Ghana: Sickle Cell Disease - the Place of Hydroxyurea in Treatment
[Ghanaian Times] I saw this vignette in the New England Journal of Medicine (NEJM). What follows by way of intervention, I believe, is still relevant. An 18-year-old woman with sickle cell anemia has had increasing symptoms, with painful crises and episodes of the acute chest syndrome. She was hospitalized three times in the past year. She was started on hydroxyurea therapy.(Orah S. PlattHydroxyurea for the Treatment of Sickle Cell Anemia.N Engl J Med 2008;358:1362-9). (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 16, 2021 Category: African Health Source Type: news

New study examines promising approach to treating attention and working memory difficulties in child
(Children's National Hospital) An adaptive cognitive training program could help treat attention and working memory difficulties in children with sickle cell disease (SCD), a new study published in the of Journal of Pediatric Psychology shows. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 7, 2021 Category: Biology Source Type: news

CRISPR-SNP-chip enables amplification-free electronic detection of single point mutations
(Keck Graduate Institute) Keck Graduate Institute (KGI) Assistant Professor and University of California, Berkeley Visiting Scientist Dr. Kiana Aran first introduced the CRISPR-Chip technology in 2019. Now just two years later, she has expanded on its application to develop CRISPR-SNP-Chip, which enables detection of single point mutations without amplification in Sickle Cell Disease and Amyotrophic lateral sclerosis (ALS). (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 5, 2021 Category: Biology Source Type: news

UC group launches clinical trial using CRISPR to correct sickle cell disease gene defect
Scientists at UCLA, UC San Francisco and UC Berkeley have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patients ’ own blood-forming stem cells.The trial will combine CRISPR technology developed at the Innovative Genomics Institute — a UC Berkeley–UCSF initiative founded by Berkeley’s Nobel Prize–winning scientist Jennifer Doudna — with UCLA’s expertise in genetic analysis and cell manufacturing, and the decades-long expertise at U...
Source: UCLA Newsroom: Health Sciences - March 30, 2021 Category: Universities & Medical Training Source Type: news

UC consortium launches first clinical trial using CRISPR to correct sickle cell gene
(University of California - San Francisco) Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 30, 2021 Category: International Medicine & Public Health Source Type: news

Small Business, Big Mission: Biotech company brings it all together
With early funding from California's Oakland-based stem cell research funding agency for its academic founders, the Stanford University spinout is tapping the CRISPR gene-editing technology out of UC Berkeley to push an experimental gene therapy for sickle cell disease into an early-stage clinical trial and pursue fixes for rare genetic diseases. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 26, 2021 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

A better treatment for sickle cell disease
(Texas A&M University) Sickle cell disease is the most prevalent inherited blood disorder in the world, affecting 70,000 to 100,000 Americans. However, it is considered an orphan disease, meaning it impacts less than 200,000 people nationally, and is therefore underrepresented in therapeutic research. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 24, 2021 Category: International Medicine & Public Health Source Type: news

New findings about immune system reaction to malaria and sickle cell disease
(University of Exeter) The researchers discovered that sugars called mannoses are expressed on the surfaces of both red blood cells infected with malarial parasites and also affected by sickle cell disease. The mannoses cause both infected cells and sickle cells to be eaten in the spleen.The team hope the findings will eventually help inform new treatments for malaria. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 19, 2021 Category: Infectious Diseases Source Type: news

With one sickle cell drug approved, Peninsula drug maker licenses two more
As potential one-shot-and-done gene therapies beckon for sickle cell disease patients, this South San Francisco pioneer is adding to its portfolio of tablets and pills. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - March 16, 2021 Category: Biotechnology Source Type: news

With one sickle cell drug approved, Peninsula drug maker licenses two more
As potential one-shot-and-done gene therapies beckon for sickle cell disease patients, this South San Francisco pioneer is adding to its portfolio of tablets and pills. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 16, 2021 Category: Pharmaceuticals Source Type: news

< a href= " /news-events/nih-research-matters/mitochondrial-dna-involved-sickle-cell-disease " > Mitochondrial DNA involved in sickle cell disease < /a >
People with sickle cell disease have high levels of mitochondrial DNA in their blood, which may help trigger damaging inflammation. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 16, 2021 Category: Consumer Health News Source Type: news

