Category: Pharmaceuticals Authors: Joshua Cohen, Contributor Tags: Healthcare /healthcare Innovation /innovation business pharma & Source Type: news

Psychosocial and clinical risk factors associated with substance use in observational cohort of patients with sickle cell disease - Wilson JD, Lanzkron S, Pecker LH, Bediako SM, Han D, Beach MC.
BACKGROUND: Patients with sickle cell disease (SCD) experience high rates of chronic pain, and have a high burden of mental health comorbidities shown to negatively influence health. There is limited research on substance use among individuals with SCD. ... (Source: SafetyLit)
Source: SafetyLit - August 14, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Heel-prick blood test could predict type 1 diabetes in children
Heel-prick tests are already used in Britain to check for nine rare but serious conditions, including cystic fibrosis and sickle cell disease. Scientists are pushing for diabetes to be added. (Source: the Mail online | Health)
Source: the Mail online | Health - August 10, 2020 Category: Consumer Health News Source Type: news

Gut Microbiome Translates Stress Into Sickle Cell Crises
July 30, 2020—(BRONX, NY)—A new study shows how chronic psychological stress leads to painful vessel-clogging episodes—the most common complication of sickle-cell disease (SCD) and a frequent cause of hospitalizations. The findings, made in mice, show that the gut microbiome plays a key role in triggering those episodes and reveals possible ways to prevent them. The research was conducted by scientists atAlbert Einstein College of Medicine and published online today inImmunity. (Source: Einstein News)
Source: Einstein News - July 30, 2020 Category: Universities & Medical Training Source Type: news

Gut microbiome translates stress into sickle cell crises
(Albert Einstein College of Medicine) A new study shows how chronic psychological stress leads to painful vessel-clogging episodes--the most common complication of sickle-cell disease (SCD) and a frequent cause of hospitalizations. The findings, made in mice, show that the gut microbiome plays a key role in triggering those episodes and reveals possible ways to prevent them. The research was conducted by scientists at Albert Einstein College of Medicine and published online today in Immunity. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 30, 2020 Category: International Medicine & Public Health Source Type: news

Vaporized cannabis may reduce sickle cell disease pain, study finds
Inhaled cannabis did not significantly reduce pain in hospitalized patients with sickle cell disease who also were treated with prescription opioid pain relievers, a study published Friday by JAMA Network Open found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 17, 2020 Category: Consumer Health News Source Type: news

Cannabis shows potential for mitigating sickle cell disease pain
(University of California - Irvine) Cannabis appears to be a safe and potentially effective treatment for the chronic pain that afflicts people with sickle cell disease, according to a new clinical trial co-led by University of California, Irvine researcher Kalpna Gupta and Dr. Donald Abrams of UC San Francisco. The findings appear in JAMA Network Open. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 17, 2020 Category: International Medicine & Public Health Source Type: news

Umbilical cord blood successfully treats rare genetic disorders in largest study to date
(University of Pittsburgh) Infusing umbilical cord blood - a readily available source of stem cells - safely and effectively treated 44 children born with various non-cancerous genetic disorders, including sickle cell, thalassemia, Hunter syndrome, Krabbe disease, MLD, and an array of immune deficiencies. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 14, 2020 Category: International Medicine & Public Health Source Type: news

Sickle Cell & COVID: What You Need to Know
COVID-19 can cause severe inflammation and lung injury. And that can have a greater impact on people with sickle cell disease, a group of inherited red blood cell disorders. (Source: WebMD Health)
Source: WebMD Health - July 13, 2020 Category: Consumer Health News Source Type: news

What People With Sickle Cell Disease Need to Know About COVID-19
MONDAY, July 13, 2020 -- People with sickle cell disease are at increased risk for severe complications from COVID-19, an expert says. " Many patients experience a pain crisis, also known as a vaso-occlusive crisis, early in COVID-19 infection... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 13, 2020 Category: General Medicine Source Type: news