Bailout Strategies and Complications Associated with the Use of Flow-Diverting Stents for Treating Intracranial Aneurysms
Background: Flow-diverting stents (FDS) have revolutionized the endovascular management of unruptured, complex, wide-necked, and giant aneurysms. There is no consensus on management of complications associated with the placement of these devices. This review focuses on the management of complications of FDS for the treatment of intracranial aneurysms.Summary: We performed a systematic, qualitative review using electronic databases MEDLINE and Google Scholar. Complications of FDS placement generally occur during the perioperative period.Key Message: Complications associated with FDS may be divided into periprocedural compli...
Source: Interventional Neurology - October 16, 2018 Category: Neurology Source Type: research

Acknowledgement to Reviewers
Intervent Neurol 2018;7:556 (Source: Interventional Neurology)
Source: Interventional Neurology - October 9, 2018 Category: Neurology Source Type: research

Contents Vol. 7, 2018
Intervent Neurol 2018;7:I –VI (Source: Interventional Neurology)
Source: Interventional Neurology - October 9, 2018 Category: Neurology Source Type: research

Does the Addition of Non-Approved Inclusion and Exclusion Criteria for rtPA Impact Treatment Rates? Findings in Australia, the UK, and the USA
Conclusions: Non-standard criteria for rtPA eligibility were evident in all three countries and could, in part, explain comparably low use of rtPA. Differences in the use of standard criteria may signify practitioner intolerance for those derived from original efficacy studies that are no longer relevant.Intervent Neurol 2019;8:1 –12 (Source: Interventional Neurology)
Source: Interventional Neurology - October 5, 2018 Category: Neurology Source Type: research

Recanalization of Tandem Vertebrobasilar Occlusions with Contralateral Vertebral Occlusion or Hypoplasia via either Direct Passage or the SHERPA Technique
Conclusion: Recanalization of tandem vertebrobasilar occlusions with contralateral occlusion or hypoplasia is feasible. Intracranial recanalization is facilitated by the passage of a long 6F sheath into V2, and retrograde delineation of an occluded vertebral origin with a microwire may serve as a crucial adjunct.Intervent Neurol 2019;8:13 –19 (Source: Interventional Neurology)
Source: Interventional Neurology - October 5, 2018 Category: Neurology Source Type: research

In vitro Remote Aspiration Embolectomy for the Treatment of Acute Ischemic Stroke
Conclusions: In a noncollapsible system, remote aspiration can be successfully achieved even in the setting of prominent branch arteries by using relatively large aspiration catheters. Proximal flow arrest may facilitate successful remote aspiration for some catheter sizes.Intervent Neurol 2019;8:20 –26 (Source: Interventional Neurology)
Source: Interventional Neurology - October 5, 2018 Category: Neurology Source Type: research

Endovascular Reperfusion for Acute Isolated Cervical Carotid Occlusions: The Concept of “Hemodynamic Thrombectomy”
Conclusions: The endovascular recanalization of isolated cervical carotid occlusions presenting with acute ischemic stroke symptoms is feasible. Because isolated cervical carotid occlusions are associated with hemodynamic ischemic symptoms, if carotid recanalization cannot be achieved, stenting other cervical arteries ’ stenoses, with a focus on intracranial flow improvement, appears to be a reasonable strategy. Large controlled studies are necessary to assess the safety and efficacy of recanalization of acute isolated cervical carotid occlusions.Intervent Neurol 2019;8:27 –37 (Source: Interventional Neurology)
Source: Interventional Neurology - October 5, 2018 Category: Neurology Source Type: research

Aortic Arch Variants: A Practical Guide to Safe and Timely Catheterization
Conclusion: Familiarity with more and less common arch variants, along with low threshold for performance of pigtail aortic arch angiography and comfort in use of general purpose and recurved catheters, will ensure success in the vast majority of encountered variations.Intervent Neurol 2018;7:544 –555 (Source: Interventional Neurology)
Source: Interventional Neurology - September 17, 2018 Category: Neurology Source Type: research

Regional Contributions to Poststroke Disability in Endovascular Therapy
Conclusions: For both right and left hemisphere, preservation of the high cortical regions was more strongly associated with improved outcomes compared to the deep regions. Our findings support taking into consideration the location and relative weightings of the involved ASPECTS regions when evaluating a patient for EST.Intervent Neurol 2018;7:533 –543 (Source: Interventional Neurology)
Source: Interventional Neurology - September 7, 2018 Category: Neurology Source Type: research

Comparison of Subacute Vascular Damage Caused by ADAPT versus Stent Retriever Devices after Thrombectomy in Acute Ischemic Stroke: Histological and Ultrastructural Study in an Animal Model
Conclusions: Both techniques caused damage to the vessel wall. The main damages were localized at the level of the tunica media and adventitia, instead of the tunica intima as in the acute phase. Further investigation is required to better understand whether these alterations could have chronic consequences.Intervent Neurol 2018;7:501 –512 (Source: Interventional Neurology)
Source: Interventional Neurology - September 2, 2018 Category: Neurology Source Type: research

Ghost Infarct Core and Admission Computed Tomography Perfusion: Redefining the Role of Neuroimaging in Acute Ischemic Stroke
Conclusions: CTP CBF #x3c; 30% may overestimate infarct core volume, especially in patients imaged in the very early time window and with fast complete reperfusion. Therefore, the CTP CBF technique may exclude patients who would benefit from endovascular treatment.Intervent Neurol 2018;7:513 –521 (Source: Interventional Neurology)
Source: Interventional Neurology - September 2, 2018 Category: Neurology Source Type: research

2D Parametric Parenchymal Blood Flow as a Predictor of the Hemorrhagic Events after Endovascular Treatment of Acute Ischemic Stroke: A Single-Center Retrospective Study
Conclusions: Elevated parametric parenchymal blood flow wash-in rates after thrombectomy may be associated with increased risk of hemorrhagic events.Intervent Neurol 2018;7:522 –532 (Source: Interventional Neurology)
Source: Interventional Neurology - September 2, 2018 Category: Neurology Source Type: research

Isolated Intraventricular Hemorrhage Associated with Cerebral Vasospasm and Delayed Cerebral Ischemia following Arteriovenous Malformation Rupture
Background: Although it is well characterized in aneurysmal subarachnoid hemorrhage, vasospasm is exceedingly rare following cerebral arteriovenous malformation (AVM) rupture. Subsequently, this complication is poorly characterized with regard to delayed cerebral ischemia (DCI). We review cases of ruptured AVM to assess the frequency and severity of vasospasm on cerebral angiography, and DCI.Summary: We reviewed our institutional database of acute intracranial hemorrhages between 2005 and 2014. We identified patients with cerebral AVM rupture and evidence of vasospasm, which was confirmed with digital subtraction angiograp...
Source: Interventional Neurology - July 31, 2018 Category: Neurology Source Type: research

Stent Survival and Stent-Adjacent Stenosis Rates following Venous Sinus Stenting for Idiopathic Intracranial Hypertension: A Systematic Review and Meta-Analysis
Conclusion: Stent-adjacent stenosis is an important complication following venous stenting in patients with DVSS and IIH. Further studies are needed to identify determinants of stent-adjacent stenosis and stent nonsurvival.Intervent Neurol 2018;7:490 –500 (Source: Interventional Neurology)
Source: Interventional Neurology - July 31, 2018 Category: Neurology Source Type: research

Retention of Stroke Education Provided during Hospitalization: Does Provision of Required Education Increase Stroke Knowledge?
Discussion: While stroke education is required during hospitalization, its ability to produce retention may be poor. We propose study of test-enhanced learning methods through the Targeted Education in Stroke Trial (TEST) to examine the effect of novel teaching methods on patient/caregiver knowledge retention.Intervent Neurol 2018;7:471 –478 (Source: Interventional Neurology)
Source: Interventional Neurology - July 26, 2018 Category: Neurology Source Type: research

Geospatial Visualization of Mobile Stroke Unit Dispatches: A Method to Optimize Service Performance
Conclusion: Our findings will facilitate determination of socio-spatial antecedents of neighborhood overutilization of 911 and MSU services in our urban neighborhoods and service delivery optimization to reach neighborhoods with true stroke burden.Intervent Neurol 2018;7:464 –470 (Source: Interventional Neurology)
Source: Interventional Neurology - July 24, 2018 Category: Neurology Source Type: research

Incidence of Aneurysmal Subarachnoid Hemorrhage with Procedures Requiring General Anesthesia in Patients with Unruptured Intracranial Aneurysms
Conclusion: In our study, general anesthesia did not precipitate aneurysm rupture, and there were no instances of subarachnoid hemorrhage during the follow-up period. Our results suggest a benign natural history for aneurysms undergoing unrelated general anesthesia. However, this should be interpreted with caution given limitations related to our small sample size and retrospective study design.Intervent Neurol 2018;7:452 –456 (Source: Interventional Neurology)
Source: Interventional Neurology - July 18, 2018 Category: Neurology Source Type: research

Usefulness of Cone Beam Intra-Arterial CTA for Evaluation of Flow Diverters: A Practical Approach for Daily Use
Cone beam computed tomography (CBCT), initially used for evaluation of intraprocedural complications such as hemorrhage, has evolved to provide details of implanted devices such as flow diverters. The study aim is to present our experience in using CBCT with intra-arterial injection and provide a step-by-step approach for postprocessing in a practical protocol for daily use. IRB approval was obtained, and the neurointerventional database was retrospectively reviewed from July 2012 to June 2017. Patients who underwent cone beam intra-arterial CT angiography for evaluation of implanted flow diverter devices were reviewed. Pa...
Source: Interventional Neurology - July 18, 2018 Category: Neurology Source Type: research

Safety and Feasibility of Balloon-Assisted Embolization with Onyx of Brain Arteriovenous Malformations Revisited: Personal Experience with the Scepter XC Balloon Microcatheter
Conclusion: Utilization of the extra-compliant balloon microcatheter results in safe and effective BAE, which adds to the growing experience with BAE for AVM treatment.Intervent Neurol 2018;7:439 –444 (Source: Interventional Neurology)
Source: Interventional Neurology - July 13, 2018 Category: Neurology Source Type: research

Acute Ischemic Stroke due to Common Carotid Ostial Disease with Tandem Intracranial Occlusions Treated with Thrombectomy and Staged Retrograde Stenting
We present the first 2 cases of acute ischemic stroke secondary to common carotid ostial disease with tandem intracranial occlusion, treated with intracranial thrombectomy followed by subsequent staged balloon-mounted stenting of the common carotid ostium. We review the pathophysiology of tandem occlusions, the controversy surrounding treatment techniques, and various approaches used in the treatment of ostial occlusive lesions.Key Message: In certain situations where acute carotid stenting is not safe or technically possible, immediate intracranial thrombectomy with a subsequent staged balloon-mounted stenting of the osti...
Source: Interventional Neurology - July 13, 2018 Category: Neurology Source Type: research

Multicenter Experience with Stenting for Symptomatic Carotid Web
Conclusions: Stenting for symptomatic CaW appears to be a safe and effective alternative to surgical resection. Further studies are warranted.Intervent Neurol 2018;7:413 –418 (Source: Interventional Neurology)
Source: Interventional Neurology - July 11, 2018 Category: Neurology Source Type: research

Neurointerventional “Near Morbidity”: A Candid Appraisal of an Early Case Series
Conclusions:“Minor”/technical complications – NNM – can be as instructive and illustrative as major complications despite not resulting in permanent morbidity. In reviewing case series, particularly early in one’s career, these cases should be highlighted.Intervent Neurol 2018;7:419 –430 (Source: Interventional Neurology)
Source: Interventional Neurology - July 11, 2018 Category: Neurology Source Type: research

Endovascular Therapy versus Thrombolysis in Patients with Mild Strokes and Large Vessel Occlusions within the Anterior Circulation
Conclusion: Compared with IVT, the routine use of ET did not significantly improve the early clinical or radiological outcome in patients with mild strokes and anterior circulation large vessel occlusions. Further randomized trials are urgently needed to determine the role of ET in this cohort.Intervent Neurol 2018;7:431 –438 (Source: Interventional Neurology)
Source: Interventional Neurology - July 11, 2018 Category: Neurology Source Type: research

Direct Thrombectomy versus Bridging for Patients with Emergent Large-Vessel Occlusions
Conclusions: The chances of attaining excellent functional outcomes are similar in ELVO patients undergoing dEVT or bridging.Intervent Neurol 2018;7:403 –412 (Source: Interventional Neurology)
Source: Interventional Neurology - July 4, 2018 Category: Neurology Source Type: research

Cervical Origin of the Right Subclavian Artery with a Nonbifurcating Left Cervical Carotid Artery
Intervent Neurol 2018;7:399 –402 (Source: Interventional Neurology)
Source: Interventional Neurology - June 22, 2018 Category: Neurology Source Type: research

