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Gefitinib-induced Myositis: A Novel Case Report
Yakugaku Zasshi. 2023;143(7):617-620. doi: 10.1248/yakushi.23-00007.ABSTRACTChemotherapy-induced myositis is a severe adverse event caused by chemotherapeutic agents such as immune checkpoint inhibitors (ICIs) or cytotoxic agents. We experienced a patient with gefitinib-induced myositis with symptoms of muscle cramps and stiffness in the limbs, and reported the treatment process. A 70-year-old woman received four courses of carboplatin (CBDCA)+pemetrexed (PEM)+gefitinib (intravenous CBDCA area under the curve (AUC) 5 and PEM 500 mg/m2, every 3 weeks, and oral gefitinib 250 mg daily), for epidermal growth factor receptor (E...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 2, 2023 Category: Drugs & Pharmacology Authors: Tatsuhiko Sakamoto Yoshitaka Saito Yoh Takekuma Eiki Kikuchi Mitsuru Sugawara Source Type: research