Stanford gene-editing startup raises $150M for sickle cell clinical trial, expansion into rare diseases
The South San Francisco company's early work at Stanford — as well as the work of a critical partner — was backed by grants from California's stem cell research funding agency CIRM. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 15, 2021 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

Gene Therapy for Sickle Cell Did Not Cause Patient's Leukemia
THURSDAY, March 11, 2021 -- There is no evidence that a promising gene therapy for sickle cell disease triggered leukemia in a patient, according to the company testing the experimental treatment. Bluebird Bio announced a few weeks ago that a sickle... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 11, 2021 Category: Pharmaceuticals Source Type: news

Gene Therapy for Sickle Cell Not Linked to Cancer, Bluebird Finds
Clinical trials were halted after DNA from the treatment's vector that ferries in the healthy genetic sequence was identified in the genome of a patient's cancer cells. (Source: The Scientist)
Source: The Scientist - March 11, 2021 Category: Science Tags: News & Opinion Source Type: news

Severe COVID-19 With ARDS in a Sickle Cell Disease Patient Severe COVID-19 With ARDS in a Sickle Cell Disease Patient
This case of ARDS caused by COVID-19 in a man with sickle cell disease helps further our understanding of how COVID-19 impacts these patients.BMC Pulmonary Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 11, 2021 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

Sickle Cell Treatment Not Linked to Cancer, Researchers Say
Trials of experimental gene therapy for sickle cell disease were halted when patients developed worrying illnesses. (Source: NYT Health)
Source: NYT Health - March 10, 2021 Category: Consumer Health News Authors: Gina Kolata Tags: Genetics and Heredity Leukemia Clinical Trials DNA (Deoxyribonucleic Acid) Sickle Cell Anemia Bluebird Bio Inc Boston Children ' s Hospital Gene Therapy Source Type: news

Kidney Transplant Tied to Reduced Mortality in Sickle Cell Patients Kidney Transplant Tied to Reduced Mortality in Sickle Cell Patients
Although the benefits of kidney transplant are similar for sickle cell patients, a new study suggests that sickle cell patients are much less likely to receive organs.Reuters Health Information (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - March 5, 2021 Category: Transplant Surgery Tags: Nephrology News Source Type: news

NIH scientists discover how DNA fragments can trigger inflammation in sickle cell disease
Finding could lead to new ways to reduce complications from painful red blood cell disorder. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - March 4, 2021 Category: American Health Source Type: news

Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells
We report an immunodeficient murine model in which combined human liver and cytokine humanization confer enhanced human erythropoiesis and RBC survival in the circulation. We deleted the fumarylacetoacetate hydrolase (Fah) gene in MISTRG mice expressing several human cytokines in place of their murine counterparts. Liver humanization by intrasplenic injection of human hepatocytes (huHep) eliminated murine complement C3 and reduced murine Kupffer cell density. Engraftment of human sickle cell disease (SCD)–derived hematopoietic stem cells in huHepMISTRGFah–/– mice resulted in vaso-occlusion that replicated...
Source: ScienceNOW - March 4, 2021 Category: Science Authors: Song, Y., Shan, L., Gbyli, R., Liu, W., Strowig, T., Patel, A., Fu, X., Wang, X., Xu, M. L., Gao, Y., Qin, A., Bruscia, E. M., Tebaldi, T., Biancon, G., Mamillapalli, P., Urbonas, D., Eynon, E., Gonzalez, D. G., Chen, J., Krause, D. S., Alderman, J., Hale Tags: Medicine, Diseases r-articles Source Type: news

Patients With Sickle Cell Disease Often Overlooked for Life-Saving Kidney Transplants
WEDNESDAY, March 3, 2021 -- People with kidney failure related to sickle cell disease are less likely to receive a transplant than those without sickle cell disease, but it could be life-saving for them, a new study finds. Sickle cell disease is a... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 3, 2021 Category: General Medicine Source Type: news

Patients With Sickle Cell Disease Often Overlooked for Life-Saving Kidney Transplants
Title: Patients With Sickle Cell Disease Often Overlooked for Life-Saving Kidney TransplantsCategory: Health NewsCreated: 3/3/2021 12:00:00 AMLast Editorial Review: 3/3/2021 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - March 3, 2021 Category: Anesthesiology Source Type: news