Endovascular Therapy and Ethnic Disparities in Stroke Outcomes
Conclusions: Despite unique baseline characteristics, African-Americans treated with ET for large vessel occlusion strokes have similar outcomes as Caucasians. Greater availability of ET may diminish the ethnic/racial disparities in stroke outcomes.Intervent Neurol 2018;7:389 –398 (Source: Interventional Neurology)
Source: Interventional Neurology - June 19, 2018 Category: Neurology Source Type: research

Carotid Revascularization with and without the Use of an Embolic Protection Device: A Single-Center Experience from Pakistan
Conclusion: Based on our single-center experience and findings of a relatively small sample size, carotid revascularization with stenting and angioplasty without EPD in experienced hands was found to be safe and efficacious. In addition, it proves cost-effective for patients by limiting the use of unnecessary disposables. These results are comparable to those reported in major trials and are well within the complication thresholds suggested in current guidelines. These results also show promise and illustrate the need for a larger, randomized controlled trial in order to thoroughly address this aspect of carotid revascular...
Source: Interventional Neurology - June 11, 2018 Category: Neurology Source Type: research

Active Reperfusion Hemorrhage during Thrombectomy: Angiographic Findings and Real-Time Correlation with the CT “Spot Sign”
Conclusions: Active reperfusion hemorrhage involving perforator arteries was observed to correlate with the CT “spot sign” and to be associated with poor outcomes.Intervent Neurol 2018;7:370 –377 (Source: Interventional Neurology)
Source: Interventional Neurology - June 8, 2018 Category: Neurology Source Type: research

Pipeline Embolization for Salvage Treatment of Previously Stented Residual and Recurrent Cerebral Aneurysms
Conclusions: Salvage flow diversion for previously stented aneurysms is technically challenging but offers good prospects of aneurysm obliteration with acceptable complication rates.Intervent Neurol 2018;7:359 –369 (Source: Interventional Neurology)
Source: Interventional Neurology - June 1, 2018 Category: Neurology Source Type: research

Seeing Is Believing: Headway27 as a Highly Visible and Versatile Microcatheter with Ideal Dimensions for Stroke Thrombectomy
Conclusion: The Headway27 microcatheter reliably facilitated rapid clot access in anterior and posterior circulation acute large vessel occlusions with no microcatheter-associated complications.Intervent Neurol 2018;7:341 –346 (Source: Interventional Neurology)
Source: Interventional Neurology - May 31, 2018 Category: Neurology Source Type: research

Review of the Mobile Stroke Unit Experience Worldwide
Background: The treatment of stroke is dependent on a narrow therapeutic time window that requires interventions to be emergently pursued. Despite recent “FAST” initiatives that have underscored “time is brain,” many patients still fail to present within the narrow time window to receive maximum treatment benefit from advanced stroke therapies, including recombinant tissue plasminogen activator (tPA) and mechanical thrombectomy. The convergen ce of emergency medical services, telemedicine, and mobile technology, including transportable computed tomography scanners, has presented a unique opportunity...
Source: Interventional Neurology - May 31, 2018 Category: Neurology Source Type: research

Automated CT Perfusion Prediction of Large Vessel Acute Stroke from Intracranial Atherosclerotic Disease
Conclusion: An automated CTP Tmax #x3e; 4 s/Tmax #x3e; 6 s ratio ≥2 profile was found independently associated with underlying ICAD LVOS.Intervent Neurol 2018;7:334 –340 (Source: Interventional Neurology)
Source: Interventional Neurology - May 17, 2018 Category: Neurology Source Type: research

A Serpiginous Pericallosal Anterior Cerebral Artery
The anterior cerebral artery (ACA) is a unique artery with many important variations with substantial clinical significance. Tortuous intracranial arteries usually occur in basilar, communicating, anterior, posterior cerebral arteries and in the white matter arterioles. This could happen for many reasons including but not limited to ageing, hypertension, patients with Moyamoya disease, congenital malformation, or increased flow associated with elastin degradation. While dolichoectasia of the ACA has been described even in children, to our knowledge, a serpiginous ACA without ectasia has not been reported, especially in the...
Source: Interventional Neurology - May 16, 2018 Category: Neurology Source Type: research

Endovascular Acute Ischemic Stroke Treatment with FlowGate Balloon Guide Catheter: A Single-Center Observational Study of FlowGate Balloon Guide Catheter Use
Conclusions: Use of the FlowGate BGC as an adjunct to mechanical thrombectomy was associated with good FPE and an overall recanalization of TICI 2b/3 of 94%.Intervent Neurol 2018;7:327 –333 (Source: Interventional Neurology)
Source: Interventional Neurology - May 16, 2018 Category: Neurology Source Type: research

