Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
Conditions: Pain; Sickle Cell Disease Interventions: Behavioral: CBT+ Health coach; Behavioral: CBT w/o Health Coach ( self-guided); Behavioral: Usual Care Sponsors: University of Pittsburgh; National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials

School Readiness Intervention for Preschool Children With Sickle Cell Disease
Conditions: Sickle Cell Disease Interventions: Device: The adapted Kids in Transition to School Intervention; Device: Standard school resources Sponsors: St. Jude Children ' s Research Hospital; National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301
Conditions: Sickle Cell Disease; Transfusion-dependent Beta-Thalassemia; Hemoglobinopathies Interventions: Other: Safety and efficacy assessments Sponsors: Editas Medicine, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell AntibodY
Conditions: Sickle Cell Disease Interventions: Drug: Daratumumab; Drug: Alemtuzumab; Drug: Sirolimus; Radiation: Total Body Irradiation Sponsors: Children ' s National Research Institute; Alberta Children ' s Hospital; The Hospital for Sick Children; Levine Children ' s Hospital; Ann& Robert H Lurie Children ' s Hospital of Chicago; Nationwide Children ' s Hospital; Children ' s Hospital at Montefiore; Doris Duke Charitable Foundation; Janssen Pharmaceuticals Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials

Comparative Health Status and Quality of Life of Patients With Sickle Cell Disease (SCD) Who Underwent Matched-sibling Hematopoietic Stem Cell Transplantation Versus Non Transplanted SCD Case-control Patients
Conditions: Sickle Cell Disease Interventions: Other: Spermogram; Other: Hospital Anxiety and Depression Scale (HADS); Other: SF36 Quality of life questionnaire; Other: Psychologist interview; Other: Optional sera banking; Other: Optional DNA banking Sponsors: Assistance Publique - H ôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 8, 2024 Category: Research Source Type: clinical trials

Sex Hormones and Inflammatory Biomarkers in Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease; Vaso-occlusive Crisis Sponsors: University of Pennsylvania Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 3, 2024 Category: Research Source Type: clinical trials

mAnaging siCkle CELl disEase Through incReased AdopTion of hydroxyurEa in Nigeria
Conditions: Sickle Cell Disease Interventions: Behavioral: TASSH Sponsors: New York University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2024 Category: Research Source Type: clinical trials

Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department
Conditions: Sickle-Cell Disease With Crisis Interventions: Drug: Parecoxib; Drug: Morphine Sponsors: Oman Medical Speciality Board; Armed Forces Hospital, Oman Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials

Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling
Conditions: Sickle Cell Disease; Thalassemia; Hemoglobinopathy Interventions: Biological: Biotin-labeled red blood cells Sponsors: National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

Uganda Sickle Surveillance Study (US-3)
Conditions: Sickle Cell Disease Sponsors: Children ' s Hospital Medical Center, Cincinnati; Makerere University; Ministry of Health, Uganda; Mulago Hospital, Uganda Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials

Clinical Study of BRL-101 in Severe SCD
Conditions: Sickle Cell Disease Interventions: Drug: Autologous hematopoietic stem and progenitor cells injection Sponsors: Bioray Laboratories; First Affiliated Hospital of Guangxi Medical University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials

Effect of Empowerment-Based Interventions on Self-Efficacy and Self-Care Capacity Among Adults With Sickle Cell Disease
Conditions: Self-Efficacy; Self-Care Interventions: Behavioral: Empowerment-Based Interventions; Behavioral: Standard Health Education Sponsors: University of Bahrain Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2024 Category: Research Source Type: clinical trials

Patient and Public Involvement and Engagement in Research With Children and Young People With Sickle Cell Disorder and Their Families
Conditions: Sickle Cell Disease Sponsors: King ' s College London; Sickle Cell Society Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials

A Socio-ecological Approach for Improving Self-management in Adolescents With SCD
Conditions: Anemia, Sickle Cell Interventions: Behavioral: SCThrive; Other: SCHealthED Sponsors: Children ' s Hospital Medical Center, Cincinnati; Nemours Children ' s Health System; Emory University; Children ' s Hospital of Philadelphia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials

Clinical Study on the Safety and Efficacy of BRL-101 in the Treatment of Sickle Cell Disease
Conditions: Sickle Cell Disease Interventions: Drug: BRL-101 autologous hematopoietic stem and progenitor cells injection Sponsors: Bioray Laboratories; Hospital of Hematology, Chinese Academy of Medical Sciences (Institute of Hematology, Chinese Academy of Medical Sciences) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials