Effects of Aqueous Saffron Extract on Glucoregulation as Well as Hepatic Agt and TNF- α Gene Expression in Rats Subjected to Sub-Chronic Stress
CONCLUSION: Saffron treatment after sub-chronic stress not only did not improve glucose tolerance but also enhanced insulin resistance. It indicated the interaction of saffron and sub-chronic stress to promote renin-angiotensin system activity. In addition, the saffron treatment decreased TNF-α gene expression after sub-chronic stress. The synergistic stimulating effect of saffron and sub-chronic stress on gene expression of hepatic Agt led to insulin resistance and hyperglycemia.PMID:37434936 | PMC:PMC10331535 | DOI:10.4103/abr.abr_51_22 (Source: Biomed Res)
Source: Biomed Res - July 12, 2023 Category: Research Authors: Yeganeh Yazdani Maryam Radahmadi Roshanak Roustazade Source Type: research
Effects of Aqueous Saffron Extract on Glucoregulation as Well as Hepatic Agt and TNF- α Gene Expression in Rats Subjected to Sub-Chronic Stress
CONCLUSION: Saffron treatment after sub-chronic stress not only did not improve glucose tolerance but also enhanced insulin resistance. It indicated the interaction of saffron and sub-chronic stress to promote renin-angiotensin system activity. In addition, the saffron treatment decreased TNF-α gene expression after sub-chronic stress. The synergistic stimulating effect of saffron and sub-chronic stress on gene expression of hepatic Agt led to insulin resistance and hyperglycemia.PMID:37434936 | PMC:PMC10331535 | DOI:10.4103/abr.abr_51_22 (Source: Biomed Res)
Source: Biomed Res - July 12, 2023 Category: Research Authors: Yeganeh Yazdani Maryam Radahmadi Roshanak Roustazade Source Type: research
[ASAP] Saffron Petal, an Edible Byproduct of Saffron, Alleviates Dextran Sulfate Sodium-Induced Colitis by Inhibiting Macrophage Activation and Regulating Gut Microbiota
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.2c07915 (Source: Journal of Agricultural and Food Chemistry)
Source: Journal of Agricultural and Food Chemistry - July 5, 2023 Category: Food Science Authors: Jiao Peng, Huan Deng, Bin Du, Peigen Wu, Lifang Duan, Ronghe Zhu, Ziwan Ning, Jinxiu Feng, and Haitao Xiao Source Type: research
Spices and Biomarkers of COVID-19: A Mechanistic and Therapeutic Perspective
Adv Exp Med Biol. 2023;1412:375-395. doi: 10.1007/978-3-031-28012-2_20.ABSTRACTIn the face of the COVID-19 pandemic, many people around the world have increased their healthy behaviors to prevent transmission of the virus and potentially improve their immune systems. Therefore, the role of diet and food compounds such as spices with bioactive and antiviral properties may be important in these efforts. In this chapter, we review the efficacy of spices such as turmeric (curcumin), cinnamon, ginger, black pepper, saffron, capsaicin, and cumin by investigating the effects of these compounds of COVID-19 disease severity biomark...
Source: Advances in Experimental Medicine and Biology - June 28, 2023 Category: Research Authors: Masha Shirani Shokoofeh Talebi Mehrnaz Shojaei Gholamreza Askari Mohammad Bagherniya Paul C Guest Thozhukat Sathyapalan Amirhossein Sahebkar Source Type: research
Predictive saccades and decision making in the beetle-predating saffron robber fly
Curr Biol. 2023 Jun 20:S0960-9822(23)00770-4. doi: 10.1016/j.cub.2023.06.019. Online ahead of print.ABSTRACTInternal predictions about the sensory consequences of self-motion, encoded by corollary discharge, are ubiquitous in the animal kingdom, including for fruit flies, dragonflies, and humans. In contrast, predicting the future location of an independently moving external target requires an internal model. With the use of internal models for predictive gaze control, vertebrate predatory species compensate for their sluggish visual systems and long sensorimotor latencies. This ability is crucial for the timely and accura...