5-French SOFIA: Safe Access and Support in the Anterior Cerebral Artery, Posterior Cerebral Artery, and Insular Middle Cerebral Artery
Conclusion: The 5-French SOFIA can be safely utilized for distal, superselective catheterization in the context of complex neurointervention, including aneurysm and arteriovenous shunt embolization and distal thrombectomy.Intervent Neurol 2018;7:308 –314 (Source: Interventional Neurology)
Source: Interventional Neurology - May 3, 2018 Category: Neurology Source Type: research

Transvenous Embolization of Dural Arteriovenous Fistulas of the Hypoglossal Canal: Report of Three Cases and Review of the Literature
In this article, we report three cases of dural arteriovenous fistulas of the hypoglossal canal treated via transvenous approach. We also perform a review of the literature on the endovascular management of this type of lesions with particular attention to the dangerous extracranial-intracranial anastomoses that can occur at this level.Intervent Neurol 2018;7:315 –322 (Source: Interventional Neurology)
Source: Interventional Neurology - May 3, 2018 Category: Neurology Source Type: research

High-Risk Features of Delayed Clinical Progression in Cerebral Venous Thrombosis: A Proposed Prediction Score for Early Intervention
Conclusions: Decreased mental status, seizure activity, papilledema, number of involved sinuses, as well as sodium level and platelet count are the most important factors in predicting deterioration after CVT. This group may represent a subset of patients in whom early endovascular therapy may be considered.Intervent Neurol 2018;7:297 –307 (Source: Interventional Neurology)
Source: Interventional Neurology - April 20, 2018 Category: Neurology Source Type: research

Epidemiology of Intracranial Hemorrhage Associated with Oral Anticoagulants in Spain: Trends in Anticoagulation Complications Registry – The TAC 2 Study
Conclusion: We found that the incidence of OAC-induced ICH was greater than in previous studies. Hemorrhage volume and mortality were lower in ICH-DOACs than in ICH-VKAs. After stroke, DOACs were the most frequently indicated antithrombotic treatment.Intervent Neurol 2018;7:284 –295 (Source: Interventional Neurology)
Source: Interventional Neurology - April 4, 2018 Category: Neurology Source Type: research

Acute In-Stent Thrombosis after Carotid Angioplasty and Stenting: A Case Report and Literature Review
Conclusion: Acute carotid stent thrombosis (ACST) can have devastating effects on the survival of the patient. For ACST when the stent does not fully adhere to the blood vessel, a mechanical approach should be a feasible solution to the problem.Intervent Neurol 2018;7:265 –270 (Source: Interventional Neurology)
Source: Interventional Neurology - April 3, 2018 Category: Neurology Source Type: research

LVIS Jr Device for Y-Stent-Assisted Coil Embolization of Wide-Neck Intracranial Aneurysms: A Multicenter Experience
Conclusions: In this multicenter case series, Y-stent-assisted coiling of wide-neck aneurysms with the LVIS Jr device was feasible and relatively safe. Follow-up imaging demonstrated very low recanalization rates.Intervent Neurol 2018;7:271 –283 (Source: Interventional Neurology)
Source: Interventional Neurology - April 3, 2018 Category: Neurology Source Type: research

Progressive Neurological Decline with Deep Bilateral Imaging Changes: A Protean Presentation of Dural Arteriovenous Fistulae
We describe here a case series of 4 patients with deep cerebral DAVF who presented with impaired arousal or memory and behavioral changes. In all patients, the initial differential diagnosis included metabolic, inflammatory, infectious, or neoplastic disease, with an eventual correct diagnosis obtained after catheter angiography had demonstrated arterialization of the deep venous structures, including the vein of Galen. All patients were successfully treated with endovascular embolization, with 1 patient requiring additional surgical treatment. We review the contemporary diagnostic evaluation and management of DAVF within ...
Source: Interventional Neurology - March 27, 2018 Category: Neurology Source Type: research

Mechanical Thrombectomy in Elderly Stroke Patients with Mild-to-Moderate Baseline Disability
Conclusion: Advanced age, baseline disability, and delayed treatment are associated with sub ­optimal outcomes after MT. However, redefining good outcome to include return to baseline functioning demonstrates that one-third of this patient population benefits from MT, suggesting the real-life utility of this treatment.Intervent Neurol 2018;7:246 –255 (Source: Interventional Neurology)
Source: Interventional Neurology - March 20, 2018 Category: Neurology Source Type: research

