Aspartame and Phenylketonuria: an analysis of the daily phenylalanine intake of aspartame-containing drugs marketed in France

DISCUSSION: In situations requiring the use of these molecules, we propose as an alternative, the use of an aspartame-free form of these molecules or a form with a low Phe intake. If it is not possible, we propose as second-line the use of another antibiotics or analgesics. Finally, we have to remember the benefits-risk balance to use medications containing significant Phe intake in PKU patients. Indeed, it may be better to use a Phe containing medication in the absence of an aspartame-free form of this drug rather than to leave a person with PKU without treatment.PMID:37291632 | DOI:10.1186/s13023-023-02770-x

Source: Cancer Control - June 8, 2023 Category: Cancer & Oncology Authors: Victor Maler Violette Goetz Marine Tardieu Abderrahmane El Khalil Jean Meidi Alili Philippe Meunier Fran çois Maillot Fran çois Labarthe Source Type: research