Addressing a complex world of pain in a single gene difference
(Wiley) A new review published by Wiley in the journal Advanced Genetics analyzes disparities in experience and treatment of sickle cell disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Transplant Beneficial for Kidney Failure in Sickle Cell
Patients with kidney failure associated with sickle cell disease are less likely to receive a transplant despite similar reduction in mortality (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 26, 2021 Category: Cancer & Oncology Tags: Nephrology, Oncology, Surgery, Journal, Source Type: news

Transplant Beneficial for Kidney Failure in Sickle Cell
FRIDAY, Feb. 26, 2021 -- Patients with kidney failure who receive a kidney transplant, including those with sickle cell disease, have lower mortality, according to a study published online Feb. 25 in the Clinical Journal of the American Society of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 26, 2021 Category: Pharmaceuticals Source Type: news

FDA Places Clinical Hold on Sickle Cell Gene Therapy FDA Places Clinical Hold on Sickle Cell Gene Therapy
FDA placed a clinical hold on two gene therapy clinical trials for sickle cell disease after two patients developed blood diseases.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 25, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Trial of Gene Therapy for Sickle Cell Disease Halted
Two patients participating in the study developed cancer years after treatment (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 24, 2021 Category: Cancer & Oncology Tags: Oncology, Pathology, Institutional, Source Type: news

Trial of Gene Therapy for Sickle Cell Disease Halted
TUESDAY, Feb. 23, 2021 -- A clinical trial of a new gene therapy for sickle cell disease that has shown promise has been halted after two participants were diagnosed with cancer. Therapy developer Bluebird Bio said a patient who was treated five... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 23, 2021 Category: Pharmaceuticals Source Type: news

Researchers Halt Trials of Promising Sickle Cell Treatment
Two patients in a gene therapy study developed cancer years after treatment. It is not clear whether the therapy was responsible. (Source: NYT Health)
Source: NYT Health - February 23, 2021 Category: Consumer Health News Authors: Gina Kolata Tags: Sickle Cell Anemia Genetic Engineering Leukemia Bluebird Bio Inc Bone Marrow Clinical Trials DNA (Deoxyribonucleic Acid) Drugs (Pharmaceuticals) National Heart, Lung and Blood Institute Busulfan Black People Source Type: news

Health Highlights: Feb. 23, 2021
  Trial of Gene Therapy for Sickle Cell Disease Halted A clinical trial of a new gene therapy for sickle cell disease that's shown promise has been halted after two participants were diagnosed with cancer. Therapy developer Bluebird Bio said... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 23, 2021 Category: General Medicine Source Type: news

Researchers Halt Trial of Promising Sickle Cell Treatment
Two patients in a gene therapy study developed cancer years after treatment. It is not clear whether the therapy was responsible. (Source: NYT Health)
Source: NYT Health - February 22, 2021 Category: Consumer Health News Authors: Gina Kolata Tags: Sickle Cell Anemia Leukemia Bone Marrow Genetic Engineering Clinical Trials Bluebird Bio Inc Williams, David II DNA (Deoxyribonucleic Acid) National Heart, Lung and Blood Institute Busulfan Drugs (Pharmaceuticals) Source Type: news

After the Nobel, what next for Crispr  gene-editing therapies?
Hailed as the ‘molecular scissors’ that will allow us to rewrite our genes, the DNA tool is being trialled in treatments for everything from sickle-cell anaemia to cancerWhen last year ’s Nobel prize for chemistry was awarded tobiochemist Jennifer Doudna and microbiologist Emmanuelle Charpentier for their work in developing the technique of gene editing known as Crispr-Cas9 (pronounced “crisper”), headlines hailed their discovery as “molecular scissors” that would allow us to “rewrite the book of life” – with all the complicated ethical questions that ability rais...
Source: Guardian Unlimited Science - February 21, 2021 Category: Science Authors: Philip Ball Tags: Gene editing Medical research Genetics Biology Science Cancer Huntington's disease Sickle cell disease Source Type: news

Shares plummet as bluebird bio suspends trials of sickle-cell anemia drug
Shares of bluebird bio hit their lowest value in more than six years after the Cambridge-based company suspended two trials of its gene therapy for sickle-cell anemia due to fears of serious side effects. Bluebird announced that it has temporarily suspended both an early-stage and a late-stage trial of bb1111 after it learned that blood cancer has been diagnosed in two former trial subjects. One patient who was treated with bb1111 “more than five years ago” was diagnosed with acute myeloid leuk emia,… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - February 16, 2021 Category: Health Management Authors: Don Seiffert Source Type: news