Source: Current Biology - June 28, 2023 Category: Biology Authors: Jennifer Talley Siddhant Pusdekar Aaron Feltenberger Natalie Ketner Johnny Evers Molly Liu Atishya Gosh Stephanie E Palmer Trevor J Wardill Paloma T Gonzalez-Bellido Source Type: research
Spices and Biomarkers of COVID-19: A Mechanistic and Therapeutic Perspective
Adv Exp Med Biol. 2023;1412:375-395. doi: 10.1007/978-3-031-28012-2_20.ABSTRACTIn the face of the COVID-19 pandemic, many people around the world have increased their healthy behaviors to prevent transmission of the virus and potentially improve their immune systems. Therefore, the role of diet and food compounds such as spices with bioactive and antiviral properties may be important in these efforts. In this chapter, we review the efficacy of spices such as turmeric (curcumin), cinnamon, ginger, black pepper, saffron, capsaicin, and cumin by investigating the effects of these compounds of COVID-19 disease severity biomark...
Source: Advances in Experimental Medicine and Biology - June 28, 2023 Category: Research Authors: Masha Shirani Shokoofeh Talebi Mehrnaz Shojaei Gholamreza Askari Mohammad Bagherniya Paul C Guest Thozhukat Sathyapalan Amirhossein Sahebkar Source Type: research
A novel anchoring system for pelvic organ prolapse repair: an observational study
ConclusionThe innovative anchoring device that was developed appeared to enable precise and solid anchor placement in the SSL. Future clinical studies are needed to explore if the theoretical advantages of this device translate to improved clinical outcomes in comparison with available suturing and anchoring devices. (Source: International Urogynecology Journal)
Source: International Urogynecology Journal - June 23, 2023 Category: OBGYN Source Type: research
Identification and characterization of pathogens causing saffron corm rot in China
Corm rot is the most important disease of saffron, for which fungi from several genus such as Fusarium spp. Penicillium spp. and Botrytis spp., have been previously reported to be the pathogens. In this research, we used a combination of amplicon sequencing and traditional isolation methods to identify the causal agents, main infection source. The diversity of microbial communities in diseased saffron corms and soil decreased significantly compared with healthy corms and soil. The contents of Penicillium and Botrytis in healthy and diseased corms were similarly high, indicating that them were not directly related to the oc...
Source: Frontiers in Microbiology - June 9, 2023 Category: Microbiology Source Type: research
Evaluation of Saffron (Crocus Sativus L) Effects on Anxiety in Hospitalized Patients with Acute Coronary Syndrome
CONCLUSION: The present study did not corroborate the therapeutic effects of saffron on reducing anxiety in patients with ACS.PMID:37288021 | PMC:PMC10241615 | DOI:10.4103/abr.abr_6_21 (Source: Biomed Res)
Source: Biomed Res - June 8, 2023 Category: Research Authors: Fariba Askari Jamal Seidi Mohammad Khaled Naqshbandi Hajar Kashefi Sholeh Shami Source Type: research
Evaluation of Saffron (Crocus Sativus L) Effects on Anxiety in Hospitalized Patients with Acute Coronary Syndrome
CONCLUSION: The present study did not corroborate the therapeutic effects of saffron on reducing anxiety in patients with ACS.PMID:37288021 | PMC:PMC10241615 | DOI:10.4103/abr.abr_6_21 (Source: Biomed Res)
Source: Biomed Res - June 8, 2023 Category: Research Authors: Fariba Askari Jamal Seidi Mohammad Khaled Naqshbandi Hajar Kashefi Sholeh Shami Source Type: research
Global funding for cancer research between 2016 and 2020: a content analysis of public and philanthropic investments
Lancet Oncol. 2023 Jun;24(6):636-645. doi: 10.1016/S1470-2045(23)00182-1.ABSTRACTBACKGROUND: Cancer is a leading cause of disease burden globally, with more than 19·3 million cases and 10 million deaths recorded in 2020. Research is crucial to understanding the determinants of cancer and the effects of interventions, and to improving outcomes. We aimed to analyse global patterns of public and philanthropic investment in cancer research.METHODS: In this content analysis, we searched the UberResearch Dimensions database and Cancer Research UK data for human cancer research funding awards from public and philanthropic funder...
Source: Cancer Control - June 3, 2023 Category: Cancer & Oncology Authors: Stuart A McIntosh Fareeha Alam Laura Adams Ian S Boon Jonathan Callaghan Isabella Conti Ellen Copson Victoria Carson Mitchell Davidson Helen Fitzgerald Ashram Gautam Christopher M Jones Saffron Kargbo Gokul Lakshmipathy Hannah Maguire Kathryn McFerran Ama Source Type: research
