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Specialty: Neurology
Condition: Alzheimer's
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Total 647 results found since Jan 2013.
Current Trends in the Animal Models for Screening of Nootropic Agents
CONCLUSION: Since a variety of etiologies can affect the cognitive processes, hence a nootropic agent may be screened in a variety of disease models. The most widely used and appropriate method to assess cognition would be by combining the behavioral and biochemical assays so that a more comprehensive profile about the nootropic effects of a drug can be elicited.PMID:35469584 | DOI:10.2174/2772432817666220425121323
Source: Epilepsy Curr - April 26, 2022 Category: Neurology Authors: Shubhima Grover Seema Jain Source Type: research
Effect of retinoic acid on the neurovascular unit: A review
Brain Res Bull. 2022 Mar 26:S0361-9230(22)00080-6. doi: 10.1016/j.brainresbull.2022.03.011. Online ahead of print.ABSTRACTRetinoic acid is a metabolic product derived from vitamin A, acting at a nuclear level to maintain the proper transcriptional activity. Moreover, this molecule contributes to the development and maturation of the cerebral vascular system, playing a pivotal role in development and maintenance of neurovascular unit integrity. This physiological structure is comprised of glial cells, vascular cells, and neurons, ensuring the correct function of the blood-brain barrier and, at last instance, the homeostasis...
Source: Brain Research Bulletin - March 30, 2022 Category: Neurology Authors: Manuel R Pouso Elisa Cairrao Source Type: research
A Review on the Arylpiperazine Derivatives as Potential Therapeutics for the Treatment of Various Neurological Disorders
Curr Drug Targets. 2022 Jan 17. doi: 10.2174/1389450123666220117104038. Online ahead of print.ABSTRACTNeurological disorders are disease conditions related to the neurons and central nervous system (CNS). Any kind of structural, electrical, biochemical and functional abnormalities in neurons can lead to various types of disorders like Alzheimer's disease (AD), depression, Parkinson's disease (PD), epilepsy, stroke, etc. Currently available medicines are symptomatic and do not treat the disease state. Thus, novel CNS active agents with the potential of complete treatment of an illness are highly desired. A range of small or...
Source: Epilepsy Curr - March 21, 2022 Category: Neurology Authors: Bhupinder Kumar Naveen Kumar Amandeep Thakur Vijay Kumar Rakesh Kumar Vinod Kumar Source Type: research