New Gene Therapy Vector Promising for Sickle Cell, Beta-Thalassemia New Gene Therapy Vector Promising for Sickle Cell, Beta-Thalassemia
A new lentiviral gene therapy vector, ALS20, triggers more hemoglobin production at a lower dose than vectors currently used in trials of blood disorders such as sickle cell disease and beta-thalassemia, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 11, 2021 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Genome-editing tool TALEN outperforms CRISPR-Cas9 in tightly packed DNA
(University of Illinois at Urbana-Champaign, News Bureau) Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN. Their experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in parts of the genome, called heterochromatin, that are densely packed. Fragile X syndrome, sickle cell anemia, beta-thalassemia and other diseases are the result of genetic defects in the heterochromatin. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 27, 2021 Category: International Medicine & Public Health Source Type: news

Rethinking rideshares: a transportation assistance pilot for pediatric patients with sickle cell disease - Vais S, Thomson L, Williams A, Sobota A.
This study assesses the efficacy of heal... (Source: SafetyLit)
Source: SafetyLit - January 11, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

mRNA Technology Gave Us the First COVID-19 Vaccines. It Could Also Upend the Drug Industry
“No!” The doctor snapped. “Look at me!” I had been staring her in the eyes, as she had ordered, but when a doctor on my other side began jabbing me with a needle, I started to turn my head. “Don’t look at it,” the first doctor said. I obeyed. This was in early August in New Orleans, where I had signed up to be a participant in the clinical trial for the Pfizer-BioNTech COVID-19 vaccine. It was a blind study, which meant I was not supposed to know whether I had gotten the placebo or the real vaccine. I asked the doctor if I would really been able to tell by looking at the syringe. &...
Source: TIME: Health - January 11, 2021 Category: Consumer Health News Authors: Walter Isaacson Tags: Uncategorized COVID-19 feature Magazine Source Type: news

mRNA Technology Gave Us the First COVID-19 Vaccines. It Could Also Upend the Drug Industry
“No!” The doctor snapped. “Look at me!” I had been staring her in the eyes, as she had ordered, but when a doctor on my other side began jabbing me with a needle, I started to turn my head. “Don’t look at it,” the first doctor said. I obeyed. This was in early August in New Orleans, where I had signed up to be a participant in the clinical trial for the Pfizer-BioNTech COVID-19 vaccine. It was a blind study, which meant I was not supposed to know whether I had gotten the placebo or the real vaccine. I asked the doctor if I would really been able to tell by looking at the syringe. &...
Source: TIME: Science - January 11, 2021 Category: Science Authors: Walter Isaacson Tags: Uncategorized COVID-19 feature Magazine Source Type: news

Sickle-Cell Trait May Not Independently Elevate CHD Risk Sickle-Cell Trait May Not Independently Elevate CHD Risk
Coronary heart disease didn't seem to explain the risk of sudden death associated with the trait in a combined analysis of five major population-based studies.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 9, 2021 Category: Cancer & Oncology Tags: Cardiology News Source Type: news

Study: Sickle cell trait does not increase heart disease risk in African Americans
Carrying the sickle cell trait does not play a significant role in the increased risk for coronary heart disease among African Americans, a study published Tuesday by JAMA Network Open found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - January 5, 2021 Category: Consumer Health News Source Type: news

Updated advice on COVID-19 vaccination in pregnancy and women who are breastfeeding, RCOG
The Government has today accepted the recommendation from the Medicines and Healthcare products Regulatory Agency (MHRA) to authorise Oxford University/AstraZeneca's COVID-19 vaccine for use. The Joint Committee on Vaccination and Immunisation (JCVI) has also published its latest advice for the priority groups to receive the Oxford University/AstraZeneca and the Pfizer/BioNTech vaccines. This includes updated advice for pregnant and breastfeeding women who meet other criteria for priority vaccination. The JCVI confirms that although the available data do not indicate any safety concern or harm to pregnancy, there is insuf...
Source: Current Awareness Service for Health (CASH) - December 31, 2020 Category: Consumer Health News Source Type: news