Support of New Triage Protocol among Acute Stroke Care Providers
Conclusion: Among the survey responders, there is a broad acceptance of the idea of bypassing ACH and going straight to ECH when LVO is suspected; however, there is less agreement on triaging patients with non-LVO stroke.Intervent Neurol 2018;7:241 –245 (Source: Interventional Neurology)
Source: Interventional Neurology - March 14, 2018 Category: Neurology Source Type: research

Abciximab (ReoPro) Dosing Strategy for the Management of Acute Intraprocedural Thromboembolic Complications during Pipeline Flow Diversion Treatment of Intracranial Aneurysms
Conclusions: IA ReoPro administration is an effective and safe rescue strategy for the management of acute intraprocedural thromboembolic complications during PED treatment. Using a dosing strategy of either 5-mg increments or a 0.125 mg/kg IA bolus (half cardiac dosing) can provide high rates of recanalization with low rates of hemorrhagic complications and long-term morbidity.Intervent Neurol 2018;7:218 –232 (Source: Interventional Neurology)
Source: Interventional Neurology - February 27, 2018 Category: Neurology Source Type: research

Carotid Stenting for Treatment of Symptomatic Carotid Webs: A Single-Center Case Series
Conclusions: Stent placement for treatment of carotid webs can be performed safely. Further studies are needed to confirm our findings.Intervent Neurol 2018;7:233 –240 (Source: Interventional Neurology)
Source: Interventional Neurology - February 22, 2018 Category: Neurology Source Type: research

Preclinical Evaluation of the NeVaTM Stent Retriever: Safety and Efficacy in the Swine Thrombectomy Model
Conclusions: Our preclinical results support the use of the NeVaTM device in a clinical trial to determine if this novel design improves upon current stent retriever outcomes.Intervent Neurol 2018;7:205 –217 (Source: Interventional Neurology)
Source: Interventional Neurology - February 14, 2018 Category: Neurology Source Type: research

Pomona Large Vessel Occlusion Screening Tool for Prehospital and Emergency Room Settings
Conclusion: The Pomona Scale is a simple and accurate scale to predict LVO. In addition, the presence of either gaze deviation or neglect also suggests the possibility of LVO.Intervent Neurol 2018;7:196 –203 (Source: Interventional Neurology)
Source: Interventional Neurology - February 13, 2018 Category: Neurology Source Type: research

Preclinical Evaluation of the NeVa < sup > TM < /sup > Stent Retriever: Safety and Efficacy in the Swine Thrombectomy Model
Conclusions: Our preclinical results support the use of the NeVaTM device in a clinical trial to determine if this novel design improves upon current stent retriever outcomes.Intervent Neurol 2018;7:205 –217 (Source: Interventional Neurology)
Source: Interventional Neurology - February 13, 2018 Category: Neurology Source Type: research

47 Consecutive Cases of Pipeline Flex Flow Diversion Utilizing a Novel Large-Bore Intracranial Intermediate Catheter: Nuances and Institutional Experience with the Syphontrak
Conclusion: The Syphontrak is a new large-bore, multi-durometer intermediate catheter (IC) designed for use in modern neurointerventional procedures. We have shown its utility in 47 successful cases of PED Flex flow diversion of a wide range of complexity. The IC provides robust and atraumatic distal intracranial access while also providing an enhanced image quality with its large 0.060 ″ inner diameter.Intervent Neurol 2018;7:153 –163 (Source: Interventional Neurology)
Source: Interventional Neurology - February 9, 2018 Category: Neurology Source Type: research

A Review of Pre-Intervention Prognostic Scores for Early Prognostication and Patient Selection in Endovascular Management of Large Vessel Occlusion Stroke
Background: Endovascular therapy (ET) has emerged as a highly effective treatment for acute large vessel occlusion stroke (LVOS). Tools that facilitate optimal patient selection of patients for ET are needed in order to maximize therapeutic benefit in a cost-effective manner. Several pre-intervention prognostic scores for prediction of outcomes in LVOS patients and patient selection for ET have been developed and validated, but their clinical use has been limited. Here, we review existing pre-intervention prognostic scores, compare their prognostic accuracies and levels of validation and identify gaps in current knowledge....
Source: Interventional Neurology - February 7, 2018 Category: Neurology Source Type: research