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Total 4663 results found since Jan 2013.
Diagnostic potential of serum miR-532-3p as a circulating biomarker for experimental intrinsic drug-induced liver injury by acetaminophen and cisplatin in rats
Food Chem Toxicol. 2023 Jun 10;178:113890. doi: 10.1016/j.fct.2023.113890. Online ahead of print.ABSTRACTEvaluating tissue injury largely depends on serum biochemical analysis despite insufficient tissue specificity and low sensitivity. Therefore, attention has been paid to the potential of microRNAs (miRNAs) to overcome the limitations of the current diagnostic tools, as tissue-enriched miRNAs are detected in the blood upon tissue injury. First, using a cisplatin-injected rats, we screened a specific pattern of altered hepatic miRNAs and their target mRNAs. Subsequently, we identified novel liver-specific circulating miRN...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Da-Bin Hwang Yoojin Seo Eunji Lee Dong-Hoon Won Changuk Kim MinHwa Kang Young Jeon Hyung-Sik Kim Jun Won Park Jun-Won Yun Source Type: research
Differences in Analgesia Methods for Open Gastrointestinal Surgery Are Not Associated With Initial Postoperative Ambulation
CONCLUSIONS: No significant differences were observed between different postoperative analgesia methods, suggesting that there may be no association between postoperative ambulation and the postoperative analgesia method.PMID:37303470 | PMC:PMC10251697 | DOI:10.14740/jocmr4899
Source: Clin Med Res - June 12, 2023 Category: Research Authors: Yuta Mitobe Takeshi Itou Yuri Yamaguchi Tomomi Yoshioka Kenji Nakagawa Source Type: research
Diagnostic potential of serum miR-532-3p as a circulating biomarker for experimental intrinsic drug-induced liver injury by acetaminophen and cisplatin in rats
Food Chem Toxicol. 2023 Jun 10:113890. doi: 10.1016/j.fct.2023.113890. Online ahead of print.ABSTRACTEvaluating tissue injury largely depends on serum biochemical analysis despite insufficient tissue specificity and low sensitivity. Therefore, attention has been paid to the potential of microRNAs (miRNAs) to overcome the limitations of the current diagnostic tools, as tissue-enriched miRNAs are detected in the blood upon tissue injury. First, using a cisplatin-injected rats, we screened a specific pattern of altered hepatic miRNAs and their target mRNAs. Subsequently, we identified novel liver-specific circulating miRNAs f...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Da-Bin Hwang Yoojin Seo Eunji Lee Dong-Hoon Won Changuk Kim MinHwa Kang Young Jeon Hyung-Sik Kim Jun Won Park Jun-Won Yun Source Type: research
Novel ruthenium-doped vanadium carbide/polymeric nanohybrid sensor for acetaminophen drug detection in human blood
Int J Biol Macromol. 2023 Jun 10:125329. doi: 10.1016/j.ijbiomac.2023.125329. Online ahead of print.ABSTRACTThe use of advanced electroactive catalysts enhances the performance of electrochemical biosensors in real-time biomonitoring and has received much attention owing to its excellent physicochemical and electrochemical possessions. In this work, a novel biosensor was developed based on the electrocatalytic activity of functionalized vanadium carbide (VC) material, including VC@ruthenium (Ru), VC@Ru-polyaniline nanoparticles (VC@Ru-PANI-NPs) as non-enzymatic nanocarriers for the fabrication of modified screen-printed el...
Source: International Journal of Biological Macromolecules - June 12, 2023 Category: Biochemistry Authors: Murugesan Duraisamy Mari Elancheziyan Muthusankar Eswaran Sivarasan Ganesan Anees A Ansari Govindaraj Rajamanickam Siew Ling Lee Pei-Chien Tsai Yi-Hsun Chen Vinoth Kumar Ponnusamy Source Type: research
Differences in Analgesia Methods for Open Gastrointestinal Surgery Are Not Associated With Initial Postoperative Ambulation
CONCLUSIONS: No significant differences were observed between different postoperative analgesia methods, suggesting that there may be no association between postoperative ambulation and the postoperative analgesia method.PMID:37303470 | PMC:PMC10251697 | DOI:10.14740/jocmr4899
Source: Clin Med Res - June 12, 2023 Category: Research Authors: Yuta Mitobe Takeshi Itou Yuri Yamaguchi Tomomi Yoshioka Kenji Nakagawa Source Type: research
Diagnostic potential of serum miR-532-3p as a circulating biomarker for experimental intrinsic drug-induced liver injury by acetaminophen and cisplatin in rats
Food Chem Toxicol. 2023 Jun 10;178:113890. doi: 10.1016/j.fct.2023.113890. Online ahead of print.ABSTRACTEvaluating tissue injury largely depends on serum biochemical analysis despite insufficient tissue specificity and low sensitivity. Therefore, attention has been paid to the potential of microRNAs (miRNAs) to overcome the limitations of the current diagnostic tools, as tissue-enriched miRNAs are detected in the blood upon tissue injury. First, using a cisplatin-injected rats, we screened a specific pattern of altered hepatic miRNAs and their target mRNAs. Subsequently, we identified novel liver-specific circulating miRN...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Da-Bin Hwang Yoojin Seo Eunji Lee Dong-Hoon Won Changuk Kim MinHwa Kang Young Jeon Hyung-Sik Kim Jun Won Park Jun-Won Yun Source Type: research
Differences in Analgesia Methods for Open Gastrointestinal Surgery Are Not Associated With Initial Postoperative Ambulation
CONCLUSIONS: No significant differences were observed between different postoperative analgesia methods, suggesting that there may be no association between postoperative ambulation and the postoperative analgesia method.PMID:37303470 | PMC:PMC10251697 | DOI:10.14740/jocmr4899
Source: Clin Med Res - June 12, 2023 Category: Research Authors: Yuta Mitobe Takeshi Itou Yuri Yamaguchi Tomomi Yoshioka Kenji Nakagawa Source Type: research
Diagnostic potential of serum miR-532-3p as a circulating biomarker for experimental intrinsic drug-induced liver injury by acetaminophen and cisplatin in rats
Food Chem Toxicol. 2023 Jun 10:113890. doi: 10.1016/j.fct.2023.113890. Online ahead of print.ABSTRACTEvaluating tissue injury largely depends on serum biochemical analysis despite insufficient tissue specificity and low sensitivity. Therefore, attention has been paid to the potential of microRNAs (miRNAs) to overcome the limitations of the current diagnostic tools, as tissue-enriched miRNAs are detected in the blood upon tissue injury. First, using a cisplatin-injected rats, we screened a specific pattern of altered hepatic miRNAs and their target mRNAs. Subsequently, we identified novel liver-specific circulating miRNAs f...
