Potential of using microalgae to sequester carbon dioxide and processing to bioproducts
Green Chem., 2023, Advance Article DOI: 10.1039/D3GC02286B, Critical ReviewVenkatesh Balan, James Pierson, Hasan Husain, Sandeep Kumar, Christopher Saffron, Vinod Kumar Microalgae could be sustainably used to sequester CO2 and processed to fuels and chemicals. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Green Chem. latest articles)
Source: RSC - Green Chem. latest articles - September 15, 2023 Category: Chemistry Authors: Venkatesh Balan Source Type: research
Quercetin inhibits the metabolism of arachidonic acid by inhibiting the activity of CYP3A4, thereby inhibiting the progression of breast cancer
CONCLUSION: Quercetin could inhibit the activity of CYP3A to down-regulate AA metabolites EETs, consequently hampering p-Stat3 and nuclear translocation, thus impeding BC development.PMID:37710176 | DOI:10.1186/s10020-023-00720-8 (Source: Molecular Medicine)
Source: Molecular Medicine - September 14, 2023 Category: Molecular Biology Authors: Huaming Tang Yuanli Kuang Wan Wu Bing Peng Qianmei Fu Source Type: research
Identification of the therapeutic mechanism of the saffron crocus on glioma through network pharmacology and bioinformatics analysis
AbstractSaffron crocus is a herbal medicine of traditional Tibetan medicine (TTM). Saffron extract has been indicated to inhibit tumor cell growth and promote tumor cell apoptosis in a variety of cancers, including glioma, but the specific mechanism is not clear. To study the possible mechanism of saffron action on glioma, network pharmacology and bioinformatics analysis methods were used in this study. We used the online database to obtain the active ingredients of saffron and their targets. Glioma-related targets were also acquired from online database. We intersected drug targets with glioma-related targets and conducte...
Source: Medical Oncology - September 10, 2023 Category: Cancer & Oncology Source Type: research
GSE103987 MAP3K8 is a major regulator of inflammation in human airway epithelial cells
Contributors : Chih-Yung Chiu ; Saffron A Willis-Owen ; Kenny C Wong ; Stuart N Farrow ; Youming Zhang ; Miriam F Moffatt ; William O CooksonSeries Type : Expression profiling by arrayOrganism : Homo sapiensIn this experiment we catalogue temporal variation in transcription occurring during IL1B stimulation under control (non-targeting siRNA control) conditions and partial MAP3K8 siRNA knockdown in the A549 cell line. We measure global gene transcription at 0, 1, 2, 4, 6, 8, and 12 hours using Affymetrix HuGene 1.1 ST array. Nineteen genes demonstrated a distinct temporal response to Il1B stimulation following suppressio...
Source: GEO: Gene Expression Omnibus - September 9, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
< i > In silico < /i > and < i > in vitro < /i > potentials of crocin and amphotericin B on < i > Leishmania major < /i > : Multiple synergistic mechanisms of actions
In conclusion, crocin with AmpB synergistically exertedin vitro antileishmanial action, generated nitric oxide and reactive oxygen species, modulated Th1, and Th2 phenotypes and transfer factors, enhanced PCD profile and arrested the cell cycle ofLeishmania major promastigotes. The main action of crocin and AmpB involved wide-ranging mechanistic insights for conducting other clinical settings as promising drug candidates for cutaneous leishmaniasis. Therefore, this combination could be esteemed as a basis for a potential bioactive component and a logical source for leishmanicidal drug development against CL in future advan...
Source: PLoS One - September 8, 2023 Category: Biomedical Science Authors: Ehsan Salarkia Source Type: research
Phytochemistry, quality control and medicinal uses of Saffron ( < em > Crocus sativus L < /em > .): an updated review
J Med Life. 2023 Jun;16(6):822-836. doi: 10.25122/jml-2022-0353.ABSTRACTSaffron, botanically known as Crocus sativus L., is renowned as the world's most expensive spice and has been utilized in various fields since ancient times. Extensive scientific research has been conducted on Crocus sativus (C. sativus), focusing on its phytochemical composition, diverse applications, and biological activities. C. sativus phytochemicals consist mainly of three compounds, namely crocin, picrocrocin, and safranal, which are responsible for most of its properties. Saffron is rich in bioactive compounds, more than 150 of which have been i...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Rabha Aissa Mohamed Ibourki Hasna Ait Bouzid Laila Bijla Samira Oubannin El Hassan Sakar Simohamed Jadouali Andi Hermansyah Khang Wen Goh Long Chiau Ming Abdelhakim Bouyahya Said Gharby Source Type: research