Sickle Cell Puts Black Patients at Higher Risk for Severe COVID
TUESDAY, Dec. 15, 2020 -- Sickle cell disease increases the risk of death or serious complications from COVID-19 infection, a pair of new studies suggests. People with sickle cell disease -- a genetic blood disorder predominantly found in Black... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 15, 2020 Category: General Medicine Source Type: news

Uganda: Sickle Cell Warriors Receive Phones With Health App for Quick Treatment During Tough Covid-19 Times
[Monitor] At least 10,000 people living with sickle cell anemia, are each to be availed with a smart phone that they can make use of to get treatment from a doctor given the ongoing restrictions caused by Covid-19. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 15, 2020 Category: African Health Source Type: news

Sickle Cell Puts Black Patients at Higher Risk for Severe COVID
Title: Sickle Cell Puts Black Patients at Higher Risk for Severe COVIDCategory: Health NewsCreated: 12/15/2020 12:00:00 AMLast Editorial Review: 12/15/2020 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - December 15, 2020 Category: Anesthesiology Source Type: news

Could Gene Therapy Cure Sickle Cell Disease? Two New Studies Raise Hopes
Title: Could Gene Therapy Cure Sickle Cell Disease? Two New Studies Raise HopesCategory: Health NewsCreated: 12/5/2020 12:00:00 AMLast Editorial Review: 12/7/2020 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - December 7, 2020 Category: Anesthesiology Source Type: news

Gene-editing treatment shows promise for sickle cell disease
Scientists are seeing promising early results from the first studies testing gene editing for painful, inherited blood disorders that plague millions worldwide, especially Black people (Source: ABC News: Health)
Source: ABC News: Health - December 5, 2020 Category: Consumer Health News Tags: Health Source Type: news

Could Gene Therapy Cure Sickle Cell Disease? Two New Studies Raise Hopes
SATURDAY, Dec. 5, 2020 -- A pair of new gene therapies promise a potentially lasting cure for sickle cell disease by subtly altering the genetic information in patients'bone marrow cells, researchers report. Both therapies work by switching on a... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 5, 2020 Category: General Medicine Source Type: news

Integrated anemia-SCD test demonstrates accurate results in study at 2020 ASH meeting
(Whitecoat Strategies, LLC) Researchers from Case Western Reserve University presented research today in which Hemex Health's affordable Gazelle platform diagnostic technology successfully tested 46 patients with 100% sensitivity and over 92.3% specificity for anemia and with 100% accuracy for hemoglobin variants. The preliminary study included blood samples collected from Cleveland-area patients studied for anemia and sickle cell disease. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 5, 2020 Category: Infectious Diseases Source Type: news

UCLA receives $7.3 million grant to build state-of-the-art facility for developing gene, cell therapies
UCLA has received a $7.3 million grant from the National Institutes of Health to build a state-of-the-art facility in which to produce gene and cell therapies aimed at treating a host of illnesses and conditions.The new 13,000-square-foot facility, to be constructed in UCLA ’s Center for the Health Sciences, will provide a highly regulated environment with features such as systems to manage air flow and filtering, laboratory spaces and bioreactors. The new facility is expected to be ready for use in 2023.“This grant provides critical funds to build a facility that will enable the development of a new generation...
Source: UCLA Newsroom: Health Sciences - December 4, 2020 Category: Universities & Medical Training Source Type: news

Gene therapy gives man with sickle cell disease the chance for a better future
For Evie Junior, living with sickle cell disease has been like running a marathon.“But it’s a marathon where as you keep going, the trail gets rockier and then you lose your shoes,” the 27-year-old said. “It gets harder as you get older. Things start to fail and all you can think about is how much worse it’s going to get down the road.”In sickle cell disease, a genetic mutation causes the blood-forming stem cells — which give rise to all blood and immune cells — to produce hard, sickle-shaped red blood cells. These misshapen cells die early, leaving an insufficient numbe...
Source: UCLA Newsroom: Health Sciences - November 30, 2020 Category: Universities & Medical Training Source Type: news

Gene therapy gives man with sickle cell disease the chance for a better future
(University of California - Los Angeles Health Sciences) Watch a video about Evie's treatment with an experimental gene therapy for sickle cell disease here: https://www.youtube.com/watch?v=XmQJpuLx07Y (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 30, 2020 Category: International Medicine & Public Health Source Type: news