Source: Food and Chemical Toxicology - June 12, 2023 Category: Food Science Authors: Da-Bin Hwang Yoojin Seo Eunji Lee Dong-Hoon Won Changuk Kim MinHwa Kang Young Jeon Hyung-Sik Kim Jun Won Park Jun-Won Yun Source Type: research
Novel ruthenium-doped vanadium carbide/polymeric nanohybrid sensor for acetaminophen drug detection in human blood
Int J Biol Macromol. 2023 Jun 10:125329. doi: 10.1016/j.ijbiomac.2023.125329. Online ahead of print.ABSTRACTThe use of advanced electroactive catalysts enhances the performance of electrochemical biosensors in real-time biomonitoring and has received much attention owing to its excellent physicochemical and electrochemical possessions. In this work, a novel biosensor was developed based on the electrocatalytic activity of functionalized vanadium carbide (VC) material, including VC@ruthenium (Ru), VC@Ru-polyaniline nanoparticles (VC@Ru-PANI-NPs) as non-enzymatic nanocarriers for the fabrication of modified screen-printed el...
Source: International Journal of Biological Macromolecules - June 12, 2023 Category: Biochemistry Authors: Murugesan Duraisamy Mari Elancheziyan Muthusankar Eswaran Sivarasan Ganesan Anees A Ansari Govindaraj Rajamanickam Siew Ling Lee Pei-Chien Tsai Yi-Hsun Chen Vinoth Kumar Ponnusamy Source Type: research
Structural and performance variation of PES/PVDF membranes after exposure to the pretreated feed water of CECs
In this study, the removal efficiency of chemicals of emerging concerns (CECs) was evaluated under exposure to various doses of UV/H2O2-based oxidation processes in combination with membrane filtration for three cleaning cycles. Polyethersulphone (PES) and polyvinylidene fluoride (PVDF) materials based membranes were used for this study. The chemical cleaning of the membranes was performed by immersion of the membranes into 1 N HCl followed by adding 3000 mg.L-1 NaOCl for 1hr. Degradation and filtration performance was evaluated using Liquid Chromatography with tandem mass spectrometry (LC-MS/MS) and total organic carbon (...
Source: Chemosphere - June 9, 2023 Category: Chemistry Authors: Jun Young Kim Kang Hoon Lee Jae Won Lee Imtiaz Afzal Khan Jong-Oh Kim Source Type: research
Novel graphene electrochemical transistors incorporating zirconia inorganic molecular imprinted layer ：Design, construction and application for highly sensitive and selective detection of acetaminophen
Anal Chim Acta. 2023 Aug 15;1269:341405. doi: 10.1016/j.aca.2023.341405. Epub 2023 May 22.ABSTRACTOwing to their intrinsic amplifying effect together with chemical stability, graphene electrochemical transistor sensors (GECTs) are gaining momentum for sensing applications. However, the surface of GECTs for different detection substances must be modified with different recognition molecules, which was cumbersome and lack a universal method. Molecularly imprinted polymer (MIP) is a kind of polymer with specific recognition function for given molecules. Here, MIP and GECTs were combined to effectively solve the problem of wea...
Source: Analytica Chimica Acta - June 8, 2023 Category: Chemistry Authors: Nan Gao Junzi Pan Lei Wang Zhiwei Cai Gang Chang Yuxiang Wu Yunbin He Source Type: research
Aspartame and Phenylketonuria: an analysis of the daily phenylalanine intake of aspartame-containing drugs marketed in France
DISCUSSION: In situations requiring the use of these molecules, we propose as an alternative, the use of an aspartame-free form of these molecules or a form with a low Phe intake. If it is not possible, we propose as second-line the use of another antibiotics or analgesics. Finally, we have to remember the benefits-risk balance to use medications containing significant Phe intake in PKU patients. Indeed, it may be better to use a Phe containing medication in the absence of an aspartame-free form of this drug rather than to leave a person with PKU without treatment.PMID:37291632 | DOI:10.1186/s13023-023-02770-x
Source: Cancer Control - June 8, 2023 Category: Cancer & Oncology Authors: Victor Maler Violette Goetz Marine Tardieu Abderrahmane El Khalil Jean Meidi Alili Philippe Meunier Fran çois Maillot Fran çois Labarthe Source Type: research
