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Total 1309 results found since Jan 2013.

Middle School Students Effectively Improve Stroke Knowledge and Pass Them to Family Members in China Using Stroke 1-2-0
Conclusion: Middle school and high school students can effectively use Stroke 1-2-0 to improve their stroke knowledge and pass this knowledge to their family members. Sustained educational efforts and repeated educational events are needed though.
Source: Frontiers in Neurology - April 7, 2020 Category: Neurology Source Type: research

Stroke Rehabilitation
This article reviews and summarizes the key concepts related to poststroke recovery. Recent Findings: Good data now exist by which one can predict recovery, especially motor recovery, very soon after stroke onset. Recent trials have not demonstrated a clear benefit associated with very early initiation of rehabilitative therapy after stroke in terms of improvement in poststroke outcomes. However, growing evidence suggests that shorter and more frequent sessions of therapy can be safely started in the first 24 to 48 hours after a stroke. The optimal amount or dose of therapy for stroke remains undetermined, as more intensi...
Source: CONTINUUM: Lifelong Learning in Neurology - February 1, 2017 Category: Neurology Tags: Review Articles Source Type: research

Retention of Stroke Education Provided during Hospitalization: Does Provision of Required Education Increase Stroke Knowledge?
Discussion: While stroke education is required during hospitalization, its ability to produce retention may be poor. We propose study of test-enhanced learning methods through the Targeted Education in Stroke Trial (TEST) to examine the effect of novel teaching methods on patient/caregiver knowledge retention.Intervent Neurol 2018;7:471 –478
Source: Interventional Neurology - July 26, 2018 Category: Neurology Source Type: research

Clustering and prediction of long-term functional recovery patterns in first-time stroke patients
ConclusionsThe longitudinal, multi-dimensional, functional assessment data of first-time stroke patients were successfully clustered, and the prediction models showed relatively good accuracies. Early identification and prediction of long-term functional outcomes will help clinicians develop customized treatment strategies.
Source: Frontiers in Neurology - March 8, 2023 Category: Neurology Source Type: research

Machine learning models of plasma proteomic data predict mood in chronic stroke and tie it to aberrant peripheral immune responses
Brain Behav Immun. 2023 Aug 7:S0889-1591(23)00225-8. doi: 10.1016/j.bbi.2023.08.002. Online ahead of print.ABSTRACTPost-stroke depression is common, long-lasting and associated with severe morbidity and death, but mechanisms are not well-understood. We used a broad proteomics panel and developed a machine learning algorithm to determine whether plasma protein data can predict mood in people with chronic stroke, and to identify proteins and pathways associated with mood. We used Olink to measure 1,196 plasma proteins in 85 participants aged 25 and older who were between 5 months and 9 years after ischemic stroke. Mood was a...
Source: Brain, Behavior, and Immunity - August 9, 2023 Category: Neurology Authors: Neda H Bidoki Kristy A Zera Huda Nassar Lauren L Drag Michael Mlynash Elizabeth Osborn Muhith Musabbir Da Eun K Kim Maria Paula Mendez Maarten G Lansberg Nima Aghaeepour Marion S Buckwalter Source Type: research

Crew resource management and simulator training in acute stroke therapy.
CONCLUSION: Even though our data do not allow positive effects on patient outcomes to be inferred, the implementation of a CRM-based stroke team and simulator training has had multiple positive effects on the workflow and work satisfaction in the treatment of acute stroke patients. PMID: 27431675 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - July 17, 2016 Category: Neurology Authors: Tahtali D, Bohmann F, Rostek P, Misselwitz B, Reihs A, Heringer F, Jahnke K, Steinmetz H, Pfeilschifter W Tags: Nervenarzt Source Type: research

Aura and Stroke: relationship and what we have learnt from preclinical models
ConclusionPreclinical models suggest a key role for enhanced SD susceptibility and microembolization to explain both the occurrence of migraine attacks and the increased stroke risk in migraineurs. Therapeutic targeting of SD and microembolic events, or potential causes thereof, will be promising for treatment of aura and may also prevent ischemic infarction in vulnerable brains.
Source: The Journal of Headache and Pain - May 28, 2019 Category: Neurology Source Type: research

Expression of Cytokines and Chemokines as Predictors of Stroke Outcomes in Acute Ischemic Stroke
Conclusions: Machine learning algorithms can be employed to develop prognostic predictive biomarkers for stroke outcomes in ischemic stroke patients, particularly in regard to identifying acute gene expression changes that occur during stroke.
Source: Frontiers in Neurology - January 14, 2020 Category: Neurology Source Type: research

AIM2 inflammasome contributes to brain injury and chronic post-stroke cognitive impairment in mice.
Abstract Although over one-third of stroke patients may develop post-stroke cognitive impairment (PSCI), the mechanisms underlying PSCI remain unclear. We explored here, the involvement of post-stroke inflammasomes in long-term PSCI development, using a 45 min-middle cerebral artery occlusion (MCAO)/reperfusion-induced PSCI model. Immunohistological assessment on day 1, 3, and 7 was followed by cognitive function test 28 days post-stroke. Evaluation of inflammasome sensor gene expression in aged mouse brains showed dominant expression of absent in melanoma 2 (Aim2) in 6-, 12-, and 18-month-old mouse brains. AIM2 m...
Source: Brain, Behavior, and Immunity - March 18, 2020 Category: Neurology Authors: Kim H, Seo JS, Lee SY, Ha KT, Choi BT, Shin YI, Ju Yun Y, Shin HK Tags: Brain Behav Immun Source Type: research

Prediction-Driven Decision Support for Patients With Mild Stroke: A Model Based on Machine Learning Algorithms
Conclusions: DAMS and R-DAMS, as prediction-driven decision support tools, were designed to aid clinical decision-making for mild stroke patients in emergency contexts. In addition, even within a narrow range of baseline scores, NIHSS on admission is the strongest feature that contributed to the prediction.
Source: Frontiers in Neurology - December 23, 2021 Category: Neurology Source Type: research

Tissue hypoxia during ischemic stroke: Adaptive clues from hypoxia-tolerant animal models.
We describe specific physiological and molecular adaptations employed by different animals' models of hypoxia tolerance in aquatic and terrestrial environments. We highlight how these adaptations might provide potential clues on strategies to adapt for the clinical management of tissue hypoxia during conditions such as stroke where oxygen demand fails to match the supply. PMID: 25738761 [PubMed - as supplied by publisher]
Source: Brain Research Bulletin - March 1, 2015 Category: Neurology Authors: Nathaniel TI, Williams-Hernandez A, Hunter LA, Liddy C, Peffley DM, Imeh-Nathaniel A Tags: Brain Res Bull Source Type: research

A study on the natural history of scanning behaviour in patients with visual field defects after stroke
DiscussionThe longitudinal comparison of patients who do and do not learn compensatory scanning techniques may reveal important prognostic markers of natural recovery. Importantly, it may also help to determine the most effective treatment window for visual rehabilitation.
Source: BMC Neurology - April 24, 2015 Category: Neurology Authors: Tobias LoetscherCelia ChenSophie WignallAndreas BullingSabrina HoppeOwen ChurchesNicole ThomasMichael NichollsAndrew Lee Source Type: research

Association between genetic variation in the dopamine system and motor recovery after stroke.
CONCLUSION: These data suggest that genetic variation of dopamine-related genes may affect motor recovery after stroke and that COMT polymorphism could be useful for predicting motor recovery. PMID: 27689550 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - October 2, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research