microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Reproductive Biology - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
microRNAs in the pathogenesis of non-obstructive azoospermia: the underlying mechanisms and therapeutic potentials
Syst Biol Reprod Med. 2021 Aug 6:1-17. doi: 10.1080/19396368.2021.1951890. Online ahead of print.ABSTRACTmiRNAs are involved in different biological processes, including proliferation, differentiation, and apoptosis. Interestingly, 38% of the X chromosome-linked miRNAs are testis-specific and have crucial roles in regulating the renewal and cell cycle of spermatogonial stem cells. Previous studies demonstrated that abnormal expression of spermatogenesis-related miRNAs could lead to nonobstructive azoospermia (NOA). Moreover, differential miRNAs expression in seminal plasma of NOA patients has been reported compared to norm...
Source: Systems Biology in Reproductive Medicine - August 6, 2021 Category: Reproduction Medicine Authors: Yeganeh Rastgar Rezaei Reza Zarezadeh Saba Nikanfar Hajar Oghbaei Nahideh Nazdikbin Zahra Bahrami-Asl Nosratollah Zarghami Yadollah Ahmadi Amir Fattahi Mohammad Nouri Ralf Dittrich Source Type: research
Diagnosis and treatment of rare testicular tumors using the example of malignant mesothelioma of the tunica vaginalis testis and Sertoli cell tumors
CONCLUSION: Systematic registration of rare testicular tumors and comprehensive molecular pathological analysis are urgently needed to improve the understanding of tumor biology and to develop new therapeutic strategies.PMID:34185119 | DOI:10.1007/s00120-021-01575-9 (Source: Der Urologe. Ausg. A)
Source: Der Urologe. Ausg. A - June 29, 2021 Category: Urology & Nephrology Authors: G von Amsberg M Sehovic M Hartmann C Bokemeyer Source Type: research
Diagnosis and treatment of rare testicular tumors using the example of malignant mesothelioma of the tunica vaginalis testis and Sertoli cell tumors
CONCLUSION: Systematic registration of rare testicular tumors and comprehensive molecular pathological analysis are urgently needed to improve the understanding of tumor biology and to develop new therapeutic strategies.PMID:34185119 | DOI:10.1007/s00120-021-01575-9 (Source: Der Urologe. Ausg. A)
Source: Der Urologe. Ausg. A - June 29, 2021 Category: Urology & Nephrology Authors: G von Amsberg M Sehovic M Hartmann C Bokemeyer Source Type: research
