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Specialty: Neurology
Condition: Alzheimer's
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Total 647 results found since Jan 2013.
The Immunomodulatory Potential Role of Mesenchymal Stem Cells in Diseases of the Central Nervous System
CONCLUSION: It was shown that MSCs, independent from origin or administration pathway, can reduce inflammation and help in the recovery and preservation of injured neural tissue. Thus, the use of MSCs represents a potential therapeutic option in the treatment of neurological disorders mediated by inflammatory processes.PMID:36398461 | DOI:10.1159/000528036
Source: Neuro-Degenerative Diseases - November 18, 2022 Category: Neurology Authors: Rodrigo de Andrade Rufino La ís da Silva Pereira-Rufino Thays Cristina Silva Vissoto Irina Kerkis Adriana da Costa Neves Marcelo Cavenaghi Pereira da Silva Source Type: research
Bibliometric review of 1992 –2022 publications on acupuncture for cognitive impairment
ConclusionThis research provides valuable information for the study of acupuncture. Diseases focus on mild cognitive impairment (MCI), Alzheimer's disease (AD), and vascular dementia (VaD). Tauopathies with hyperphosphorylation of Tau protein as the main lesions also need to be paid attention to. The development of functional magnetic resonance imaging (fMRI) will better explain the therapeutic effect of acupuncture treatment. The effect of acupuncture on a single point is more convincing, and acupuncture on Baihui (GV20) may be needed in the future. Finally, the implementation of high-quality multicenter randomized contro...
Source: Frontiers in Neurology - September 26, 2022 Category: Neurology Source Type: research
Cytokine storm and neuropathological alterations in patients with neurological manifestations of COVID-19
Curr Alzheimer Res. 2022 Sep 8. doi: 10.2174/1567205019666220908084559. Online ahead of print.ABSTRACTThe COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2), a respiratory pathogen with neuroinvasive potential. Neurological COVID-19 manifestations include loss of smell and taste, headache, dizziness, stroke, and potentially fatal encephalitis. Several studies found elevated proinflammatory cytokines such as TNF-α, IFN-γ, IL-6 IL-8, IL-10 IL-16, IL-17A, and IL-18 in severely and critically ill COVID-19 patients, which may persist even after apparent recovery from infection. Bioma...
Source: Current Alzheimer Research - September 12, 2022 Category: Neurology Authors: Christos Tsagkaris Muhammad Bilal Irem Aktar Youssef Aboufandi Ahmet Tas Abdullahi Tunde Aborode Tarun Kumar Suvvari Shoaib Ahmad Anastasiia Shkodina Rachana Phadke Marwa S Emhamed Atif Amin Baig Athanasios Alexiou Ghulam Md Ashraf Mohammad Amjad Kamal Source Type: research
RNA sequencing uncover crucial genes mediating progression of large-artery atherosclerotic and small-artery occlusion ischemic stroke
CONCLUSION: This finding may help to understand the mechanisms of LAAIS and SAOIS and offer novel clues for finding specific biomarkers for LAAIS and SAOIS.PMID:36096198 | DOI:10.1016/j.brainres.2022.148078
Source: Brain Research - September 12, 2022 Category: Neurology Authors: Zhaolin Chen Duncai Wei Xiaopu Chen Yinting Huang Zibin Shen Wenzhen He Source Type: research
Cytokine storm and neuropathological alterations in patients with neurological manifestations of COVID-19
Curr Alzheimer Res. 2022 Sep 8. doi: 10.2174/1567205019666220908084559. Online ahead of print.ABSTRACTThe COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2), a respiratory pathogen with neuroinvasive potential. Neurological COVID-19 manifestations include loss of smell and taste, headache, dizziness, stroke, and potentially fatal encephalitis. Several studies found elevated proinflammatory cytokines such as TNF-α, IFN-γ, IL-6 IL-8, IL-10 IL-16, IL-17A, and IL-18 in severely and critically ill COVID-19 patients, which may persist even after apparent recovery from infection. Bioma...
Source: Current Alzheimer Research - September 12, 2022 Category: Neurology Authors: Christos Tsagkaris Muhammad Bilal Irem Aktar Youssef Aboufandi Ahmet Tas Abdullahi Tunde Aborode Tarun Kumar Suvvari Shoaib Ahmad Anastasiia Shkodina Rachana Phadke Marwa S Emhamed Atif Amin Baig Athanasios Alexiou Ghulam Md Ashraf Mohammad Amjad Kamal Source Type: research
RNA sequencing uncover crucial genes mediating progression of large-artery atherosclerotic and small-artery occlusion ischemic stroke
CONCLUSION: This finding may help to understand the mechanisms of LAAIS and SAOIS and offer novel clues for finding specific biomarkers for LAAIS and SAOIS.PMID:36096198 | DOI:10.1016/j.brainres.2022.148078
Source: Brain Research - September 12, 2022 Category: Neurology Authors: Zhaolin Chen Duncai Wei Xiaopu Chen Yinting Huang Zibin Shen Wenzhen He Source Type: research
Advanced molecular therapies for neurological diseases: focus on stroke, alzheimer's disease, and parkinson's disease
AbstractNeurological diseases (NDs) are one of the leading causes of disability and the second leading cause of death globally. Among these stroke, Alzheimer's disease (AD), and Parkinson's disease (PD) are the most common NDs. A rise in the absolute number of individuals affected with these diseases indicates that the current treatment strategies in management and prevention of these debilitating diseases are not effective sufficiently. Therefore, novel treatment strategies are being explored to cure these diseases by addressing the causative mechanisms at the molecular level. Advanced therapies like gene therapy (gene ed...
Source: Neurological Sciences - September 6, 2022 Category: Neurology Source Type: research
Genetics of Dravet Syndrome and its Targeted Therapy by Nanomedicine: A Roadmap for Future Treatment of Drug Resistant Seizures
Curr Mol Pharmacol. 2022 Aug 19. doi: 10.2174/1874467215666220819143105. Online ahead of print.ABSTRACTAccording to the World Health Organization (WHO), epilepsy is the 4th most prevalent neurological disorder after migraine, stroke, and Alzheimer's disease. There are numerous types of epileptic syndrome that are reported in children; one of them is Dravet syndrome. It is a neurological disorder of infants' outset during the first year of life. Dravet syndrome is a genetically determined syndrome and the most studied form of genetic epilepsy. Nearly 70-80% of its cases are due to genetic alterations in the SCN1A gene, and ...
Source: Epilepsy Curr - August 20, 2022 Category: Neurology Authors: Muhammad Ikram Sufian Rasheed Source Type: research
